North Carolina State University
As a veterinarian with a clinical emphasis on surgical gastroenterology in large animals, Dr. Blikslager has been able to develop novel animal models of intestinal diseases that afflict both people and animals. He has primarily focused on mechanisms of repair in the setting of ischemia/ reperfusion injury, stress-induced gut dysfunction, and experimental inflammatory bowel disease. Additionally, he has used his knowledge of electrophysiology as well as anatomical cellular components of the mucosa to design models that answer basic questions about intestinal mucosal integrity. Much of this research has focused on the role of the tight junction in restitution, with a particular interest in the role of the chloride channel ClC-2 in tight junction re-assembly.