{"id":13926,"date":"2024-11-05T12:05:42","date_gmt":"2024-11-05T17:05:42","guid":{"rendered":"https:\/\/www.med.unc.edu\/cellbiophysio\/?post_type=tribe_events&p=13926"},"modified":"2024-11-05T12:05:42","modified_gmt":"2024-11-05T17:05:42","slug":"fall-2024-seminar-series-francisco-laurindo-md-phd","status":"publish","type":"tribe_events","link":"https:\/\/www.med.unc.edu\/cellbiophysio\/event\/fall-2024-seminar-series-francisco-laurindo-md-phd\/","title":{"rendered":"Fall 2024 Seminar Series – Francisco Laurindo, MD, PhD"},"content":{"rendered":"
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\"A<\/p>\n<\/div>\n

\nFrancisco Laurindo, MD, PhD<\/b><\/p>\n
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Professor, Heart Institute (Incor) & Director, Vascular Biology Laboratory<\/p>\n<\/div>\n

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University of S\u00e3o Paulo<\/p>\n<\/div>\n

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President, Society for Redox Biology and Medicine<\/p>\n

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Research focus<\/strong><\/p>\n<\/div>\n

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An endoplasmic reticulum-centered model for redox-dependent intercellular communication<\/p>\n

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Faculty hosts<\/strong><\/p>\n<\/div>\n

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Edward Bahnson<\/a>, PhD and Sharon Campbell<\/a>, PhD<\/p>\n<\/div>\n<\/div>\n

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More information on speaker\u00a0<\/strong><\/p>\n

Francisco Laurindo<\/a> is pioneer in redox signaling and cardiovascular biology. He earned his medical degree from the University of S\u00e3o Paulo School of Medicine in 1978 and completed his residence training in internal medicine and cardiology at the University of S\u00e3o Paulo School of Medicine\u2019s Heart Institute (Incor). He trained in physiology and pharmacology at the Uniformed Services University of the Health Sciences under the mentorship of Robert Goldstein from 1984 to 1987. In 1992, he returned to the University of S\u00e3o Paulo School of Medicine, where he earned his PhD investigating the mechanisms of redox signaling in the vascular system under the supervision of Prot\u00e1sio da Luz. In 2001, with da Luz, Laurindo started the Vascular Biology Laboratory at the Heart Institute (Incor) and became its director in 2008. He investigates the mechanisms and regulatory processes underlying oxidant species production in vascular cells and tissues and their physiological implications for vessel remodeling in disease. His research group uncovered the shear stress-dependent generation of superoxide radical from the endothelium, characterized the redox response to vascular injury, and discovered how the endoplasmic reticulum chaperone protein, disulfide isomerase, interacts functionally and physically with oxidant-generating NADPH oxidase complexes. These findings have led to a better understanding of endoplasmic reticulum pathophysiology on NADPH oxidase function and how redox processes regulate cell migration and vascular remodeling.<\/p>\n","protected":false},"excerpt":{"rendered":"

  More information on speaker\u00a0 Francisco Laurindo is pioneer in redox signaling and cardiovascular biology. He earned his medical degree from the University of S\u00e3o Paulo School of Medicine in 1978 and completed his residence training in internal medicine and cardiology at the University of S\u00e3o Paulo School of Medicine\u2019s Heart Institute (Incor). He trained … Read more<\/a><\/p>\n","protected":false},"author":77299,"featured_media":0,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","_links_to":"","_links_to_target":""},"tags":[90,89,91,92],"tribe_events_cat":[85],"class_list":["post-13926","tribe_events","type-tribe_events","status-publish","hentry","tag-cardiac","tag-cardiovascular","tag-heart","tag-redox","tribe_events_cat-invited-speaker-seminar-series","cat_invited-speaker-seminar-series","odd"],"acf":[],"yoast_head":"\nFall 2024 Seminar Series - 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