Publications 2013 - 2018

CGIBD Members bold; P/F recipients underlined.
The publications listed below were made possible, in part, by use of CGIBD cores.
Publication Information
Zwarycz B, Gracz AD, Rivera KR, Williamson IA, Samsa LA, Starmer J, Daniele MA, Salter-Cid L, Zhao Q, Magness ST. IL22 Inhibits epithelial stem cell expansion in an ileal organoid model. Cellular and Molecular Gastroenterology and Hepatology. 2019;7(1):1-17. PMCID: PMC6199238.
Gracz AD, Samsa LA, Fordham MJ, Trotier DC, Zwarycz B, Lo YH, Bao K, Starmer J, Raab JR, Shroyer NF, Reinhardt RL, Magness ST. Sox4 promotes Atoh1-independent intestinal secretory differentiation toward tuft and enteroendocrine fates. Gastroenterology. 2018;155(5):1508-23 e10. PMCID: PMC6232678.
Mazzone CM, Pati D, Michaelides M, DiBerto J, Fox JH, Tipton G, Anderson C, Duffy K, McKlveen JM, Hardaway JA, Magness ST, Falls WA, Hammack SE, McElligott ZA, Hurd YL, Kash TL. Acute engagement of Gq-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior. Mol Psychiatry. 2018;23(1):143-53. PMCID: PMC5468515.
Reese AT, Cho EH, Klitzman B, Nichols SP, Wisniewski NA, Villa MM, Durand HK, Jiang S, Midani FS, Nimmagadda SN, O'Connell TM, Wright JP, Deshusses MA, David LA. Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. Elife. 2018;7. PMCID: PMC6008055.
Smith NR, Swain JR, Davies PS, Gallagher AC, Parappilly MS, Beach CZ, Streeter PR, Williamson IA, Magness ST, Wong MH. Monoclonal antibodies reveal dynamic plasticity between Lgr5- and Bmi1-expressing intestinal cell populations. Cellular and Molecular Gastroenterology and Hepatology. 2018;6(1):79-96. PMCID: PMC6008251.
Williamson IA, Arnold JW, Samsa LA, Gaynor L, DiSalvo M, Cocchiaro JL, Carroll I, Azcarate-Peril MA, Rawls JF, Allbritton NL, Magness ST. A High-Throughput organoid microinjection platform to study gastrointestinal microbiota and luminal physiology. Cellular and Molecular Gastroenterology and Hepatology. 2018;6(3):301-19. PMCID: PMC6092482.
Ziegler AL, Freeman CK, Fogle CA, Burke MJ, Davis JL, Cook VL, Southwood LL, Blikslager AT. Multicentre, blinded, randomised clinical trial comparing the use of flunixin meglumine with firocoxib in horses with small intestinal strangulating obstruction. Equine Veterinary Journal. 2018; 8(29). PMID: 30156312
Pascual F, Schisler JC, Grevengoed TJ, Willis MS, Coleman RA. Modeling the transition from decompensated to pathological hypertrophy. J Am Heart Assoc. 2018;7(8). PMCID: PMC6015423.
Azcarate-Peril MA, Ritter AJ, Savaiano D, Monteagudo-Mera A, Anderson C, Magness ST, Klaenhammer TR. Impact of short-chain galactooligosaccharides on the gut microbiome of lactose-intolerant individuals. Proceedings of the National Academy of Sciences of the United States of America. 2017;114(3):E367-E75. PMCID: PMC5255593.
Kechele DO, Blue RE, Zwarycz B, Espenschied ST, Mah AT, Siegel MB, Perou CM, Ding S, Magness ST, Lund PK, Caron KM. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. The Journal of Clinical Investigation. 2017;127(2):593-607. PMCID: PMC5272174.
Peck BC, Mah AT, Pitman WA, Ding S, Lund PK, Sethupathy P. Functional transcriptomics in diverse intestinal epithelial cell types reveals robust MicroRNA sensitivity in intestinal stem cells to microbial status. The Journal of Biological Chemistry. 2017;292(7):2586-600. PMCID: PMC5314158.
Attayek PJ, Ahmad AA, Wang Y, Williamson I, Sims CE, Magness ST, Allbritton NL. In vitro polarization of colonoids to create an intestinal stem cell compartment. PLOS One. 2016;11(4):e0153795. PMCID: PMC4839657.
Bago JR, Alfonso-Pecchio A, Okolie O, Dumitru R, Rinkenbaugh A, Baldwin AS, Miller CR, Magness ST, Hingtgen SD. Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma. Nature Communications. 2016;7:10593. PMCID: PMC4740908.
Dellon ES, Higgins LL, Beitia R, Rusin S, Woosley JT, Veerappan R, Selitsky SR, Parker JS, Genta RM, Lash RH, Aranda R, Peach RJ, Grimm M. Prospective assessment of serum periostin as a biomarker for diagnosis and monitoring of eosinophilic oesophagitis. Alimentary Pharmacology & Therapeutics. 2016;44(2):189-97. PMCID: PMC4907797.
Samsa LA, Fleming N, Magness S, Qian L, Liu J. Isolation and Characterization of Single Cells from Zebrafish Embryos. Journal of Visualized Experiments : JoVE. 2016(109). PMCID: PMC4828977.
Dellon ES, Rusin S, Gebhart JH, Covey S, Higgins LL, Beitia R, Speck O, Woodward K, Woosley JT, Shaheen NJ. Utility of a noninvasive serum biomarker panel for diagnosis and monitoring of Eosinophilic Esophagitis: a prospective study. The American Journal of Gastroenterology. 2015;110(6):821-7. PMCID: PMC4578703
Gracz AD, Williamson IA, Roche KC, Johnston MJ, Wang F, Wang Y, Attayek PJ, Balowski J, Liu XF, Laurenza RJ, Gaynor LT, Sims CE, Galanko JA, Li L, Allbritton NL, Magness ST. A high-throughput platform for stem cell niche co-cultures and downstream gene expression analysis. Nature Cell Biology. 2015;17(3):340-9. PMCID: PMC4405128.
Roche KC, Gracz AD, Liu XF, Newton V, Akiyama H, Magness ST. SOX9 maintains reserve stem cells and preserves radioresistance in mouse small intestine. Gastroenterology. 2015;149(6):1553-63 e10. PMCID: PMC4709179.
Santoro MA, Blue RE, Andres SF, Mah AT, Van Landeghem L, Lund PK. Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF1 receptor, affect radiation-induced apoptosis in colon. American Journal of Physiology Gastrointestinal and Liver Physiology. 2015:ajpgi.00189.2015. PMCID: PMC4593818
Seiler KM, Schenhals EL, von Furstenberg RJ, Allena BK, Smith BJ, Scaria D, Bresler MN, Dekaney CM, Henning SJ. Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage. Cell and Tissue Research. 2015;361(2):427-38. : PMC4530061.
Van Landeghem L, Santoro MA, Mah AT, Krebs AE, Dehmer JJ, McNaughton KK, Helmrath MA, Magness ST, Lund PK. IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2015;29(7):2828-42. PMCID: PMC4478798.
Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Muhlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, Ramsden DA, Davis BK, Ting JP. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nature Medicine. 2015;21(8):906-13. PMCID: PMC4529369.
Gach PC, Attayek PJ, Whittlesey RL, Yeh JJ, Allbritton NL. Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma. Biosensors & Bioelectronics. 2014;54:476-83. PMCID: PMC3947965.
Gracz AD, Magness ST. Defining hierarchies of stemness in the intestine: evidence from biomarkers and regulatory pathways. American Journal of Physiology Gastrointestinal and Liver Physiology. 2014;307(3):G260-73. PMCID: PMC4121637.
Mah AT, Van Landeghem L, Gavin HE, Magness ST, Lund PK. Impact of diet-induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1. Endocrinology. 2014;155(9):en20141112. PMCID: PMC4138564.
Proctor A, Herrera-Loeza SG, Wang Q, Lawrence DS, Yeh JJ, Allbritton NL. Measurement of protein kinase B activity in single primary human pancreatic cancer cells. Analytical Chemistry. 2014;86(9):4573-80. PMCID: PMC4018172.
Santoro MA, Andres SF, Galanko JA, Sandler RS, Keku TO, Lund PK. Reduced insulin-like growth factor 1 receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk. Cancer Epidemiology, Biomarkers & Prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2014;23(10):2093-100. : PMC4201381.
Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE. Innate PI3K p110delta regulates Th1/Th17 development and microbiota-dependent colitis. Journal of Immunology. 2014;192(8):3958-68. PMCID: PMC3992276.
Sun X, Jobin C. Nucleotide-binding oligomerization domain-containing protein 2 controls host response to Campylobacter jejuni in Il10-/- mice. The Journal of Infectious Diseases. 2014;210(7):1145-54. : PMC4168300.
Wang Y, Ahmad AA, Sims CE, Magness ST, Allbritton NL. In vitro generation of colonic epithelium from primary cells guided by microstructures. Lab on a Chip. 2014;14(9):1622-31. PMCID: PMC4037563.
Ananthakrishnan AN, Martin C, Kane S, Sandler RS, Long MD. Paternal disease activity is associated with difficulty in conception among men with inflammatory bowel diseases. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2019;17(1):203-4. PMCID: PMC6181789.
Peery AF, Crockett SD, Murphy CC, Lund JL, Dellon ES, Williams JL, Jensen ET, Shaheen NJ, Barritt AS, Lieber SR, Kochar B, Barnes EL, Fan YC, Pate V, Galanko J, Baron TH, Sandler RS. Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: Update 2018. Gastroenterology. 2019;156(1):254-72 e11. PMID: 30315778
Busch EL, Don PK, Chu H, Richardson DB, Keku TO, Eberhard DA, Avery CL, Sandler RS. Diagnostic accuracy and prediction increment of markers of epithelial-mesenchymal transition to assess cancer cell detachment from primary tumors. BMC Cancer. 2018;18(1):82. PMCID: PMC5769498.
Busch EL, Galanko JA, Sandler RS, Goel A, Keku TO. Lifestyle factors, colorectal tumor methylation, and aurvival among African Americans and European Americans. Scientific Reports. 2018;8(1):9470. PMCID: PMC6013500.
Dorn SD, Cirri HO, Chang AO, Crockett SD, Galanko JA, Baron JA. An integrated electronic health record-based workflow to improve management of colonoscopy-generated pathology results. Clin Exp Gastroenterol. 2018;11:391-7. PMCID: PMC6181114.
Egberg MD, Galanko JA, Barnes EL, Kappelman MD. Thrombotic and infectious risks of parenteral nutrition in hospitalized pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 2018;(10) PMID: 30304444
Egberg MD, Mitchell PD, Galanko JA, Rufo PA. Effectiveness of oral iron supplementation in treatment of anemia associated with pediatric ulcerative colitis flare. American Journal of Hematology. 2018;93(12):E404-e6. PMCID: PMC6260819.
Eluri S, Cross RK, Martin C, Weinfurt KP, Flynn KE, Long MD, Chen W, Anton K, Sandler RS, Kappelman MD. Inflammatory bowel diseases can adversely impact domains of sexual function such as satisfaction with sex life. Digestive Diseases and Sciences. 2018;63(6):1572-82. PMCID: PMC5955825.
Eluri S, Selitsky SR, Perjar I, Hollyfield J, Betancourt R, Randall C, Rusin S, Woosley JT, Shaheen NJ, Dellon ES. Clinical and molecular factors associated with histologic response to topical steroid treatment in patients sith Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology: the official clinical practice journal of the American Gastroenterological Association. 2018;(10). PMCID: 30213583.
Evon DM, Amador J, Stewart P, Reeve BB, Lok AS, Sterling RK, Di Bisceglie AM, Reau N, Serper M, Sarkar S, Lim JK, Golin CE, Fried MW. Psychometric properties of the PROMIS short form measures in a U.S. cohort of 961 patients with chronic hepatitis C prescribed direct acting antiviral therapy. Alimentary Pharmacology & Therapeutics. 2018;47(7):1001-11. PMCID: PMC5842131.
Evon DM, Golin CE, Ruffin R, Ayres S, Fried MW. Novel patient-reported outcomes (PROs) used in a pilot and feasibility study of a cognitive behavioral coping skills (CBCS) group intervention for patients with chronic hepatitis C. Pilot Feasibility Stud. 2018;4:92. PMCID: PMC6020443.
Evon DM, Stewart PW, Amador J, Serper M, Lok AS, Sterling RK, Sarkar S, Golin CE, Reeve BB, Nelson DR, Reau N, Lim JK, Reddy KR, Di Bisceglie AM, Fried MW. A comprehensive assessment of patient reported symptom burden, medical comorbidities, and functional well being in patients initiating direct acting antiviral therapy for chronic hepatitis C: Results from a large US multi-center observational study. PloS One. 2018;13(8):e0196908. PMCID: PMC6070182
Herfarth H, Barnes EL, Valentine JF, Hanson J, Higgins PDR, Isaacs KL, Jackson S, Osterman MT, Anton K, Ivanova A, Long MD, Martin C, Sandler RS, Abraham B, Cross RK, Dryden G, Fischer M, Harlan W, Levy C, McCabe R, Polyak S, Saha S, Williams E, Yajnik V, Serrano J, Sands BE, Lewis JD. Methotrexate is not superior to placebo in maintaining steroid-free response or remission in ulcerative colitis. Gastroenterology. 2018;155(4):1098-108.e9. PMCID: PMC6174092.
Jones RB, Fodor AA, Peery AF, Tsilimigras MCB, Winglee K, McCoy A, Sioda M, Sandler RS, Keku TO. An aberrant microbiota is not strongly associated with incidental colonic diverticulosis. Scientific Reports. 2018;8(1):4951. PMCID: PMC5862835.
Kerlin AM, Long M, Kappelman M, Martin C, Sandler RS. Profiles of patients who use marijuana for inflammatory bowel disease. Digestive Diseases and Sciences. 2018;63(6):1600-4. PMID: 29594968
Kochar B, Barnes EL, Herfarth HH, Martin CF, Ananthakrishnan AN, McGovern D, Long M, Sandler RS. Asians have more perianal Crohn disease and ocular manifestations compared with white Americans. Inflamm Intest Dis. 2018;2(3):147-53. PMCID: PMC5986188.
Kochar B, Barnes EL, Long MD, Cushing KC, Galanko J, Martin CF, Raffals LE, Sandler RS. Depression is associated with more aggressive inflammatory bowel disease. The American Journal of Gastroenterology. 2018;113(1):80-5. PMCID: PMC5962285.
Kochar B, Barnes EL, Peery AF, Cools KS, Galanko J, Koruda M, Herfarth HH. Delayed Ileal Pouch Anal Anastomosis has a lower 30-day adverse event rate: analysis from the National Surgical Quality Improvement Program. Inflammatory Bowel Diseases. 2018;24(8):1833-9. PMID: 29697787
Koutlas NT, Eluri S, Rusin S, Perjar I, Hollyfield J, Woosley JT, Shaheen NJ, Dellon ES. Impact of smoking, alcohol consumption, and NSAID use on risk for and phenotypes of eosinophilic esophagitis. Diseases of the Esophagus : official journal of the International Society for Diseases of the Esophagus / ISDE. 2018;31(1):1-7. PMCID: PMC6036648.
Peery AF, Keku TO, Addamo C, McCoy AN, Martin CF, Galanko JA, Sandler RS. Colonic diverticula are not associated with mucosal inflammation or chronic gastrointestinal symptoms. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2018;16(6):884-91.e1. PMCID: PMC5722710.
Peery AF, Shaheen NJ, Cools KS, Baron TH, Koruda M, Galanko JA, Grimm IS. Morbidity and mortality after surgery for nonmalignant colorectal polyps. Gastrointestinal Endoscopy. 2018;87(1):243-50.e2. PMCID: PMC5634910.
Rolston VS, Boroujerdi L, Long MD, McGovern DPB, Chen W, Martin CF, Sandler RS, Carmichael JD, Dubinsky M, Melmed GY. The influence of hormonal fluctuation on inflammatory bowel disease symptom severity-a cross-sectional cohort study. Inflammatory Bowel Diseases. 2018;24(2):387-93. PMID: 29361085
Tappata M, Eluri S, Perjar I, Hollyfield J, Betancourt R, Randall C, Woosley JT, Wechsler JB, Dellon ES. Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy. 2018;73(10):2088-92. PMCID: PMC6207454.
Abdalla MI, Sandler RS, Kappelman MD, Martin CF, Chen W, Anton K, Long MD. Prevalence and impact of inflammatory bowel disease-Irritable Bowel Syndrome on patient-reported outcomes in CCFA Partners. Inflammatory Bowel Diseases. 2017;23(2):325-31. PMID: 28092305
Ananthakrishnan AN, Sakuraba A, Barnes EL, Pekow J, Raffals L, Long MD, Sandler RS. The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease. Alimentary Pharmacology & Therapeutics. 2017;46(2):162-8. PMCID: PMC5484085.
Asher GN, Xie Y, Moaddel R, Sanghvi M, Dossou KS, Kashuba AD, Sandler RS, Hawke RL. Randomized pharmacokinetic crossover study comparing 2 curcumin preparations in plasma and rectal tissue of healthy human volunteers. Journal of Clinical Pharmacology. 2017;57(2):185-93. PMCID: PMC5233601.
Barnes EL, Herfarth HH, Sandler RS, Chen W, Jaeger E, Nguyen VM, Robb AR, Kappelman MD, Martin CF, Long MD. Pouch-related symptoms and quality of life in patients with Ileal Pouch-Anal Anastomosis. Inflammatory Bowel Diseases. 2017;23(7):1218-24. PMCID: PMC5512700.
Barnes EL, Kochar B, Long MD, Kappelman MD, Martin CF, Korzenik JR, Crockett SD. Modifiable risk factors for hospital readmission among patients with inflammatory bowel disease in a nationwide eatabase. Inflammatory Bowel Diseases. 2017;23(6):875-81. PMCID: PMC5512697.
Barnes EL, Kochar B, Long MD, Martin CF, Crockett SD, Korzenik JR, Kappelman MD. The burden of hospital readmissions among pediatric patients with inflammatory bowel disease. The Journal of Pediatrics. 2017;191:184-9 e1. PMCID: PMC5792080.
Cheong J, Galanko JA, Arora S, Cabezas J, Ndugga NJ, Lucey MR, Hayashi PH, Barritt AS, Bataller R. Reduced impact of renal failure on the outcome of patients with alcoholic liver disease undergoing liver transplantation. Liver International : official journal of the International Association for the Study of the Liver. 2017;37(2):290-8. PMCID: PMC5136341.
Evon DM, Golin CE, Stoica T, Jones RE, Willis SJ, Galanko J, Fried MW. What's important to the patient? Informational needs of patients making decisions about Hepatitis C Treatment. Patient. 2017;10(3):335-44. PMCID: PMC5597439.
Fedirko V, McKeown-Eyssen G, Serhan CN, Barry EL, Sandler RS, Figueiredo JC, Ahnen DJ, Bresalier RS, Robertson DJ, Anderson CW, Baron JA. Plasma lipoxin A4 and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas. Mol Carcinog. 2017;56(8):1977-83. PMCID: PMC5496792.
Huang MC, Douillet C, Su M, Zhou K, Wu T, Chen W, Galanko JA, Drobna Z, Saunders RJ, Martin E, Fry RC, Jia W, Styblo M. Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure. Arch Toxicol. 2017;91(1):189-202. PMCID: PMC4987274.
Kochar B, Long MD, Galanko J, Raffals LE, Ananthakrishnan A, Sandler RS. Inflammatory bowel disease is similar in patients with older onset and younger onset. Inflammatory Bowel Diseases. 2017;23(7):1187-94. PMCID: PMC5469700.
Kochar B, Long MD, Shelton E, Young L, Farraye FA, Yajnik V, Herfarth H. Safety and efficacy of Teduglutide (Gattex) in patients with Crohn's Disease and need for parenteral support due to short bowel syndrome-associated intestinal failure. Journal of Clinical Gastroenterology. 2017;51(6):508-11. PMCID: PMC5243925.
Reed CC, Wolf WA, Cotton CC, Dellon ES. A visual analogue scale and a Likert scale are simple and responsive tools for assessing dysphagia in eosinophilic oesophagitis. Alimentary Pharmacology & Therapeutics. 2017;45(11):1443-8. PMCID: PMC5419874.
Ren NS, Ji M, Tokar EJ, Busch EL, Xu X, Lewis D, Li X, Jin A, Zhang Y, Wu WK, Huang W, Li L, Fargo DC, Keku TO, Sandler RS, Li X. Haploinsufficiency of SIRT1 enhances glutamine metabolism and promotes cancer development. Curr Biol. 2017;27(4):483-94. PMCID: PMC5319916.
Wolf WA, Piazza NA, Gebhart JH, Rusin S, Covey S, Higgins LL, Beitia R, Speck O, Woodward K, Cotton CC, Runge TM, Eluri S, Woosley JT, Shaheen NJ, Dellon ES. Association between body mass index and clinical and endoscopic features of eosinophilic esophagitis. Digestive Diseases and Sciences. 2017;62(1):143-9. PMCID: PMC5218962.
Abdalla MI, Sandler RS, Kappelman MD, Martin CF, Chen W, Anton K, Long MD. The impact of ostomy on quality of life and functional status of Crohn's Disease Patients. Inflammatory Bowel Diseases. 2016;22(11):2658-64. PMCID: PMC5087602.
Arvanitis M, DeWalt DA, Martin CF, Long MD, Chen W, Jaeger B, Sandler RS, Kappelman MD. Patient-reported outcomes measurement information system in children with Crohn's Disease. The Journal of Pediatrics. 2016;174:153-9.e2. PMCID: PMC5157125.
Brotherton CS, Martin CA, Long MD, Kappelman MD, Sandler RS. Avoidance of fiber is associated with greater risk of Crohn's Disease flare in a 6-month period. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016;14(8):1130-6. PMCID: PMC4930425.
Busch EL, Keku TO, Richardson DB, Cohen SM, Eberhard DA, Avery CL, Sandler RS. Evaluating markers of epithelial-mesenchymal transition to identify cancer patients at risk for metastatic disease. Clin Exp Metastasis. 2016;33(1):53-62. PMCID: PMC4742430.
Chung AE, Sandler RS, Long MD, Ahrens S, Burris JL, Martin CF, Anton K, Robb A, Caruso TP, Jaeger EL, Chen W, Clark M, Myers K, Dobes A, Kappelman MD. Harnessing person-generated health data to accelerate patient-centered outcomes research: the Crohn's and Colitis Foundation of America PCORnet Patient Powered Research Network (CCFA Partners). J Am Med Inform Assoc. 2016;23(3):485-90. PMCID: PMC4901381.
Cotton CC, Baird D, Sandler RS, Long MD. Hormonal contraception use is common among patients with inflammatory bowel diseases and an elevated risk of deep vein thrombosis. Inflammatory Bowel Diseases. 2016;22(7):1631-8. PMCID: PMC5064836.
Cozzo AJ, Sundaram S, Zattra O, Qin Y, Freemerman AJ, Essaid L, Darr DB, Montgomery SA, McNaughton KK, Ezzell JA, Galanko JA, Troester MA, Makowski L. cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer. Springerplus. 2016;5:348. PMCID: PMC4799044.
Crockett SD, Cirri HO, Kelapure R, Galanko JA, Martin CF, Dellon ES. Use of an abdominal compression device in colonoscopy: a randomized, sham-controlled trial. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016;14(6):850-7 e3. PMCID: PMC4875866.
Gaines LS, Slaughter JC, Horst SN, Schwartz DA, Beaulieu DB, Haman KL, Wang L, Martin CF, Long MD, Sandler RS, Kappelman MD. Association between affective-cognitive symptoms of depression and exacerbation of Crohn's Disease. The American Journal of Gastroenterology. 2016;111(6):864-70. PMCID: PMC4965803.
Geisz M, Ha C, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS, Long MD. Medication utilization and the impact of continued corticosteroid use on patient-reported outcomes in older patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 2016;22(6):1435-41. PMCID: PMC4868778.
Hod K, Ringel-Kulka T, Martin CF, Maharshak N, Ringel Y. High-sensitive C-reactive protein as a marker for inflammation in Irritable Bowel Syndrome. Journal of Clinical Gastroenterology. 2016;50(3):227-32. PMCID: PMC4950940.
Jensen ET, Martin CF, Kappelman MD, Dellon ES. Prevalence of Eosinophilic Gastritis, Gastroenteritis, and Colitis: Estimates from a national administrative database. Journal of Pediatric Gastroenterology and Nutrition. 2016;62(1):36-42. PMCID: PMC4654708.
Johnson AR, Qin Y, Cozzo AJ, Freemerman AJ, Huang MJ, Zhao L, Sampey BP, Milner JJ, Beck MA, Damania B, Rashid N, Galanko JA, Lee DP, Edin ML, Zeldin DC, Fueger PT, Dietz B, Stahl A, Wu Y, Mohlke KL, Makowski L. Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation. Mol Metab. 2016;5(7):506-26. PMCID: PMC4921943.
Kochar B, Aldridge M, Cook SF, Bright R, Mallette M, Moniz H, Shah SA, LeLeiko NS, Shapiro J, Sands BE, Chen W, Jaeger E, Galanko J, Long MD, Martin CF, Sandler RS, Kappelman MD. Achieving synergy: linking an internet-based inflammatory bowel disease cohort to a community-based inception cohort and multicentered cohort in inflammatory bowel disease. J Med Internet Res. 2016;18(6):e124. PMCID: PMC4912687.
Lewis CM, Wolf WA, Xun P, Sandler RS, He K. Racial differences in dietary changes and quality of life after a colorectal cancer diagnosis: a follow-up of the study of outcomes in colorectal cancer survivors cohort. The American Journal of Clinical Nutrition. 2016;103(6):1523-30. PMCID: PMC4880997.
Li N, Pasricha S, Bulsiewicz WJ, Pruitt RE, Komanduri S, Wolfsen HC, Chmielewski GW, Corbett FS, Chang KJ, Shaheen NJ. Effects of preceding endoscopic mucosal resection on the efficacy and safety of radiofrequency ablation for treatment of Barrett's esophagus: results from the United States Radiofrequency Ablation Registry. Diseases of the Esophagus : official journal of the International Society for Diseases of the Esophagus / ISDE. 2016;29(6):537-43. PMCID: PMC4977202.
Long MD, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS. Role of nonsteroidal anti-inflammatory drugs in exacerbations of inflammatory bowel disease. Journal of Clinical Gastroenterology. 2016;50(2):152-6. PMCID: PMC4703528.
Murphy CC, Sandler RS, Grubber JM, Johnson MR, Fisher DA. Underuse and overuse of colonoscopy for repeat screening and surveillance in the Veterans Health Administration. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016;14(3):436-44 e1. PMCID: PMC4761454.
Peery AF, Keku TO, Martin CF, Eluri S, Runge T, Galanko JA, Sandler RS. Distribution and characteristics of colonic diverticula in a United States screening population. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016;14(7):980-5.e1. PMCID: PMC4912930.
Qin Y, Sundaram S, Essaid L, Chen X, Miller SM, Yan F, Darr DB, Galanko JA, Montgomery SA, Major MB, Johnson GL, Troester MA, Makowski L. Weight loss reduces basal-like breast cancer through kinome reprogramming. Cancer Cell Int. 2016;16:26. PMCID: PMC4818517.
Randell RL, Gulati AS, Cook SF, Martin CF, Chen W, Jaeger EL, Schoenborn AA, Basta PV, Dejong H, Luo J, Gallant M, Sandler RS, Long MD, Kappelman MD. Collecting biospecimens from an internet-based prospective cohort study of inflammatory bowel disease (CCFA Partners): A Feasibility Study. JMIR Res Protoc. 2016;5(1):e3. PMCID: PMC4719077.
Weaver KN, Kappelman MD, Sandler RS, Martin CF, Chen W, Anton K, Long MD. Variation in care of inflammatory bowel diseases patients in Crohn's and Colitis Foundation of America Partners: role of gastroenterologist practice setting in disease outcomes and quality process measures. Inflammatory Bowel Diseases. 2016;22(11):2672-7. PMCID: PMC5278899.
Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS. Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2015;13(6):1197-200. PMCID: PMC4440845.
Busch EL, Martin C, DeWalt DA, Sandler RS. Functional health literacy, chemotherapy decisions, and outcomes among a colorectal cancer cohort. Cancer Control : journal of the Moffitt Cancer Center. 2015;22(1):95-101. PMCID: PMC4578694.
Cotton CC, Duits LC, Wolf WA, Peery AF, Dellon ES, Bergman JJ, Shaheen NJ. Spatial predisposition of dysplasia in Barrett's esophagus segments: a pooled analysis of the SURF and AIM dysplasia trials. The American Journal of Gastroenterology. 2015;110(10):1412-9. PMCID: PMC4785998.
Cotton CC, Wolf WA, Pasricha S, Li N, Madanick RD, Spacek MB, Ferrell K, Dellon ES, Shaheen NJ. Recurrent intestinal metaplasia after radiofrequency ablation for Barrett's esophagus: endoscopic findings and anatomic location. Gastrointestinal Endoscopy. 2015;81(6):1362-9. PMCID: PMC4439393.
Dellon ES, Erichsen R, Baron JA, Shaheen NJ, Vyberg M, Sorensen HT, Pedersen L. The increasing incidence and prevalence of eosinophilic oesophagitis outpaces changes in endoscopic and biopsy practice: national population-based estimates from Denmark. Alimentary Pharmacology & Therapeutics. 2015;41(7):662-70. : PMC4504237.
Figueiredo JC, Crockett SD, Snover DC, Morris CB, McKeown-Eyssen G, Sandler RS, Ahnen DJ, Robertson DJ, Burke CA, Bresalier RS, Church JM, Church TR, Baron JA. Smoking-associated risks of conventional adenomas and serrated polyps in the colorectum. Cancer Causes & Control : CCC. 2015;26(3):377-86. PMCID: PMC4331601.
Jensen ET, Kappelman MD, Martin CF, Dellon ES. Health-care utilization, costs, and the burden of disease related to eosinophilic esophagitis in the United States. The American Journal of Gastroenterology. 2015;110(5):626-32. PMCID: PMC4590991.
Jones PD, Kappelman MD, Martin CF, Chen W, Sandler RS, Long MD. Exercise decreases risk of future active disease in patients with inflammatory bowel disease in remission. Inflammatory Bowel Diseases. 2015;21(5):1063-71. PMCID: PMC4402239.
Long MD, Cadigan RJ, Cook SF, Haldeman K, Kuczynski K, Sandler RS, Martin CF, Chen W, Kappelman MD. Perceptions of patients with inflammatory bowel diseases on biobanking. Inflammatory Bowel Diseases. 2015;21(1):132-8. PMCID: PMC4573563.
Mack CD, Brookhart MA, Glynn RJ, Meyer AM, Carpenter WR, Sandler RS, Sturmer T. Comparative effectiveness of Oxaliplatin versus 5-flourouricil in older adults: an instrumental variable analysis. Epidemiology. 2015;26(5):690-9. PMCID: PMC4906444.
Murphy CC, Lewis CL, Golin CE, Sandler RS. Underuse of surveillance colonoscopy in patients at increased risk of colorectal cancer. The American Journal of Gastroenterology. 2015;110(5):633-41. PMCID: PMC4422764.
Murphy CC, Martin CF, Sandler RS. Racial differences in obesity measures and risk of colorectal adenomas in a large screening population. Nutrition and Cancer. 2015;67(1):98-104. PMCID: PMC4281505
Pasricha S, Cotton C, Hathorn KE, Li N, Bulsiewicz WJ, Wolf WA, Muthusamy VR, Komanduri S, Wolfsen HC, Pruitt RE, Ertan A, Chmielewski GW, Shaheen NJ. Effects of learning curve on efficacy of radiofrequency ablation for Barrett's esophagus. Gastroenterology. 2015. PMCID: PMC4584171
Pasricha S, Li N, Bulsiewicz WJ, Rothstein RI, Infantolino A, Ertan A, Camara DS, Dellon ES, Triadafilopoulos G, Lightdale CJ, Madanick RD, Lyday WD, Muthusamy RV, Overholt BF, Shaheen NJ. Sex and race and/or ethnicity differences in patients undergoing radiofrequency ablation for Barrett's esophagus: results from the U.S. RFA Registry. Gastrointestinal Endoscopy. 2015;82(2):276-84. PMCID: PMC4506693
Peck BC, Weiser M, Lee SE, Gipson GR, Iyer VB, Sartor RB, Herfarth HH, Long MD, Hansen JJ, Isaacs KL, Trembath DG, Rahbar R, Sadiq TS, Furey TS, Sethupathy P, Sheikh SZ. MicroRNAs classify different disease behavior phenotypes of Crohn's Disease and may have prognostic utility. Inflammatory Bowel Diseases. 2015;21(9):2178-87. PMCID: PMC4603665.
Peery AF, Martin CF, Levinson SE, Sandler RS. Colonic diverticula are not associated with an increased risk of colorectal adenomas. The American Journal of Gastroenterology. 2015;110(12):1694-7. PMCID: PMC4765899.
Peery AF, Sandler RS, Galanko JA, Bresalier RS, Figueiredo JC, Ahnen DJ, Barry EL, Baron JA. Risk Factors for hemorrhoids on screening colonoscopy. PloS One. 2015;10(9):e0139100. PMCID: PMC4583402.
Ringel-Kulka T, Choi CH, Temas D, Kim A, Maier DM, Scott K, Galanko JA, Ringel Y. Altered colonic bacterial rermentation as a potential pathophysiological factor in irritable bowel syndrome. The American Journal of Gastroenterology. 2015;110(9):1339-46. PMCID: PMC4983766.
Wang H, Iwasaki M, Haiman CA, Kono S, Wilkens LR, Keku TO, Berndt SI, Tsugane S, Le Marchand L. Interaction between Red Meat Intake and NAT2 Genotype in Increasing the Risk of Colorectal Cancer in Japanese and African Americans. PloS One. 2015;10(12):e0144955. PMCID: PMC4684304.
Wolf WA, Cotton CC, Green DJ, Hughes JT, Woosley JT, Shaheen NJ, Dellon ES. Predictors of response to steroid therapy for eosinophilic esophagitis and treatment of steroid-refractory patients. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2015;13(3):452-8. PMCID: PMC4312270.
Wolf WA, Pasricha S, Cotton C, Li N, Triadafilopoulos G, Muthusamy VR, Chmielewski GW, Corbett FS, Camara DS, Lightdale CJ, Wolfsen H, Chang KJ, Overholt BF, Pruitt RE, Ertan A, Komanduri S, Infantolino A, Rothstein RI, Shaheen NJ. Incidence of esophageal adenocarcinoma and causes of mortality after radiofrequency ablation of Barrett's esophagus. Gastroenterology. 2015;149(7):1752-61.e1. PMCID: PMC4785890.
Carethers JM, Murali B, Yang B, Doctolero RT, Tajima A, Basa R, Smith EJ, Lee M, Janke R, Ngo T, Tejada R, Ji M, Kinseth M, Cabrera BL, Miyai K, Keku TO, Martin CF, Galanko JA, Sandler RS, McGuire KL. Influence of race on microsatellite instability and CD8+ T cell infiltration in colon cancer. PloS One. 2014;9(6):e100461. PMCID: PMC4067325.
Crockett SD, Mott LA, Barry EL, Figueiredo JC, Burke CA, Baxter GJ, Sandler RS, Baron JA. C-reactive protein and risk of colorectal adenomas or serrated polyps: a prospective study. Cancer Prevention Research. 2014;7(11):1122-7. PMCID: PMC4221539.
da Costa KA, Corbin KD, Niculescu MD, Galanko JA, Zeisel SH. Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology. 2014;28(7):2970-8. PMCID: PMC4062831.
Dassopoulos T, Dubinsky MC, Bentsen JL, Martin CF, Galanko JA, Seidman EG, Sandler RS, Hanauer SB. Randomised clinical trial: individualised vs. weight-based dosing of azathioprine in Crohn's disease. Alimentary Pharmacology & Therapeutics. 2014;39(2):163-75. PMCID: PMC3918445.
Dellon ES, Jensen ET, Martin CF, Shaheen NJ, Kappelman MD. Prevalence of eosinophilic esophagitis in the United States. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2014;12(4):589-96.e1. PMCID: PMC3952040.
Herfarth HH, Martin CF, Sandler RS, Kappelman MD, Long MD. Prevalence of a gluten-free diet and improvement of clinical symptoms in patients with inflammatory bowel diseases. Inflammatory Bowel Diseases. 2014;20(7):1194-7. PMCID: PMC4331053
Kappelman MD, Long MD, Martin C, DeWalt DA, Kinneer PM, Chen W, Lewis JD, Sandler RS>. Evaluation of the patient-reported outcomes measurement information system in a large cohort of patients with inflammatory bowel diseases. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2014;12(8):1315-23.e2. PMCID: PMC4361943.
Kupfer SS, Skol AD, Hong E, Ludvik A, Kittles RA, Keku TO, Sandler RS, Ellis NA. Shared and independent colorectal cancer risk alleles in TGFbeta-related genes in African and European Americans. Carcinogenesis. 2014;35(9):2025-30. PMCID: PMC4146413.
Long MD, Hutfless S, Kappelman MD, Khalili H, Kaplan GG, Bernstein CN, Colombel JF, Gower-Rousseau C, Herrinton L, Velayos F, Loftus EV, Jr., Nguyen GC, Ananthakrishnan AN, Sonnenberg A, Chan A, Sandler RS, Atreja A, Shah SA, Rothman KJ, Leleiko NS, Bright R, Boffetta P, Myers KD, Sands BE. Challenges in designing a national surveillance program for inflammatory bowel disease in the United States. Inflammatory Bowel Diseases. 2014;20(2):398-415. PMCID: PMC4610029. .
Long MD, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS. Risk factors for depression in the elderly inflammatory bowel disease population. Journal of Crohn's & Colitis. 2014;8(2):113-9. PMCID: PMC4589203.
Miller CA, Corbin KD, da Costa KA, Zhang S, Zhao X, Galanko JA, Blevins T, Bennett BJ, O'Connor A, Zeisel SH. Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study. The American Journal of Clinical Nutrition. 2014;100(3):778-86. PMCID: PMC4135488.
Nugent JL, McCoy AN, Addamo CJ, Jia W, Sandler RS, Keku TO. Altered tissue metabolites correlate with microbial dysbiosis in colorectal adenomas. Journal of Proteome Research. 2014;13(4):1921-9. PMCID: PMC3993967.
Pibiri F, Kittles RA, Sandler RS, Keku TO, Kupfer SS, Xicola RM, Llor X, Ellis NA. Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans. Cancer Causes & Control : CCC. 2014;25(5):561-70. PMCID: PMC3978221.
Randell RL, Long MD, Cook SF, Wrennall CE, Chen W, Martin CF, Anton K, Sandler RS, Kappelman MD. Validation of an internet-based cohort of inflammatory bowel disease (CCFA partners). Inflammatory Bowel Diseases. 2014;20(3):541-4. PMCID: PMC4112538.
Steck SE, Butler LM, Keku TO, Antwi S, Galanko J, Sandler RS, Hu JJ. Nucleotide excision repair gene polymorphisms, meat intake and colon cancer risk. Mutation Research. 2014;762:24-31. PMCID: PMC4056032.
Sundaram S, Freemerman AJ, Galanko JA, McNaughton KK, Bendt KM, Darr DB, Troester MA, Makowski L. Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice. PloS One. 2014;9(10):e111394. PMCID: PMC4213021.
Sundaram S, Le TL, Essaid L, Freemerman AJ, Huang MJ, Galanko JA, McNaughton KK, Bendt KM, Darr DB, Troester MA, Makowski L. Weight loss reversed obesity-induced HGF/c-Met pathway and basal-like breast cancer progression. Frontiers in Oncology. 2014;4:175. PMCID: PMC4085881.
Wang H, Burnett T, Kono S, Haiman CA, Iwasaki M, Wilkens LR, Loo LW, Van Den Berg D, Kolonel LN, Henderson BE, Keku TO, Sandler RS, Signorello LB, Blot WJ, Newcomb PA, Pande M, Amos CI, West DW, Bezieau S, Berndt SI, Zanke BW, Hsu L, Genetics, Epidemiology of Colorectal Cancer C, Lindor NM, Haile RW, Hopper JL, Jenkins MA, Gallinger S, Casey G, Colon Cancer Family R, Stenzel SL, Schumacher FR, Peters U, Gruber SB, Colorectal Transdisciplinary S, Tsugane S, Stram DO, Le Marchand L. Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nature Communications. 2014;5:4613. PMCID: PMC4180879.
Wasan SK, Calderwood AH, Long MD, Kappelman MD, Sandler RS, Farraye FA. Immunization rates and vaccine beliefs among patients with inflammatory bowel disease: an opportunity for improvement. Inflammatory Bowel Diseases. 2014;20(2):246-50. PMCID: PMC4393851.
Schoenborn AA, von Furstenberg RJ, Valsaraj S, Hussain FS, Stein M, Shanahan MT, Henning SJ, Gulati AS. The enteric microbiota regulates jejunal Paneth cell number and function without impacting intestinal stem cells. Gut Microbes. 2019;10(1):45-58. PMID: 29883265
Chen Y, Chaudhary N, Yang N, Granato A, Turner JA, Howard SL, Devereaux C, Zuo T, Shrestha A, Goel RR, Neuberg D, Wesemann DR. Microbial symbionts regulate the primary Ig repertoire. The Journal of Experimental Medicine. 2018;215(5):1397-415. PMCID: PMC5940265.
Ellermann M GR, Maharshak N, Perez-Chanona E, Jobin C, Carroll IM, Arthur JC, Plevy SL, Fodor AA, Brouwer, Sartor RB. Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice. Gut Microbes. 2018;accepted for publication.
Ho GT, Aird RE, Liu B, Boyapati RK, Kennedy NA, Dorward DA, Noble CL, Shimizu T, Carter RN, Chew ETS, Morton NM, Rossi AG, Sartor RB, Iredale JP, Satsangi J. MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. Mucosal Immunology. 2018;11(1):120-30. PMCID: PMC5510721.
Iyer SS, Gensollen T, Gandhi A, Oh SF, Neves JF, Collin F, Lavin R, Serra C, Glickman J, de Silva PSA, Sartor RB, Besra G, Hauser R, Maxwell A, Llebaria A, Blumberg RS. Dietary and microbial oxazoles induce intestinal inflammation by modulating aryl hydrocarbon receptor responses. Cell. 2018;173(5):1123-34.e11. PMCID: PMC6119676.
Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, Targan SR, Shih DQ. Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunology. 2018;11(5):1466-76. PMCID: PMC6162160.
Pushalkar S, Hundeyin M, Daley D, Zambirinis CP, Kurz E, Mishra A, Mohan N, Aykut B, Usyk M, Torres LE, Werba G, Zhang K, Guo Y, Li Q, Akkad N, Lall S, Wadowski B, Gutierrez J, Kochen Rossi JA, Herzog JW, Diskin B, Torres-Hernandez A, Leinwand J, Wang W, Taunk PS, Savadkar S, Janal M, Saxena A, Li X, Cohen D, Sartor RB, Saxena D, Miller G. The pancreatic cancer microbiome promotes oncogenesis by induction of innate and adaptive immune suppression. Cancer Discovery. 2018;8(4):403-16. PMCID: PMC6225783.
Rogala AR, Schoenborn AA, Fee BE, Cantillana VA, Joyce MJ, Gharaibeh RZ, Roy S, Fodor AA, Sartor RB, Taylor GA, Gulati AS. Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. Disease Models & Mechanisms. 2018;11(2). PMCID: PMC5894938. .
Schulfer AF, Battaglia T, Alvarez Y, Bijnens L, Ruiz VE, Ho M, Robinson S, Ward T, Cox LM, Rogers AB, Knights D, Sartor RB, Blaser MJ. Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol. 2018;3(2):234-42. PMCID: PMC5780248.
Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, Stienstra R, Sartor RB, Montgomery SA, Coleman RA, Ting JP. The inhibitory innate immune sensor NLRP12 maintains a threshold against obesity by regulating gut microbiota homeostasis. Cell Host & Microbe. 2018;24(3):364-78. PMCID: PMC6161752.
Ulici V, Kelley KL, Azcarate-Peril MA, Cleveland RJ, Sartor RB, Schwartz TA, Loeser RF. Osteoarthritis induced by destabilization of the medial meniscus is reduced in germ-free mice. Osteoarthritis and Cartilage. 2018;26(8):1098-109. PMID: 29857156
Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jorgensen TN, Leonard WJ, Li X. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nature Communications. 2018;9(1):2745. PMCID: PMC6048100.
Bartelt LA, Bolick DT, Mayneris-Perxachs J, Kolling GL, Medlock GL, Zaenker EI, Donowitz J, Thomas-Beckett RV, Rogala A, Carroll IM, Singer SM, Papin J, Swann JR, Guerrant RL. Cross-modulation of pathogen-specific pathways enhances malnutrition during enteric co-infection with Giardia lamblia and enteroaggregative Escherichia coli. PLoS Pathogens. 2017;13(7):e1006471. PMCID: PMC5549954.
Carr JS, King S, Dekaney CM. Depletion of enteric bacteria diminishes leukocyte infiltration following doxorubicin-induced small intestinal damage in mice. PloS One. 2017;12(3):e0173429. PMCID: PMC5336284.
Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nat Immunol. 2017;18(5):541-51. PMCID: PMC5395345.
Davison JM, Lickwar CR, Song L, Breton G, Crawford GE, Rawls JF. Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. Genome Research. 2017;27(7):1195-206. PMCID: PMC5495071.
Johnson BR, O'Flaherty S, Goh YJ, Carroll I, Barrangou R, Klaenhammer TR. The S-layer Associated Serine Protease Homolog PrtX Impacts cell surface-mediated microbe-host interactions of Lactobacillus acidophilus NCFM. Frontiers in Microbiology. 2017;8:1185. PMCID: PMC5491966.
Kang DJ, Hylemon PB, Gillevet PM, Sartor RB, Betrapally NS, Kakiyama G, Sikaroodi M, Takei H, Nittono H, Zhou H, Pandak WM, Yang J, Jiao C, Li X, Lippman HR, Heuman DM, Bajaj JS. Gut microbial composition can differentially regulate bile acid synthesis in humanized mice. Hepatology Communications. 2017;1(1):61-70. PMCID: PMC5747030.
Fung TC, Bessman NJ, Hepworth MR, Kumar N, Shibata N, Kobuley D, Wang K, Ziegler CG, Goc J, Shima T, Umesaki Y, Sartor RB, Sullivan KV, Lawley TD, Kunisawa J, Kiyono H, Sonnenberg GF. Lymphoid-tissue-resident commensal bacteria promote members of the IL-10 Cytokine family to establish mutualism. Immunity. 2016;44(3):634-46. PMCID: PMC4845739.
Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, Lippman HR, Sikaroodi M, Brown RR, Bajaj JS. Gut microbiota drive the development of neuroinflammatory response in cirrhosis in mice. Hepatology. 2016;64(4):1232-48. PMCID: PMC5033692.
Kang DJ, Kakiyama G, Betrapally NS, Herzog J, Nittono H, Hylemon PB, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Pandak WM, Iida T, Heuman DM, Fan S, Fiehn O, Kurosawa T, Sikaroodi M, Sartor RB, Bajaj JS. Rifaximin exerts beneficial effects independent of its ability to alter microbiota composition. Clin Transl Gastroenterol. 2016;7(8):e187. PMCID: PMC5543406.
Simon JM, Davis JP, Lee SE, Schaner MR, Gipson GR, Weiser M, Sartor RB, Herfarth HH, Rahbar R, Sadiq TS, Koruda MJ, McGovern DP, Lieb JD, Mohlke KL, Furey TS, Sheikh SZ. Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses. Eur J Immunol. 2016;46(8):1912-25. PMCID: PMC5486994.
Wu C, Sartor RB, Huang K, Tonkonogy SL. Transient activation of mucosal effector immune responses by resident intestinal bacteria in normal hosts is regulated by interleukin-10 signalling. Immunology. 2016;148(3):304-14. PMCID: PMC4913287.
Yan J, Herzog JW, Tsang K, Brennan CA, Bower MA, Garrett WS, Sartor RB, Aliprantis AO, Charles JF. Gut microbiota induce IGF-1 and promote bone formation and growth. Proceedings of the National Academy of Sciences of the United States of America. 2016;113(47):E7554-E63. PMCID: PMC5127374.
Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WH, DiDonato JA, Brown JM, Lusis AJ, Hazen SL. Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk. Cell. 2016;165(1):111-24. PMCID: PMC4862743.
Call EK, Goh YJ, Selle K, Klaenhammer TR, O'Flaherty S. Sortase-deficient lactobacilli: effect on immunomodulation and gut retention. Microbiology. 2015;161(Pt 2):311-21. PMCID: PMC4811640.
Goeser L, Fan TJ, Tchaptchet S, Stasulli N, Goldman WE, Sartor RB, Hansen JJ. Small heat-shock proteins, IbpAB, protect non-pathogenic Escherichia coli from killing by macrophage-derived reactive oxygen species. PloS One. 2015;10(3):e0120249. PMCID: PMC4370416.
Kubinak JL, Petersen C, Stephens WZ, Soto R, Bake E, O'Connell RM, Round JL. MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health. Cell Host & Microbe. 2015;17(2):153-63. : PMC4451207.
Kubinak JL, Stephens WZ, Soto R, Petersen C, Chiaro T, Gogokhia L, Bell R, Ajami NJ, Petrosino JF, Morrison L, Potts WK, Jensen PE, O'Connell RM, Round JL. MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection. Nature Communications. 2015;6:8642. PMCID: PMC4621775.
Maharshak N, Ryu HS, Fan TJ, Onyiah JC, Schulz S, Otterbein SL, Wong R, Hansen JJ, Otterbein LE, Carroll IM, Plevy SE. Escherichia coli heme oxygenase modulates host innate immune responses. Microbiology and Immunology. 2015;59(8):452-65. PMCID: PMC4582649
Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2015;29(3):1043-55. PMCID: PMC4422368.
Mishima Y, Liu B, Hansen JJ, Sartor RB. Resident bacteria-stimulated IL-10-secreting B cells ameliorate T cell-mediated colitis by inducing Tr-1 cells that require IL-27-signaling. Cellular and Molecular Gastroenterology and Hepatology. 2015;1(3):295-310. PMCID: PMC4448782.
Camp JG, Frank CL, Lickwar CR, Guturu H, Rube T, Wenger AM, Chen J, Bejerano G, Crawford GE, Rawls JF. Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape. Genome Research. 2014;24(9):1504-16. PMCID: PMC4158762.
Dogan B, Suzuki H, Herlekar D, Sartor RB, Campbell BJ, Roberts CL, Stewart K, Scherl EJ, Araz Y, Bitar PP, Lefebure T, Chandler B, Schukken YH, Stanhope MJ, Simpson KW. Inflammation-associated adherent-invasive Escherichia coli are enriched in pathways for use of propanediol and iron and M-cell translocation. Inflammatory Bowel Diseases. 2014;20(11):1919-32. PMID: 25230163
Donohoe DR, Holley D, Collins LB, Montgomery SA, Whitmore AC, Hillhouse A, Curry KP, Renner SW, Greenwalt A, Ryan EP, Godfrey V, Heise MT, Threadgill DS, Han A, Swenberg JA, Threadgill DW, Bultman SJ. A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner. Cancer Discovery. 2014;4(12):1387-97. : PMC4258155.
Eun CS, Mishima Y, Wohlgemuth S, Liu B, Bower M, Carroll IM, Sartor RB. Induction of bacterial antigen-specific colitis by a simplified human microbiota consortium in gnotobiotic interleukin-10-/- mice. Infection and Immunity. 2014;82(6):2239-46. : PMC4019192.
Goh YJ, Klaenhammer TR. Insights into glycogen metabolism in Lactobacillus acidophilus: impact on carbohydrate metabolism, stress tolerance and gut retention. Microbial Cell Factories. 2014;13:94. PMCID: PMC4243779.
Harley IT, Stankiewicz TE, Giles DA, Softic S, Flick LM, Cappelletti M, Sheridan R, Xanthakos SA, Steinbrecher KA, Sartor RB, Kohli R, Karp CL, Divanovic S. IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. Hepatology. 2014;59(5):1830-9. PMCID: PMC3975735.
Kobayashi T, Steinbach EC, Russo SM, Matsuoka K, Nochi T, Maharshak N, Borst LB, Hostager B, Garcia-Martinez JV, Rothman PB, Kashiwada M, Sheikh SZ, Murray PJ, Plevy SE. NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis. Journal of Immunology. 2014;192(4):1918-27. : PMC3948213.
Lindenstrauss AG, Ehrmann MA, Behr J, Landstorfer R, Haller D, Sartor RB, Vogel RF. Transcriptome analysis of Enterococcus faecalis toward its adaption to surviving in the mouse intestinal tract. Archives of Microbiology. 2014;196(6):423-33. PMID: 24700373
Morgan AP, Crowley JJ, Nonneman RJ, Quackenbush CR, Miller CN, Ryan AK, Bogue MA, Paredes SH, Yourstone S, Carroll IM, Kawula TH, Bower MA, Sartor RB, Sullivan PF. The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse. PloS One. 2014;9(12):e115225. : PMC4266663.
Oh JZ, Ravindran R, Chassaing B, Carvalho FA, Maddur MS, Bower M, Hakimpour P, Gill KP, Nakaya HI, Yarovinsky F, Sartor RB, Gewirtz AT, Pulendran B. TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination. Immunity. 2014;41(3):478-92. PMCID: PMC4169736.
Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL, Flavell RA. Immunoglobulin a coating identifies colitogenic bacteria in inflammatory bowel disease. Cell. 2014;158(5):1000-10. PMCID: PMC4174347.
Perez-Chanona E, Muhlbauer M, Jobin C. The microbiota protects against ischemia/reperfusion-induced intestinal injury through nucleotide-binding oligomerization domain-containing protein 2 (NOD2) signaling. The American Journal of Pathology. 2014;184(11):2965-75. : PMC4215024.
Shanahan MT, Carroll IM, Grossniklaus E, White A, von Furstenberg RJ, Barner R, Fodor AA, Henning SJ, Sartor RB, Gulati AS. Mouse Paneth cell antimicrobial function is independent of Nod2. Gut. 2014;63(6):903-10. : PMC3844066.
Waldschmitt N, Berger E, Rath E, Sartor RB, Weigmann B, Heikenwalder M, Gerhard M, Janssen KP, Haller D. C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely regulated with chronic inflammation. Mucosal Immunology. 2014;7(6):1452-66.
Wuensch T, Ullrich S, Schulz S, Chamaillard M, Schaltenberg N, Rath E, Goebel U, Sartor RB, Prager M, Buning C, Bugert P, Witt H, Haller D, Daniel H. Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation. Inflammatory Bowel Diseases. 2014;20(4):671-84. PMID: 24583477
Hill TL, Lascelles BDX, Blikslager AT. Effect of sucralfate on gastric permeability in an ex vivo model of stress-related mucosal disease in dogs. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 2018;32(2):670-8. PMCID: PMCPMC5866966.
Jin Y, Ibrahim DR, Magness ST, Blikslager AT. Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity. American Journal of Physiology Gastrointestinal and Liver Physiology. 2018. PMCID: PMC6336945
Kucera CR, Stranahan LW, Hughes F, Blikslager AT, Gonzalez LM. Protein biomarker of cell proliferation determines survival to discharge in cases of equine large colon volvulus. Equine Veterinary Journal. 2018;50(4):452-6. PMCID: PMC5899956.
Lima HK, Lin X, Jacobi SK, Man C, Sommer J, Flowers W, Blikslager A, Gonzalez L, Odle J. Supplementation of maternal diets with docosahexaenoic acid and methylating vitamins impacts growth and development of fetuses from malnourished Gilts. Curr Dev Nutr. 2018;2(3):nzx006. PMCID: PMC6204386.
Stieler Stewart A, Freund JM, Blikslager AT, Gonzalez LM. Intestinal stem cell isolation and culture in a porcine model of segmental small intestinal ischemia. Journal of Visualized Experiments : JoVE. 2018(135). PMCID: PMC6101266.
Zhang Q, Ke H, Blikslager A, Fujita T, Yoo D. Type III interferon restriction by porcine epidemic diarrhea virus and the role of viral protein nsp1 in IRF1 signaling. J Virol. 2018;92(4). PMCID: PMC5790939.
Ziegler AL, Pridgen TA, Mills JK, Gonzalez LM, Van Landeghem L, Odle J, Blikslager AT. Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair. PloS One. 2018;13(8):e0200674. PMCID: PMC6107120.
Fogle J, Jacob M, Blikslager A, Edwards A, Wagner B, Dean K, Fogle C. Comparison of lipopolysaccharides and soluble CD14 measurement between clinically endotoxaemic and nonendotoxaemic horses. Equine Veterinary Journal. 2017;49(2):155-9. PMID: 27060869
Jin Y, Blikslager AT. Intestinal ischemia-reperfusion: rooting for the SOCS? Digestive Diseases and Sciences. 2017;62(1):4-6. PMCID: PMC5218974.
Kruger L, Gonzalez LM, Pridgen TA, McCall SJ, von Furstenberg R, Harnden I, Carnighan GE, Cox AM, Blikslager AT, Garman KS. Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair. American Journal of Physiology Gastrointestinal and Liver Physiology. 2017;313(3)G180-91. PMCID: PMC5625137
Stewart AS, Freund JM, Gonzalez LM. Advanced three-dimensional culture of equine intestinal epithelial stem cells. Equine Veterinary Journal. 2018;50(2)241-48. PMCID: PMC5796842
von Furstenberg RJ, Li J, Stolarchuk C, Feder R, Campbell A, Kruger L, Gonzalez LM, Blikslager AT, Cardona DM, McCall SJ, Henning SJ, Garman KS. Porcine esophageal submucosal gland culture model shows capacity for proliferation and differentiation. Cellular and Molecular Gastroenterology and Hepatology. 2017;4(3):385-404. PMCID: PMC5602779.
Ziegler A, Fogle C, Blikslager A. Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses. J Am Vet Med Assoc. 2017;250(11):1271-4. PMCID: PMC5588883
Ziegler AL, Blikslager AT. Impaired intestinal barrier function and relapsing digestive disease: Lessons from a porcine model of early life stress. Neurogastroenterol Motil. 2017;29(11):1-4. PMCID: PMC5940449.
Meliopoulos VA, Marvin SA, Freiden P, Moser LA, Nighot P, Ali R, Blikslager A, Reddivari M, Heath RJ, Koci MD, Schultz-Cherry S. Oral administration of astrovirus capsid protein is sufficient to induce acute diarrhea in vivo. MBio. 2016;7(6). PMCID: PMC5090040.
Ziegler A, Gonzalez L, Blikslager A. Large Animal Models: The key to translational discovery in digestive disease research. Cellular and Molecular Gastroenterology and Hepatology. 2016;2(6):716-24. PMCID: PMC5235339.
Gonzalez LM, Kinnin LA, Blikslager AT. Characterization of discrete equine intestinal epithelial cell lineages. American journal of Veterinary Research. 2015;76(4):358-66. : PMC4517574.
Gonzalez LM, Moeser AJ, Blikslager AT. Animal models of ischemia-reperfusion-induced intestinal injury: progress and promise for translational research. American Journal of Physiology Gastrointestinal and Liver Physiology. 2015;308(2):G63-75. PMCID: PMC4297854.
Hill TL, Lascelles BD, Law JM, Blikslager AT. The effect of tramadol and indomethacin coadministration on gastric barrier function in dogs. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 2014;28(3):793-8. PMCID: PMC4497006.
Arnold JW, Simpson JB, Roach J, Kwintkiewicz J, Azcarate-Peril MA. Intra-species genomic and physiological variability impact stress resistance in strains of probiotic potential. Frontiers in Microbiology. 2018;9. PMCID: PMC5826259
Jones RB, Zhu X, Moan E, Murff HJ, Ness RM, Seidner DL, Sun S, Yu C, Dai Q, Fodor AA, Azcarate-Peril MA, Shrubsole MJ. Inter-niche and inter-individual variation in gut microbial community assessment using stool, rectal swab, and mucosal samples. Scientific Reports. 2018;8(1). PMCID: PMC5841359
Lee MK, Carnes MU, Butz N, Azcarate-Peril MA, Richards M, Umbach DM, Thorne PS, Beane Freeman LE, Peddada SD, London SJ. Exposures related to house dust microbiota in a U.S. farming population. Environmental Health Perspectives. 2018;126(6):067001. PMCID: PMC6084882
Allali I, Arnold JW, Roach J, Cadenas MB, Butz N, Hassan HM, Koci M, Ballou A, Mendoza M, Ali R, Azcarate-Peril MA. A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome. BMC Microbiology. 2017;17(1). PMCID: PMC5598039
Anderson JR, Carroll I, Azcarate-Peril MA, Rochette AD, Heinberg LJ, Peat C, Steffen K, Manderino LM, Mitchell J, Gunstad J. A preliminary examination of gut microbiota, sleep, and cognitive flexibility in healthy older adults. Sleep Medicine. 2017;38:104-7. PMID: 29031742
Arnold JW, Monteagudo-Mera A, Altermann E, Cadenas MB, Thompson AL, Azcarate-Peril MA. Genome sequences of potential probiotic Lactobacillus rhamnosus isolates from human infants. Genome Announcements. 2017;5(14).
Azcarate-Peril MA, Butz N, Cadenas MB, Koci M, Ballou A, Mendoza M, Ali R, Hassan H. An attenuated salmonella enterica serovar Typhimurium strain and galacto-oligosaccharides accelerate clearance of salmonella infections in poultry through modifications to the gut microbiome. Applied and Environmental Microbiology. 2017;84(5). PMCID: PMC5812947
Carlson AL, Xia K, Azcarate-Peril MA, Goldman BD, Ahn M, Styner MA, Thompson AL, Geng X, Gilmore JH, Knickmeyer RC. Infant gut microbiome associated with cognitive development. Biol Psychiatry. 2017;83(2):148-59. PMCID: PMC5724966.
Furquim CP, Soares GM, Ribeiro LL, Azcarate-Peril MA, Butz N, Roach J, Moss K, Bonfim C, Torres-Pereira CC, Teles FR. The salivary microbiome and oral cancer risk: a pilot study in Fanconi Anemia. J Dent Res. 2017;96(3):292-9. PMCID: PMC5298391.
Gray J, Oehrle K, Worthen G, Alenghat T, Whitsett J, Deshmukh H. Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection. Sci Transl Med. 2017;9(376). PMCID: PMC5880204
Manderino L, Carroll I, Azcarate-Peril MA, Rochette A, Heinberg L, Peat C, Steffen K, Mitchell J, Gunstad J. Preliminary evidence for an association between the composition of the gut microbiome and cognitive function in neurologically healthy older adults. J Int Neuropsychol Soc. 2017:1-6. PMID: 29031742
Perez-Diaz IM, Hayes J, Medina E, Anekella K, Daughtry K, Dieck S, Levi M, Price R, Butz N, Lu Z, Azcarate-Peril MA. Reassessment of the succession of lactic acid bacteria in commercial cucumber fermentations and physiological and genomic features associated with their dominance. Food Microbiol. 2017;63:217-27. PMID: 28040172
Ribeiro AA, Azcarate-Peril MA, Cadenas MB, Butz N, Paster BJ, Chen T, Bair E, Arnold RR. The oral bacterial microbiome of occlusal surfaces in children and its association with diet and caries. PloS One. 2017;12(7):e0180621. PMCID: PMC5498058.
Romano-Keeler J, Azcarate-Peril MA, Weitkamp JH, Slaughter JC, McDonald WH, Meng S, Latuga MS, Wynn JL. Oral colostrum priming shortens hospitalization without changing the immunomicrobial milieu. Journal of Perinatology : official journal of the California Perinatal Association. 2017;37(1):36-41. PMCID: PMC5215726.
Sandoval-Espinola WJ, Chinn MS, Thon MR, Bruno-Bárcena JM. Evidence of mixotrophic carbon-capture by n-butanol-producer Clostridium beijerinckii. Scientific Reports. 2017;7(1).
Sanz-Martin I, Doolittle-Hall J, Teles RP, Patel M, Belibasakis GN, Hämmerle CHF, Jung RE, Teles FRF. Exploring the microbiome of healthy and diseased peri-implant sites using Illumina sequencing. Journal of Clinical Periodontology. 2017;44(12):1274-84. PMID: 28766745
Seidel DV, Azcarate-Peril MA, Chapkin RS, Turner ND. Shaping functional gut microbiota using dietary bioactives to reduce colon cancer risk. Semin Cancer Biol. 2017. PMCID: PMC5626600
Smid MC, Ricks NM, Panzer A, McCoy AN, Azcarate-Peril MA, Keku TO, Boggess KA. Maternal gut microbiome biodiversity in pregnancy. Am J Perinatol. 2017. PMCID: PMC6102712
Stepper P, Kungulovski G, Jurkowska RZ, Chandra T, Krueger F, Reinhardt R, Reik W, Jeltsch A, Jurkowski TP. Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase. Nucleic Acids Research. 2017;45(4):1703-13. PMCID: PMC5389507.
Walker MY, Pratap S, Southerland JH, Farmer-Dixon CM, Lakshmyya K, Gangula PR. Role of oral and gut microbiome in nitric oxide-mediated colon motility. Nitric Oxide. 2017.
Wellman AS, Metukuri MR, Kazgan N, Xu X, Xu Q, Ren NSX, Czopik A, Shanahan MT, Kang A, Chen W, Azcarate-Peril MA, Gulati AS, Fargo DC, Guarente L, Li X. Intestinal Epithelial Sirtuin 1 regulates intestinal inflammation during aging in mice by altering the intestinal microbiota. Gastroenterology. 2017. PMCID: PMC5581719
Whitham JM, Schulte MJ, Bobay BG, Bruno-Barcena JM, Chinn MS, Flickinger MC, Pawlak JJ, Grunden AM. Characterization of Clostridium ljungdahlii OTA1: a non-autotrophic hyper ethanol-producing strain. Applied Microbiology and Biotechnology. 2017;101(4):1615-30. PMID: 27866253
Dagher SF, Bruno-Barcena JM. A novel N-terminal region of the membrane beta-hexosyltransferase: its role in secretion of soluble protein by Pichia pastoris. Microbiology. 2016;162(1):23-34. PMCID: PMC5974927
Emami-Khoyi A, Hartley DA, Ross JG, Murphy EC, Paterson AM, Cruickshank RH, Else TA. Complete mitochondrial genome of the stoat (Mustela erminea) and New Zealand fur seal (Arctocephalus forsteri) and their significance for mammalian phylogeny. Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27(6):4597-9. PMID: 27246241
Fromen CA, Rahhal TB, Robbins GR, Kai MP, Shen TW, Luft JC, DeSimone JM. Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells. Nanomedicine. 2016;12(3):677-87. PMCID: PMC4839472.
Grogan KE, McGinnis GJ, Sauther ML, Cuozzo FP, Drea CM. Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications. BMC Genomics. 2016;17:204. PMCID: PMC4782575.
Mideo N, Bailey JA, Hathaway NJ, Ngasala B, Saunders DL, Lon C, Kharabora O, Jamnik A, Balasubramanian S, Bjorkman A, Martensson A, Meshnick SR, Read AF, Juliano JJ. A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections. Evol Med Public Health. 2016;2016(1):21-36. PMCID: PMC4753362.
Twitchell EL, Tin C, Wen K, Zhang H, Becker-Dreps S, Azcarate-Peril MA, Vilchez S, Li G, Ramesh A, Weiss M, Lei S, Bui T, Yang X, Schultz-Cherry S, Yuan L. Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs. Gut Pathog. 2016;8:51. PMCID: PMC5100090.
Allali I, Delgado S, Marron PI, Astudillo A, Yeh JJ, Ghazal H, Amzazi S, Keku T, Azcarate-Peril MA. Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain. Gut Microbes. 2015;6(3):161-72. PMCID: PMC4615176
Bahr SM, Tyler BC, Wooldridge N, Butcher BD, Burns TL, Teesch LM, Oltman CL, Azcarate-Peril MA, Kirby JR, Calarge CA. Use of the second-generation antipsychotic, risperidone, and secondary weight gain are associated with an altered gut microbiota in children. Transl Psychiatry. 2015;5:e652. PMCID: PMC4930121
Becker-Dreps S, Allali I, Monteagudo A, Vilchez S, Hudgens MG, Rogawski ET, Carroll IM, Zambrana LE, Espinoza F, Azcarate-Peril MA. Gut microbiome composition in young Nicaraguan children during diarrhea episodes and recovery. The American Journal of Tropical Medicine and Hygiene. 2015;93(6):1187-93. PMCID: PMC4674233.
Bruno-Barcena JM, Azcarate-Peril MA. Galacto-oligosaccharides and colorectal cancer: feeding our intestinal probiome. Journal of Functional Foods. 2015;12:92-108. PMCID: PMC4288025.
Keys JR, Zhou S, Anderson JA, Eron JJ, Jr., Rackoff LA, Jabara C, Swanstrom R. Primer ID informs next-generation sequencing platforms and reveals preexisting drug resistance mutations in the HIV-1 Reverse Transcriptase Coding Domain. AIDS Research and Human Retroviruses. 2015;31(6):658-68. : PMC4458739.
Kleiman SC, Watson HJ, Bulik-Sullivan EC, Huh EY, Tarantino LM, Bulik CM, Carroll IM. The intestinal microbiota in acute anorexia nervosa and during renourishment: relationship to depression, anxiety, and eating eisorder psychopathology. Psychosom Med. 2015;77(9):969-81. PMCID: PMC4643361.
Moffitt RA, Marayati R, Flate EL, Volmar KE, Loeza SG, Hoadley KA, Rashid NU, Williams LA, Eaton SC, Chung AH, Smyla JK, Anderson JM, Kim HJ, Bentrem DJ, Talamonti MS, Iacobuzio-Donahue CA, Hollingsworth MA, Yeh JJ. Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma. Nature Genetics. 2015;47(10):1168-78. PMCID: PMC4912058.
Noar J, Loveless T, Navarro-Herrero JL, Olson JW, Bruno-Barcena JM. Aerobic Hydrogen Production via Nitrogenase in Azotobacter vinelandii CA6. Applied and Environmental Microbiology. 2015;81(13):4507-16. PMCID: PMC4475890.
Reina LD, Perez-Diaz IM, Breidt F, Azcarate-Peril MA, Medina E, Butz N. Characterization of the microbial diversity in yacon spontaneous fermentation at 20 degrees C. International Journal of Food Microbiology. 2015;203:35-40.
Ringel Y, Maharshak N, Ringel-Kulka T, Wolber EA, Sartor RB, Carroll IM. High throughput sequencing reveals distinct microbial populations within the mucosal and luminal niches in healthy individuals. Gut Microbes. 2015;6(3):173-81. PMCID: PMC4615648
Ritchie LE, Sturino JM, Carroll RJ, Rooney LW, Azcarate-Peril MA, Turner ND. Polyphenol-rich sorghum brans alter colon microbiota and impact species diversity and species richness after multiple bouts off dextran sodium sulfate-induced colitis. FEMS Microbiology Ecology. 2015;91(3). PMCID: PMC4573659
Ritchie LE, Taddeo SS, Weeks BR, Lima F, Bloomfield SA, Azcarate-Peril MA, Zwart SR, Smith SM, Turner ND. Space environmental factor impacts upon murine colon microbiota and mucosal homeostasis. PloS One. 2015;10(6):e0125792. PMCID: PMC4470690.
Rodgers-Vieira EA, Zhang Z, Adrion AC, Gold A, Aitken MD. Identification of anthraquinone-degrading bacteria in soil contaminated with polycyclic aromatic hydrocarbons. Applied and Environmental Microbiology. 2015;81(11):3775-81. PMCID: PMC4421061.
Thompson AL, Monteagudo-Mera A, Cadenas MB, Lampl ML, Azcarate-Peril MA. Milk- and solid-feeding practices and daycare attendance are associated with differences in bacterial diversity, predominant communities, and metabolic and immune function of the infant gut microbiome. Frontiers in Cellular and Infection Microbiology. 2015;5:3. PMCID: PMC4318912.
Tzanetakis GN, Azcarate-Peril MA, Zachaki S, Panopoulos P, Kontakiotis EG, Madianos PN, Divaris K. Comparison of bacterial community composition of primary and persistent endodontic infections using pyrosequencing. Journal of Endodontics. 2015;41(8):1226-33. PMCID: PMC4578635
Utturkar SM, Klingeman DM, Bruno-Barcena JM, Chinn MS, Grunden AM, Kopke M, Brown SD. Sequence data for Clostridium autoethanogenum using three generations of sequencing technologies. Scientific data. 2015;2:150014. PMCID: PMC4409012.
Van Treuren W, Ponnusamy L, Brinkerhoff RJ, Gonzalez A, Parobek CM, Juliano JJ, Andreadis TG, Falco RC, Ziegler LB, Hathaway N, Keeler C, Emch M, Bailey JA, Roe RM, Apperson CS, Knight R, Meshnick SR. Variation in the microbiota of ixodes ticks with regard to geography, species, and sex. Applied and Environmental Microbiology. 2015;81(18):6200-9. PMCID: PMC4542252
Zhao N, Chen J, Carroll IM, Ringel-Kulka T, Epstein MP, Zhou H, Zhou JJ, Ringel Y, Li H, Wu MC. Testing in microbiome-profiling studies with MiRKAT, the microbiome regression-based Kernel Association Test. American Journal of Human Genetics. 2015;96(5):797-807. PMCID: PMC4570290
Deshmukh HS, Liu Y, Menkiti OR, Mei J, Dai N, O'Leary CE, Oliver PM, Kolls JK, Weiser JN, Worthen GS. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nature Medicine. 2014;20(5):524-30. PMCID: PMC4016187.
Ibarbalz FM, Perez MV, Figuerola EL, Erijman L. The bias associated with amplicon sequencing does not affect the quantitative assessment of bacterial community dynamics. PloS One. 2014;9(6):e99722. PMCID: PMC4055690.
Ponnusamy L, Gonzalez A, Van Treuren W, Weiss S, Parobek CM, Juliano JJ, Knight R, Roe RM, Apperson CS, Meshnick SR. Diversity of Rickettsiales in the microbiome of the lone star tick, Amblyomma americanum. Applied and Environmental Microbiology. 2014;80(1):354-9. PMCID: PMC3910995.
Sofi MH, Gudi R, Karumuthil-Melethil S, Perez N, Johnson BM, Vasu C. pH of drinking water influences the composition of gut microbiome and type 1 diabetes incidence. Diabetes. 2014;63(2):632-44. PMCID: PMC3900548.
Byrne JD, Jajja MRN, O'Neill AT, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer. Cancer Chemotherapy and Pharmacology. 2018;81(6):991-8. PMID: 29603014
Battaglia RA, Kabiraj P, Willcockson HH, Lian M, Snider NT. Isolation of intermediate filament proteins from multiple mouse tissues to study aging-associated post-translational Modifications. Journal of Visualized Experiments : JoVE. 2017(123). PMCID: PMC5603907.
Dellon ES, Veerappan R, Selitsky SR, Parker JS, Higgins LL, Beitia R, Genta RM, Lash RH. A gene expression panel is accurate for diagnosis and monitoring treatment of Eosinophilic Esophagitis in adults. Clin Transl Gastroenterol. 2017;8(2):e74. PMCID: PMC5387749.
Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC. Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunology. 2017;10(2):395-407. PMCID: PMC5250616.
Minchin JEN, Rawls JF. A classification system for zebrafish adipose tissues. Disease Models & Mechanisms. 2017;10(6):797-809. PMCID: PMC5482999.
Rusin S, Covey S, Perjar I, Hollyfield J, Speck O, Woodward K, Woosley JT, Dellon ES. Determination of esophageal eosinophil counts and other histologic features of eosinophilic esophagitis by pathology trainees is highly accurate. Human Pathology. 2017;62:50-5. PMCID: PMC5392430.
Berkoff DJ, Kallianos SA, Eskildsen SM, Weinhold PS. Use of an IL1-receptor antagonist to prevent the progression of tendinopathy in a rat model. J Orthop Res. 2016;34(4):616-22. PMID:26418607
Burk CM, Beitia R, Lund PK, Dellon ES. High rate of galactose-alpha-1,3-galactose sensitization in both eosinophilic esophagitis and patients undergoing upper endoscopy. Diseases of the Esophagus : official journal of the International Society for Diseases of the Esophagus / ISDE. 2016;29(6):558-62. PMCID: PMC4580560.
Byrne JD, Jajja MR, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 2016;113(8):2200-5. PMCID: PMC4776454.
Dellon ES, Cotton CC, Gebhart JH, Higgins LL, Beitia R, Woosley JT, Shaheen NJ. Accuracy of the Eosinophilic Esophagitis Endoscopic Reference Score in diagnosis and determining response to treatment. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016;14(1):31-9. PMCID: PMC4690779.
Monteagudo-Mera A, Arthur JC, Jobin C, Keku T, Bruno-Barcena JM, Azcarate-Peril MA. High purity galacto-oligosaccharides enhance specific Bifidobacterium species and their metabolic activity in the mouse gut microbiome. Benef Microbes. 2016;7(2):247-64. PMCID: PMC4974821.
Mottawea W, Chiang CK, Muhlbauer M, Starr AE, Butcher J, Abujamel T, Deeke SA, Brandel A, Zhou H, Shokralla S, Hajibabaei M, Singleton R, Benchimol EI, Jobin C, Mack DR, Figeys D, Stintzi A. Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohn's disease. Nature Communications. 2016;7:13419. PMCID: PMC5122959 .
Snider NT, Portney DA, Willcockson HH, Maitra D, Martin HC, Greenson JK, Omary MB. Ethanol and acetaminophen synergistically induce hepatic aggregation and TCH346-insensitive nuclear translocation of GAPDH. PloS One. 2016;11(8):e0160982. PMCID: PMC4981434.
Winston JA, Thanissery R, Montgomery SA, Theriot CM. Cefoperazone-treated mouse model of clinically-relevant Clostridium difficile strain R20291. Journal of Visualized Experiments : JoVE. 2016(118). PMCID: PMC5226375.
Andres SF, Santoro MA, Mah AT, Keku JA, Bortvedt AE, Blue RE, Lund PK. Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs. American Journal of Physiology Gastrointestinal and Liver Physiology. 2015;308(2):G100-11. PMCID: PMC4297856.
Borras T, Smith MH, Buie LK. A novel Mgp-Cre knock-in mouse reveals an anticalcification/antistiffness candidate gene in the trabecular meshwork and peripapillary scleral region. Investigative Ophthalmology & Visual Science. 2015;56(4):2203-14. PMCID: PMC4406033.
Dellon ES, Speck O, Woodward K, Covey S, Rusin S, Shaheen NJ, Woosley JT. Distribution and variability of esophageal eosinophilia in patients undergoing upper endoscopy. Modern Pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2015;28(3):383-90. : PMC4344855.
Hathaway CK, Gasim AM, Grant R, Chang AS, Kim HS, Madden VJ, Bagnell CR, Jr., Jennette JC, Smithies O, Kakoki M. Low TGFbeta1 expression prevents and high expression exacerbates diabetic nephropathy in mice. Proceedings of the National Academy of Sciences of the United States of America. 2015;112(18):5815-20. : PMC4426439.
Hathaway CK, Grant R, Hagaman JR, Hiller S, Li F, Xu L, Chang AS, Madden VJ, Bagnell CR, Rojas M, Kim HS, Wu B, Zhou B, Smithies O, Kakoki M. Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade. Proceedings of the National Academy of Sciences of the United States of America. 2015;112(16):5141-6. PMCID: PMC4413291.
Keku TO, Dulal S, Deveaux A, Jovov B, Han X. The gastrointestinal microbiota and colorectal cancer. American Journal of Physiology Gastrointestinal and Liver Physiology. 2015;308(5):G351-63. : PMC4346754.
Matsuki K, Hathaway CK, Chang AS, Smithies O, Kakoki M. Transforming growth factor beta1 and aldosterone. Current Opinion in Nephrology and Hypertension. 2015;24(2):139-44. PMCID: PMC4838512
Pechous RD, Broberg CA, Stasulli NM, Miller VL, Goldman WE. In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation. MBio. 2015;6(1):e02302-14. : PMC4337571.
Shen X, Xi G, Wai C, Clemmons DR. The coordinate cellular response to insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-2 (IGFBP-2) is regulated through vimentin binding to receptor tyrosine phosphatase beta (RPTPbeta). The Journal of Biological Chemistry. 2015;290(18):11578-90. PMCID: PMC4416861.
Sivaraman V, Pechous RD, Stasulli NM, Eichelberger KR, Miao EA, Goldman WE. Yersinia pestis activates both IL-1beta and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. PLoS Pathogens. 2015;11(3):e1004688. PMCID: PMC4363893.
Stasulli NM, Eichelberger KR, Price PA, Pechous RD, Montgomery SA, Parker JS, Goldman WE. Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague. MBio. 2015;6(5):e01530-15. PMCID: PMC4620470.
Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, Oikawa T, Whitmire JK, Heise MT, Dittmer DP, Kao CC, Pitson SM, Merrill AH, Jr., Reid LM, Lemon SM, Harrill JA, Parks BB, Wauthier E, Rowlands JC, Reid LM, Thomas RS. Lineage-dependent effects of aryl hydrocarbon receptor agonists contribute to liver tumorigenesis. Nature Medicine. 2015;61(2):548-60. PMCID: PMC4126843 Europe PMC4303521.
Wolf WA, Cotton CC, Green DJ, Hughes JT, Woosley JT, Shaheen NJ, Dellon ES. Evaluation of histologic cutpoints for treatment response in eosinophilic esophagitis. Journal of Gastroenterology and Hepatology Research. 2015;4(10):1780-7. PMCID: PMC4838410.
Dellon ES, Speck O, Woodward K, Covey S, Rusin S, Gebhart JH, D, Woosley JT, Shaheen NJ. Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study. Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association. 2014;12(12):2015-22. PMCID: PMC4252508.
Ding S, Blue RE, Morgan DR, Lund PK. Comparison of multiple enzyme activatable near-infrared fluorescent molecular probes for detection and quantification of inflammation in murine colitis models. Inflammatory Bowel Diseases. 2014;20(2):363-77. PMCID: PMC4618379
Dulal S, Keku TO. Gut microbiome and colorectal adenomas. Cancer Journal. 2014;20(3):225-31. PMCID: PMC4589167
Kanther M, Tomkovich S, Xiaolun S, Grosser MR, Koo J, Flynn EJ, 3rd, Jobin C, Rawls JF. Commensal microbiota stimulate systemic neutrophil migration through induction of Serum amyloid A. Cellular Microbiology. 2014;16(7):1053-67. : PMC4364439.
Ringel-Kulka T, Goldsmith JR, Carroll IM, Barros SP, Palsson O, Jobin C, Ringel Y. Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study. Alimentary Pharmacology & Therapeutics. 2014;40(2):200-7. PMCID: PMC4613798
Schuck RN, Zha W, Edin ML, Gruzdev A, Vendrov KC, Miller TM, Xu Z, Lih FB, DeGraff LM, Tomer KB, Jones HM, Makowski L, Huang L, Poloyac SM, Zeldin DC, Lee CR. The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease. PloS One. 2014;9(10):e110162. PMCID: PMC4195706.
Sepulveda VE, Williams CL, Goldman WE. Comparison of phylogenetically distinct histoplasma strains reveals evolutionarily divergent virulence strategies. MBio. 2014;5(4):e01376-14. PMCID: PMC4161242.
Shah PK, Herrera-Loeza SG, Sims CE, Yeh JJ, Allbritton NL. Small sample sorting of primary adherent cells by automated micropallet imaging and release. Cytometry Part A : the journal of the International Society for Analytical Cytology. 2014;85(7):642-9.
Shanahan MT, Carroll IM, Gulati AS. Critical design aspects involved in the study of Paneth cells and the intestinal microbiota. Gut Microbes. 2014;5(2):208-14. PMCID: PMC4063846.
Torphy RJ, Tignanelli CJ, Kamande JW, Moffitt RA, Herrera Loeza SG, Soper SA, Yeh JJ. Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma. PloS One. 2014;9(2):e89474. PMCID: PMC3929698.
von Furstenberg RJ, Buczacki SJ, Smith BJ, Seiler KM, Winton DJ, Henning SJ. Side population sorting separates subfractions of cycling and non-cycling intestinal stem cells. Stem Cell Research. 2014;12(2):364-75. PMCID: PMC3951668.
Yamane D, McGivern DR, Wauthier E, Yi M, Madden VJ. Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation. Nat Med 2014;20(8):927-35. PMCID: PMC4126843
Zha W, Edin ML, Vendrov KC, Schuck RN, Lih FB, Jat JL, Bradbury JA, DeGraff LM, Hua K, Tomer KB, Falck JR, Zeldin DC, Lee CR. Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity. Journal of Lipid Research. 2014;55(10):2124-36. PMCID PMC4174005.
Hoover B, Baena V, Kaelberer MM, Getaneh F, Chinchilla S, Bohorquez DV. The intestinal tuft cell nanostructure in 3D. Scientific Reports. 2017;7(1):1652. PMCID: PMC5431925.
Liang J, Huang HI, Benzatti FP, Karlsson AB, Zhang JJ, Youssef N, Ma A, Hale LP, Hammer GE. Inflammatory Th1 and Th17 in the intestine are each driven by functionally specialized dendritic cells with distinct requirements for MyD88. Cell Rep. 2016;17(5):1330-43. PMCID: PMC5123685.
Weiser M, Simon JM, Kochar B, Tovar A, Israel JW, Robinson A, Gipson GR, Schaner MS, Herfarth HH, Sartor RB, McGovern DP, Rahbar R, Sadiq TS, Koruda MJ, Furey TS, Sheikh SZ. Molecular classification of Crohn's disease reveals two clinically relevant subtypes. Gut. 2016. PMCIDPMCID 5426990.
Steinbach EC, Gipson GR, Sheikh SZ. Induction of murine intestinal inflammation by adoptive transfer of effector CD4+ CD45RB high T cells into immunodeficient mice. Journal of visualized experiments : JoVE. 2015(98). PMCID: PMC4541583
Arthur JC</span, Gharaibeh RZ, Muhlbauer M, Perez-Chanona E, Uronis JM, McCafferty J, Fodor AA, Jobin C. Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer. Nature Communications. 2014;5:4724. PMCID: PMC4155410.
Freemerman AJ, Johnson AR, Sacks GN, Milner JJ, Kirk EL, Troester MA, Macintyre AN, Goraksha-Hicks P, Rathmell JC, Makowski L. Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. The Journal of Biological Chemistry. 2014;289(11):7884-96. PMCID: PMC3953299.
Qin Y, Hamilton JL, Bird MD, Chen MM, Ramirez L, Zahs A, Kovacs EJ, Makowski L. Adipose inflammation and macrophage infiltration after binge ethanol and burn injury. Alcoholism, Clinical and Experimental Research. 2014;38(1):204-13. PMCID: PMC3823749.

Former members listed above: Baron JA (retired), Henning SJ (retiring), Jobn C (moved), Klaenhammer T (retired) Lund PK (moved), Plevy S (moved), Ringel Y (moved)

Member Collaboration 2019
Collaborations between members. The size of the node indicates number of links. The width of connecting lines represents the number of joint publications. members cluster by major research themes: microbiome (red), clinical/translational (blue), regenerative medicine/repair (green).