{"id":1539,"date":"2022-02-21T09:48:28","date_gmt":"2022-02-21T14:48:28","guid":{"rendered":"https:\/\/www.med.unc.edu\/cemalb\/?page_id=1539"},"modified":"2024-11-27T18:10:36","modified_gmt":"2024-11-27T23:10:36","slug":"rager-lab","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cemalb\/rager-lab\/","title":{"rendered":"Rager Lab"},"content":{"rendered":"

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Julia E. Rager, PhD, MSEE<\/strong><\/h4>\n

Julia Rager is an Assistant Professor in the Department of Environmental Sciences and Engineering (ESE) at the University of North Carolina (UNC)\u2019s Gillings School of Global Public Health.<\/span><\/span>\u00a0<\/span><\/p>\n

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Research Interests<\/h2>\n

The overarching goal of our research is to unravel relationships between environmental exposures and health outcomes, with a focus on complex mixtures at growing prevalence in the environment. We uniquely address this goal by coupling advanced in silico methods with molecular toxicology approaches to evaluate environmental mixtures. Major themes of our current research include the following:<\/span>\u00a0<\/span><\/p>\n

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  1. Mixtures modeling to identify \u2018bad actors\u2019 in the atmosphere.<\/span>\u00a0<\/span><\/li>\n
  2. Evaluating extracellular vesicles as novel mediators of human disease<\/span>\u00a0<\/span><\/li>\n
  3. Translating exposure science and toxicology into risk assessment and policy decision making.<\/span>\u00a0<\/span><\/li>\n
  4. Developing and disseminating training for computational research in environmental health<\/span>\u00a0<\/span><\/li>\n<\/ol>\n

    For more information surrounding the Rager Lab\u2019s research, team members, and background, please see her team\u2019s <\/span>parent website<\/span><\/b> (link to: <\/span>https:\/\/tarheels.live\/ragerlab\/<\/span><\/a>)<\/span>\u00a0<\/span><\/p>\n

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    Current Lab Personnel<\/h2>\n

    Hadley Hartwell, MS, Laboratory Manager<\/span><\/span>\u00a0<\/span>
    \nKyle <\/span>Roell<\/span>, PhD, Data Analyst and Project Manager<\/span><\/span>\u00a0<\/span>
    \nAlexis Payton, MS, Research Data Analyst<\/span><\/span>\u00a0<\/span>
    \nCeleste Carberry, PhD, Research Program Manager<\/span><\/span>\u00a0<\/span><\/p>\n

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    Post-Doctoral Fellows\u00a0<\/span>
    \nElise Hickman, PhD, Postdoctoral Research<\/span>\u00a0<\/span>
    \nJessie Chappel, PhD, Postdoctoral Research<\/span>\u00a0<\/span><\/p>\n

    Doctoral Trainees\u00a0<\/span>
    \nLauren Koval, Graduate Student<\/span>\u00a0<\/span>
    \nSarah Miller, Graduate Student<\/span>\u00a0<\/span>
    \nChloe Chou, Graduate Student<\/span>\u00a0<\/span>
    \nAllison Spring, Graduate Student<\/span>\u00a0<\/span><\/p>\n

    Undergraduate Students<\/span>\u00a0<\/span>
    \nVictoria Carberry, Undergraduate Student<\/span>\u00a0<\/span>
    \nEllie Jiang, Undergraduate Student<\/span>\u00a0<\/span>
    \nKai Malone, Undergraduate Student<\/span>\u00a0<\/span>
    \nRaquel Winker, Undergraduate Student<\/span>\u00a0<\/span><\/p>\n

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    Lab Alumni<\/b>\u00a0<\/span><\/p>\n

    PhD Students<\/span>
    \nCeleste Carberry, PhD 2024<\/span>\u00a0<\/span><\/p>\n

    Masters Students<\/span>\u00a0<\/span>
    \nElena McDermott, MSPH 2023<\/span>\u00a0<\/span>
    \nAlexis Payton, MS 2021<\/span>\u00a0<\/span><\/p>\n

    Undergraduate Students<\/span>\u00a0<\/span>
    \nLauren Simendinger, 2023<\/span>\u00a0<\/span>
    \nDeepak Keshava, 2022<\/span>\u00a0<\/span>
    \nToby Turla, 2021<\/span>\u00a0<\/span>
    \nAlexis Payton, 2022<\/span>\u00a0<\/span>
    \nCeleste Carbery, 2020<\/span>\u00a0<\/span><\/p>\n

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    Publications<\/h2>\n

    To see a complete list of Dr. Julia E. Rager\u2019s publications, see her <\/span>Google Scholar<\/span><\/b> (link:<\/span> https:\/\/scholar.google.com\/citations?user=CUX9888AAAAJ&hl=en<\/span><\/a>)\u00a0 or <\/span>PubMed listing<\/span><\/b> (link: <\/span>https:\/\/www.ncbi.nlm.nih.gov\/sites\/myncbi\/julia.rager.1\/bibliography\/56375750\/public\/?sortby=pubDate&sdirection=descending<\/span><\/a>)<\/span>\u00a0<\/span><\/p>\n

    Example key publications relevant to CEMALB initiatives include the following:<\/span>\u00a0<\/span><\/p>\n

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    1. Winker R*, Payton A<\/span>#<\/span>, Brown E, McDermott E*, Freedman JH, Lenhardt C, Eaves LE, Fry RC, <\/span>Rager JE<\/b>++<\/b><\/span>. Wildfires and Climate Justice: Future Wildfire Events Predicted to Disproportionally Impact Socioeconomically Vulnerable Communities in North Carolina. <\/span>Front Public Health. <\/span><\/i>2024 Apr 29;12:1339700. doi: 10.3389\/fpubh.2024.1339700. PMID: 38741908; PMCID: PMC11089107.<\/span>\u00a0<\/span><\/li>\n
    2. Vitucci E, Carberry CK*, Payton A<\/span>#<\/span>, Herring LE, Mordant AL, McCullough SD, <\/span>Rager JE<\/b>++<\/b><\/span>. Characterizing the Extracellular Vesicle Proteomic Landscape of the Human Airway Using In Vitro Organotypic Multi-Cellular Models. <\/span>Cell – iScience<\/span><\/i>. 2023 Oct 10;26(11):108162. doi: 10.1016\/ j.isci.2023.108162. PMID: 37920665. PMCID: PMC10618692.<\/span>\u00a0<\/span><\/li>\n
    3. Payton A<\/span>#<\/span>, Roell KR, Rebuli ME, Valdar W, Jaspers I, <\/span>Rager JE<\/b>++<\/b><\/span>. Navigating the bridge between wet and dry lab toxicology research to address current challenges with high-dimensional data. <\/span>Front Toxicol. <\/span><\/i>2023 May 26:5:1171175. doi: 10.3389\/ftox.2023.1171175. PMID: 37304253; PMCID: PMC10250703<\/span>\u00a0<\/span><\/li>\n
    4. Carberry CK*, <\/span>Rager JE<\/b>++<\/b><\/span>. The Impact of Environmental Contaminants on Extracellular Vesicles and their Key Molecular Regulators: A Literature and Database-Driven Review. <\/span>Environ Mol Mutagen<\/span><\/i>. 2023 Jan;64(1):50-66. doi: 10.1002\/em.22522. PMID: 36502378. PMCID: PMC10798145.<\/span>\u00a0<\/span><\/li>\n
    5. Kim YH, <\/span>Rager JE<\/b><\/span>, Jaspers I, Gilmour MI. Computational Approach to Link Chemicals in Anthropogenic Smoke Particulate Matter with Toxicity. <\/span>Chem Res Toxicol<\/span><\/i>. 2022 Dec 19;35(12):2210-2213. doi: 10.1021\/acs.chemrestox.2c00270. PMID: 36373932.<\/span>\u00a0<\/span><\/li>\n
    6. Koval LE*, Carberry CK*, Kim YH, McDermott E*, Hartwell H, Jaspers I, Gilmour MI, <\/span>Rager JE<\/b>++<\/b><\/span>. Wildfire Variable Toxicity: Identifying Biomass Smoke Exposure Groupings through Transcriptomic Similarity Scoring. <\/span>Environ Sci Technol<\/span><\/i>. 2022 Dec 6;56(23):17131-17142. doi: 10.1021\/acs.est.2c06043. PMID: 36399130. PMCID: PMC10777820.<\/span>\u00a0<\/span><\/li>\n
    7. Carberry CK*, Koval LE*, Payton A<\/span>#<\/span>, Hartwell H, Ho Kim Y, Smith GJ, Reif DM, Jaspers I, Ian Gilmour M, <\/span>Rager JE<\/b>++<\/b><\/span>. Wildfires and extracellular vesicles: Exosomal microRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke. <\/span>Environ Int<\/span><\/i>. 2022 Sep;167:107419. doi: 10.1016\/j.envint.2022.107419. PMID: 35863239; PMCID: PMC9389917.<\/span>\u00a0<\/span><\/li>\n
    8. Carberry CK*, Keshava D*, Payton A#, Smith GJ, <\/span>Rager JE<\/b>++<\/b><\/span>. Approaches to incorporate extracellular vesicles into exposure science, toxicology, and public health research. <\/span>J Expo Sci Environ Epidemiol<\/span><\/i>. 2022 Sep;32(5):647-659. doi: 10.1038\/s41370-022-00417-w. PMID: 35217808; PMCID: PMC9402811.<\/span>\u00a0<\/span><\/li>\n
    9. Roell K<\/span>#<\/span>, Koval LE*, Boyles R, Patlewicz G, Ring C, Rider CV, Ward-Caviness C, Reif DM, Jaspers I, Fry RC, <\/span>Rager JE<\/b>++<\/b><\/span>. Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research. <\/span>Front Toxicol<\/span><\/i>. 2022 Jun 22;4:893924. doi: 10.3389\/ftox.2022.893924. PMID: 35812168; PMCID: PMC9257219.<\/span>\u00a0<\/span><\/li>\n
    10. Rager JE<\/b><\/span>, Clark J, Eaves LA, Avula V, Niehoff NM, Kim YH, Jaspers I, Gilmour MI. Mixtures modeling identifies chemical inducers versus repressors of toxicity associated with wildfire smoke. <\/span>Sci Total Environ<\/span><\/i>. 2021 Jun 25;775:145759. PMID: 33611182. PMCID: PMC8243846.<\/span>\u00a0<\/span><\/li>\n<\/ol>\n

      \u00a0<\/span><\/p>\n

      \"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

      Julia E. Rager, PhD, MSEE Julia Rager is an Assistant Professor in the Department of Environmental Sciences and Engineering (ESE) at the University of North Carolina (UNC)\u2019s Gillings School of Global Public Health.\u00a0       Research Interests The overarching goal of our research is to unravel relationships between environmental exposures and health outcomes, with … Read more<\/a><\/p>\n","protected":false},"author":104895,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1539","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"\nRager Lab | Center for Environmental Medicine, Asthma and Lung Biology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cemalb\/rager-lab\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rager Lab | Center for Environmental Medicine, Asthma and Lung Biology\" \/>\n<meta property=\"og:description\" content=\"Julia E. 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