Publications
The publications listed below were made possible, in part, by use of CGIBD cores.
| Publication Information |
|---|
| Gaber CE, Cotton CC, Eluri S, Lund JL, Farrell TM, Dellon ES. Autoimmune and viral risk factors are associated with achalasia: A case-control study. Neurogastroenterol Motil. 2022 Jul;34(7):e14312. doi: 10.1111/nmo.14312. Epub 2021 Dec 26. PMID: 34957646; PMCID: PMC9232907. |
| Breau KA, Ok MT, Gomez-Martinez I, Burclaff J, Kohn NP, Magness ST. Efficient transgenesis and homology-directed gene targeting in monolayers of primary human small intestinal and colonic epithelial stem cells. Stem Cell Reports. 2022 Jun 14;17(6):1493-1506. doi: 10.1016/j.stemcr.2022.04.005. Epub 2022 May 5. PMID: 35523179; PMCID: PMC9213823. |
| Boger KD, Sheridan AE, Ziegler AL, Blikslager AT. Mechanisms and modeling of wound repair in the intestinal epithelium. Tissue Barriers. 2022 Jun 11:2087454. doi: 10.1080/21688370.2022.2087454. Epub ahead of print. PMID: 35695206. |
| Kochar B, Pate V, Kappelman MD, Long MD, Ananthakrishnan AN, Chan AT, Sandler RS. Vedolizumab Is Associated With a Lower Risk of Serious Infections Than Anti- Tumor Necrosis Factor Agents in Older Adults. Clin Gastroenterol Hepatol. 2022 Jun;20(6):1299-1305.e5. doi: 10.1016/j.cgh.2021.08.047. Epub 2021 Sep 3. PMID: 34481954; PMCID: PMC8891388. |
| Hoffner O'Connor M, Berglind A, Kennedy Ng MM, Keith BP, Lynch ZJ, Schaner MR, Steinbach EC, Herzog J, Trad OK, Jeck WR, Arthur JC, Simon JM, Sartor RB, Furey TS, Sheikh SZ. BET Protein Inhibition Regulates Macrophage Chromatin Accessibility and Microbiota-Dependent Colitis. Front Immunol. 2022 Mar 24;13:856966. doi: 10.3389/fimmu.2022.856966. PMID: 35401533; PMCID: PMC8988134. |
| Vemuri R, Ruggiero A, Whitfield JM, Dugan GO, Cline JM, Block MR, Guo H, Kavanagh K. Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates. Am J Physiol Heart Circ Physiol. 2022 Mar 1;322(3):H474-H485. doi: 10.1152/ajpheart.00530.2021. Epub 2022 Feb 11. PMID: 35148233; PMCID: PMC8897002. |
| Brocke SA, Billings GT, Taft-Benz S, Alexis NE, Heise MT, Jaspers I. Woodsmoke particle exposure prior to SARS-CoV-2 infection alters antiviral response gene expression in human nasal epithelial cells in a sex-dependent manner. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L479-L494. doi: 10.1152/ajplung.00362.2021. Epub 2022 Feb 2. PMID: 35107034; PMCID: PMC8917918. |
| Lieber SR, Kim HP, Baldelli L, Nash R, Teal R, Magee G, Desai CS, Loiselle MM, Lee SC, Singal AG, Marrero JA, Barritt AS 4th, Evon DM. Early Survivorship After Liver Transplantation: A Qualitative Study Identifying Challenges in Recovery From the Patient and Caregiver Perspective. Liver Transpl. 2022 Mar;28(3):422-436. doi: 10.1002/lt.26303. Epub 2021 Oct 21. PMID: 34529886. |
| Long MD, Siegel CA, Abraham BP, Chiorean M, Mahadevan U. Day Care Attendance and Infectious Complications in Children Born to Mothers With Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2022 Mar;20(3):706-708.e1. doi: 10.1016/j.cgh.2021.02.003. Epub 2021 Feb 4. PMID: 33549864. |
| Peery AF, Crockett SD, Murphy CC, Jensen ET, Kim HP, Egberg MD, Lund JL, Moon AM, Pate V, Barnes EL, Schlusser CL, Baron TH, Shaheen NJ, Sandler RS. Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2021. Gastroenterology. 2022 Feb;162(2):621-644. doi: 10.1053/j.gastro.2021.10.017. Epub 2021 Oct 19. PMID: 34678215. |
| Loeser RF, Arbeeva L, Kelley K, Fodor AA, Sun S, Ulici V, Longobardi L, Cui Y, Stewart DA, Sumner SJ, Azcarate-Peril MA, Sartor RB, Carroll IM, Renner JB, Jordan JM, Nelson AE. Association of Increased Serum Lipopolysaccharide, But Not Microbial Dysbiosis, With Obesity-Related Osteoarthritis. Arthritis Rheumatol. 2022 Feb;74(2):227-236. doi: 10.1002/art.41955. Epub 2022 Jan 4. PMID: 34423918; PMCID: PMC8795472. |
| Gaber CE, Eluri S, Cotton CC, Strassle PD, Farrell TM, Lund JL, Dellon ES. Epidemiologic and Economic Burden of Achalasia in the United States. Clin Gastroenterol Hepatol. 2022 Feb;20(2):342-352.e5. doi: 10.1016/j.cgh.2021.02.035. Epub 2021 Feb 27. PMID: 33652152; PMCID: PMC8390595. |
| Eluri S, Paterson A, Lauren BN, O'Donovan M, Bhandari P, di Pietro M, Lee M, Haidry R, Lovat L, Ragunath K, Hur C, Fitzgerald RC, Shaheen NJ. Utility and Cost-Effectiveness of a Nonendoscopic Approach to Barrett's Esophagus Surveillance After Endoscopic Therapy. Clin Gastroenterol Hepatol. 2022 Feb;20(2):e51-e63. doi: 10.1016/j.cgh.2021.02.013. Epub 2021 Feb 10. PMID: 33581357; PMCID: PMC8352994. |
| Lim C, Dismuke T, Malawsky D, Ramsey JD, Hwang D, Godfrey VL, Kabanov AV, Gershon TR, Sokolsky-Papkov M. Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq-guided combination with sapanisertib. Sci Adv. 2022 Jan 28;8(4):eabl5838. doi: 10.1126/sciadv.abl5838. Epub 2022 Jan 26. PMID: 35080986; PMCID: PMC8791615. |
| Xiao X, Sarma S, Menegatti S, Crook N, Magness ST, Hall CK. In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A. ACS Chem Biol. 2022 Jan 21;17(1):118-128. doi: 10.1021/acschembio.1c00743. Epub 2021 Dec 29. PMID: 34965093. |
| Peery AF, Keku TO, Galanko JA, Sandler RS. Colonic Diverticulosis Is Not Associated With Painful Abdominal Symptoms in a US Population. Gastro Hep Adv. 2022;1(4):659-665. doi: 10.1016/j.gastha.2022.04.001. Epub 2022 Apr 29. PMID: 35821706; PMCID: PMC9273073. |
| Gomez-Martinez I, Bliton RJ, Breau KA, Czerwinski MJ, Williamson IA, Wen J, Rawls JF, Magness ST. A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export. Cell Mol Gastroenterol Hepatol. 2022;14(2):409-434. doi: 10.1016/j.jcmgh.2022.04.009. Epub 2022 Apr 28. PMID: 35489715; PMCID: PMC9305019. |
| Burclaff J, Bliton RJ, Breau KA, Ok MT, Gomez-Martinez I, Ranek JS, Bhatt AP, Purvis JE, Woosley JT, Magness ST. A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics. Cell Mol Gastroenterol Hepatol. 2022;13(5):1554-1589. doi: 10.1016/j.jcmgh.2022.02.007. Epub 2022 Feb 15. PMID: 35176508; PMCID: PMC9043569. |
| Sandler RS, Hansen JJ, Peery AF, Woosley JT, Galanko JA, Keku TO. Intraepithelial and Lamina Propria Lymphocytes Do Not Correlate With Symptoms or Exposures in Microscopic Colitis. Clin Transl Gastroenterol. 2022 Jan 1;13(3):e00467. doi: 10.14309/ctg.0000000000000467. PMID: 35166714; PMCID: PMC8963857. |
| Figueiredo JC, Gresham G, Barry EL, Mott LA, Passarelli MN, Bradshaw PT, Anderson CW, Baron JA. Circulating Sex Hormones and Risk of Colorectal Adenomas and Serrated Lesions in Men. Cancer Epidemiol Biomarkers Prev. 2022 Jan;31(1):293-295. doi: 10.1158/1055-9965.EPI-21-0713. Epub 2021 Nov 10. PMID: 34758968; PMCID: PMC8755601. |
| Rushing BR, McRitchie S, Arbeeva L, Nelson AE, Azcarate-Peril MA, Li YY, Qian Y, Pathmasiri W, Sumner SCJ, Loeser RF. Fecal metabolomics reveals products of dysregulated proteolysis and altered microbial metabolism in obesity-related osteoarthritis. Osteoarthritis Cartilage. 2022 Jan;30(1):81-91. doi: 10.1016/j.joca.2021.10.006. Epub 2021 Oct 28. PMID: 34718137; PMCID: PMC8712415. |
| Shazib MA, Byrd KM, Gulati AS. Diagnosis and Management of Oral Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2022 Jan 1;74(1):7-12. doi: 10.1097/MPG.0000000000003302. PMID: 34560727; PMCID: PMC8714692. |
| Erwin SJ, Blikslager AT, Ziegler AL. Age-Dependent Intestinal Repair: Implications for Foals with Severe Colic. Animals (Basel). 2021 Nov 23;11(12):3337. doi: 10.3390/ani11123337. PMID: 34944114; PMCID: PMC8697879. |
| Stewart AS, Schaaf CR, Luff JA, Freund JM, Becker TC, Tufts SR, Robertson JB, Gonzalez LM. HOPX+ injury-resistant intestinal stem cells drive epithelial recovery after severe intestinal ischemia. Am J Physiol Gastrointest Liver Physiol. 2021 Nov 1;321(5):G588-G602. doi: 10.1152/ajpgi.00165.2021. Epub 2021 Sep 22. PMID: 34549599; PMCID: PMC8616590. |
| Sandler RS, Keku TO, Woosley JT, Galanko JA, Peery AF. Medication use and microscopic colitis. Aliment Pharmacol Ther. 2021 Nov;54(9):1193-1201. doi: 10.1111/apt.16594. Epub 2021 Sep 12. PMID: 34514632; PMCID: PMC8511165. |
| Egberg MD, Galanko JA, Banegas M, Roberson M, Strassle PD, Phillips M, Kappelman MD. Obesity Increases the Risk of Hospital Readmission Following Intestinal Surgery for Children With Crohn Disease. J Pediatr Gastroenterol Nutr. 2021 Nov 1;73(5):620-625. doi: 10.1097/MPG.0000000000003251. PMID: 34321423; PMCID: PMC8542591. |
| Wang J, Bleich RM, Zarmer S, Zhang S, Dogan B, Simpson KW, Arthur JC. Long- read sequencing to interrogate strain-level variation among adherent-invasive Escherichia coli isolated from human intestinal tissue. PLoS One. 2021 Oct 28;16(10):e0259141. doi: 10.1371/journal.pone.0259141. PMID: 34710159; PMCID: PMC8553045. |
| Borren NZ, Long MD, Sandler RS, Ananthakrishnan AN. Longitudinal Trajectory of Fatigue in Patients With Inflammatory Bowel Disease: A Prospective Study. Inflamm Bowel Dis. 2021 Oct 20;27(11):1740-1746. doi: 10.1093/ibd/izaa338. PMID: 33367749; PMCID: PMC8528141. |
| Barnes EL, Kappelman MD, Zhang X, Long MD, Sandler RS, Herfarth HH. Patients With Pouchitis Demonstrate a Significant Cost Burden in the First Two Years After Ileal Pouch-Anal Anastomosis. Clin Gastroenterol Hepatol. 2021 Oct 2:S1542-3565(21)01052-1. doi: 10.1016/j.cgh.2021.09.037. Epub ahead of print. PMID: 34610443; PMCID: PMC8975897. |
| Zhang W, Lanzoni G, Hani H, Overi D, Cardinale V, Simpson S, Pitman W, Allen A, Yi X, Wang X, Gerber D, Prestwich G, Lozoya O, Gaudio E, Alvaro D, Tokaz D, Dominguez-Bendala J, Adin C, Piedrahita J, Mathews K, Sethupathy P, Carpino G, He Z, Wauthier E, Reid LM. Patch grafting, strategies for transplantation of organoids into solid organs such as liver. Biomaterials. 2021 Oct;277:121067. doi: 10.1016/j.biomaterials.2021.121067. Epub 2021 Aug 25. PMID: 34517276; PMCID: PMC8826591. |
| Kim HP, Edwards A, Reeve BB, Golin CE, Evon DM. Symptoms and functioning improve after chronic hepatitis C cure as assessed by the Memorial Symptom Assessment Scale and PROMIS measures. J Viral Hepat. 2021 Oct;28(10):1491-1495. doi: 10.1111/jvh.13561. Epub 2021 Jul 17. PMID: 34185937; PMCID: PMC8458231. |
| Sandler RS, Davidson NO, Monga SP, Rockey DC. Silvio O. Conte Digestive Disease Research Core Centers-Connecting People, Creating Opportunities, Developing Careers. Gastroenterology. 2021 Oct;161(4):1085-1089. doi: 10.1053/j.gastro.2021.06.054. Epub 2021 Jun 24. PMID: 34175277; PMCID: PMC8463423. |
| Alcedo KP, Bowser JL, Snider NT. The elegant complexity of mammalian ecto-5'-nucleotidase (CD73). Trends Cell Biol. 2021 Oct;31(10):829-842. doi: 10.1016/j.tcb.2021.05.008. Epub 2021 Jun 8. PMID: 34116887; PMCID: PMC8448938. |
| Lieber SR, Kim HP, Baldelli L, Nash R, Teal R, Magee G, Loiselle MM, Desai CS, Lee SC, Singal AG, Marrero JA, Barritt AS 4th, Evon DM. What Survivorship Means to Liver Transplant Recipients: Qualitative Groundwork for a Survivorship Conceptual Model. Liver Transpl. 2021 Oct;27(10):1454-1467. doi: 10.1002/lt.26088. Epub 2021 Jul 31. PMID: 33942480. |
| Reed CC, Genta RM, Youngblood BA, Wechsler JB, Dellon ES. Mast Cell and Eosinophil Counts in Gastric and Duodenal Biopsy Specimens From Patients With and Without Eosinophilic Gastroenteritis. Clin Gastroenterol Hepatol. 2021 Oct;19(10):2102-2111. doi: 10.1016/j.cgh.2020.08.013. Epub 2020 Aug 12. PMID: 32801015; PMCID: PMC7878575. |
| McQueen BE, Kollipara A, Gyorke CE, Andrews CW Jr, Ezzell A, Darville T, Nagarajan UM. Reduced Uterine Tissue Damage during Chlamydia muridarum Infection in TREM-1,3-Deficient Mice. Infect Immun. 2021 Sep 16;89(10):e0007221. doi: 10.1128/IAI.00072-21. Epub 2021 Jun 14. PMID: 34125599; PMCID: PMC8445178. |
| Aygün N, Elwell AL, Liang D, Lafferty MJ, Cheek KE, Courtney KP, Mory J, Hadden-Ford E, Krupa O, de la Torre-Ubieta L, Geschwind DH, Love MI, Stein JL. Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis. Am J Hum Genet. 2021 Sep 2;108(9):1647-1668. doi: 10.1016/j.ajhg.2021.07.011. Epub 2021 Aug 19. PMID: 34416157; PMCID: PMC8456186. |
| Oeler K, Hill D, Oldenburg A. OCT particle tracking velocimetry of biofluids in a microparallel plate strain induction chamber. J Biomed Opt. 2021 Sep;26(9):096005. doi: 10.1117/1.JBO.26.9.096005. PMID: 34528428; PMCID: PMC8441543. |
| Lewis JD, Sandler RS, Brotherton C, Brensinger C, Li H, Kappelman MD, Daniel SG, Bittinger K, Albenberg L, Valentine JF, Hanson JS, Suskind DL, Meyer A, Compher CW, Bewtra M, Saxena A, Dobes A, Cohen BL, Flynn AD, Fischer M, Saha S, Swaminath A, Yacyshyn B, Scherl E, Horst S, Curtis JR, Braly K, Nessel L, McCauley M, McKeever L, Herfarth H; DINE-CD Study Group. A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults With Crohn's Disease. Gastroenterology. 2021 Sep;161(3):837-852.e9. doi: 10.1053/j.gastro.2021.05.047. Epub 2021 May 27. PMID: 34052278; PMCID: PMC8396394. |
| Cotton CC, Betancourt R, Randall C, Perjar I, Bookhout C, Woosley JT, Shaheen NJ, Dellon ES. A Model Using Clinical and Endoscopic Characteristics Identifies Patients at Risk for Eosinophilic Esophagitis According to Updated Diagnostic Guidelines. Clin Gastroenterol Hepatol. 2021 Sep;19(9):1824-1834.e2. doi: 10.1016/j.cgh.2020.06.068. Epub 2020 Jul 4. PMID: 32634625; PMCID: PMC7779708. |
| Aureille J, Pezet M, Pernet L, Mazzega J, Grichine A, Guilluy C, Dolega ME. Cell fluorescence photoactivation as a method to select and study cellular subpopulations grown in mechanically heterogeneous environments. Mol Biol Cell. 2021 Aug 1;32(16):1409-1416. doi: 10.1091/mbc.E20-10-0676. Epub 2021 Jun 16. PMID: 34133212; PMCID: PMC8351743. |
| Barnes EL, Herfarth HH, Kappelman MD, Zhang X, Lightner A, Long MD, Sandler RS. Incidence, Risk Factors, and Outcomes of Pouchitis and Pouch-Related Complications in Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2021 Aug;19(8):1583-1591.e4. doi: 10.1016/j.cgh.2020.06.035. Epub 2020 Jun 22. PMID: 32585362; PMCID: PMC8552292. |
| Guadamuro L, Azcárate-Peril MA, Tojo R, Mayo B, Delgado S. Impact of Dietary Isoflavone Supplementation on the Fecal Microbiota and Its Metabolites in Postmenopausal Women. Int J Environ Res Public Health. 2021 Jul 27;18(15):7939. doi: 10.3390/ijerph18157939. PMID: 34360231; PMCID: PMC8345437. |
| Sun S, Zhu X, Huang X, Murff HJ, Ness RM, Seidner DL, Sorgen AA, Blakley IC, Yu C, Dai Q, Azcarate-Peril MA, Shrubsole MJ, Fodor AA. On the robustness of inference of association with the gut microbiota in stool, rectal swab and mucosal tissue samples. Sci Rep. 2021 Jul 21;11(1):14828. doi: 10.1038/s41598-021-94205-5. PMID: 34290321; PMCID: PMC8295290. |
| Hermes DJ, Yadav-Samudrala BJ, Xu C, Paniccia JE, Meeker RB, Armstrong ML, Reisdorph N, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Lysle DT, Fitting S. GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration. Exp Neurol. 2021 Jul;341:113699. doi: 10.1016/j.expneurol.2021.113699. Epub 2021 Mar 15. PMID: 33736974; PMCID: PMC8984429. |
| Lemasters JJ. Metabolic implications of non-electrogenic ATP/ADP exchange in cancer cells: A mechanistic basis for the Warburg effect. Biochim Biophys Acta Bioenerg. 2021 Jul 1;1862(7):148410. doi: 10.1016/j.bbabio.2021.148410. Epub 2021 Mar 13. PMID: 33722515; PMCID: PMC8096716. |
| Toyonaga T, Araba KC, Kennedy MM, Keith BP, Wolber EA, Beasley C, Steinbach EC, Schaner MR, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Kapadia MR, Guillem JG, Gulati AS, Sethupathy P, Furey TS, Ehre C, Sheikh SZ. Increased colonic expression of ACE2 associates with poor prognosis in Crohn's disease. Sci Rep. 2021 Jun 29;11(1):13533. doi: 10.1038/s41598-021-92979-2. PMID: 34188154; PMCID: PMC8241995. |
| Rose EC, Odle J, Blikslager AT, Ziegler AL. Probiotics, Prebiotics and Epithelial Tight Junctions: A Promising Approach to Modulate Intestinal Barrier Function. Int J Mol Sci. 2021 Jun 23;22(13):6729. doi: 10.3390/ijms22136729. PMID: 34201613; PMCID: PMC8268081. |
| Lopez LR, Barlogio CJ, Broberg CA, Wang J, Arthur JC. A nadA Mutation Confers Nicotinic Acid Auxotrophy in Pro-carcinogenic Intestinal Escherichia coli NC101. Front Microbiol. 2021 Jun 2;12:670005. doi: 10.3389/fmicb.2021.670005. PMID: 34149655; PMCID: PMC8207962. |
| Carlson AL, Xia K, Azcarate-Peril MA, Rosin SP, Fine JP, Mu W, Zopp JB, Kimmel MC, Styner MA, Thompson AL, Propper CB, Knickmeyer RC. Infant gut microbiome composition is associated with non-social fear behavior in a pilot study. Nat Commun. 2021 Jun 2;12(1):3294. doi: 10.1038/s41467-021-23281-y. PMID: 34078892; PMCID: PMC8172562. |
| Slifer ZM, Krishnan BR, Madan J, Blikslager AT. Larazotide acetate: a pharmacological peptide approach to tight junction regulation. Am J Physiol Gastrointest Liver Physiol. 2021 Jun 1;320(6):G983-G989. doi: 10.1152/ajpgi.00386.2020. Epub 2021 Apr 21. PMID: 33881350. |
| Gaber CE, Kinlaw AC, Edwards JK, Lund JL, Stürmer T, Peacock Hinton S, Pate V, Bartelt LA, Sandler RS, Peery AF. Comparative Effectiveness and Harms of Antibiotics for Outpatient Diverticulitis : Two Nationwide Cohort Studies. Ann Intern Med. 2021 Jun;174(6):737-746. doi: 10.7326/M20-6315. Epub 2021 Feb 23. PMID: 33617725; PMCID: PMC9035276. |
| van der Lelie D, Oka A, Taghavi S, Umeno J, Fan TJ, Merrell KE, Watson SD, Ouellette L, Liu B, Awoniyi M, Lai Y, Chi L, Lu K, Henry CS, Sartor RB. Rationally designed bacterial consortia to treat chronic immune-mediated colitis and restore intestinal homeostasis. Nat Commun. 2021 May 28;12(1):3105. doi: 10.1038/s41467-021-23460-x. PMID: 34050144; PMCID: PMC8163890. |
| Malawsky DS, Weir SJ, Ocasio JK, Babcock B, Dismuke T, Cleveland AH, Donson AM, Vibhakar R, Wilhelmsen K, Gershon TR. Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile. Commun Biol. 2021 May 21;4(1):616. doi: 10.1038/s42003-021-02099-w. PMID: 34021242; PMCID: PMC8139976. |
| Durmusoglu D, Al'Abri IS, Collins SP, Cheng J, Eroglu A, Beisel CL, Crook N. In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii. ACS Synth Biol. 2021 May 21;10(5):1039-1052. doi: 10.1021/acssynbio.0c00562. Epub 2021 Apr 12. PMID: 33843197. |
| Jahnke JR, Roach J, Azcarate-Peril MA, Thompson AL. Maternal precarity and HPA axis functioning shape infant gut microbiota and HPA axis development in humans. PLoS One. 2021 May 20;16(5):e0251782. doi: 10.1371/journal.pone.0251782. PMID: 34015045; PMCID: PMC8136730. |
| Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE, Mascenik T, Yin WN, Barbosa Cardenas SM, O'Neal YK, Minnick CE, Chua M, Quinney NL, Gentzsch M, Anderson CW, Ghio A, Matsui H, Nagase T, Ostrowski LE, Grubb BR, Olsen JC, Randell SH, Stripp BR, Tata PR, O'Neal WK, Boucher RC. Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia. Am J Respir Crit Care Med. 2021 May 15;203(10):1275-1289. doi: 10.1164/rccm.202008-3198OC. PMID: 33321047; PMCID: PMC8456462. |
| Bhatt AP, Sartor RB. 'Bugs on drugs': implications for gut health. Nat Rev Gastroenterol Hepatol. 2021 May;18(5):287-288. doi: 10.1038/s41575-021-00437-1. PMID: 33692569; PMCID: PMC8610095. |
| Slifer ZM, Hernandez L, Pridgen TA, Carlson AR, Messenger KM, Madan J, Krishnan BR, Laumas S, Blikslager AT. Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions. PLoS One. 2021 Apr 22;16(4):e0250165. doi: 10.1371/journal.pone.0250165. PMID: 33886649; PMCID: PMC8061941. |
| Enomoto H, Yeatts J, Carbajal L, Krishnan BR, Madan JP, Laumas S, Blikslager AT, Messenger KM. In vivo assessment of a delayed release formulation of larazotide acetate indicated for celiac disease using a porcine model. PLoS One. 2021 Apr 12;16(4):e0249179. doi: 10.1371/journal.pone.0249179. PMID: 33844694; PMCID: PMC8041193. |
| Serper M, Evon DM, Amador J, Stewart PW, Sarkar S, Lok AS, Sterling RK, Reeve BB, Golin CE, Rajender Reddy K, Lim JK, Reau N, Nelson DR, Di Bisceglie AM, Fried MW. Patient-reported outcomes 12 months after hepatitis C treatment with direct-acting antivirals: Results from the PROP UP study. Liver Int. 2021 Apr;41(4):692-704. doi: 10.1111/liv.14781. Epub 2021 Jan 22. PMID: 33387381; PMCID: PMC7969418. |
| Lieber SR, Kim HP, Baldelli L, Evon DM, Teal R, Nash R, Magee G, Desai CS, Gerber D, Serrano P, Shah N, Barritt AS 4th. What Liver Transplant Recipients Want in a Smartphone Intervention to Enhance Recovery: Prototype for the LiveRight Transplant App. Liver Transpl. 2021 Apr;27(4):584-589. doi: 10.1002/lt.25967. Epub 2021 Feb 15. PMID: 33300288. |
| Kochar B, Jiang Y, Long MD. Patients With Inflammatory Bowel Diseases Are at Higher Risk for Meningitis. J Clin Gastroenterol. 2021 Apr 1;55(4):350-354. doi: 10.1097/MCG.0000000000001365. PMID: 32482950; PMCID: PMC7704607. |
| Barnes EL, Kochar B, Herfarth HH, Winter RW, Long MD, Korzenik JR, Quevedo SF, Galanko JA, Koruda M, Kappelman MD, Sandler RS. Creation of a Case-Finding Definition for Identifying Patients With Acute Pouchitis in Administrative Claims Data. Clin Gastroenterol Hepatol. 2021 Apr;19(4):842-844.e1. doi: 10.1016/j.cgh.2020.03.003. Epub 2020 Mar 6. PMID: 32147595. |
| Egberg MD, Phillips M, Galanko JA, Kappelman M. Total Abdominal Colectomies With Proctectomy Are Associated With Higher 30-Day Readmission Rates in Children With Ulcerative Colitis. Inflamm Bowel Dis. 2021 Mar 15;27(4):493-499. doi: 10.1093/ibd/izaa099. PMID: 32426816; PMCID: PMC7957218. |
| Crockett S, Dellon ES, Biggers L, Ernst DA. Use of Patient Abdominal Compression Device Reduces Staff Musculoskeletal Pain Associated With Supporting Colonoscopy: Results From a Randomized Controlled Trial. Gastroenterol Nurs. 2021 Mar-Apr 01;44(2):136-145. doi: 10.1097/SGA.0000000000000550. PMID: 33795622; PMCID: PMC8021235. |
| Mahadevan U, Long MD, Kane SV, Roy A, Dubinsky MC, Sands BE, Cohen RD, Chambers CD, Sandborn WJ; Crohn’s Colitis Foundation Clinical Research Alliance. Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease. Gastroenterology. 2021 Mar;160(4):1131-1139. doi: 10.1053/j.gastro.2020.11.038. Epub 2020 Nov 21. PMID: 33227283; PMCID: PMC7956164. |
| Lee MK, Wyss AB, Carnes MU, Richards M, Parks CG, Beane Freeman LE, Thorne PS, Umbach DM, Azcarate-Peril MA, Peddada SD, London SJ. House dust microbiota in relation to adult asthma and atopy in a US farming population. J Allergy Clin Immunol. 2021 Mar;147(3):910-920. doi: 10.1016/j.jaci.2020.06.013. Epub 2020 Jun 29. PMID: 32615170; PMCID: PMC7770060. |
| Wright BL, Doyle AD, Shim KP, Pai RK, Barshow SM, Horsley-Silva JL, Luo H, Rank MA, Jacobsen EA, Katzka DA, Kita H, Dellon ES. Image Analysis of Eosinophil Peroxidase Immunohistochemistry for Diagnosis of Eosinophilic Esophagitis. Dig Dis Sci. 2021 Mar;66(3):775-783. doi: 10.1007/s10620-020-06230-5. Epub 2020 Apr 4. PMID: 32248390; PMCID: PMC7541435. |
| Byrd KM, Gulati AS. The "Gum-Gut" Axis in Inflammatory Bowel Diseases: A Hypothesis-Driven Review of Associations and Advances. Front Immunol. 2021 Feb 19;12:620124. doi: 10.3389/fimmu.2021.620124. PMID: 33679761; PMCID: PMC7933581. |
| Bierlein M, Hedgespeth BA, Azcarate-Peril MA, Stauffer SH, Gookin JL. Dysbiosis of fecal microbiota in cats with naturally occurring and experimentally induced Tritrichomonas foetus infection. PLoS One. 2021 Feb 19;16(2):e0246957. doi: 10.1371/journal.pone.0246957. PMID: 33606740; PMCID: PMC7894905. |
| Barnes EL, Bauer CM, Sandler RS, Kappelman MD, Long MD. Black and White Patients With Inflammatory Bowel Disease Show Similar Biologic Use Patterns With Medicaid Insurance. Inflamm Bowel Dis. 2021 Feb 16;27(3):364-370. doi: 10.1093/ibd/izaa090. PMID: 32405642; PMCID: PMC7885313. |
| Marler JD, Fujii CA, Galanko JA, Balbierz DJ, Utley DS. Durability of Abstinence After Completing a Comprehensive Digital Smoking Cessation Program Incorporating a Mobile App, Breath Sensor, and Coaching: Cohort Study. J Med Internet Res. 2021 Feb 15;23(2):e25578. doi: 10.2196/25578. PMID: 33482628; PMCID: PMC7920755. |
| Prasher A, Shrivastava R, Dahl D, Sharma-Huynh P, Maturavongsadit P, Pridgen T, Schorzman A, Zamboni W, Ban J, Blikslager A, Dellon ES, Benhabbour SR. Steroid Eluting Esophageal-Targeted Drug Delivery Devices for Treatment of Eosinophilic Esophagitis. Polymers (Basel). 2021 Feb 13;13(4):557. doi: 10.3390/polym13040557. PMID: 33668571; PMCID: PMC7917669. |
| Foley MH, O'Flaherty S, Allen G, Rivera AJ, Stewart AK, Barrangou R, Theriot CM. Lactobacillus bile salt hydrolase substrate specificity governs bacterial fitness and host colonization. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2017709118. doi: 10.1073/pnas.2017709118. PMID: 33526676; PMCID: PMC8017965. |
| Hwang D, Dismuke T, Tikunov A, Rosen EP, Kagel JR, Ramsey JD, Lim C, Zamboni W, Kabanov AV, Gershon TR, Sokolsky-Papkov PhD M. Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity. Nanomedicine. 2021 Feb;32:102345. doi: 10.1016/j.nano.2020.102345. Epub 2020 Nov 28. PMID: 33259959; PMCID: PMC8160025. |
| Rosin S, Xia K, Azcarate-Peril MA, Carlson AL, Propper CB, Thompson AL, Grewen K, Knickmeyer RC. A preliminary study of gut microbiome variation and HPA axis reactivity in healthy infants. Psychoneuroendocrinology. 2021 Feb;124:105046. doi: 10.1016/j.psyneuen.2020.105046. Epub 2020 Nov 12. PMID: 33254059; PMCID: PMC8121098. |
| Venkatratnam A, Douillet C, Topping BC, Shi Q, Addo KA, Ideraabdullah FY, Fry RC, Styblo M. Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring. Arch Toxicol. 2021 Feb;95(2):473-488. doi: 10.1007/s00204-020-02941-w. Epub 2020 Nov 3. PMID: 33145626; PMCID: PMC7878413. |
| Arnold JW, Roach J, Fabela S, Moorfield E, Ding S, Blue E, Dagher S, Magness S, Tamayo R, Bruno-Barcena JM, Azcarate-Peril MA. The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut. Microbiome. 2021 Jan 28;9(1):31. doi: 10.1186/s40168-020-00980-0. Erratum in: Microbiome. 2021 Feb 26;9(1):56. PMID: 33509277; PMCID: PMC7845053. |
| Goh YJ, Barrangou R, Klaenhammer TR. In Vivo Transcriptome of Lactobacillus acidophilus and Colonization Impact on Murine Host Intestinal Gene Expression. mBio. 2021 Jan 26;12(1):e03399-20. doi: 10.1128/mBio.03399-20. PMID: 33500337; PMCID: PMC7858073. |
| Azcarate-Peril MA, Roach J, Marsh A, Chey WD, Sandborn WJ, Ritter AJ, Savaiano DA, Klaenhammer TR. A double-blind, 377-subject randomized study identifies Ruminococcus, Coprococcus, Christensenella, and Collinsella as long-term potential key players in the modulation of the gut microbiome of lactose intolerant individuals by galacto-oligosaccharides. Gut Microbes. 2021 Jan-Dec;13(1):1957536. doi: 10.1080/19490976.2021.1957536. PMID: 34365905; PMCID: PMC8354614. |
| Fan TJ, Goeser L, Lu K, Faith JJ, Hansen JJ. Enterococcus faecalis Glucosamine Metabolism Exacerbates Experimental Colitis. Cell Mol Gastroenterol Hepatol. 2021;12(4):1373-1389. doi: 10.1016/j.jcmgh.2021.06.017. Epub 2021 Jul 8. PMID: 34246809; PMCID: PMC8479252. |
| Glenny EM, Fouladi F, Thomas SA, Bulik-Sullivan EC, Tang Q, Djukic Z, Trillo-Ordonez YS, A Fodor A, Tarantino LM, M Bulik C, M Carroll I. Gut microbial communities from patients with anorexia nervosa do not influence body weight in recipient germ-free mice. Gut Microbes. 2021 Jan-Dec;13(1):1-15. doi: 10.1080/19490976.2021.1897216. PMID: 33769200; PMCID: PMC8007138. |
| Alcedo KP, Rouse MA, Jung GS, Fu D, Minor M, Willcockson HH, Greene KG, Snider NT. CD73 Maintains Hepatocyte Metabolic Integrity and Mouse Liver Homeostasis in a Sex-Dependent Manner. Cell Mol Gastroenterol Hepatol. 2021;12(1):141-157. doi: 10.1016/j.jcmgh.2021.01.016. Epub 2021 Jan 29. PMID: 33516905; PMCID: PMC8082562. |
| Tulasi DY, Castaneda DM, Wager K, Hogan CB, Alcedo KP, Raab JR, Gracz AD. Sox9EGFP Defines Biliary Epithelial Heterogeneity Downstream of Yap Activity. Cell Mol Gastroenterol Hepatol. 2021;11(5):1437-1462. doi: 10.1016/j.jcmgh.2021.01.009. Epub 2021 Jan 23. PMID: 33497866; PMCID: PMC8024983. |
| Oka A, Liu B, Herzog JW, Sartor RB. B-Cell Commitment to IL-10 Production: The VertX Il10egfp Mouse. Methods Mol Biol. 2021;2270:341-358. doi: 10.1007/978-1-0716-1237-8_19. PMID: 33479908; PMCID: PMC8312906. |
| Montrose DC, Nishiguchi R, Basu S, Staab HA, Zhou XK, Wang H, Meng L, Johncilla M, Cubillos-Ruiz JR, Morales DK, Wells MT, Simpson KW, Zhang S, Dogan B, Jiao C, Fei Z, Oka A, Herzog JW, Sartor RB, Dannenberg AJ. Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis. Cell Mol Gastroenterol Hepatol. 2021;11(2):525-550. doi: 10.1016/j.jcmgh.2020.09.008. Epub 2020 Sep 20. PMID: 32961355; PMCID: PMC7797369. |
| Safroneeva E, Cotton CC, Schoepfer AM, Zwahlen M, Woosley JT, Dellon ES. Dilation Modifies Association Between Symptoms and Esophageal Eosinophilia in Adult Patients With Eosinophilic Esophagitis. Am J Gastroenterol. 2020 Dec;115(12):2098-2102. doi: 10.14309/ajg.0000000000000957. PMID: 33009060; PMCID: PMC7710608. |
| Lieber SR, Heller BJ, Howard CW, Sandler RS, Crockett S, Barritt AS 4th. Complications Associated With Anesthesia Services in Endoscopic Procedures Among Patients With Cirrhosis. Hepatology. 2020 Dec;72(6):2109-2118. doi: 10.1002/hep.31224. PMID: 32153048; PMCID: PMC7483314. |
| Shahir NM, Wang JR, Wolber EA, Schaner MS, Frank DN, Ir D, Robertson CE, Chaumont N, Sadiq TS, Koruda MJ, Rahbar R, Nix BD, Newberry RD, Sartor RB, Sheikh SZ, Furey TS. Crohn's Disease Differentially Affects Region-Specific Composition and Aerotolerance Profiles of Mucosally Adherent Bacteria. Inflamm Bowel Dis. 2020 Nov 19;26(12):1843-1855. doi: 10.1093/ibd/izaa103. PMID: 32469069; PMCID: PMC7676424. |
| Marsh AJ, Chandrashekhar K, Ng S, Roach J, Magness ST, Azcarate-Peril MA. Genome Sequence of Eubacterium callanderi AMC0717, Isolated from the Colonic Mucosa of an 11-Year-Old Organ Donor. Microbiol Resour Announc. 2020 Nov 12;9(46):e00995-20. doi: 10.1128/MRA.00995-20. PMID: 33184159; PMCID: PMC7660998. |
| Marsh AJ, Chandrashekhar K, Ng S, Roach J, Magness ST, Azcarate-Peril MA. Genome Sequence of Citrobacter freundii AMC0703, Isolated from the Intestinal Lumen of an 11-Year-Old Organ Donor. Microbiol Resour Announc. 2020 Nov 12;9(46):e00994-20. doi: 10.1128/MRA.00994-20. PMID: 33184158; PMCID: PMC7660997. |
| Ziegler AL, Blikslager AT. Sparing the gut: COX-2 inhibitors herald a new era for treatment of horses with surgical colic. Equine Vet Educ. 2020 Nov;32(11):611-616. doi: 10.1111/eve.13189. Epub 2019 Oct 4. PMID: 34305336; PMCID: PMC8297937. |
| Gonzalez LM, Baker WT, Hughes FE, Blikslager AT, Fogle CA. Comparison of histomorphometric characteristics of dorsal colon and pelvic flexure biopsy specimens obtained from horses with large colon volvulus that underwent resection. Am J Vet Res. 2020 Nov;81(11):899-903. doi: 10.2460/ajvr.81.11.899. PMID: 33107753; PMCID: PMC8972794. |
| Marler JD, Fujii CA, Wong KS, Galanko JA, Balbierz DJ, Utley DS. Assessment of a Personal Interactive Carbon Monoxide Breath Sensor in People Who Smoke Cigarettes: Single-Arm Cohort Study. J Med Internet Res. 2020 Oct 2;22(10):e22811. doi: 10.2196/22811. PMID: 32894829; PMCID: PMC7568220. |
| Ziegler AL, Pridgen TA, Blikslager AT. Environmental stressors affect intestinal permeability and repair responses in a pig intestinal ischemia model. Tissue Barriers. 2020 Oct 1;8(4):1832421. doi: 10.1080/21688370.2020.1832421. Epub 2020 Oct 26. PMID: 33100144; PMCID: PMC7714481. |
| Whittington HD, Singh M, Ta C, Azcárate-Peril MA, Bruno-Bárcena JM. Accelerated Biodegradation of the Agrochemical Ametoctradin by Soil-Derived Microbial Consortia. Front Microbiol. 2020 Aug 25;11:1898. doi: 10.3389/fmicb.2020.01898. PMID: 32982997; PMCID: PMC7477900. |
| Holmes ZC, Silverman JD, Dressman HK, Wei Z, Dallow EP, Armstrong SC, Seed PC, Rawls JF, David LA. Short-Chain Fatty Acid Production by Gut Microbiota from Children with Obesity Differs According to Prebiotic Choice and Bacterial Community Composition. mBio. 2020 Aug 11;11(4):e00914-20. doi: 10.1128/mBio.00914-20. PMID: 32788375; PMCID: PMC7439474. |
| Laudermilk LT, Tovar A, Homstad AK, Thomas JM, McFadden KM, Tune MK, Cowley DO, Mock JR, Ideraabdullah F, Kelada SNP. Baseline and innate immune response characterization of a Zfp30 knockout mouse strain. Mamm Genome. 2020 Aug;31(7-8):205-214. doi: 10.1007/s00335-020-09847-z. Epub 2020 Aug 29. PMID: 32860515; PMCID: PMC7486244. |
| Thomas S. An engraved surface induces weak adherence and high proliferation of nonadherent cells and microorganisms during culture. Biotechniques. 2020 Aug;69(2):113-125. doi: 10.2144/btn-2020-0022. Epub 2020 Jun 12. PMID: 32527143. |
| Peery AF, Keku TO, Galanko JA, Sandler RS. Sex and Race Disparities in Diverticulosis Prevalence. Clin Gastroenterol Hepatol. 2020 Aug;18(9):1980-1986. doi: 10.1016/j.cgh.2019.10.022. Epub 2019 Oct 18. PMID: 31634580; PMCID: PMC7165024. |
| Barnes EL, Jiang Y, Kappelman MD, Long MD, Sandler RS, Kinlaw AC, Herfarth HH. Decreasing Colectomy Rate for Ulcerative Colitis in the United States Between 2007 and 2016: A Time Trend Analysis. Inflamm Bowel Dis. 2020 Jul 17;26(8):1225-1231. doi: 10.1093/ibd/izz247. PMID: 31634390; PMCID: PMC7365804. |
| Fouladi F, Glenny EM, Bulik-Sullivan EC, Tsilimigras MCB, Sioda M, Thomas SA, Wang Y, Djukic Z, Tang Q, Tarantino LM, Bulik CM, Fodor AA, Carroll IM. Sequence variant analysis reveals poor correlations in microbial taxonomic abundance between humans and mice after gnotobiotic transfer. ISME J. 2020 Jul;14(7):1809-1820. doi: 10.1038/s41396-020-0645-z. Epub 2020 Apr 20. PMID: 32313261; PMCID: PMC7305193. |
| Villa MM, Bloom RJ, Silverman JD, Durand HK, Jiang S, Wu A, Dallow EP, Huang S, You L, David LA. Interindividual Variation in Dietary Carbohydrate Metabolism by Gut Bacteria Revealed with Droplet Microfluidic Culture. mSystems. 2020 Jun 30;5(3):e00864-19. doi: 10.1128/mSystems.00864-19. PMID: 32606031; PMCID: PMC7329328. |
| Aliverti E, Tilson JL, Filer DL, Babcock B, Colaneri A, Ocasio J, Gershon TR, Wilhelmsen KC, Dunson DB. Projected t-SNE for batch correction. Bioinformatics. 2020 Jun 1;36(11):3522-3527. doi: 10.1093/bioinformatics/btaa189. PMID: 32176244; PMCID: PMC7267829. |
| Whelan KA, Godwin BC, Wilkins B, Elci OU, Benitez A, DeMarshall M, Sharma M, Gross J, Klein-Szanto AJ, Liacouras CA, Dellon ES, Spergel JM, Falk GW, Muir AB, Nakagawa H. Persistent Basal Cell Hyperplasia Is Associated With Clinical and Endoscopic Findings in Patients With Histologically Inactive Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2020 Jun;18(7):1475-1482.e1. doi: 10.1016/j.cgh.2019.08.055. Epub 2019 Sep 6. PMID: 31499251; PMCID: PMC7058491. |
| Dellon ES, Woosley JT, Arrington A, McGee SJ, Covington J, Moist SE, Gebhart JH, Galanko JA, Baron JA, Shaheen NJ. Rapid Recurrence of Eosinophilic Esophagitis Activity After Successful Treatment in the Observation Phase of a Randomized, Double-Blind, Double-Dummy Trial. Clin Gastroenterol Hepatol. 2020 Jun;18(7):1483-1492.e2. doi: 10.1016/j.cgh.2019.08.050. Epub 2019 Sep 6. PMID: 31499249; PMCID: PMC7058486. |
| Li F, Bahnson EM, Wilder J, Siletzky R, Hagaman J, Nickekeit V, Hiller S, Ayesha A, Feng L, Levine JS, Takahashi N, Maeda-Smithies N. Oral high dose vitamin B12 decreases renal superoxide and post-ischemia/reperfusion injury in mice. Redox Biol. 2020 May;32:101504. doi: 10.1016/j.redox.2020.101504. Epub 2020 Mar 10. Erratum in: Redox Biol. 2021 Aug;44:102023. PMID: 32182573; PMCID: PMC7078436. |
| Nielsen NR, Rangarajan KV, Mao L, Rockman HA, Caron KM. A murine model of increased coronary sinus pressure induces myocardial edema with cardiac lymphatic dilation and fibrosis. Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H895-H907. doi: 10.1152/ajpheart.00436.2019. Epub 2020 Mar 6. PMID: 32142379; PMCID: PMC7191489. |
| Krüger L, Pridgen TA, Taylor ER, Garman KS, Blikslager AT. Lubiprostone protects esophageal mucosa from acid injury in porcine esophagus. Am J Physiol Gastrointest Liver Physiol. 2020 Apr 1;318(4):G613-G623. doi: 10.1152/ajpgi.00086.2019. Epub 2020 Feb 18. PMID: 32068440; PMCID: PMC7191458. |
| Serper M, Evon DM, Stewart PW, Lok AS, Amador J, Reeve BB, Golin CE, Fried MW, Reddy KR, Sterling RK, Sarkar S, Di Bisceglie AM, Lim JK, Nelson DR, Reau N. Medication Non-adherence in a Prospective, Multi-center Cohort Treated with Hepatitis C Direct-Acting Antivirals. J Gen Intern Med. 2020 Apr;35(4):1011-1020. doi: 10.1007/s11606-019-05394-9. Epub 2019 Oct 28. PMID: 31659661; PMCID: PMC7174473. |
| Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, Sartor RB, Gharaibeh RZ, Bultman SJ, Redinbo MR. Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7374-7381. doi: 10.1073/pnas.1918095117. Epub 2020 Mar 13. PMID: 32170007; PMCID: PMC7132129. |
| Leatherwood WH, Bortner BA, Draeger RW, Dahners LE, Rubin J, Weinhold PS. Evaluation of zoledronate, cytochalasin-D, and desferrioxamine on osseointegration in an intra-medullary femoral implant model. J Musculoskelet Neuronal Interact. 2020 Mar 3;20(1):121-127. PMID: 32131376; PMCID: PMC7104579. |
| Ervin SM, Ramanan SV, Bhatt AP. Relationship Between the Gut Microbiome and Systemic Chemotherapy. Dig Dis Sci. 2020 Mar;65(3):874-884. doi: 10.1007/s10620-020-06119-3. PMID: 32026181; PMCID: PMC7046092. |
| Oka A, Sartor RB. Microbial-Based and Microbial-Targeted Therapies for Inflammatory Bowel Diseases. Dig Dis Sci. 2020 Mar;65(3):757-788. doi: 10.1007/s10620-020-06090-z. PMID: 32006212; PMCID: PMC7311927. |
| Rogala AR, Oka A, Sartor RB. Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic Mice. Front Immunol. 2020 Feb 18;11:214. doi: 10.3389/fimmu.2020.00214. PMID: 32133003; PMCID: PMC7040030. |
| Slifer ZM, Blikslager AT. The Integral Role of Tight Junction Proteins in the Repair of Injured Intestinal Epithelium. Int J Mol Sci. 2020 Feb 1;21(3):972. doi: 10.3390/ijms21030972. PMID: 32024112; PMCID: PMC7036844. |
| Liu R, Kang JD, Sartor RB, Sikaroodi M, Fagan A, Gavis EA, Zhou H, Hylemon PB, Herzog JW, Li X, Lippman RH, Gonzalez-Maeso J, Wade JB, Ghosh S, Gurley E, Gillevet PM, Bajaj JS. Neuroinflammation in Murine Cirrhosis Is Dependent on the Gut Microbiome and Is Attenuated by Fecal Transplant. Hepatology. 2020 Feb;71(2):611-626. doi: 10.1002/hep.30827. Epub 2019 Aug 19. PMID: 31220352; PMCID: PMC6923631. |
| Jariwala PB, Pellock SJ, Goldfarb D, Cloer EW, Artola M, Simpson JB, Bhatt AP, Walton WG, Roberts LR, Major MB, Davies GJ, Overkleeft HS, Redinbo MR. Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. ACS Chem Biol. 2020 Jan 17;15(1):217-225. doi: 10.1021/acschembio.9b00788. Epub 2019 Dec 12. PMID: 31774274; PMCID: PMC7321802. |
| Raab JR, Tulasi DY, Wager KE, Morowitz JM, Magness ST, Gracz AD. Quantitative classification of chromatin dynamics reveals regulators of intestinal stem cell differentiation. Development. 2020 Jan 3;147(1):dev181966. doi: 10.1242/dev.181966. PMID: 31862843; PMCID: PMC6983707. |
| Huynh PK, Wilder J, Hiller S, Hagaman J, Takahashi N, Maeda-Smithies N, Li F. Beneficial effects of nicotinamide on hypertensive mice with impaired endothelial nitric oxide function. J Exp Nephrol. 2020;1(1):1-8. PMID: 32905409; PMCID: PMC7470241. |
| Toyonaga T, Steinbach EC, Keith BP, Barrow JB, Schaner MR, Wolber EA, Beasley C, Huling J, Wang Y, Allbritton NL, Chaumont N, Sadiq TS, Koruda MJ, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Shanahan MT, Rahbar R, Furey TS, Sethupathy P, Sheikh SZ. Decreased Colonic Activin Receptor- Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn's Disease. Cell Mol Gastroenterol Hepatol. 2020;10(4):779-796. doi: 10.1016/j.jcmgh.2020.06.005. Epub 2020 Jun 16. PMID: 32561494; PMCID: PMC7502566. |
| Purkayastha BPD, Chan ER, Ravillah D, Ravi L, Gupta R, Canto MI, Wang JS, Shaheen NJ, Willis JE, Chak A, Varadan V, Guda K. Genome-Scale Analysis Identifies Novel Transcript-Variants in Esophageal Adenocarcinoma. Cell Mol Gastroenterol Hepatol. 2020;10(3):652-654.e17. doi: 10.1016/j.jcmgh.2020.04.011. Epub 2020 Apr 25. PMID: 32344180; PMCID: PMC7474160. |
| Plundrich NJ, Smith AR, Borst LB, Snider DB, Käser T, Dellon ES, Blikslager AT, Odle J, Lila MA, Laster SM. Oesophageal eosinophilia accompanies food allergy to hen egg white protein in young pigs. Clin Exp Allergy. 2020 Jan;50(1):95-104. doi: 10.1111/cea.13527. Epub 2019 Nov 26. PMID: 31702085; PMCID: PMC6930966. |
| Camilleri M, Sandler RS, Peery AF. Etiopathogenetic Mechanisms in Diverticular Disease of the Colon. Cell Mol Gastroenterol Hepatol. 2020;9(1):15-32. doi: 10.1016/j.jcmgh.2019.07.007. Epub 2019 Jul 25. PMID: 31351939; PMCID: PMC6881605. |
| Ellermann M, Gharaibeh RZ, Maharshak N, Peréz-Chanona E, Jobin C, Carroll IM, Arthur JC, Plevy SE, Fodor AA, Brouwer CR, Sartor RB. Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice. Gut Microbes. 2020;11(1):32-50. doi: 10.1080/19490976.2019.1599794. Epub 2019 Jun 10. PMID: 31179826; PMCID: PMC6973310. |
| Peery AF, Keil A, Jicha K, Galanko JA, Sandler RS. Association of Obesity With Colonic Diverticulosis in Women. Clin Gastroenterol Hepatol. 2020 Jan;18(1):107-114.e1. doi: 10.1016/j.cgh.2019.04.058. Epub 2019 May 8. PMID: 31077829; PMCID: PMC6842072. |
| Byrd KM, Piehl NC, Patel JH, Huh WJ, Sequeira I, Lough KJ, Wagner BL, Marangoni P, Watt FM, Klein OD, Coffey RJ, Williams SE. Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. Cell Stem Cell. 2019 Dec 5;25(6):814-829.e6. doi: 10.1016/j.stem.2019.11.005. PMID: 31809739; PMCID: PMC6925542. |
| Dellon ES, Guo R, McGee SJ, Hamilton DK, Nicolai E, Covington J, Moist SE, Arrington A, Wright BL, Burks AW, Vickery BP, Kulis M. A Novel Allergen-Specific Immune Signature-Directed Approach to Dietary Elimination in Eosinophilic Esophagitis. Clin Transl Gastroenterol. 2019 Dec;10(12):e00099. doi: 10.14309/ctg.0000000000000099. PMID: 31789931; PMCID: PMC6970559. |
| Eluri S, Perjar I, Betancourt R, Randall C, Raja S, Woosley JT, Shaheen NJ, Dellon ES. Heartburn and dyspepsia symptom severity improves after treatment and correlates with histology in adults with eosinophilic esophagitis. Dis Esophagus. 2019 Nov 13;32(9):doz028. doi: 10.1093/dote/doz028. PMID: 31329864; PMCID: PMC7608739. |
| Valès S, Bacola G, Biraud M, Touvron M, Bessard A, Geraldo F, Dougherty KA, Lashani S, Bossard C, Flamant M, Duchalais E, Marionneau-Lambot S, Oullier T, Oliver L, Neunlist M, Vallette FM, Van Landeghem L. Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis. EBioMedicine. 2019 Nov;49:172-188. doi: 10.1016/j.ebiom.2019.09.045. Epub 2019 Oct 26. PMID: 31662289; PMCID: PMC6945247. |
| Ellermann M, Gharaibeh RZ, Fulbright L, Dogan B, Moore LN, Broberg CA, Lopez LR, Rothemich AM, Herzog JW, Rogala A, Gordon IO, Rieder F, Brouwer CR, Simpson KW, Jobin C, Sartor RB, Arthur JC. Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10-/- Mice. Infect Immun. 2019 Oct 18;87(11):e00587-19. doi: 10.1128/IAI.00587-19. PMID: 31481410; PMCID: PMC6803345. |
| Casadei E, Tacchi L, Lickwar CR, Espenschied ST, Davison JM, Muñoz P, Rawls JF, Salinas I. Commensal Bacteria Regulate Gene Expression and Differentiation in Vertebrate Olfactory Systems Through Transcription Factor REST. Chem Senses. 2019 Oct 17;44(8):615-630. doi: 10.1093/chemse/bjz050. PMID: 31403159; PMCID: PMC6796929. |
| Alcedo KP, Guerrero A, Basrur V, Fu D, Richardson ML, McLane JS, Tsou CC, Nesvizhskii AI, Welling TH, Lebrilla CB, Otey CA, Kim HJ, Omary MB, Snider NT. Tumor-Selective Altered Glycosylation and Functional Attenuation of CD73 in Human Hepatocellular Carcinoma. Hepatol Commun. 2019 Aug 9;3(10):1400-1414. doi: 10.1002/hep4.1410. PMID: 31592495; PMCID: PMC6771166. |
| Aureille J, Buffière-Ribot V, Harvey BE, Boyault C, Pernet L, Andersen T, Bacola G, Balland M, Fraboulet S, Van Landeghem L, Guilluy C. Nuclear envelope deformation controls cell cycle progression in response to mechanical force. EMBO Rep. 2019 Sep;20(9):e48084. doi: 10.15252/embr.201948084. Epub 2019 Aug 1. PMID: 31368207; PMCID: PMC6726894. |
| Barnes EL, Kochar B, Jessup HR, Herfarth HH. The Incidence and Definition of Crohn's Disease of the Pouch: A Systematic Review and Meta-analysis. Inflamm Bowel Dis. 2019 Aug 20;25(9):1474-1480. doi: 10.1093/ibd/izz005. PMID: 30698715; PMCID: PMC6703435. |
| Fan TJ, Goeser L, Naziripour A, Redinbo MR, Hansen JJ. Enterococcus faecalis Gluconate Phosphotransferase System Accelerates Experimental Colitis and Bacterial Killing by Macrophages. Infect Immun. 2019 Jun 20;87(7):e00080-19. doi: 10.1128/IAI.00080-19. PMID: 31036600; PMCID: PMC6589050. |
| Albenberg L, Brensinger CM, Wu Q, Gilroy E, Kappelman MD, Sandler RS, Lewis JD. A Diet Low in Red and Processed Meat Does Not Reduce Rate of Crohn's Disease Flares. Gastroenterology. 2019 Jul;157(1):128-136.e5. doi: 10.1053/j.gastro.2019.03.015. Epub 2019 Mar 11. PMID: 30872105; PMCID: PMC6726378. |
| Dellon ES, Woosley JT, Arrington A, McGee SJ, Covington J, Moist SE, Gebhart JH, Tylicki AE, Shoyoye SO, Martin CF, Galanko JA, Baron JA, Shaheen NJ. Efficacy of Budesonide vs Fluticasone for Initial Treatment of Eosinophilic Esophagitis in a Randomized Controlled Trial. Gastroenterology. 2019 Jul;157(1):65-73.e5. doi: 10.1053/j.gastro.2019.03.014. Epub 2019 Mar 11. PMID: 30872104; PMCID: PMC6581596. |
| Lengfelder I, Sava IG, Hansen JJ, Kleigrewe K, Herzog J, Neuhaus K, Hofmann T, Sartor RB, Haller D. Complex Bacterial Consortia Reprogram the Colitogenic Activity of Enterococcus faecalis in a Gnotobiotic Mouse Model of Chronic, Immune-Mediated Colitis. Front Immunol. 2019 Jun 20;10:1420. doi: 10.3389/fimmu.2019.01420. PMID: 31281321; PMCID: PMC6596359. |
| Kakoki M, Bahnson EM, Hagaman JR, Siletzky RM, Grant R, Kayashima Y, Li F, Lee EY, Sun MT, Taylor JM, Rice JC, Almeida MF, Bahr BA, Jennette JC, Smithies O, Maeda-Smithies N. Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production. JCI Insight. 2019 Jun 20;4(12):e127660. doi: 10.1172/jci.insight.127660. PMID: 31217360; PMCID: PMC6629098. |
| Mishima Y, Oka A, Liu B, Herzog JW, Eun CS, Fan TJ, Bulik-Sullivan E, Carroll IM, Hansen JJ, Chen L, Wilson JE, Fisher NC, Ting JP, Nochi T, Wahl A, Garcia JV, Karp CL, Sartor RB. Microbiota maintain colonic homeostasis by activating TLR2/MyD88/PI3K signaling in IL-10-producing regulatory B cells. J Clin Invest. 2019 Jun 18;129(9):3702-3716. doi: 10.1172/JCI93820. PMID: 31211700; PMCID: PMC6715367. |
| Barnes EL, Long MD, Kappelman MD, Martin CF, Sandler RS. High Patient Activation Is Associated With Remission in Patients With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Jun 18;25(7):1248-1254. doi: 10.1093/ibd/izy378. PMID: 30590700; PMCID: PMC6939681. |
| Rothenberg SE, Wagner CL, Hamidi B, Alekseyenko AV, Andrea Azcarate-Peril M. Longitudinal changes during pregnancy in gut microbiota and methylmercury biomarkers, and reversal of microbe-exposure correlations. Environ Res. 2019 May;172:700-712. doi: 10.1016/j.envres.2019.01.014. Epub 2019 Jan 11. PMID: 30903970; PMCID: PMC6675619. |
| Furey TS, Sethupathy P, Sheikh SZ. Redefining the IBDs using genome-scale molecular phenotyping. Nat Rev Gastroenterol Hepatol. 2019 May;16(5):296-311. doi: 10.1038/s41575-019-0118-x. PMID: 30787446; PMCID: PMC8311467. |
| Eluri S, Selitsky SR, Perjar I, Hollyfield J, Betancourt R, Randall C, Rusin S, Woosley JT, Shaheen NJ, Dellon ES. Clinical and Molecular Factors Associated With Histologic Response to Topical Steroid Treatment in Patients With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2019 May;17(6):1081-1088.e2. doi: 10.1016/j.cgh.2018.09.005. Epub 2018 Sep 10. PMID: 30213583; PMCID: PMC6409124. |
| Schmitz JM, Tonkonogy SL, Dogan B, Leblond A, Whitehead KJ, Kim SC, Simpson KW, Sartor RB. Murine Adherent and Invasive E. coli Induces Chronic Inflammation and Immune Responses in the Small and Large Intestines of Monoassociated IL-10-/- Mice Independent of Long Polar Fimbriae Adhesin A. Inflamm Bowel Dis. 2019 Apr 11;25(5):875-885. doi: 10.1093/ibd/izy386. PMID: 30576451; PMCID: PMC6458545. |
| Jain A, Nguyen NH, Proudfoot JA, Martin CF, Sandborn WJ, Kappelman MD, Long MD, Singh S. Impact of Obesity on Disease Activity and Patient-Reported Outcomes Measurement Information System (PROMIS) in Inflammatory Bowel Diseases. Am J Gastroenterol. 2019 Apr;114(4):630-639. doi: 10.14309/ajg.0000000000000197. PMID: 30865012; PMCID: PMC6824268. |
| Barnes EL, Kappelman MD, Long MD, Evon DM, Martin CF, Sandler RS. A Novel Patient-Reported Outcome-Based Evaluation (PROBE) of Quality of Life in Patients With Inflammatory Bowel Disease. Am J Gastroenterol. 2019 Apr;114(4):640-647. doi: 10.14309/ajg.0000000000000177. PMID: 30848727; PMCID: PMC6450720. |
| Gonzalez LM, Stewart AS, Freund J, Kucera CR, Dekaney CM, Magness ST, Blikslager AT. Preservation of reserve intestinal epithelial stem cells following severe ischemic injury. Am J Physiol Gastrointest Liver Physiol. 2019 Apr 1;316(4):G482-G494. doi: 10.1152/ajpgi.00262.2018. Epub 2019 Feb 4. PMID: 30714814; PMCID: PMC6483022. |
| Weaver KN, Long MD. Preventive Medicine in Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2019 Apr;17(5):824-828. doi: 10.1016/j.cgh.2018.11.054. Epub 2018 Dec 6. PMID: 30529728. |
| Guadamuro L, Azcárate-Peril MA, Tojo R, Mayo B, Delgado S. Use of high throughput amplicon sequencing and ethidium monoazide dye to track microbiota changes in an equol-producing menopausal woman receiving a long-term isoflavones treatment. AIMS Microbiol. 2019 Mar 22;5(1):102-116. doi: 10.3934/microbiol.2019.1.102. PMID: 31384706; PMCID: PMC6646930. |
| Egberg MD, Galanko JA, Barnes EL, Kappelman MD. Thrombotic and Infectious Risks of Parenteral Nutrition in Hospitalized Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Feb 21;25(3):601-609. doi: 10.1093/ibd/izy298. PMID: 30304444; PMCID: PMC6383858. |
| Marler JD, Fujii CA, Utley DS, Tesfamariam LJ, Galanko JA, Patrick H. Initial Assessment of a Comprehensive Digital Smoking Cessation Program That Incorporates a Mobile App, Breath Sensor, and Coaching: Cohort Study. JMIR Mhealth Uhealth. 2019 Feb 4;7(2):e12609. doi: 10.2196/12609. PMID: 30670372; PMCID: PMC6378548. |
| Divaris K, Shungin D, Rodríguez-Cortés A, Basta PV, Roach J, Cho H, Wu D, Ferreira Zandoná AG, Ginnis J, Ramamoorthy S, Kinchen JM, Kwintkiewicz J, Butz N, Ribeiro AA, Azcarate-Peril MA. The Supragingival Biofilm in Early Childhood Caries: Clinical and Laboratory Protocols and Bioinformatics Pipelines Supporting Metagenomics, Metatranscriptomics, and Metabolomics Studies of the Oral Microbiome. Methods Mol Biol. 2019;1922:525-548. doi: 10.1007/978-1-4939-9012-2_40. PMID: 30838598; PMCID: PMC6628198. |
| Yeh A, Conners EM, Ramos-Jimenez RG, Firek B, Novak EA, Rogers MB, Cheek R, Ozolek J, Mollen KP, Morowitz MJ. Plant-based Enteral Nutrition Modifies the Gut Microbiota and Improves Outcomes in Murine Models of Colitis. Cell Mol Gastroenterol Hepatol. 2019;7(4):872-874.e6. doi: 10.1016/j.jcmgh.2019.01.007. Epub 2019 Feb 1. PMID: 30716421; PMCID: PMC6522637. |
| Zwarycz B, Gracz AD, Rivera KR, Williamson IA, Samsa LA, Starmer J, Daniele MA, Salter-Cid L, Zhao Q, Magness ST. IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model. Cell Mol Gastroenterol Hepatol. 2018 Jul 4;7(1):1-17. doi: 10.1016/j.jcmgh.2018.06.008. PMID: 30364840; PMCID: PMC6199238. |
| Eskildsen SM, Berkoff DJ, Kallianos SA, Weinhold PS. The use of an IL1-receptor antagonist to reverse the changes associated with established tendinopathy in a rat model. Scand J Med Sci Sports. 2019 Jan;29(1):82-88. doi: 10.1111/sms.13310. Epub 2018 Oct 15. PMID: 30256459; PMCID: PMC6289890. |
| Schoenborn AA, von Furstenberg RJ, Valsaraj S, Hussain FS, Stein M, Shanahan MT, Henning SJ, Gulati AS. The enteric microbiota regulates jejunal Paneth cell number and function without impacting intestinal stem cells. Gut Microbes. 2019;10(1):45-58. doi: 10.1080/19490976.2018.1474321. Epub 2018 Jul 11. PMID: 29883265; PMCID: PMC6363071. |
| Ananthakrishnan AN, Martin C, Kane S, Sandler RS, Long MD. Paternal Disease Activity Is Associated With Difficulty in Conception Among Men With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2019 Jan;17(1):203-204. doi: 10.1016/j.cgh.2018.04.001. Epub 2018 Apr 11. PMID: 29653290; PMCID: PMC6181789. |
| Sandler RS, Peery AF. Rethinking What We Know About Hemorrhoids. Clin Gastroenterol Hepatol. 2019 Jan;17(1):8-15. doi: 10.1016/j.cgh.2018.03.020. Epub 2018 Mar 27. PMID: 29601902; PMCID: PMC7075634. |
| Runge WO, Ruppert DS, Marcellin-Little DJ, Dahners LE, Harrysson O, Weinhold PS. Bone changes after short-term whole body vibration are confined to cancellous bone. J Musculoskelet Neuronal Interact. 2018 Dec 1;18(4):485-492. PMID: 30511952; PMCID: PMC6313037. |
| Jin Y, Ibrahim D, Magness ST, Blikslager AT. Knockout of ClC-2 reveals critical functions of adherens junctions in colonic homeostasis and tumorigenicity. Am J Physiol Gastrointest Liver Physiol. 2018 Dec 1;315(6):G966-G979. doi: 10.1152/ajpgi.00087.2018. Epub 2018 Oct 4. PMID: 30285466; PMCID: PMC6336945. |
| Egberg MD, Mitchell PD, Galanko JA, Rufo PA. Effectiveness of oral iron supplementation in treatment of anemia associated with pediatric ulcerative colitis flare. Am J Hematol. 2018 Dec;93(12):E404-E406. doi: 10.1002/ajh.25299. Epub 2018 Oct 23. PMID: 30264865; PMCID: PMC6260819. |
| Gracz AD, Samsa LA, Fordham MJ, Trotier DC, Zwarycz B, Lo YH, Bao K, Starmer J, Raab JR, Shroyer NF, Reinhardt RL, Magness ST. Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates. Gastroenterology. 2018 Nov;155(5):1508-1523.e10. doi: 10.1053/j.gastro.2018.07.023. Epub 2018 Jul 25. PMID: 30055169; PMCID: PMC6232678. |
| Efird WM, Fletcher AG, Draeger RW, Spang JT, Dahners LE, Weinhold PS. Deferoxamine-Soaked Suture Improves Angiogenesis and Repair Potential After Acute Injury of the Chicken Achilles Tendon. Orthop J Sports Med. 2018 Oct 23;6(10):2325967118802792. doi: 10.1177/2325967118802792. PMID: 30370309; PMCID: PMC6201186. |
| Fan TJ, Tchaptchet SY, Arsene D, Mishima Y, Liu B, Sartor RB, Carroll IM, Miao EA, Fodor AA, Hansen JJ. Environmental Factors Modify the Severity of Acute DSS Colitis in Caspase-11-Deficient Mice. Inflamm Bowel Dis. 2018 Oct 12;24(11):2394-2403. doi: 10.1093/ibd/izy244. PMID: 30312415; PMCID: PMC6185382. |
| Ho NT, Li F, Lee-Sarwar KA, Tun HM, Brown BP, Pannaraj PS, Bender JM, Azad MB, Thompson AL, Weiss ST, Azcarate-Peril MA, Litonjua AA, Kozyrskyj AL, Jaspan HB, Aldrovandi GM, Kuhn L. Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations. Nat Commun. 2018 Oct 9;9(1):4169. doi: 10.1038/s41467-018-06473-x. PMID: 30301893; PMCID: PMC6177445. |
| Eaton K, Pirani A, Snitkin ES; Reproducibility Project: Cancer Biology. Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota. Elife. 2018 Oct 8;7:e34364. doi: 10.7554/eLife.34364. PMID: 30295289; PMCID: PMC6175580. |
| Keith BP, Barrow JB, Toyonaga T, Kazgan N, O'Connor MH, Shah ND, Schaner MS, Wolber EA, Trad OK, Gipson GR, Pitman WA, Kanke M, Saxena SJ, Chaumont N, Sadiq TS, Koruda MJ, Cotney PA, Allbritton N, Trembath DG, Sylvester F, Furey TS, Sethupathy P, Sheikh SZ. Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. JCI Insight. 2018 Oct 4;3(19):e122788. doi: 10.1172/jci.insight.122788. PMID: 30282822; PMCID: PMC6237459. |
| Chung AE, Vu MB, Myers K, Burris J, Kappelman MD. Crohn's and Colitis Foundation of America Partners Patient-Powered Research Network: Patient Perspectives on Facilitators and Barriers to Building an Impactful Patient- Powered Research Network. Med Care. 2018 Oct;56 Suppl 10 Suppl 1(10 Suppl 1):S33-S40. doi: 10.1097/MLR.0000000000000771. PMID: 30074949; PMCID: PMC6143211. |
| Herfarth H, Barnes EL, Valentine JF, Hanson J, Higgins PDR, Isaacs KL, Jackson S, Osterman MT, Anton K, Ivanova A, Long MD, Martin C, Sandler RS, Abraham B, Cross RK, Dryden G, Fischer M, Harlan W, Levy C, McCabe R, Polyak S, Saha S, Williams E, Yajnik V, Serrano J, Sands BE, Lewis JD; Clinical Research Alliance of the Crohn’s and Colitis Foundation. Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis. Gastroenterology. 2018 Oct;155(4):1098-1108.e9. doi: 10.1053/j.gastro.2018.06.046. Epub 2018 Jun 30. PMID: 29964043; PMCID: PMC6174092. |
| Tappata M, Eluri S, Perjar I, Hollyfield J, Betancourt R, Randall C, Woosley JT, Wechsler JB, Dellon ES. Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy. 2018 Oct;73(10):2088-2092. doi: 10.1111/all.13530. Epub 2018 Jul 13. PMID: 29935026; PMCID: PMC6207454. |
| Kaelberer MM, Buchanan KL, Klein ME, Barth BB, Montoya MM, Shen X, Bohórquez DV. A gut-brain neural circuit for nutrient sensory transduction. Science. 2018 Sep 21;361(6408):eaat5236. doi: 10.1126/science.aat5236. PMID: 30237325; PMCID: PMC6417812. |
| Truax AD, Chen L, Tam JW, Cheng N, Guo H, Koblansky AA, Chou WC, Wilson JE, Brickey WJ, Petrucelli A, Liu R, Cooper DE, Koenigsknecht MJ, Young VB, Netea MG, Stienstra R, Sartor RB, Montgomery SA, Coleman RA, Ting JP. The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis. Cell Host Microbe. 2018 Sep 12;24(3):364-378.e6. doi: 10.1016/j.chom.2018.08.009. PMID: 30212649; PMCID: PMC6161752. |
| Mackie DI, Al Mutairi F, Davis RB, Kechele DO, Nielsen NR, Snyder JC, Caron MG, Kliman HJ, Berg JS, Simms J, Poyner DR, Caron KM. hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. J Exp Med. 2018 Sep 3;215(9):2339-2353. doi: 10.1084/jem.20180528. Epub 2018 Aug 16. PMID: 30115739; PMCID: PMC6122977. |
| Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, Devkota S, Braun J, Michelsen KS, Targan SR, Shih DQ. Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunol. 2018 Sep;11(5):1466-1476. doi: 10.1038/s41385-018-0055-y. Epub 2018 Jul 9. PMID: 29988118; PMCID: PMC6162160. |
| Ziegler AL, Pridgen TA, Mills JK, Gonzalez LM, Van Landeghem L, Odle J, Blikslager AT. Epithelial restitution defect in neonatal jejunum is rescued by juvenile mucosal homogenate in a pig model of intestinal ischemic injury and repair. PLoS One. 2018 Aug 23;13(8):e0200674. doi: 10.1371/journal.pone.0200674. Erratum in: PLoS One. 2019 Feb 22;14(2):e0212962. PMID: 30138372; PMCID: PMC6107120. |
| Valès S, Touvron M, Van Landeghem L. Enteric glia: Diversity or plasticity? Brain Res. 2018 Aug 15;1693(Pt B):140-145. doi: 10.1016/j.brainres.2018.02.001. Epub 2018 Feb 7. PMID: 29425908. |
| Palacios M, Miner TA, Frederick DR, Sepulveda VE, Quinn JD, Walker KA, Miller VL. Identification of Two Regulators of Virulence That Are Conserved in Klebsiella pneumoniae Classical and Hypervirulent Strains. mBio. 2018 Aug 7;9(4):e01443-18. doi: 10.1128/mBio.01443-18. PMID: 30087173; PMCID: PMC6083908. |
| Evon DM, Stewart PW, Amador J, Serper M, Lok AS, Sterling RK, Sarkar S, Golin CE, Reeve BB, Nelson DR, Reau N, Lim JK, Reddy KR, Di Bisceglie AM, Fried MW. A comprehensive assessment of patient reported symptom burden, medical comorbidities, and functional well being in patients initiating direct acting antiviral therapy for chronic hepatitis C: Results from a large US multi-center observational study. PLoS One. 2018 Aug 1;13(8):e0196908. doi: 10.1371/journal.pone.0196908. PMID: 30067745; PMCID: PMC6070182. |
| Ulici V, Kelley KL, Azcarate-Peril MA, Cleveland RJ, Sartor RB, Schwartz TA, Loeser RF. Osteoarthritis induced by destabilization of the medial meniscus is reduced in germ-free mice. Osteoarthritis Cartilage. 2018 Aug;26(8):1098-1109. doi: 10.1016/j.joca.2018.05.016. Epub 2018 May 30. PMID: 29857156; PMCID: PMC7970023. |
| Dellon ES, Selitsky SR, Genta RM, Lash RH, Parker JS. Gene expression- phenotype associations in adults with eosinophilic esophagitis. Dig Liver Dis. 2018 Aug;50(8):804-811. doi: 10.1016/j.dld.2018.03.021. Epub 2018 Mar 27. PMID: 29628359; PMCID: PMC6059985. |
| Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018 Jul 16;9(1):2745. doi: 10.1038/s41467-018-04974-3. PMID: 30013031; PMCID: PMC6048100. |
| Pollard KL, Campbell C, Squires M, Palsson O, van Tilburg MAL. Seasonal Association of Pediatric Functional Abdominal Pain Disorders and Anxiety. J Pediatr Gastroenterol Nutr. 2018 Jul;67(1):18-22. doi: 10.1097/MPG.0000000000001886. PMID: 29287016; PMCID: PMC6013328. |
| Evon DM, Golin CE, Ruffin R, Ayres S, Fried MW. Novel patient-reported outcomes (PROs) used in a pilot and feasibility study of a Cognitive Behavioral Coping Skills (CBCS) group intervention for patients with chronic hepatitis C. Pilot Feasibility Stud. 2018 Jun 27;4:92. doi: 10.1186/s40814-018-0285-5. PMID: 29983993; PMCID: PMC6020443. |
| Busch EL, Galanko JA, Sandler RS, Goel A, Keku TO. Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans. Sci Rep. 2018 Jun 21;8(1):9470. doi: 10.1038/s41598-018-27738-x. PMID: 29930328; PMCID: PMC6013500. |
| Reese AT, Cho EH, Klitzman B, Nichols SP, Wisniewski NA, Villa MM, Durand HK, Jiang S, Midani FS, Nimmagadda SN, O'Connell TM, Wright JP, Deshusses MA, David LA. Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. Elife. 2018 Jun 19;7:e35987. doi: 10.7554/eLife.35987. PMID: 29916366; PMCID: PMC6008055. |
| Lee MK, Carnes MU, Butz N, Azcarate-Peril MA, Richards M, Umbach DM, Thorne PS, Beane Freeman LE, Peddada SD, London SJ. Exposures Related to House Dust Microbiota in a U.S. Farming Population. Environ Health Perspect. 2018 Jun 1;126(6):067001. doi: 10.1289/EHP3145. PMID: 29863827; PMCID: PMC6084882. |
| Kerlin AM, Long M, Kappelman M, Martin C, Sandler RS. Profiles of Patients Who Use Marijuana for Inflammatory Bowel Disease. Dig Dis Sci. 2018 Jun;63(6):1600-1604. doi: 10.1007/s10620-018-5040-5. Epub 2018 Mar 29. PMID: 29594968. |
| Eluri S, Cross RK, Martin C, Weinfurt KP, Flynn KE, Long MD, Chen W, Anton K, Sandler RS, Kappelman MD. Inflammatory Bowel Diseases Can Adversely Impact Domains of Sexual Function Such as Satisfaction with Sex Life. Dig Dis Sci. 2018 Jun;63(6):1572-1582. doi: 10.1007/s10620-018-5021-8. Epub 2018 Mar 21. Erratum in: Dig Dis Sci. 2018 Oct;63(10):2816. PMID: 29564672; PMCID: PMC5955825. |
| Peery AF, Keku TO, Addamo C, McCoy AN, Martin CF, Galanko JA, Sandler RS. Colonic Diverticula Are Not Associated With Mucosal Inflammation or Chronic Gastrointestinal Symptoms. Clin Gastroenterol Hepatol. 2018 Jun;16(6):884-891.e1. doi: 10.1016/j.cgh.2017.05.051. Epub 2017 Jun 8. PMID: 28603053; PMCID: PMC5722710. |
| Williamson IA, Arnold JW, Samsa LA, Gaynor L, DiSalvo M, Cocchiaro JL, Carroll I, Azcarate-Peril MA, Rawls JF, Allbritton NL, Magness ST. A High- Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology. Cell Mol Gastroenterol Hepatol. 2018 May 22;6(3):301-319. doi: 10.1016/j.jcmgh.2018.05.004. PMID: 30123820; PMCID: PMC6092482. |
| Stieler Stewart A, Freund JM, Blikslager AT, Gonzalez LM. Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia. J Vis Exp. 2018 May 18;(135):57647. doi: 10.3791/57647. PMID: 29863654; PMCID: PMC6101266. |
| Li F, Kakoki M, Smid M, Boggess K, Wilder J, Hiller S, Bounajim C, Parnell SE, Sulik KK, Smithies O, Maeda-Smithies N. Causative Effects of Genetically Determined High Maternal/Fetal Endothelin-1 on Preeclampsia-Like Conditions in Mice. Hypertension. 2018 May;71(5):894-903. doi: 10.1161/HYPERTENSIONAHA.117.10849. Epub 2018 Apr 2. PMID: 29610266; PMCID: PMC5897184. |
| Pushalkar S, Hundeyin M, Daley D, Zambirinis CP, Kurz E, Mishra A, Mohan N, Aykut B, Usyk M, Torres LE, Werba G, Zhang K, Guo Y, Li Q, Akkad N, Lall S, Wadowski B, Gutierrez J, Kochen Rossi JA, Herzog JW, Diskin B, Torres-Hernandez A, Leinwand J, Wang W, Taunk PS, Savadkar S, Janal M, Saxena A, Li X, Cohen D, Sartor RB, Saxena D, Miller G. The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression. Cancer Discov. 2018 Apr;8(4):403-416. doi: 10.1158/2159-8290.CD-17-1134. Epub 2018 Mar 22. Erratum in: Cancer Discov. 2020 Dec;10(12):1988. PMID: 29567829; PMCID: PMC6225783. |
| Evon DM, Amador J, Stewart P, Reeve BB, Lok AS, Sterling RK, Di Bisceglie AM, Reau N, Serper M, Sarkar S, Lim JK, Golin CE, Fried MW. Psychometric properties of the PROMIS short form measures in a U.S. cohort of 961 patients with chronic hepatitis C prescribed direct acting antiviral therapy. Aliment Pharmacol Ther. 2018 Apr;47(7):1001-1011. doi: 10.1111/apt.14531. Epub 2018 Jan 29. PMID: 29377191; PMCID: PMC5842131. |
| Dong J, Buas MF, Gharahkhani P, Kendall BJ, Onstad L, Zhao S, Anderson LA, Wu AH, Ye W, Bird NC, Bernstein L, Chow WH, Gammon MD, Liu G, Caldas C, Pharoah PD, Risch HA, Iyer PG, Reid BJ, Hardie LJ, Lagergren J, Shaheen NJ, Corley DA, Fitzgerald RC; Stomach and Oesophageal Cancer Study (SOCS) consortium, Whiteman DC, Vaughan TL, Thrift AP. Determining Risk of Barrett's Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants. Gastroenterology. 2018 Apr;154(5):1273-1281.e3. doi: 10.1053/j.gastro.2017.12.003. Epub 2017 Dec 13. PMID: 29247777; PMCID: PMC5880715. |
| Jones RB, Fodor AA, Peery AF, Tsilimigras MCB, Winglee K, McCoy A, Sioda M, Sandler RS, Keku TO. An Aberrant Microbiota is not Strongly Associated with Incidental Colonic Diverticulosis. Sci Rep. 2018 Mar 21;8(1):4951. doi: 10.1038/s41598-018-23023-z. PMID: 29563543; PMCID: PMC5862835. |
| Smith NR, Swain JR, Davies PS, Gallagher AC, Parappilly MS, Beach CZ, Streeter PR, Williamson IA, Magness ST, Wong MH. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol. 2018 Mar 10;6(1):79-96. doi: 10.1016/j.jcmgh.2018.02.007. PMID: 29928673; PMCID: PMC6008251. |
| Kochar B, Barnes EL, Herfarth HH, Martin CF, Ananthakrishnan AN, McGovern D, Long M, Sandler RS. Asians have more perianal Crohn disease and ocular manifestations compared with white Americans. Inflamm Intest Dis. 2018 Mar;2(3):147-153. doi: 10.1159/000484347. Epub 2017 Nov 18. PMID: 29876356; PMCID: PMC5986188. |
| Azcarate-Peril MA, Butz N, Cadenas MB, Koci M, Ballou A, Mendoza M, Ali R, Hassan H. An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome. Appl Environ Microbiol. 2018 Feb 14;84(5):e02526-17. doi: 10.1128/AEM.02526-17. PMID: 29269490; PMCID: PMC5812947. |
| Walker MY, Pratap S, Southerland JH, Farmer-Dixon CM, Lakshmyya K, Gangula PR. Role of oral and gut microbiome in nitric oxide-mediated colon motility. Nitric Oxide. 2018 Feb 28;73:81-88. doi: 10.1016/j.niox.2017.06.003. Epub 2017 Jun 7. PMID: 28602746; PMCID: PMC6104390. |
| Zhang Q, Ke H, Blikslager A, Fujita T, Yoo D. Type III Interferon Restriction by Porcine Epidemic Diarrhea Virus and the Role of Viral Protein nsp1 in IRF1 Signaling. J Virol. 2018 Jan 30;92(4):e01677-17. doi: 10.1128/JVI.01677-17. PMID: 29187542; PMCID: PMC5790939. |
| Blikslager A, Gonzalez L. Equine Intestinal Mucosal Pathobiology. Annu Rev Anim Biosci. 2018 Feb 15;6:157-175. doi: 10.1146/annurev-animal-030117-014748. Epub 2017 Nov 16. PMID: 29144770; PMCID: PMC7769316. |
| Rogala AR, Schoenborn AA, Fee BE, Cantillana VA, Joyce MJ, Gharaibeh RZ, Roy S, Fodor AA, Sartor RB, Taylor GA, Gulati AS. Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice. Dis Model Mech. 2018 Feb 7;11(2):dmm031070. doi: 10.1242/dmm.031070. PMID: 29361512; PMCID: PMC5894938. |
| Schulfer AF, Battaglia T, Alvarez Y, Bijnens L, Ruiz VE, Ho M, Robinson S, Ward T, Cox LM, Rogers AB, Knights D, Sartor RB, Blaser MJ. Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice. Nat Microbiol. 2018 Feb;3(2):234-242. doi: 10.1038/s41564-017-0075-5. Epub 2017 Nov 27. PMID: 29180726; PMCID: PMC5780248. |
| Reed CC, Wolf WA, Cotton CC, Rusin S, Perjar I, Hollyfield J, Woosley JT, Shaheen NJ, Dellon ES. Optimal Histologic Cutpoints for Treatment Response in Patients With Eosinophilic Esophagitis: Analysis of Data From a Prospective Cohort Study. Clin Gastroenterol Hepatol. 2018 Feb;16(2):226-233.e2. doi: 10.1016/j.cgh.2017.09.046. Epub 2017 Oct 4. PMID: 28987502; PMCID: PMC6582220. |
| Vyas D, Baptista PM, Brovold M, Moran E, Gaston B, Booth C, Samuel M, Atala A, Soker S. Self-assembled liver organoids recapitulate hepatobiliary organogenesis in vitro. Hepatology. 2018 Feb;67(2):750-761. doi: 10.1002/hep.29483. Epub 2018 Jan 2. PMID: 28834615; PMCID: PMC5825235. |
| Rolston VS, Boroujerdi L, Long MD, McGovern DPB, Chen W, Martin CF, Sandler RS, Carmichael JD, Dubinsky M, Melmed GY. The Influence of Hormonal Fluctuation on Inflammatory Bowel Disease Symptom Severity-A Cross-Sectional Cohort Study. Inflamm Bowel Dis. 2018 Jan 18;24(2):387-393. doi: 10.1093/ibd/izx004. PMID: 29361085; PMCID: PMC6196767. |
| Busch EL, Don PK, Chu H, Richardson DB, Keku TO, Eberhard DA, Avery CL, Sandler RS. Diagnostic accuracy and prediction increment of markers of epithelial-mesenchymal transition to assess cancer cell detachment from primary tumors. BMC Cancer. 2018 Jan 16;18(1):82. doi: 10.1186/s12885-017-3964-3. PMID: 29338703; PMCID: PMC5769498. |
| Carlson AL, Xia K, Azcarate-Peril MA, Goldman BD, Ahn M, Styner MA, Thompson AL, Geng X, Gilmore JH, Knickmeyer RC. Infant Gut Microbiome Associated With Cognitive Development. Biol Psychiatry. 2018 Jan 15;83(2):148-159. doi: 10.1016/j.biopsych.2017.06.021. Epub 2017 Jun 27. PMID: 28793975; PMCID: PMC5724966. |
| Yan J, Takakura A, Zandi-Nejad K, Charles JF. Mechanisms of gut microbiota- mediated bone remodeling. Gut Microbes. 2018 Jan 2;9(1):84-92. doi: 10.1080/19490976.2017.1371893. Epub 2017 Sep 29. Erratum for: Addendum to: Yan J, Herzog JW, Tsang K, Brennan CA, Bower MA, Garrett WS, Sartor BR, Aliprantis AO, Charles JF. Gut microbiota induce IGF-1 and promote bone formation and growth. Proc Natl Acad Sci USA. 2016 11 22; 113(47):E7554-E7563. Epub 2016 Nov 7. PMID: 28961041; PMCID: PMC5914914. |
| Ellermann M, Sartor RB. Intestinal bacterial biofilms modulate mucosal immune responses. J Immunol Sci. 2018;2(2):13-18. PMID: 30393787; PMCID: PMC6214460. |
| Samsa LA, Williamson IA, Magness ST. Quantitative Analysis of Intestinal Stem Cell Dynamics Using Microfabricated Cell Culture Arrays. Methods Mol Biol. 2018;1842:139-166. doi: 10.1007/978-1-4939-8697-2_10. PMID: 30196407. |
| Zwarycz B, Gracz AD, Magness ST. Organoid Cultures for Assessing Intestinal Epithelial Differentiation and Function in Response to Type-2 Inflammation. Methods Mol Biol. 2018;1799:397-417. doi: 10.1007/978-1-4939-7896-0_29. PMID: 29956167. |
| Kochar B, Barnes EL, Long MD, Cushing KC, Galanko J, Martin CF, Raffals LE, Sandler RS. Depression Is Associated With More Aggressive Inflammatory Bowel Disease. Am J Gastroenterol. 2018 Jan;113(1):80-85. doi: 10.1038/ajg.2017.423. Epub 2017 Nov 14. PMID: 29134965; PMCID: PMC5962285. |
| Koutlas NT, Eluri S, Rusin S, Perjar I, Hollyfield J, Woosley JT, Shaheen NJ, Dellon ES. Impact of smoking, alcohol consumption, and NSAID use on risk for and phenotypes of eosinophilic esophagitis. Dis Esophagus. 2018 Jan 1;31(1):1-7. doi: 10.1093/dote/dox111. PMID: 29025076; PMCID: PMC6036648. |
| Kochar B, Martin CF, Kappelman MD, Spiegel BM, Chen W, Sandler RS, Long MD. Evaluation of Gastrointestinal Patient Reported Outcomes Measurement Information System (GI-PROMIS) Symptom Scales in Subjects With Inflammatory Bowel Diseases. Am J Gastroenterol. 2018 Jan;113(1):72-79. doi: 10.1038/ajg.2017.240. Epub 2017 Aug 29. PMID: 28853727. |
| Smid MC, Ricks NM, Panzer A, Mccoy AN, Azcarate-Peril MA, Keku TO, Boggess KA. Maternal Gut Microbiome Biodiversity in Pregnancy. Am J Perinatol. 2018 Jan;35(1):24-30. doi: 10.1055/s-0037-1604412. Epub 2017 Jul 27. PMID: 28750469; PMCID: PMC6102712. |
| Peery AF, Shaheen NJ, Cools KS, Baron TH, Koruda M, Galanko JA, Grimm IS. Morbidity and mortality after surgery for nonmalignant colorectal polyps. Gastrointest Endosc. 2018 Jan;87(1):243-250.e2. doi: 10.1016/j.gie.2017.03.1550. Epub 2017 Apr 10. PMID: 28408327; PMCID: PMC5634910. |
| Ho GT, Aird RE, Liu B, Boyapati RK, Kennedy NA, Dorward DA, Noble CL, Shimizu T, Carter RN, Chew ETS, Morton NM, Rossi AG, Sartor RB, Iredale JP, Satsangi J. MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation. Mucosal Immunol. 2018 Jan;11(1):120-130. doi: 10.1038/mi.2017.31. Epub 2017 Apr 12. PMID: 28401939; PMCID: PMC5510721. |
| Weiser M, Simon JM, Kochar B, Tovar A, Israel JW, Robinson A, Gipson GR, Schaner MS, Herfarth HH, Sartor RB, McGovern DPB, Rahbar R, Sadiq TS, Koruda MJ, Furey TS, Sheikh SZ. Molecular classification of Crohn's disease reveals two clinically relevant subtypes. Gut. 2018 Jan;67(1):36-42. doi: 10.1136/gutjnl-2016-312518. Epub 2016 Oct 14. PMID: 27742763; PMCID: PMC5426990. |
| Hirsch ML, Conatser LM, Smith SM, Salmon JH, Wu J, Buglak NE, Davis R, Gilger BC. AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis. Sci Rep. 2017 Dec 19;7(1):17840. doi: 10.1038/s41598-017-18002-9. PMID: 29259248; PMCID: PMC5736662. |
| Ziegler AL, Blikslager AT. Impaired intestinal barrier function and relapsing digestive disease: Lessons from a porcine model of early life stress. Neurogastroenterol Motil. 2017 Nov;29(11):1-4. doi: 10.1111/nmo.13216. PMID: 29052972; PMCID: PMC5940449. |
| von Furstenberg RJ, Li J, Stolarchuk C, Feder R, Campbell A, Kruger L, Gonzalez LM, Blikslager AT, Cardona DM, McCall SJ, Henning SJ, Garman KS. Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation. Cell Mol Gastroenterol Hepatol. 2017 Aug 4;4(3):385-404. doi: 10.1016/j.jcmgh.2017.07.005. PMID: 28936470; PMCID: PMC5602779. |
| Anderson JR, Carroll I, Azcarate-Peril MA, Rochette AD, Heinberg LJ, Peat C, Steffen K, Manderino LM, Mitchell J, Gunstad J. A preliminary examination of gut microbiota, sleep, and cognitive flexibility in healthy older adults. Sleep Med. 2017 Oct;38:104-107. doi: 10.1016/j.sleep.2017.07.018. Epub 2017 Aug 2. PMID: 29031742; PMCID: PMC7433257. |
| Lough KJ, Byrd KM, Spitzer DC, Williams SE. Closing the Gap: Mouse Models to Study Adhesion in Secondary Palatogenesis. J Dent Res. 2017 Oct;96(11):1210-1220. doi: 10.1177/0022034517726284. Epub 2017 Aug 17. PMID: 28817360; PMCID: PMC5613886. |
| Seidel DV, Azcárate-Peril MA, Chapkin RS, Turner ND. Shaping functional gut microbiota using dietary bioactives to reduce colon cancer risk. Semin Cancer Biol. 2017 Oct;46:191-204. doi: 10.1016/j.semcancer.2017.06.009. Epub 2017 Jul 1. PMID: 28676459; PMCID: PMC5626600. |
| Allali I, Arnold JW, Roach J, Cadenas MB, Butz N, Hassan HM, Koci M, Ballou A, Mendoza M, Ali R, Azcarate-Peril MA. A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome. BMC Microbiol. 2017 Sep 13;17(1):194. doi: 10.1186/s12866-017-1101-8. PMID: 28903732; PMCID: PMC5598039. |
| Manderino L, Carroll I, Azcarate-Peril MA, Rochette A, Heinberg L, Peat C, Steffen K, Mitchell J, Gunstad J. Preliminary Evidence for an Association Between the Composition of the Gut Microbiome and Cognitive Function in Neurologically Healthy Older Adults. J Int Neuropsychol Soc. 2017 Sep;23(8):700-705. doi: 10.1017/S1355617717000492. Epub 2017 Jun 23. PMID: 28641593; PMCID: PMC6111127. |
| Krüger L, Gonzalez LM, Pridgen TA, McCall SJ, von Furstenberg RJ, Harnden I, Carnighan GE, Cox AM, Blikslager AT, Garman KS. Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair. Am J Physiol Gastrointest Liver Physiol. 2017 Sep 1;313(3):G180-G191. doi: 10.1152/ajpgi.00036.2017. Epub 2017 Jun 1. PMID: 28572084; PMCID: PMC5625137. |
| Wellman AS, Metukuri MR, Kazgan N, Xu X, Xu Q, Ren NSX, Czopik A, Shanahan MT, Kang A, Chen W, Azcarate-Peril MA, Gulati AS, Fargo DC, Guarente L, Li X. Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota. Gastroenterology. 2017 Sep;153(3):772-786. doi: 10.1053/j.gastro.2017.05.022. Epub 2017 May 26. PMID: 28552621; PMCID: PMC5581719. |
| Azzam KM, Madenspacher JH, Cain DW, Lai L, Gowdy KM, Rai P, Janardhan K, Clayton N, Cunningham W, Jensen H, Patel PS, Kearney JF, Taylor GA, Fessler MB. Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces. JCI Insight. 2017 Aug 17;2(16):e91914. doi: 10.1172/jci.insight.91914. PMID: 28814662; PMCID: PMC5621910. |
| Tubbs AL, Liu B, Rogers TD, Sartor RB, Miao EA. Dietary Salt Exacerbates Experimental Colitis. J Immunol. 2017 Aug 1;199(3):1051-1059. doi: 10.4049/jimmunol.1700356. Epub 2017 Jun 21. PMID: 28637899; PMCID: PMC5576735. |
| Fedirko V, McKeown-Eyssen G, Serhan CN, Barry EL, Sandler RS, Figueiredo JC, Ahnen DJ, Bresalier RS, Robertson DJ, Anderson CW, Baron JA. Plasma lipoxin A4 and resolvin D1 are not associated with reduced adenoma risk in a randomized trial of aspirin to prevent colon adenomas. Mol Carcinog. 2017 Aug;56(8):1977-1983. doi: 10.1002/mc.22629. Epub 2017 Mar 6. PMID: 28218420; PMCID: PMC5496792. |
| Bartelt LA, Bolick DT, Mayneris-Perxachs J, Kolling GL, Medlock GL, Zaenker EI, Donowitz J, Thomas-Beckett RV, Rogala A, Carroll IM, Singer SM, Papin J, Swann JR, Guerrant RL. Cross-modulation of pathogen-specific pathways enhances malnutrition during enteric co-infection with Giardia lamblia and enteroaggregative Escherichia coli. PLoS Pathog. 2017 Jul 27;13(7):e1006471. doi: 10.1371/journal.ppat.1006471. PMID: 28750066; PMCID: PMC5549954. |
| Ribeiro AA, Azcarate-Peril MA, Cadenas MB, Butz N, Paster BJ, Chen T, Bair E, Arnold RR. The oral bacterial microbiome of occlusal surfaces in children and its association with diet and caries. PLoS One. 2017 Jul 5;12(7):e0180621. doi: 10.1371/journal.pone.0180621. PMID: 28678838; PMCID: PMC5498058. |
| Ananthakrishnan AN, Sakuraba A, Barnes EL, Pekow J, Raffals L, Long MD, Sandler RS. The benefit of combination therapy depends on disease phenotype and duration in Crohn's disease. Aliment Pharmacol Ther. 2017 Jul;46(2):162-168. doi: 10.1111/apt.14125. Epub 2017 May 3. PMID: 28470787; PMCID: PMC5484085. |
| Barnes EL, Herfarth HH, Sandler RS, Chen W, Jaeger E, Nguyen VM, Robb AR, Kappelman MD, Martin CF, Long MD. Pouch-Related Symptoms and Quality of Life in Patients with Ileal Pouch-Anal Anastomosis. Inflamm Bowel Dis. 2017 Jul;23(7):1218-1224. doi: 10.1097/MIB.0000000000001119. PMID: 28426474; PMCID: PMC5512700. |
| Kochar B, Long MD, Galanko J, Raffals LE, Ananthakrishnan A, Sandler RS. Inflammatory Bowel Disease is Similar in Patients with Older Onset and Younger Onset. Inflamm Bowel Dis. 2017 Jul;23(7):1187-1194. doi: 10.1097/MIB.0000000000001115. PMID: 28410340; PMCID: PMC5469700. |
| Davison JM, Lickwar CR, Song L, Breton G, Crawford GE, Rawls JF. Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha. Genome Res. 2017 Jul;27(7):1195-1206. doi: 10.1101/gr.220111.116. Epub 2017 Apr 6. PMID: 28385711; PMCID: PMC5495071. |
| Kochar B, Long MD, Shelton E, Young L, Farraye FA, Yajnik V, Herfarth H. Safety and Efficacy of Teduglutide (Gattex) in Patients With Crohn's Disease and Need for Parenteral Support Due to Short Bowel Syndrome-associated Intestinal Failure. J Clin Gastroenterol. 2017 Jul;51(6):508-511. doi: 10.1097/MCG.0000000000000604. PMID: 27433811; PMCID: PMC5243925. |
| Johnson BR, O'Flaherty S, Goh YJ, Carroll I, Barrangou R, Klaenhammer TR. The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface- Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM. Front Microbiol. 2017 Jun 30;8:1185. doi: 10.3389/fmicb.2017.01185. PMID: 28713337; PMCID: PMC5491966. |
| Tech K, Tikunov AP, Farooq H, Morrissy AS, Meidinger J, Fish T, Green SC, Liu H, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJM, Marra MA, Vander Heiden MG, Taylor MD, Macdonald JM, Gershon TR. Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation. Cancer Res. 2017 Jun 15;77(12):3217-3230. doi: 10.1158/0008-5472.CAN-16-3304. Epub 2017 May 17. PMID: 28515149; PMCID: PMC5497486. |
| Ziegler A, Fogle C, Blikslager A. Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses. J Am Vet Med Assoc. 2017 Jun 1;250(11):1271-1274. doi: 10.2460/javma.250.11.1271. PMID: 28509650; PMCID: PMC5588883. |
| Barnes EL, Kochar B, Long MD, Kappelman MD, Martin CF, Korzenik JR, Crockett SD. Modifiable Risk Factors for Hospital Readmission Among Patients with Inflammatory Bowel Disease in a Nationwide Database. Inflamm Bowel Dis. 2017 Jun;23(6):875-881. doi: 10.1097/MIB.0000000000001121. PMID: 28426473; PMCID: PMC5512697. |
| Reed CC, Wolf WA, Cotton CC, Dellon ES. A visual analogue scale and a Likert scale are simple and responsive tools for assessing dysphagia in eosinophilic oesophagitis. Aliment Pharmacol Ther. 2017 Jun;45(11):1443-1448. doi: 10.1111/apt.14061. Epub 2017 Mar 31. PMID: 28370355; PMCID: PMC5419874. |
| Minchin JEN, Rawls JF. A classification system for zebrafish adipose tissues. Dis Model Mech. 2017 Jun 1;10(6):797-809. doi: 10.1242/dmm.025759. Epub 2017 Mar 27. PMID: 28348140; PMCID: PMC5482999. |
| Evon DM, Golin CE, Stoica T, Jones RE, Willis SJ, Galanko J, Fried MW. What's Important to the Patient? Informational Needs of Patients Making Decisions About Hepatitis C Treatment. Patient. 2017 Jun;10(3):335-344. doi: 10.1007/s40271-016-0207-7. PMID: 27882509; PMCID: PMC5597439. |
| Soto R, Petersen C, Novis CL, Kubinak JL, Bell R, Stephens WZ, Lane TE, Fujinami RS, Bosque A, O'Connell RM, Round JL. Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5497-5502. doi: 10.1073/pnas.1619336114. Epub 2017 May 9. PMID: 28487480; PMCID: PMC5448176. |
| Battaglia RA, Kabiraj P, Willcockson HH, Lian M, Snider NT. Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging- associated Post-translational Modifications. J Vis Exp. 2017 May 18;(123):55655. doi: 10.3791/55655. PMID: 28570536; PMCID: PMC5603907. |
| Hoover B, Baena V, Kaelberer MM, Getaneh F, Chinchilla S, Bohórquez DV. The intestinal tuft cell nanostructure in 3D. Sci Rep. 2017 May 10;7(1):1652. doi: 10.1038/s41598-017-01520-x. PMID: 28490731; PMCID: PMC5431925. |
| Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC. Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunol. 2017 May;10(3):829. doi: 10.1038/mi.2017.29. PMID: 28435155. |
| Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nat Immunol. 2017 May;18(5):541-551. doi: 10.1038/ni.3690. Epub 2017 Mar 13. Erratum in: Nat Immunol. 2017 Jul 19;18(8):951. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1270. PMID: 28288099; PMCID: PMC5395345. |
| Arnold JW, Monteagudo-Mera A, Altermann E, Cadenas MB, Thompson AL, Azcarate-Peril MA. Genome Sequences of Potential Probiotic Lactobacillus rhamnosus Isolates from Human Infants. Genome Announc. 2017 Apr 6;5(14):e00107-17. doi: 10.1128/genomeA.00107-17. PMID: 28385840; PMCID: PMC5383888. |
| Rusin S, Covey S, Perjar I, Hollyfield J, Speck O, Woodward K, Woosley JT, Dellon ES. Determination of esophageal eosinophil counts and other histologic features of eosinophilic esophagitis by pathology trainees is highly accurate. Hum Pathol. 2017 Apr;62:50-55. doi: 10.1016/j.humpath.2016.12.017. Epub 2016 Dec 30. PMID: 28041975; PMCID: PMC5392430. |
| Ritchie LE, Taddeo SS, Weeks BR, Carroll RJ, Dykes L, Rooney LW, Turner ND. Impact of Novel Sorghum Bran Diets on DSS-Induced Colitis. Nutrients. 2017 Mar 27;9(4):330. doi: 10.3390/nu9040330. PMID: 28346392; PMCID: PMC5409669. |
| Chiaro TR, Soto R, Zac Stephens W, Kubinak JL, Petersen C, Gogokhia L, Bell R, Delgado JC, Cox J, Voth W, Brown J, Stillman DJ, O'Connell RM, Tebo AE, Round JL. A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice. Sci Transl Med. 2017 Mar 8;9(380):eaaf9044. doi: 10.1126/scitranslmed.aaf9044. Erratum in: Sci Transl Med. 2017 May 3;9(388): PMID: 28275154; PMCID: PMC5994919. |
| Furquim CP, Soares GM, Ribeiro LL, Azcarate-Peril MA, Butz N, Roach J, Moss K, Bonfim C, Torres-Pereira CC, Teles FR. The Salivary Microbiome and Oral Cancer Risk: a Pilot Study in Fanconi Anemia. J Dent Res. 2017 Mar;96(3):292-299. doi: 10.1177/0022034516678169. Epub 2016 Nov 13. PMID: 27827319; PMCID: PMC5298391. |
| Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC. Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease. Mucosal Immunol. 2017 Mar;10(2):395-407. doi: 10.1038/mi.2016.63. Epub 2016 Jul 20. PMID: 27435107; PMCID: PMC5250616. |
| Stepper P, Kungulovski G, Jurkowska RZ, Chandra T, Krueger F, Reinhardt R, Reik W, Jeltsch A, Jurkowski TP. Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase. Nucleic Acids Res. 2017 Feb 28;45(4):1703-1713. doi: 10.1093/nar/gkw1112. PMID: 27899645; PMCID: PMC5389507. |
| Ren NSX, Ji M, Tokar EJ, Busch EL, Xu X, Lewis D, Li X, Jin A, Zhang Y, Wu WKK, Huang W, Li L, Fargo DC, Keku TO, Sandler RS, Li X. Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development. Curr Biol. 2017 Feb 20;27(4):483-494. doi: 10.1016/j.cub.2016.12.047. Epub 2017 Feb 2. PMID: 28162896; PMCID: PMC5319916. |
| Peck BC, Mah AT, Pitman WA, Ding S, Lund PK, Sethupathy P. Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status. J Biol Chem. 2017 Feb 17;292(7):2586-2600. doi: 10.1074/jbc.M116.770099. Epub 2017 Jan 4. PMID: 28053090; PMCID: PMC5314158. |
| Dellon ES, Veerappan R, Selitsky SR, Parker JS, Higgins LL, Beitia R, Genta RM, Lash RH. A Gene Expression Panel is Accurate for Diagnosis and Monitoring Treatment of Eosinophilic Esophagitis in Adults. Clin Transl Gastroenterol. 2017 Feb 9;8(2):e74. doi: 10.1038/ctg.2017.2. PMID: 28181994; PMCID: PMC5387749. |
| Kechele DO, Blue RE, Zwarycz B, Espenschied ST, Mah AT, Siegel MB, Perou CM, Ding S, Magness ST, Lund PK, Caron KM. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017 Feb 1;127(2):593-607. doi: 10.1172/JCI87588. Epub 2017 Jan 17. PMID: 28094771; PMCID: PMC5272174. |
| Asher GN, Xie Y, Moaddel R, Sanghvi M, Dossou KS, Kashuba AD, Sandler RS, Hawke RL. Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers. J Clin Pharmacol. 2017 Feb;57(2):185-193. doi: 10.1002/jcph.806. Epub 2016 Sep 6. PMID: 27503249; PMCID: PMC5233601. |
| Cheong J, Galanko JA, Arora S, Cabezas J, Ndugga NJ, Lucey MR, Hayashi PH, Barritt AS, Bataller R. Reduced impact of renal failure on the outcome of patients with alcoholic liver disease undergoing liver transplantation. Liver Int. 2017 Feb;37(2):290-298. doi: 10.1111/liv.13182. Epub 2016 Jul 4. PMID: 27258535; PMCID: PMC5136341. |
| Azcarate-Peril MA, Ritter AJ, Savaiano D, Monteagudo-Mera A, Anderson C, Magness ST, Klaenhammer TR. Impact of short-chain galactooligosaccharides on the gut microbiome of lactose-intolerant individuals. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E367-E375. doi: 10.1073/pnas.1606722113. Epub 2017 Jan 3. PMID: 28049818; PMCID: PMC5255593. |
| Jin Y, Blikslager AT. Intestinal Ischemia-Reperfusion: Rooting for the SOCS? Dig Dis Sci. 2017 Jan;62(1):4-6. doi: 10.1007/s10620-016-4328-6. PMID: 27830407; PMCID: PMC5218974. |
| Wolf WA, Piazza NA, Gebhart JH, Rusin S, Covey S, Higgins LL, Beitia R, Speck O, Woodward K, Cotton CC, Runge TM, Eluri S, Woosley JT, Shaheen NJ, Dellon ES. Association Between Body Mass Index and Clinical and Endoscopic Features of Eosinophilic Esophagitis. Dig Dis Sci. 2017 Jan;62(1):143-149. doi: 10.1007/s10620-016-4357-1. Epub 2016 Oct 24. PMID: 27778205; PMCID: PMC5218962. |
| Romano-Keeler J, Azcarate-Peril MA, Weitkamp JH, Slaughter JC, McDonald WH, Meng S, Latuga MS, Wynn JL. Oral colostrum priming shortens hospitalization without changing the immunomicrobial milieu. J Perinatol. 2017 Jan;37(1):36-41. doi: 10.1038/jp.2016.161. Epub 2016 Sep 29. PMID: 27684425; PMCID: PMC5215726. |
| Herfarth HH, Jackson S, Schliebe BG, Martin C, Ivanova A, Anton K, Sandler RS, Long MD, Isaacs KL, Osterman MT, Sands BE, Higgins PD, Lewis JD. Investigator-Initiated IBD Trials in the United States: Facts, Obstacles, and Answers. Inflamm Bowel Dis. 2017 Jan;23(1):14-22. doi: 10.1097/MIB.0000000000000907. PMID: 27598744; PMCID: PMC5177501. |
| Huang MC, Douillet C, Su M, Zhou K, Wu T, Chen W, Galanko JA, Drobná Z, Saunders RJ, Martin E, Fry RC, Jia W, Stýblo M. Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure. Arch Toxicol. 2017 Jan;91(1):189-202. doi: 10.1007/s00204-016-1676-0. Epub 2016 Feb 16. PMID: 26883664; PMCID: PMC4987274. |
| Jeffries CD, Perkins DO, Chandler SD, Stark T, Yeo E, Addington J, Bearden CE, Cadenhead KS, Cannon TD, Cornblatt BA, Mathalon DH, McGlashan TH, Seidman LJ, Walker EF, Woods SW, Glatt SJ, Tsuang M. Insights into psychosis risk from leukocyte microRNA expression. Transl Psychiatry. 2016 Dec 13;6(12):e981. doi: 10.1038/tp.2016.148. PMID: 27959328; PMCID: PMC5290334. |
| Winston JA, Thanissery R, Montgomery SA, Theriot CM. Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291. J Vis Exp. 2016 Dec 10;(118):54850. doi: 10.3791/54850. PMID: 28060346; PMCID: PMC5226375. |
| Lundgren D, Rutegård J, Eklöf V, Palmqvist R, Karling P. Patients with longstanding ulcerative colitis in remission do not have more irritable bowel syndrome-like symptoms than controls. BMC Gastroenterol. 2016 Nov 24;16(1):139. doi: 10.1186/s12876-016-0553-x. PMID: 27881072; PMCID: PMC5121960. |
| Mottawea W, Chiang CK, Mühlbauer M, Starr AE, Butcher J, Abujamel T, Deeke SA, Brandel A, Zhou H, Shokralla S, Hajibabaei M, Singleton R, Benchimol EI, Jobin C, Mack DR, Figeys D, Stintzi A. Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohn's disease. Nat Commun. 2016 Nov 23;7:13419. doi: 10.1038/ncomms13419. PMID: 27876802; PMCID: PMC5122959. |
| Yan J, Herzog JW, Tsang K, Brennan CA, Bower MA, Garrett WS, Sartor BR, Aliprantis AO, Charles JF. Gut microbiota induce IGF-1 and promote bone formation and growth. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7554-E7563. doi: 10.1073/pnas.1607235113. Epub 2016 Nov 7. PMID: 27821775; PMCID: PMC5127374. |
| Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, Maeda N, Karumanchi SA, Smithies O, Takahashi N. Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13450-13455. doi: 10.1073/pnas.1614947113. Epub 2016 Nov 7. PMID: 27821757; PMCID: PMC5127378. |
| Twitchell EL, Tin C, Wen K, Zhang H, Becker-Dreps S, Azcarate-Peril MA, Vilchez S, Li G, Ramesh A, Weiss M, Lei S, Bui T, Yang X, Schultz-Cherry S, Yuan L. Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs. Gut Pathog. 2016 Nov 8;8:51. doi: 10.1186/s13099-016-0136-y. PMID: 27826359; PMCID: PMC5100090. |
| Ziegler A, Gonzalez L, Blikslager A. Large Animal Models: The Key to Translational Discovery in Digestive Disease Research. Cell Mol Gastroenterol Hepatol. 2016 Nov;2(6):716-724. doi: 10.1016/j.jcmgh.2016.09.003. PMID: 28090566; PMCID: PMC5235339. |
| Meliopoulos VA, Marvin SA, Freiden P, Moser LA, Nighot P, Ali R, Blikslager A, Reddivari M, Heath RJ, Koci MD, Schultz-Cherry S. Oral Administration of Astrovirus Capsid Protein Is Sufficient To Induce Acute Diarrhea In Vivo. mBio. 2016 Nov 1;7(6):e01494-16. doi: 10.1128/mBio.01494-16. PMID: 27803180; PMCID: PMC5090040. |
| Weaver KN, Kappelman MD, Sandler RS, Martin CF, Chen W, Anton K, Long MD. Variation in Care of Inflammatory Bowel Diseases Patients in Crohn's and Colitis Foundation of America Partners: Role of Gastroenterologist Practice Setting in Disease Outcomes and Quality Process Measures. Inflamm Bowel Dis. 2016 Nov;22(11):2672-2677. doi: 10.1097/MIB.0000000000000933. PMID: 27755268; PMCID: PMC5278899. |
| Abdalla MI, Sandler RS, Kappelman MD, Martin CF, Chen W, Anton K, Long MD. The Impact of Ostomy on Quality of Life and Functional Status of Crohn's Disease Patients. Inflamm Bowel Dis. 2016 Nov;22(11):2658-2664. doi: 10.1097/MIB.0000000000000930. PMID: 27661669; PMCID: PMC5087602. |
| Arnold JW, Roach J, Azcarate-Peril MA. Emerging Technologies for Gut Microbiome Research. Trends Microbiol. 2016 Nov;24(11):887-901. doi: 10.1016/j.tim.2016.06.008. Epub 2016 Jul 15. PMID: 27426971; PMCID: PMC5074899. |
| Emami-Khoyi A, Hartley DA, Ross JG, Murphy EC, Paterson AM, Cruickshank RH, Else TA. Complete mitochondrial genome of the stoat (Mustela erminea) and New Zealand fur seal (Arctocephalus forsteri) and their significance for mammalian phylogeny. Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Nov;27(6):4597-4599. doi: 10.3109/19401736.2015.1101542. Epub 2016 May 31. Erratum in: Mitochondrial DNA A DNA Mapp Seq Anal. 2018 Jul;29(5):816. PMID: 27246241. |
| Liang J, Huang HI, Benzatti FP, Karlsson AB, Zhang JJ, Youssef N, Ma A, Hale LP, Hammer GE. Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88. Cell Rep. 2016 Oct 25;17(5):1330-1343. doi: 10.1016/j.celrep.2016.09.091. PMID: 27783947; PMCID: PMC5123685. |
| Blum AE, Venkitachalam S, Guo Y, Kieber-Emmons AM, Ravi L, Chandar AK, Iyer PG, Canto MI, Wang JS, Shaheen NJ, Barnholtz-Sloan JS, Markowitz SD, Willis JE, Shyr Y, Chak A, Varadan V, Guda K. RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas. Cancer Res. 2016 Oct 1;76(19):5628-5633. doi: 10.1158/0008-5472.CAN-16-0979. Epub 2016 Aug 8. PMID: 27503924; PMCID: PMC5050127. |
| Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, Lippman HR, Sikaroodi M, Brown RR, Bajaj JS. Gut microbiota drive the development of neuroinflammatory response in cirrhosis in mice. Hepatology. 2016 Oct;64(4):1232-48. doi: 10.1002/hep.28696. Epub 2016 Jul 29. PMID: 27339732; PMCID: PMC5033692. |
| Wells MA, Vendrov KC, Edin ML, Ferslew BC, Zha W, Nguyen BK, Church RJ, Lih FB, DeGraff LM, Brouwer KL, Barritt AS 4th, Zeldin DC, Lee CR. Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis. Prostaglandins Other Lipid Mediat. 2016 Sep;125:19-29. doi: 10.1016/j.prostaglandins.2016.07.002. Epub 2016 Jul 9. PMID: 27401401; PMCID: PMC5035202. |
| Henning SJ, von Furstenberg RJ. GI stem cells - new insights into roles in physiology and pathophysiology. J Physiol. 2016 Sep 1;594(17):4769-79. doi: 10.1113/JP271663. Epub 2016 Apr 24. PMID: 27107928; PMCID: PMC4847377. |
| Kang DJ, Kakiyama G, Betrapally NS, Herzog J, Nittono H, Hylemon PB, Zhou H, Carroll I, Yang J, Gillevet PM, Jiao C, Takei H, Pandak WM, Iida T, Heuman DM, Fan S, Fiehn O, Kurosawa T, Sikaroodi M, Sartor RB, Bajaj JS. Rifaximin Exerts Beneficial Effects Independent of its Ability to Alter Microbiota Composition. Clin Transl Gastroenterol. 2016 Aug 25;7(8):e187. doi: 10.1038/ctg.2016.44. PMID: 27560928; PMCID: PMC5543406. |
| Snider NT, Portney DA, Willcockson HH, Maitra D, Martin HC, Greenson JK, Omary MB. Ethanol and Acetaminophen Synergistically Induce Hepatic Aggregation and TCH346-Insensitive Nuclear Translocation of GAPDH. PLoS One. 2016 Aug 11;11(8):e0160982. doi: 10.1371/journal.pone.0160982. PMID: 27513663; PMCID: PMC4981434. |
| Simon JM, Davis JP, Lee SE, Schaner MR, Gipson GR, Weiser M, Sartor RB, Herfarth HH, Rahbar R, Sadiq TS, Koruda MJ, McGovern DP, Lieb JD, Mohlke KL, Furey TS, Sheikh SZ. Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses. Eur J Immunol. 2016 Aug;46(8):1912-25. doi: 10.1002/eji.201546237. Epub 2016 Jun 1. PMID: 27159132; PMCID: PMC5486994. |
| Brotherton CS, Martin CA, Long MD, Kappelman MD, Sandler RS. Avoidance of Fiber Is Associated With Greater Risk of Crohn's Disease Flare in a 6-Month Period. Clin Gastroenterol Hepatol. 2016 Aug;14(8):1130-6. doi: 10.1016/j.cgh.2015.12.029. Epub 2015 Dec 31. PMID: 26748217; PMCID: PMC4930425. |
| Li N, Pasricha S, Bulsiewicz WJ, Pruitt RE, Komanduri S, Wolfsen HC, Chmielewski GW, Corbett FS, Chang KJ, Shaheen NJ. Effects of preceding endoscopic mucosal resection on the efficacy and safety of radiofrequency ablation for treatment of Barrett's esophagus: results from the United States Radiofrequency Ablation Registry. Dis Esophagus. 2016 Aug;29(6):537-43. doi: 10.1111/dote.12386. Epub 2015 Jun 30. PMID: 26121935; PMCID: PMC4977202. |
| Burk CM, Beitia R, Lund PK, Dellon ES. High rate of galactose- alpha-1,3-galactose sensitization in both eosinophilic esophagitis and patients undergoing upper endoscopy. Dis Esophagus. 2016 Aug;29(6):558-62. doi: 10.1111/dote.12356. Epub 2015 Mar 23. PMID: 25809945; PMCID: PMC4580560. |
| Cotton CC, Baird D, Sandler RS, Long MD. Hormonal Contraception Use is Common Among Patients with Inflammatory Bowel Diseases and an Elevated Risk of Deep Vein Thrombosis. Inflamm Bowel Dis. 2016 Jul;22(7):1631-8. doi: 10.1097/MIB.0000000000000800. PMID: 27306071; PMCID: PMC5064836. |
| Dellon ES, Higgins LL, Beitia R, Rusin S, Woosley JT, Veerappan R, Selitsky SR, Parker JS, Genta RM, Lash RH, Aranda R, Peach RJ, Grimm M. Prospective assessment of serum periostin as a biomarker for diagnosis and monitoring of eosinophilic oesophagitis. Aliment Pharmacol Ther. 2016 Jul;44(2):189-97. doi: 10.1111/apt.13672. Epub 2016 May 18. PMID: 27193351; PMCID: PMC4907797. |
| Shafa S, Shaheen NJ. Buried Barrett's Esophagus-a Sheep in Sheep's Clothing. J Gastrointest Surg. 2016 Jul;20(7):1281-3. doi: 10.1007/s11605-016-3165-4. Epub 2016 May 16. PMID: 27184674. |
| Arvanitis M, DeWalt DA, Martin CF, Long MD, Chen W, Jaeger B, Sandler RS, Kappelman MD. Patient-Reported Outcomes Measurement Information System in Children with Crohn's Disease. J Pediatr. 2016 Jul;174:153-159.e2. doi: 10.1016/j.jpeds.2016.03.069. Epub 2016 May 2. PMID: 27157449; PMCID: PMC5157125. |
| Wu C, Sartor RB, Huang K, Tonkonogy SL. Transient activation of mucosal effector immune responses by resident intestinal bacteria in normal hosts is regulated by interleukin-10 signalling. Immunology. 2016 Jul;148(3):304-14. doi: 10.1111/imm.12612. PMID: 27147411; PMCID: PMC4913287. |
| Arsene D, Farooq O, Bataller R. New therapeutic targets in alcoholic hepatitis. Hepatol Int. 2016 Jul;10(4):538-52. doi: 10.1007/s12072-015-9701-6. Epub 2016 Apr 12. PMID: 27072540; PMCID: PMC5455987. |
| Peery AF, Keku TO, Martin CF, Eluri S, Runge T, Galanko JA, Sandler RS. Distribution and Characteristics of Colonic Diverticula in a United States Screening Population. Clin Gastroenterol Hepatol. 2016 Jul;14(7):980-985.e1. doi: 10.1016/j.cgh.2016.01.020. Epub 2016 Feb 9. PMID: 26872402; PMCID: PMC4912930. |
| Kochar B, Aldridge M, Cook SF, Bright R, Mallette M, Moniz H, Shah SA, LeLeiko NS, Shapiro J, Sands BE, Chen W, Jaeger E, Galanko J, Long MD, Martin CF, Sandler RS, Kappelman MD. Achieving Synergy: Linking an Internet-Based Inflammatory Bowel Disease Cohort to a Community-Based Inception Cohort and Multicentered Cohort in Inflammatory Bowel Disease. J Med Internet Res. 2016 Jun 3;18(6):e124. doi: 10.2196/jmir.5655. PMID: 27261008; PMCID: PMC4912687. |
| Lewis CM, Wolf WA, Xun P, Sandler RS, He K. Racial differences in dietary changes and quality of life after a colorectal cancer diagnosis: a follow-up of the Study of Outcomes in Colorectal Cancer Survivors cohort. Am J Clin Nutr. 2016 Jun;103(6):1523-30. doi: 10.3945/ajcn.115.126276. Epub 2016 Apr 20. PMID: 27099251; PMCID: PMC4880997. |
| Gaines LS, Slaughter JC, Horst SN, Schwartz DA, Beaulieu DB, Haman KL, Wang L, Martin CF, Long MD, Sandler RS, Kappelman MD. Association Between Affective- Cognitive Symptoms of Depression and Exacerbation of Crohn's Disease. Am J Gastroenterol. 2016 Jun;111(6):864-70. doi: 10.1038/ajg.2016.98. Epub 2016 Apr 5. PMID: 27045927; PMCID: PMC4965803. |
| Geisz M, Ha C, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS, Long MD. Medication Utilization and the Impact of Continued Corticosteroid Use on Patient-reported Outcomes in Older Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 Jun;22(6):1435-41. doi: 10.1097/MIB.0000000000000747. PMID: 26978725; PMCID: PMC4868778. |
| Crockett SD, Cirri HO, Kelapure R, Galanko JA, Martin CF, Dellon ES. Use of an Abdominal Compression Device in Colonoscopy: A Randomized, Sham-Controlled Trial. Clin Gastroenterol Hepatol. 2016 Jun;14(6):850-857.e3. doi: 10.1016/j.cgh.2015.12.039. Epub 2016 Jan 6. PMID: 26767313; PMCID: PMC4875866. |
| Chung AE, Sandler RS, Long MD, Ahrens S, Burris JL, Martin CF, Anton K, Robb A, Caruso TP, Jaeger EL, Chen W, Clark M, Myers K, Dobes A, Kappelman MD. Harnessing person-generated health data to accelerate patient-centered outcomes research: the Crohn's and Colitis Foundation of America PCORnet Patient Powered Research Network (CCFA Partners). J Am Med Inform Assoc. 2016 May;23(3):485-90. doi: 10.1093/jamia/ocv191. Epub 2016 Jan 28. PMID: 26911821; PMCID: PMC4901381. |
| Attayek PJ, Ahmad AA, Wang Y, Williamson I, Sims CE, Magness ST, Allbritton NL. In Vitro Polarization of Colonoids to Create an Intestinal Stem Cell Compartment. PLoS One. 2016 Apr 21;11(4):e0153795. doi: 10.1371/journal.pone.0153795. PMID: 27100890; PMCID: PMC4839657. |
| Richmond BW, Brucker RM, Han W, Du RH, Zhang Y, Cheng DS, Gleaves L, Abdolrasulnia R, Polosukhina D, Clark PE, Bordenstein SR, Blackwell TS, Polosukhin VV. Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency. Nat Commun. 2016 Apr 5;7:11240. doi: 10.1038/ncomms11240. PMID: 27046438; PMCID: PMC4822073. |
| Qin Y, Sundaram S, Essaid L, Chen X, Miller SM, Yan F, Darr DB, Galanko JA, Montgomery SA, Major MB, Johnson GL, Troester MA, Makowski L. Weight loss reduces basal-like breast cancer through kinome reprogramming. Cancer Cell Int. 2016 Apr 1;16:26. doi: 10.1186/s12935-016-0300-y. PMID: 27042159; PMCID: PMC4818517. |
| Fromen CA, Rahhal TB, Robbins GR, Kai MP, Shen TW, Luft JC, DeSimone JM. Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells. Nanomedicine. 2016 Apr;12(3):677-687. doi: 10.1016/j.nano.2015.11.002. Epub 2015 Dec 1. PMID: 26656533; PMCID: PMC4839472. |
| Berkoff DJ, Kallianos SA, Eskildsen SM, Weinhold PS. Use of an IL1-receptor antagonist to prevent the progression of tendinopathy in a rat model. J Orthop Res. 2016 Apr;34(4):616-22. doi: 10.1002/jor.23057. Epub 2015 Dec 29. PMID: 26418607. |
| Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WHW, DiDonato JA, Brown JM, Lusis AJ, Hazen SL. Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk. Cell. 2016 Mar 24;165(1):111-124. doi: 10.1016/j.cell.2016.02.011. Epub 2016 Mar 10. PMID: 26972052; PMCID: PMC4862743. |
| Cozzo AJ, Sundaram S, Zattra O, Qin Y, Freemerman AJ, Essaid L, Darr DB, Montgomery SA, McNaughton KK, Ezzell JA, Galanko JA, Troester MA, Makowski L. cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer. Springerplus. 2016 Mar 19;5:348. doi: 10.1186/s40064-016-1920-3. PMID: 27057482; PMCID: PMC4799044. |
| Fung TC, Bessman NJ, Hepworth MR, Kumar N, Shibata N, Kobuley D, Wang K, Ziegler CGK, Goc J, Shima T, Umesaki Y, Sartor RB, Sullivan KV, Lawley TD, Kunisawa J, Kiyono H, Sonnenberg GF. Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism. Immunity. 2016 Mar 15;44(3):634-646. doi: 10.1016/j.immuni.2016.02.019. PMID: 26982365; PMCID: PMC4845739. |
| Samsa LA, Fleming N, Magness S, Qian L, Liu J. Isolation and Characterization of Single Cells from Zebrafish Embryos. J Vis Exp. 2016 Mar 12;(109):53877. doi: 10.3791/53877. PMID: 27022828; PMCID: PMC4828977. |
| Grogan KE, McGinnis GJ, Sauther ML, Cuozzo FP, Drea CM. Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications. BMC Genomics. 2016 Mar 8;17:204. doi: 10.1186/s12864-016-2503-y. PMID: 26957424; PMCID: PMC4782575. |
| Murphy CC, Sandler RS, Grubber JM, Johnson MR, Fisher DA. Underuse and Overuse of Colonoscopy for Repeat Screening and Surveillance in the Veterans Health Administration. Clin Gastroenterol Hepatol. 2016 Mar;14(3):436-444.e1. doi: 10.1016/j.cgh.2015.10.008. Epub 2015 Oct 19. PMID: 26492843; PMCID: PMC4761454. |
| Hod K, Ringel-Kulka T, Martin CF, Maharshak N, Ringel Y. High-sensitive C-Reactive Protein as a Marker for Inflammation in Irritable Bowel Syndrome. J Clin Gastroenterol. 2016 Mar;50(3):227-32. doi: 10.1097/MCG.0000000000000327. PMID: 25930973; PMCID: PMC4950940. |
| Byrne JD, Jajja MR, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2200-5. doi: 10.1073/pnas.1600421113. Epub 2016 Feb 8. PMID: 26858448; PMCID: PMC4776454. |
| Villarino NF, LeCleir GR, Denny JE, Dearth SP, Harding CL, Sloan SS, Gribble JL, Campagna SR, Wilhelm SW, Schmidt NW. Composition of the gut microbiota modulates the severity of malaria. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2235-40. doi: 10.1073/pnas.1504887113. Epub 2016 Feb 8. PMID: 26858424; PMCID: PMC4776451. |
| Long MD, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS. Role of Nonsteroidal Anti-Inflammatory Drugs in Exacerbations of Inflammatory Bowel Disease. J Clin Gastroenterol. 2016 Feb;50(2):152-6. doi: 10.1097/MCG.0000000000000421. PMID: 26485106; PMCID: PMC4703528. |
| Mideo N, Bailey JA, Hathaway NJ, Ngasala B, Saunders DL, Lon C, Kharabora O, Jamnik A, Balasubramanian S, Björkman A, Mårtensson A, Meshnick SR, Read AF, Juliano JJ. A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections. Evol Med Public Health. 2016 Jan 27;2016(1):21-36. doi: 10.1093/emph/eov036. PMID: 26817485; PMCID: PMC4753362. |
| Randell RL, Gulati AS, Cook SF, Martin CF, Chen W, Jaeger EL, Schoenborn AA, Basta PV, Dejong H, Luo J, Gallant M, Sandler RS, Long MD, Kappelman MD. Collecting Biospecimens From an Internet-Based Prospective Cohort Study of Inflammatory Bowel Disease (CCFA Partners): A Feasibility Study. JMIR Res Protoc. 2016 Jan 5;5(1):e3. doi: 10.2196/resprot.5171. PMID: 26732016; PMCID: PMC4719077. |
| Farooq MO, Bataller R. Pathogenesis and Management of Alcoholic Liver Disease. Dig Dis. 2016;34(4):347-55. doi: 10.1159/000444545. Epub 2016 May 11. PMID: 27170388; PMCID: PMC4910523. |
| Monteagudo-Mera A, Arthur JC, Jobin C, Keku T, Bruno-Barcena JM, Azcarate- Peril MA. High purity galacto-oligosaccharides enhance specific Bifidobacterium species and their metabolic activity in the mouse gut microbiome. Benef Microbes. 2016;7(2):247-64. doi: 10.3920/BM2015.0114. Epub 2016 Feb 3. PMID: 26839072; PMCID: PMC4974821. |
| Medina E, Pérez-Díaz IM, Breidt F, Hayes J, Franco W, Butz N, Azcarate- Peril MA. Bacterial Ecology of Fermented Cucumber Rising pH Spoilage as Determined by Nonculture-Based Methods. J Food Sci. 2016 Jan;81(1):M121-9. doi: 10.1111/1750-3841.13158. Epub 2015 Nov 25. PMID: 26605993; PMCID: PMC4973622. |
| Dagher SF, Bruno-Bárcena JM. A novel N-terminal region of the membrane β-hexosyltransferase: its role in secretion of soluble protein by Pichia pastoris. Microbiology (Reading). 2016 Jan;162(1):23-34. doi: 10.1099/mic.0.000211. Epub 2015 Nov 9. PMID: 26552922; PMCID: PMC5974927. |
| Busch EL, Keku TO, Richardson DB, Cohen SM, Eberhard DA, Avery CL, Sandler RS. Evaluating markers of epithelial-mesenchymal transition to identify cancer patients at risk for metastatic disease. Clin Exp Metastasis. 2016 Jan;33(1):53-62. doi: 10.1007/s10585-015-9757-7. Epub 2015 Oct 27. PMID: 26507436; PMCID: PMC4742430. |
| Herfarth HH, Kappelman MD, Long MD, Isaacs KL. Use of Methotrexate in the Treatment of Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2016 Jan;22(1):224-33. doi: 10.1097/MIB.0000000000000589. PMID: 26457382; PMCID: PMC4679484. |
| Dellon ES, Cotton CC, Gebhart JH, Higgins LL, Beitia R, Woosley JT, Shaheen NJ. Accuracy of the Eosinophilic Esophagitis Endoscopic Reference Score in Diagnosis and Determining Response to Treatment. Clin Gastroenterol Hepatol. 2016 Jan;14(1):31-9. doi: 10.1016/j.cgh.2015.08.040. Epub 2015 Sep 25. Erratum in: Clin Gastroenterol Hepatol. 2016 Jun;14 (6):919. PMID: 26404868; PMCID: PMC4690779. |
| Dellon ES, Gebhart JH, Higgins LL, Hathorn KE, Woosley JT, Shaheen NJ. The esophageal biopsy "pull" sign: a highly specific and treatment-responsive endoscopic finding in eosinophilic esophagitis (with video). Gastrointest Endosc. 2016 Jan;83(1):92-100. doi: 10.1016/j.gie.2015.05.046. Epub 2015 Jul 2. PMID: 26142556; PMCID: PMC4691559. |
| Jensen ET, Martin CF, Kappelman MD, Dellon ES. Prevalence of Eosinophilic Gastritis, Gastroenteritis, and Colitis: Estimates From a National Administrative Database. J Pediatr Gastroenterol Nutr. 2016 Jan;62(1):36-42. doi: 10.1097/MPG.0000000000000865. PMID: 25988554; PMCID: PMC4654708. |
| Wang H, Iwasaki M, Haiman CA, Kono S, Wilkens LR, Keku TO, Berndt SI, Tsugane S, Le Marchand L. Interaction between Red Meat Intake and NAT2 Genotype in Increasing the Risk of Colorectal Cancer in Japanese and African Americans. PLoS One. 2015 Dec 18;10(12):e0144955. doi: 10.1371/journal.pone.0144955. PMID: 26683305; PMCID: PMC4684304. |
| Lubamba BA, Jones LC, O'Neal WK, Boucher RC, Ribeiro CM. X-Box-Binding Protein 1 and Innate Immune Responses of Human Cystic Fibrosis Alveolar Macrophages. Am J Respir Crit Care Med. 2015 Dec 15;192(12):1449-61. doi: 10.1164/rccm.201504-0657OC. PMID: 26331676; PMCID: PMC4731720. |
| Peery AF, Martin CF, Levinson SE, Sandler RS. Colonic Diverticula Are Not Associated With an Increased Risk of Colorectal Adenomas. Am J Gastroenterol. 2015 Dec;110(12):1694-7. doi: 10.1038/ajg.2015.359. Epub 2015 Nov 3. PMID: 26526082; PMCID: PMC4765899. |
| Becker-Dreps S, Allali I, Monteagudo A, Vilchez S, Hudgens MG, Rogawski ET, Carroll IM, Zambrana LE, Espinoza F, Azcarate-Peril MA. Gut Microbiome Composition in Young Nicaraguan Children During Diarrhea Episodes and Recovery. Am J Trop Med Hyg. 2015 Dec;93(6):1187-93. doi: 10.4269/ajtmh.15-0322. Epub 2015 Sep 8. PMID: 26350452; PMCID: PMC4674233. |
| Wolf WA, Pasricha S, Cotton C, Li N, Triadafilopoulos G, Muthusamy VR, Chmielewski GW, Corbett FS, Camara DS, Lightdale CJ, Wolfsen H, Chang KJ, Overholt BF, Pruitt RE, Ertan A, Komanduri S, Infantolino A, Rothstein RI, Shaheen NJ. Incidence of Esophageal Adenocarcinoma and Causes of Mortality After Radiofrequency Ablation of Barrett's Esophagus. Gastroenterology. 2015 Dec;149(7):1752-1761.e1. doi: 10.1053/j.gastro.2015.08.048. Epub 2015 Aug 29. PMID: 26327132; PMCID: PMC4785890. |
| Kleiman SC, Watson HJ, Bulik-Sullivan EC, Huh EY, Tarantino LM, Bulik CM, Carroll IM. The Intestinal Microbiota in Acute Anorexia Nervosa and During Renourishment: Relationship to Depression, Anxiety, and Eating Disorder Psychopathology. Psychosom Med. 2015 Nov-Dec;77(9):969-81. doi: 10.1097/PSY.0000000000000247. PMID: 26428446; PMCID: PMC4643361. |
| Roche KC, Gracz AD, Liu XF, Newton V, Akiyama H, Magness ST. SOX9 maintains reserve stem cells and preserves radioresistance in mouse small intestine. Gastroenterology. 2015 Nov;149(6):1553-1563.e10. doi: 10.1053/j.gastro.2015.07.004. Epub 2015 Jul 11. PMID: 26170137; PMCID: PMC4709179. |
| Kubinak JL, Stephens WZ, Soto R, Petersen C, Chiaro T, Gogokhia L, Bell R, Ajami NJ, Petrosino JF, Morrison L, Potts WK, Jensen PE, O'Connell RM, Round JL. MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection. Nat Commun. 2015 Oct 23;6:8642. doi: 10.1038/ncomms9642. PMID: 26494419; PMCID: PMC4621775. |
| Stasulli NM, Eichelberger KR, Price PA, Pechous RD, Montgomery SA, Parker JS, Goldman WE. Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague. mBio. 2015 Oct 13;6(5):e01530-15. doi: 10.1128/mBio.01530-15. PMID: 26463167; PMCID: PMC4620470. |
| Bahr SM, Tyler BC, Wooldridge N, Butcher BD, Burns TL, Teesch LM, Oltman CL, Azcarate-Peril MA, Kirby JR, Calarge CA. Use of the second-generation antipsychotic, risperidone, and secondary weight gain are associated with an altered gut microbiota in children. Transl Psychiatry. 2015 Oct 6;5(10):e652. doi: 10.1038/tp.2015.135. PMID: 26440540; PMCID: PMC4930121. |
| Oikawa T, Wauthier E, Dinh TA, Selitsky SR, Reyna-Neyra A, Carpino G, Levine R, Cardinale V, Klimstra D, Gaudio E, Alvaro D, Carrasco N, Sethupathy P, Reid LM. Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells. Nat Commun. 2015 Oct 6;6:8070. doi: 10.1038/ncomms9070. PMID: 26437858; PMCID: PMC4600730. |
| Wolf WA, Cotton CC, Green DJ, Hughes JT, Woosley JT, Shaheen NJ, Dellon ES. Evaluation of Histologic Cutpoints for Treatment Response in Eosinophilic Esophagitis. J Gastroenterol Hepatol Res. 2015 Oct 1;4(10):1780-1787. doi: 10.17554/j.issn.2224-3992.2015.04.562. Epub 2015 Oct 21. PMID: 27110513; PMCID: PMC4838410. |
| Cotton CC, Duits LC, Wolf WA, Peery AF, Dellon ES, Bergman JJ, Shaheen NJ. Spatial predisposition of dysplasia in Barrett's esophagus segments: a pooled analysis of the SURF and AIM dysplasia trials. Am J Gastroenterol. 2015 Oct;110(10):1412-9. doi: 10.1038/ajg.2015.263. Epub 2015 Sep 8. PMID: 26346864; PMCID: PMC4785998. |
| Moffitt RA, Marayati R, Flate EL, Volmar KE, Loeza SG, Hoadley KA, Rashid NU, Williams LA, Eaton SC, Chung AH, Smyla JK, Anderson JM, Kim HJ, Bentrem DJ, Talamonti MS, Iacobuzio-Donahue CA, Hollingsworth MA, Yeh JJ. Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma. Nat Genet. 2015 Oct;47(10):1168-78. doi: 10.1038/ng.3398. Epub 2015 Sep 7. PMID: 26343385; PMCID: PMC4912058. |
| Santoro MA, Blue RE, Andres SF, Mah AT, Van Landeghem L, Lund PK. Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon. Am J Physiol Gastrointest Liver Physiol. 2015 Oct 1;309(7):G578-89. doi: 10.1152/ajpgi.00189.2015. Epub 2015 Aug 6. PMID: 26251471; PMCID: PMC4593818. |
| Ellermann M, Huh EY, Liu B, Carroll IM, Tamayo R, Sartor RB. Adherent- Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis. Infect Immun. 2015 Oct;83(10):4068-80. doi: 10.1128/IAI.00904-15. Epub 2015 Jul 27. PMID: 26216423; PMCID: PMC4567620. |
| Pasricha S, Cotton C, Hathorn KE, Li N, Bulsiewicz WJ, Wolf WA, Muthusamy VR, Komanduri S, Wolfsen HC, Pruitt RE, Ertan A, Chmielewski GW, Shaheen NJ. Effects of the Learning Curve on Efficacy of Radiofrequency Ablation for Barrett's Esophagus. Gastroenterology. 2015 Oct;149(4):890-6.e2. doi: 10.1053/j.gastro.2015.06.012. Epub 2015 Jun 25. PMID: 26116806; PMCID: PMC4584171. |
| Corzo-Martinez M, Luscher A, de Las Rivas B, Muñoz R, Moreno FJ. Valorization of Cheese and Tofu Whey through Enzymatic Synthesis of Lactosucrose. PLoS One. 2015 Sep 25;10(9):e0139035. doi: 10.1371/journal.pone.0139035. PMID: 26406885; PMCID: PMC4583474. |
| Peery AF, Sandler RS, Galanko JA, Bresalier RS, Figueiredo JC, Ahnen DJ, Barry EL, Baron JA. Risk Factors for Hemorrhoids on Screening Colonoscopy. PLoS One. 2015 Sep 25;10(9):e0139100. doi: 10.1371/journal.pone.0139100. PMID: 26406337; PMCID: PMC4583402. |
| Ringel-Kulka T, Choi CH, Temas D, Kim A, Maier DM, Scott K, Galanko JA, Ringel Y. Altered Colonic Bacterial Fermentation as a Potential Pathophysiological Factor in Irritable Bowel Syndrome. Am J Gastroenterol. 2015 Sep;110(9):1339-46. doi: 10.1038/ajg.2015.220. Epub 2015 Aug 25. PMID: 26303129; PMCID: PMC4983766. |
| Dellon ES, Rusin S, Gebhart JH, Covey S, Speck O, Woodward K, Higgins LL, Beitia R, Madanick RD, Levinson S, Woosley JT, Shaheen NJ. A Clinical Prediction Tool Identifies Cases of Eosinophilic Esophagitis Without Endoscopic Biopsy: A Prospective Study. Am J Gastroenterol. 2015 Sep;110(9):1347-54. doi: 10.1038/ajg.2015.239. Epub 2015 Aug 25. PMID: 26303128; PMCID: PMC4586067. |
| Mack CD, Brookhart MA, Glynn RJ, Meyer AM, Carpenter WR, Sandler RS, Stürmer T. Comparative Effectiveness of Oxaliplatin Versus 5-flourouricil in Older Adults: An Instrumental Variable Analysis. Epidemiology. 2015 Sep;26(5):690-9. doi: 10.1097/EDE.0000000000000355. PMID: 26196683; PMCID: PMC4906444. |
| Peck BC, Weiser M, Lee SE, Gipson GR, Iyer VB, Sartor RB, Herfarth HH, Long MD, Hansen JJ, Isaacs KL, Trembath DG, Rahbar R, Sadiq TS, Furey TS, Sethupathy P, Sheikh SZ. MicroRNAs Classify Different Disease Behavior Phenotypes of Crohn's Disease and May Have Prognostic Utility. Inflamm Bowel Dis. 2015 Sep;21(9):2178-87. doi: 10.1097/MIB.0000000000000478. PMID: 26164662; PMCID: PMC4603665. |
| Van Treuren W, Ponnusamy L, Brinkerhoff RJ, Gonzalez A, Parobek CM, Juliano JJ, Andreadis TG, Falco RC, Ziegler LB, Hathaway N, Keeler C, Emch M, Bailey JA, Roe RM, Apperson CS, Knight R, Meshnick SR. Variation in the Microbiota of Ixodes Ticks with Regard to Geography, Species, and Sex. Appl Environ Microbiol. 2015 Sep;81(18):6200-9. doi: 10.1128/AEM.01562-15. Epub 2015 Jul 6. PMID: 26150449; PMCID: PMC4542252. |
| Herfarth HH, Long MD, Isaacs KL. Use of Biologics in Pouchitis: A Systematic Review. J Clin Gastroenterol. 2015 Sep;49(8):647-54. doi: 10.1097/MCG.0000000000000367. PMID: 26084005; PMCID: PMC4532631. |
| Ji J, Zheng X, Forgues M, Yamashita T, Wauthier EL, Reid LM, Wen X, Song Y, Wei JS, Khan J, Thorgeirsson SS, Wang XW. Identification of microRNAs specific for epithelial cell adhesion molecule-positive tumor cells in hepatocellular carcinoma. Hepatology. 2015 Sep;62(3):829-40. doi: 10.1002/hep.27886. Epub 2015 Jun 30. PMID: 25953724; PMCID: PMC4549211. |
| Maharshak N, Ryu HS, Fan TJ, Onyiah JC, Schulz S, Otterbein SL, Wong R, Hansen JJ, Otterbein LE, Carroll IM, Plevy SE. Escherichia coli heme oxygenase modulates host innate immune responses. Microbiol Immunol. 2015 Aug;59(8):452-65. doi: 10.1111/1348-0421.12282. PMID: 26146866; PMCID: PMC4582649. |
| Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Mühlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, Ramsden DA, Davis BK, Ting JP. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nat Med. 2015 Aug;21(8):906-13. doi: 10.1038/nm.3908. Epub 2015 Jun 24. PMID: 26107252; PMCID: PMC4529369. |
| Tzanetakis GN, Azcarate-Peril MA, Zachaki S, Panopoulos P, Kontakiotis EG, Madianos PN, Divaris K. Comparison of Bacterial Community Composition of Primary and Persistent Endodontic Infections Using Pyrosequencing. J Endod. 2015 Aug;41(8):1226-33. doi: 10.1016/j.joen.2015.03.010. Epub 2015 Apr 21. PMID: 25906920; PMCID: PMC4578635. |
| Pasricha S, Li N, Bulsiewicz WJ, Rothstein RI, Infantolino A, Ertan A, Camara DS, Dellon ES, Triadafilopoulos G, Lightdale CJ, Madanick RD, Lyday WD, Muthusamy RV, Overholt BF, Shaheen NJ. Sex and race and/or ethnicity differences in patients undergoing radiofrequency ablation for Barrett's esophagus: results from the U.S. RFA Registry. Gastrointest Endosc. 2015 Aug;82(2):276-84. doi: 10.1016/j.gie.2015.01.015. Epub 2015 Apr 1. PMID: 25841575; PMCID: PMC4506693. |
| Seiler KM, Schenhals EL, von Furstenberg RJ, Allena BK, Smith BJ, Scaria D, Bresler MN, Dekaney CM, Henning SJ. Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage. Cell Tissue Res. 2015 Aug;361(2):427-38. doi: 10.1007/s00441-015-2111-1. Epub 2015 Feb 19. PMID: 25693894; PMCID: PMC4530061. |
| Henning SJ, Estes MK. Women in Science: Hints for Success. Gastroenterology. 2015 Jul;149(1):10-3. doi: 10.1053/j.gastro.2015.05.035. Epub 2015 May 27. PMID: 26021234; PMCID: PMC4949163. |
| Maharshak N, Huh EY, Paiboonrungruang C, Shanahan M, Thurlow L, Herzog J, Djukic Z, Orlando R, Pawlinski R, Ellermann M, Borst L, Patel S, Dotan I, Sartor RB, Carroll IM. Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2. Infect Immun. 2015 Jul;83(7):2762-70. doi: 10.1128/IAI.00425-15. Epub 2015 Apr 27. PMID: 25916983; PMCID: PMC4468563. |
| Noar J, Loveless T, Navarro-Herrero JL, Olson JW, Bruno-Bárcena JM. Aerobic Hydrogen Production via Nitrogenase in Azotobacter vinelandii CA6. Appl Environ Microbiol. 2015 Jul;81(13):4507-16. doi: 10.1128/AEM.00679-15. Epub 2015 Apr 24. PMID: 25911479; PMCID: PMC4475890. |
| Van Landeghem L, Santoro MA, Mah AT, Krebs AE, Dehmer JJ, McNaughton KK, Helmrath MA, Magness ST, Lund PK. IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations. FASEB J. 2015 Jul;29(7):2828-42. doi: 10.1096/fj.14-264010. Epub 2015 Apr 2. PMID: 25837582; PMCID: PMC4478798. |
| Gonzalez LM, Moeser AJ, Blikslager AT. Porcine models of digestive disease: the future of large animal translational research. Transl Res. 2015 Jul;166(1):12-27. doi: 10.1016/j.trsl.2015.01.004. Epub 2015 Jan 13. PMID: 25655839; PMCID: PMC4458388. |
| Ritchie LE, Taddeo SS, Weeks BR, Lima F, Bloomfield SA, Azcarate-Peril MA, Zwart SR, Smith SM, Turner ND. Space Environmental Factor Impacts upon Murine Colon Microbiota and Mucosal Homeostasis. PLoS One. 2015 Jun 17;10(6):e0125792. doi: 10.1371/journal.pone.0125792. PMID: 26083373; PMCID: PMC4470690. |
| Reina LD, Pérez-Díaz IM, Breidt F, Azcarate-Peril MA, Medina E, Butz N. Characterization of the microbial diversity in yacon spontaneous fermentation at 20 °C. Int J Food Microbiol. 2015 Jun 16;203:35-40. doi: 10.1016/j.ijfoodmicro.2015.03.007. Epub 2015 Mar 7. PMID: 25777679; PMCID: PMC4587664. |
| Ocvirk S, Sava IG, Lengfelder I, Lagkouvardos I, Steck N, Roh JH, Tchaptchet S, Bao Y, Hansen JJ, Huebner J, Carroll IM, Murray BE, Sartor RB, Haller D. Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels. PLoS Pathog. 2015 Jun 12;11(6):e1004911. doi: 10.1371/journal.ppat.1004911. PMID: 26067254; PMCID: PMC4466351. |
| Rodgers-Vieira EA, Zhang Z, Adrion AC, Gold A, Aitken MD. Identification of anthraquinone-degrading bacteria in soil contaminated with polycyclic aromatic hydrocarbons. Appl Environ Microbiol. 2015 Jun;81(11):3775-81. doi: 10.1128/AEM.00033-15. Epub 2015 Mar 27. PMID: 25819957; PMCID: PMC4421061. |
| Dellon ES, Rusin S, Gebhart JH, Covey S, Higgins LL, Beitia R, Speck O, Woodward K, Woosley JT, Shaheen NJ. Utility of a Noninvasive Serum Biomarker Panel for Diagnosis and Monitoring of Eosinophilic Esophagitis: A Prospective Study. Am J Gastroenterol. 2015 Jun;110(6):821-7. doi: 10.1038/ajg.2015.57. Epub 2015 Mar 17. PMID: 25781367; PMCID: PMC4578703. |
| Keys JR, Zhou S, Anderson JA, Eron JJ Jr, Rackoff LA, Jabara C, Swanstrom R. Primer ID Informs Next-Generation Sequencing Platforms and Reveals Preexisting Drug Resistance Mutations in the HIV-1 Reverse Transcriptase Coding Domain. AIDS Res Hum Retroviruses. 2015 Jun;31(6):658-68. doi: 10.1089/AID.2014.0031. Epub 2015 Apr 2. PMID: 25748056; PMCID: PMC4458739. |
| Ananthakrishnan AN, Kwon J, Raffals L, Sands B, Stenson WF, McGovern D, Kwon JH, Rheaume RL, Sandler RS. Variation in treatment of patients with inflammatory bowel diseases at major referral centers in the United States. Clin Gastroenterol Hepatol. 2015 Jun;13(6):1197-200. doi: 10.1016/j.cgh.2014.11.020. Epub 2014 Nov 21. PMID: 25460565; PMCID: PMC4440845. |
| Zhao N, Chen J, Carroll IM, Ringel-Kulka T, Epstein MP, Zhou H, Zhou JJ, Ringel Y, Li H, Wu MC. Testing in Microbiome-Profiling Studies with MiRKAT, the Microbiome Regression-Based Kernel Association Test. Am J Hum Genet. 2015 May 7;96(5):797-807. doi: 10.1016/j.ajhg.2015.04.003. PMID: 25957468; PMCID: PMC4570290. |
| Hathaway CK, Gasim AM, Grant R, Chang AS, Kim HS, Madden VJ, Bagnell CR Jr, Jennette JC, Smithies O, Kakoki M. Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice. Proc Natl Acad Sci U S A. 2015 May 5;112(18):5815-20. doi: 10.1073/pnas.1504777112. Epub 2015 Apr 20. PMID: 25902541; PMCID: PMC4426439. |
| Mishima Y, Liu B, Hansen JJ, Sartor RB. Resident bacteria-stimulated IL-10-secreting B cells ameliorate T cell-mediated colitis by inducing Tr-1 cells that require IL-27-signaling. Cell Mol Gastroenterol Hepatol. 2015 May 1;1(3):295-310. doi: 10.1016/j.jcmgh.2015.01.002. PMID: 26034781; PMCID: PMC4448782. |
| Shen X, Xi G, Wai C, Clemmons DR. The coordinate cellular response to insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-2 (IGFBP-2) is regulated through vimentin binding to receptor tyrosine phosphatase β (RPTPβ). J Biol Chem. 2015 May 1;290(18):11578-90. doi: 10.1074/jbc.M114.620237. Epub 2015 Mar 18. PMID: 25787077; PMCID: PMC4416861. |
| Jones PD, Kappelman MD, Martin CF, Chen W, Sandler RS, Long MD. Exercise decreases risk of future active disease in patients with inflammatory bowel disease in remission. Inflamm Bowel Dis. 2015 May;21(5):1063-71. doi: 10.1097/MIB.0000000000000333. PMID: 25723616; PMCID: PMC4402239. |
| Zhao C, Qiao C, Tang RH, Jiang J, Li J, Martin CB, Bulaklak K, Li J, Wang DW, Xiao X. Overcoming Insulin Insufficiency by Forced Follistatin Expression in β-cells of db/db Mice. Mol Ther. 2015 May;23(5):866-874. doi: 10.1038/mt.2015.29. Epub 2015 Feb 13. PMID: 25676679; PMCID: PMC4427879. |
| Murphy CC, Lewis CL, Golin CE, Sandler RS. Underuse of surveillance colonoscopy in patients at increased risk of colorectal cancer. Am J Gastroenterol. 2015 May;110(5):633-41. doi: 10.1038/ajg.2014.344. Epub 2014 Nov 11. PMID: 25384901; PMCID: PMC4422764. |
| Jensen ET, Kappelman MD, Martin CF, Dellon ES. Health-care utilization, costs, and the burden of disease related to eosinophilic esophagitis in the United States. Am J Gastroenterol. 2015 May;110(5):626-32. doi: 10.1038/ajg.2014.316. Epub 2014 Sep 30. PMID: 25267327; PMCID: PMC4590991. |
| Gonzalez LM, Fogle CA, Baker WT, Hughes FE, Law JM, Motsinger-Reif AA, Blikslager AT. Operative factors associated with short-term outcome in horses with large colon volvulus: 47 cases from 2006 to 2013. Equine Vet J. 2015 May;47(3):279-84. doi: 10.1111/evj.12273. Epub 2014 May 29. PMID: 24735170; PMCID: PMC4198525. |
| Steinbach EC, Gipson GR, Sheikh SZ. Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+ CD45RB high T Cells into Immunodeficient Mice. J Vis Exp. 2015 Apr 21;(98):52533. doi: 10.3791/52533. PMID: 25938395; PMCID: PMC4541583. |
| Hathaway CK, Grant R, Hagaman JR, Hiller S, Li F, Xu L, Chang AS, Madden VJ, Bagnell CR, Rojas M, Kim HS, Wu B, Zhou B, Smithies O, Kakoki M. Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5141-6. doi: 10.1073/pnas.1504557112. Epub 2015 Apr 6. PMID: 25848038; PMCID: PMC4413291. |
| Utturkar SM, Klingeman DM, Bruno-Barcena JM, Chinn MS, Grunden AM, Köpke M, Brown SD. Sequence data for Clostridium autoethanogenum using three generations of sequencing technologies. Sci Data. 2015 Apr 14;2:150014. doi: 10.1038/sdata.2015.14. PMID: 25977818; PMCID: PMC4409012. |
| Minchin JE, Dahlman I, Harvey CJ, Mejhert N, Singh MK, Epstein JA, Arner P, Torres-Vázquez J, Rawls JF. Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4363-8. doi: 10.1073/pnas.1416412112. Epub 2015 Mar 23. PMID: 25831505; PMCID: PMC4394244. |
| Gonzalez LM, Kinnin LA, Blikslager AT. Characterization of discrete equine intestinal epithelial cell lineages. Am J Vet Res. 2015 Apr;76(4):358-66. doi: 10.2460/ajvr.76.4.358. PMID: 25815577; PMCID: PMC4517574. |
| Borrás T, Smith MH, Buie LK. A Novel Mgp-Cre Knock-In Mouse Reveals an Anticalcification/Antistiffness Candidate Gene in the Trabecular Meshwork and Peripapillary Scleral Region. Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2203-14. doi: 10.1167/iovs.15-16460. PMID: 25711639; PMCID: PMC4406033. |
| Dellon ES, Erichsen R, Baron JA, Shaheen NJ, Vyberg M, Sorensen HT, Pedersen L. The increasing incidence and prevalence of eosinophilic oesophagitis outpaces changes in endoscopic and biopsy practice: national population-based estimates from Denmark. Aliment Pharmacol Ther. 2015 Apr;41(7):662-70. doi: 10.1111/apt.13129. Epub 2015 Feb 12. PMID: 25684441; PMCID: PMC4504237. |
| Goeser L, Fan TJ, Tchaptchet S, Stasulli N, Goldman WE, Sartor RB, Hansen JJ. Small heat-shock proteins, IbpAB, protect non-pathogenic Escherichia coli from killing by macrophage-derived reactive oxygen species. PLoS One. 2015 Mar 23;10(3):e0120249. doi: 10.1371/journal.pone.0120249. PMID: 25798870; PMCID: PMC4370416. |
| Sivaraman V, Pechous RD, Stasulli NM, Eichelberger KR, Miao EA, Goldman WE. Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. PLoS Pathog. 2015 Mar 17;11(3):e1004688. doi: 10.1371/journal.ppat.1004688. Erratum in: PLoS Pathog. 2015 May;11(5):e1004921. PMID: 25781467; PMCID: PMC4363893. |
| Ritchie LE, Sturino JM, Carroll RJ, Rooney LW, Azcarate-Peril MA, Turner ND. Polyphenol-rich sorghum brans alter colon microbiota and impact species diversity and species richness after multiple bouts of dextran sodium sulfate- induced colitis. FEMS Microbiol Ecol. 2015 Mar;91(3):fiv008. doi: 10.1093/femsec/fiv008. Epub 2015 Jan 14. PMID: 25764457; PMCID: PMC4573659. |
| Gracz AD, Williamson IA, Roche KC, Johnston MJ, Wang F, Wang Y, Attayek PJ, Balowski J, Liu XF, Laurenza RJ, Gaynor LT, Sims CE, Galanko JA, Li L, Allbritton NL, Magness ST. A high-throughput platform for stem cell niche co- cultures and downstream gene expression analysis. Nat Cell Biol. 2015 Mar;17(3):340-9. doi: 10.1038/ncb3104. Epub 2015 Feb 9. PMID: 25664616; PMCID: PMC4405128. |
| Matsuki K, Hathaway CK, Chang AS, Smithies O, Kakoki M. Transforming growth factor beta1 and aldosterone. Curr Opin Nephrol Hypertens. 2015 Mar;24(2):139-44. doi: 10.1097/MNH.0000000000000100. PMID: 25587902; PMCID: PMC4838512. |
| Keku TO, Dulal S, Deveaux A, Jovov B, Han X. The gastrointestinal microbiota and colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 1;308(5):G351-63. doi: 10.1152/ajpgi.00360.2012. Epub 2014 Dec 24. PMID: 25540232; PMCID: PMC4346754. |
| Figueiredo JC, Crockett SD, Snover DC, Morris CB, McKeown-Eyssen G, Sandler RS, Ahnen DJ, Robertson DJ, Burke CA, Bresalier RS, Church JM, Church TR, Baron JA. Smoking-associated risks of conventional adenomas and serrated polyps in the colorectum. Cancer Causes Control. 2015 Mar;26(3):377-86. doi: 10.1007/s10552-014-0513-0. Epub 2014 Dec 24. PMID: 25537738; PMCID: PMC4331601. |
| Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. FASEB J. 2015 Mar;29(3):1043-55. doi: 10.1096/fj.14-259515. Epub 2014 Dec 2. PMID: 25466902; PMCID: PMC4422368. |
| Dellon ES, Speck O, Woodward K, Covey S, Rusin S, Shaheen NJ, Woosley JT. Distribution and variability of esophageal eosinophilia in patients undergoing upper endoscopy. Mod Pathol. 2015 Mar;28(3):383-90. doi: 10.1038/modpathol.2014.110. Epub 2014 Sep 12. PMID: 25216228; PMCID: PMC4344855. |
| Wolf WA, Cotton CC, Green DJ, Hughes JT, Woosley JT, Shaheen NJ, Dellon ES. Predictors of response to steroid therapy for eosinophilic esophagitis and treatment of steroid-refractory patients. Clin Gastroenterol Hepatol. 2015 Mar;13(3):452-8. doi: 10.1016/j.cgh.2014.07.034. Epub 2014 Jul 30. Erratum in: Clin Gastroenterol Hepatol. 2015 May;13(5):1031. Dosage error in article text. PMID: 25086190; PMCID: PMC4312270. |
| Piccini C, García-Alonso J. Bacterial diversity patterns of the intertidal biofilm in urban beaches of Río de la Plata. Mar Pollut Bull. 2015 Feb 28;91(2):476-82. doi: 10.1016/j.marpolbul.2014.08.039. Epub 2014 Sep 22. PMID: 25249253. |
| Pechous RD, Broberg CA, Stasulli NM, Miller VL, Goldman WE. In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation. mBio. 2015 Feb 17;6(1):e02302-14. doi: 10.1128/mBio.02302-14. PMID: 25691593; PMCID: PMC4337571. |
| Kubinak JL, Petersen C, Stephens WZ, Soto R, Bake E, O'Connell RM, Round JL. MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health. Cell Host Microbe. 2015 Feb 11;17(2):153-63. doi: 10.1016/j.chom.2014.12.009. Epub 2015 Jan 22. PMID: 25620548; PMCID: PMC4451207. |
| Thompson AL, Monteagudo-Mera A, Cadenas MB, Lampl ML, Azcarate-Peril MA. Milk- and solid-feeding practices and daycare attendance are associated with differences in bacterial diversity, predominant communities, and metabolic and immune function of the infant gut microbiome. Front Cell Infect Microbiol. 2015 Feb 5;5:3. doi: 10.3389/fcimb.2015.00003. PMID: 25705611; PMCID: PMC4318912. |
| Call EK, Goh YJ, Selle K, Klaenhammer TR, O'Flaherty S. Sortase-deficient lactobacilli: effect on immunomodulation and gut retention. Microbiology (Reading). 2015 Feb;161(Pt 2):311-321. doi: 10.1099/mic.0.000007. Epub 2014 Dec 12. PMID: 25500495; PMCID: PMC4811640. |
| Gonzalez LM, Moeser AJ, Blikslager AT. Animal models of ischemia- reperfusion-induced intestinal injury: progress and promise for translational research. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 15;308(2):G63-75. doi: 10.1152/ajpgi.00112.2013. Epub 2014 Nov 20. PMID: 25414098; PMCID: PMC4297854. |
| Andres SF, Santoro MA, Mah AT, Keku JA, Bortvedt AE, Blue RE, Lund PK. Deletion of intestinal epithelial insulin receptor attenuates high-fat diet- induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 15;308(2):G100-11. doi: 10.1152/ajpgi.00287.2014. Epub 2014 Nov 13. PMID: 25394660; PMCID: PMC4297856. |
| Ringel Y, Maharshak N, Ringel-Kulka T, Wolber EA, Sartor RB, Carroll IM. High throughput sequencing reveals distinct microbial populations within the mucosal and luminal niches in healthy individuals. Gut Microbes. 2015;6(3):173-81. doi: 10.1080/19490976.2015.1044711. PMID: 25915459; PMCID: PMC4615648. |
| Allali I, Delgado S, Marron PI, Astudillo A, Yeh JJ, Ghazal H, Amzazi S, Keku T, Azcarate-Peril MA. Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain. Gut Microbes. 2015;6(3):161-72. doi: 10.1080/19490976.2015.1039223. PMID: 25875428; PMCID: PMC4615176. |
| Cotton CC, Wolf WA, Pasricha S, Li N, Madanick RD, Spacek MB, Ferrell K, Dellon ES, Shaheen NJ. Recurrent intestinal metaplasia after radiofrequency ablation for Barrett's esophagus: endoscopic findings and anatomic location. Gastrointest Endosc. 2015;81(6):1362-9. doi: 10.1016/j.gie.2014.12.029. Epub 2015 Mar 24. PMID: 25817897; PMCID: PMC4439393. |
| Bruno-Barcena JM, Azcarate-Peril MA. Galacto-oligosaccharides and Colorectal Cancer: Feeding our Intestinal Probiome. J Funct Foods. 2015 Jan;12:92-108. doi: 10.1016/j.jff.2014.10.029. PMID: 25584074; PMCID: PMC4288025. |
| Busch EL, Martin C, DeWalt DA, Sandler RS. Functional health literacy, chemotherapy decisions, and outcomes among a colorectal cancer cohort. Cancer Control. 2015 Jan;22(1):95-101. doi: 10.1177/107327481502200112. PMID: 25504283; PMCID: PMC4578694. |
| Long MD, Cadigan RJ, Cook SF, Haldeman K, Kuczynski K, Sandler RS, Martin CF, Chen W, Kappelman MD. Perceptions of patients with inflammatory bowel diseases on biobanking. Inflamm Bowel Dis. 2015 Jan;21(1):132-8. doi: 10.1097/MIB.0000000000000263. PMID: 25489961; PMCID: PMC4573563. |
| Murphy CC, Martin CF, Sandler RS. Racial differences in obesity measures and risk of colorectal adenomas in a large screening population. Nutr Cancer. 2015;67(1):98-104. doi: 10.1080/01635581.2015.976316. Epub 2014 Nov 25. PMID: 25425186; PMCID: PMC4281505. |
| Morgan AP, Crowley JJ, Nonneman RJ, Quackenbush CR, Miller CN, Ryan AK, Bogue MA, Paredes SH, Yourstone S, Carroll IM, Kawula TH, Bower MA, Sartor RB, Sullivan PF. The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse. PLoS One. 2014 Dec 15;9(12):e115225. doi: 10.1371/journal.pone.0115225. PMID: 25506936; PMCID: PMC4266663. |
| Donohoe DR, Holley D, Collins LB, Montgomery SA, Whitmore AC, Hillhouse A, Curry KP, Renner SW, Greenwalt A, Ryan EP, Godfrey V, Heise MT, Threadgill DS, Han A, Swenberg JA, Threadgill DW, Bultman SJ. A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner. Cancer Discov. 2014 Dec;4(12):1387-97. doi: 10.1158/2159-8290.CD-14-0501. Epub 2014 Sep 29. PMID: 25266735; PMCID: PMC4258155. |
| Dellon ES, Speck O, Woodward K, Covey S, Rusin S, Gebhart JH, Chen X, Woosley JT, Shaheen NJ. Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study. Clin Gastroenterol Hepatol. 2014 Dec;12(12):2015-22. doi: 10.1016/j.cgh.2014.06.019. Epub 2014 Jun 30. PMID: 24993367; PMCID: PMC4252508. |
| Goh YJ, Klaenhammer TR. Insights into glycogen metabolism in Lactobacillus acidophilus: impact on carbohydrate metabolism, stress tolerance and gut retention. Microb Cell Fact. 2014 Nov 20;13:94. doi: 10.1186/s12934-014-0094-3. PMID: 25410006; PMCID: PMC4243779. |
| Perez-Chanona E, Mühlbauer M, Jobin C. The microbiota protects against ischemia/reperfusion-induced intestinal injury through nucleotide-binding oligomerization domain-containing protein 2 (NOD2) signaling. Am J Pathol. 2014 Nov;184(11):2965-75. doi: 10.1016/j.ajpath.2014.07.014. Epub 2014 Sep 6. PMID: 25204845; PMCID: PMC4215024. |
| Crockett SD, Mott LA, Barry EL, Figueiredo JC, Burke CA, Baxter GJ, Sandler RS, Baron JA. C-reactive protein and risk of colorectal adenomas or serrated polyps: a prospective study. Cancer Prev Res (Phila). 2014 Nov;7(11):1122-7. doi: 10.1158/1940-6207.CAPR-14-0167. Epub 2014 Aug 21. PMID: 25145487; PMCID: PMC4221539. |
| Sundaram S, Freemerman AJ, Galanko JA, McNaughton KK, Bendt KM, Darr DB, Troester MA, Makowski L. Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice. PLoS One. 2014 Oct 29;9(10):e111394. doi: 10.1371/journal.pone.0111394. PMID: 25354395; PMCID: PMC4213021. |
| Schuck RN, Zha W, Edin ML, Gruzdev A, Vendrov KC, Miller TM, Xu Z, Lih FB, DeGraff LM, Tomer KB, Jones HM, Makowski L, Huang L, Poloyac SM, Zeldin DC, Lee CR. The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease. PLoS One. 2014 Oct 13;9(10):e110162. doi: 10.1371/journal.pone.0110162. PMID: 25310404; PMCID: PMC4195706. |
| Zha W, Edin ML, Vendrov KC, Schuck RN, Lih FB, Jat JL, Bradbury JA, DeGraff LM, Hua K, Tomer KB, Falck JR, Zeldin DC, Lee CR. Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity. J Lipid Res. 2014 Oct;55(10):2124-36. doi: 10.1194/jlr.M053199. Epub 2014 Aug 11. PMID: 25114171; PMCID: PMC4174005. |
| Jabara CB, Hu F, Mollan KR, Williford SE, Menezes P, Yang Y, Eron JJ, Fried MW, Hudgens MG, Jones CD, Swanstrom R, Lemon SM. Hepatitis C Virus (HCV) NS3 sequence diversity and antiviral resistance-associated variant frequency in HCV/HIV coinfection. Antimicrob Agents Chemother. 2014 Oct;58(10):6079-92. doi: 10.1128/AAC.03466-14. Epub 2014 Aug 4. PMID: 25092699; PMCID: PMC4187920. |
| Santoro MA, Andres SF, Galanko JA, Sandler RS, Keku TO, Lund PK. Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):2093-100. doi: 10.1158/1055-9965.EPI-14-0177. Epub 2014 Jul 13. PMID: 25017244; PMCID: PMC4201381. |
| Sun X, Jobin C. Nucleotide-binding oligomerization domain-containing protein 2 controls host response to Campylobacter jejuni in Il10-/- mice. J Infect Dis. 2014 Oct 1;210(7):1145-54. doi: 10.1093/infdis/jiu148. Epub 2014 Mar 11. PMID: 24620022; PMCID: PMC4168300. |
| Thrift AP, Risch HA, Onstad L, Shaheen NJ, Casson AG, Bernstein L, Corley DA, Levine DM, Chow WH, Reid BJ, Romero Y, Hardie LJ, Liu G, Wu AH, Bird NC, Gammon MD, Ye W, Whiteman DC, Vaughan TL. Risk of esophageal adenocarcinoma decreases with height, based on consortium analysis and confirmed by Mendelian randomization. Clin Gastroenterol Hepatol. 2014 Oct;12(10):1667-76.e1. doi: 10.1016/j.cgh.2014.01.039. Epub 2014 Feb 12. PMID: 24530603; PMCID: PMC4130803. |
| Oh JZ, Ravindran R, Chassaing B, Carvalho FA, Maddur MS, Bower M, Hakimpour P, Gill KP, Nakaya HI, Yarovinsky F, Sartor RB, Gewirtz AT, Pulendran B. TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination. Immunity. 2014 Sep 18;41(3):478-492. doi: 10.1016/j.immuni.2014.08.009. Epub 2014 Sep 11. PMID: 25220212; PMCID: PMC4169736. |
| Saini Y, Dang H, Livraghi-Butrico A, Kelly EJ, Jones LC, O'Neal WK, Boucher RC. Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration. BMC Genomics. 2014 Sep 10;15(1):726. doi: 10.1186/1471-2164-15-726. PMID: 25204199; PMCID: PMC4247008. |
| Arthur JC, Gharaibeh RZ, Mühlbauer M, Perez-Chanona E, Uronis JM, McCafferty J, Fodor AA, Jobin C. Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer. Nat Commun. 2014 Sep 3;5:4724. doi: 10.1038/ncomms5724. PMID: 25182170; PMCID: PMC4155410. |
| Camp JG, Frank CL, Lickwar CR, Guturu H, Rube T, Wenger AM, Chen J, Bejerano G, Crawford GE, Rawls JF. Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape. Genome Res. 2014 Sep;24(9):1504-16. doi: 10.1101/gr.165845.113. Epub 2014 Jun 24. PMID: 24963153; PMCID: PMC4158762. |
| Miller CA, Corbin KD, da Costa KA, Zhang S, Zhao X, Galanko JA, Blevins T, Bennett BJ, O'Connor A, Zeisel SH. Effect of egg ingestion on trimethylamine-N- oxide production in humans: a randomized, controlled, dose-response study. Am J Clin Nutr. 2014 Sep;100(3):778-86. doi: 10.3945/ajcn.114.087692. Epub 2014 Jun 18. PMID: 24944063; PMCID: PMC4135488. |
| Mah AT, Van Landeghem L, Gavin HE, Magness ST, Lund PK. Impact of diet- induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1. Endocrinology. 2014 Sep;155(9):3302-14. doi: 10.1210/en.2014-1112. Epub 2014 Jun 10. PMID: 24914941; PMCID: PMC4138564. |
| Kupfer SS, Skol AD, Hong E, Ludvik A, Kittles RA, Keku TO, Sandler RS, Ellis NA. Shared and independent colorectal cancer risk alleles in TGFβ-related genes in African and European Americans. Carcinogenesis. 2014 Sep;35(9):2025-30. doi: 10.1093/carcin/bgu088. Epub 2014 Apr 21. PMID: 24753543; PMCID: PMC4146413. |
| Gracz AD, Magness ST. Defining hierarchies of stemness in the intestine: evidence from biomarkers and regulatory pathways. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 1;307(3):G260-73. doi: 10.1152/ajpgi.00066.2014. Epub 2014 Jun 12. PMID: 24924746; PMCID: PMC4121637. |
| Kappelman MD, Long MD, Martin C, DeWalt DA, Kinneer PM, Chen W, Lewis JD, Sandler RS. Evaluation of the patient-reported outcomes measurement information system in a large cohort of patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014 Aug;12(8):1315-23.e2. doi: 10.1016/j.cgh.2013.10.019. Epub 2013 Oct 29. PMID: 24183956; PMCID: PMC4361943. |
| Sundaram S, Le TL, Essaid L, Freemerman AJ, Huang MJ, Galanko JA, McNaughton KK, Bendt KM, Darr DB, Troester MA, Makowski L. Weight Loss Reversed Obesity-Induced HGF/c-Met Pathway and Basal-Like Breast Cancer Progression. Front Oncol. 2014 Jul 8;4:175. doi: 10.3389/fonc.2014.00175. PMID: 25072025; PMCID: PMC4085881. |
| Sepúlveda VE, Williams CL, Goldman WE. Comparison of phylogenetically distinct Histoplasma strains reveals evolutionarily divergent virulence strategies. mBio. 2014 Jul 1;5(4):e01376-14. doi: 10.1128/mBio.01376-14. PMID: 24987093; PMCID: PMC4161242. |
| Herfarth HH, Martin CF, Sandler RS, Kappelman MD, Long MD. Prevalence of a gluten-free diet and improvement of clinical symptoms in patients with inflammatory bowel diseases. Inflamm Bowel Dis. 2014 Jul;20(7):1194-7. doi: 10.1097/MIB.0000000000000077. PMID: 24865778; PMCID: PMC4331053. |
| Ringel-Kulka T, Goldsmith JR, Carroll IM, Barros SP, Palsson O, Jobin C, Ringel Y. Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study. Aliment Pharmacol Ther. 2014 Jul;40(2):200-7. doi: 10.1111/apt.12800. Epub 2014 May 22. PMID: 24853043; PMCID: PMC4613798. |
| da Costa KA, Corbin KD, Niculescu MD, Galanko JA, Zeisel SH. Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups. FASEB J. 2014 Jul;28(7):2970-8. doi: 10.1096/fj.14-249557. Epub 2014 Mar 26. PMID: 24671709; PMCID: PMC4062831. |
| Kanther M, Tomkovich S, Xiaolun S, Grosser MR, Koo J, Flynn EJ 3rd, Jobin C, Rawls JF. Commensal microbiota stimulate systemic neutrophil migration through induction of serum amyloid A. Cell Microbiol. 2014 Jul;16(7):1053-67. doi: 10.1111/cmi.12257. Epub 2014 Jan 24. PMID: 24373309; PMCID: PMC4364439. |
| Carethers JM, Murali B, Yang B, Doctolero RT, Tajima A, Basa R, Smith EJ, Lee M, Janke R, Ngo T, Tejada R, Ji M, Kinseth M, Cabrera BL, Miyai K, Keku TO, Martin CF, Galanko JA, Sandler RS, McGuire KL. Influence of race on microsatellite instability and CD8+ T cell infiltration in colon cancer. PLoS One. 2014 Jun 23;9(6):e100461. doi: 10.1371/journal.pone.0100461. Erratum in: PLoS One. 2014;9(7):e103699. PMID: 24956473; PMCID: PMC4067325. |
| Ibarbalz FM, Pérez MV, Figuerola EL, Erijman L. The bias associated with amplicon sequencing does not affect the quantitative assessment of bacterial community dynamics. PLoS One. 2014 Jun 12;9(6):e99722. doi: 10.1371/journal.pone.0099722. PMID: 24923665; PMCID: PMC4055690. |
| Lindenstrauss AG, Ehrmann MA, Behr J, Landstorfer R, Haller D, Sartor RB, Vogel RF. Transcriptome analysis of Enterococcus faecalis toward its adaption to surviving in the mouse intestinal tract. Arch Microbiol. 2014 Jun;196(6):423-33. doi: 10.1007/s00203-014-0982-2. Epub 2014 Apr 4. PMID: 24700373. |
| Eun CS, Mishima Y, Wohlgemuth S, Liu B, Bower M, Carroll IM, Sartor RB. Induction of bacterial antigen-specific colitis by a simplified human microbiota consortium in gnotobiotic interleukin-10-/- mice. Infect Immun. 2014 Jun;82(6):2239-46. doi: 10.1128/IAI.01513-13. Epub 2014 Mar 18. PMID: 24643531; PMCID: PMC4019192. |
| Shanahan MT, Carroll IM, Grossniklaus E, White A, von Furstenberg RJ, Barner R, Fodor AA, Henning SJ, Sartor RB, Gulati AS. Mouse Paneth cell antimicrobial function is independent of Nod2. Gut. 2014 Jun;63(6):903-10. doi: 10.1136/gutjnl-2012-304190. Epub 2013 Mar 19. PMID: 23512834; PMCID: PMC3844066. |
| Wang Y, Ahmad AA, Sims CE, Magness ST, Allbritton NL. In vitro generation of colonic epithelium from primary cells guided by microstructures. Lab Chip. 2014 May 7;14(9):1622-31. doi: 10.1039/c3lc51353j. Epub 2014 Mar 20. PMID: 24647645; PMCID: PMC4037563. |
| Proctor A, Herrera-Loeza SG, Wang Q, Lawrence DS, Yeh JJ, Allbritton NL. Measurement of protein kinase B activity in single primary human pancreatic cancer cells. Anal Chem. 2014 May 6;86(9):4573-80. doi: 10.1021/ac500616q. Epub 2014 Apr 18. PMID: 24716819; PMCID: PMC4018172. |
| Dulal S, Keku TO. Gut microbiome and colorectal adenomas. Cancer J. 2014 May-Jun;20(3):225-31. doi: 10.1097/PPO.0000000000000050. PMID: 24855012; PMCID: PMC4589167. |
| Deshmukh HS, Liu Y, Menkiti OR, Mei J, Dai N, O'Leary CE, Oliver PM, Kolls JK, Weiser JN, Worthen GS. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat Med. 2014 May;20(5):524-30. doi: 10.1038/nm.3542. Epub 2014 Apr 20. PMID: 24747744; PMCID: PMC4016187. |
| Hill TL, Lascelles BD, Law JM, Blikslager AT. The effect of tramadol and indomethacin coadministration on gastric barrier function in dogs. J Vet Intern Med. 2014 May-Jun;28(3):793-8. doi: 10.1111/jvim.12345. Epub 2014 Mar 31. PMID: 24684670; PMCID: PMC4497006. |
| Pibiri F, Kittles RA, Sandler RS, Keku TO, Kupfer SS, Xicola RM, Llor X, Ellis NA. Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans. Cancer Causes Control. 2014 May;25(5):561-70. doi: 10.1007/s10552-014-0361-y. Epub 2014 Feb 23. PMID: 24562971; PMCID: PMC3978221. |
| Altamirano J, Miquel R, Katoonizadeh A, Abraldes JG, Duarte-Rojo A, Louvet A, Augustin S, Mookerjee RP, Michelena J, Smyrk TC, Buob D, Leteurtre E, Rincón D, Ruiz P, García-Pagán JC, Guerrero-Marquez C, Jones PD, Barritt AS 4th, Arroyo V, Bruguera M, Bañares R, Ginès P, Caballería J, Roskams T, Nevens F, Jalan R, Mathurin P, Shah VH, Bataller R. A histologic scoring system for prognosis of patients with alcoholic hepatitis. Gastroenterology. 2014 May;146(5):1231-9.e1-6. doi: 10.1053/j.gastro.2014.01.018. Epub 2014 Jan 15. PMID: 24440674; PMCID: PMC3992184. |
| Harley IT, Stankiewicz TE, Giles DA, Softic S, Flick LM, Cappelletti M, Sheridan R, Xanthakos SA, Steinbrecher KA, Sartor RB, Kohli R, Karp CL, Divanovic S. IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. Hepatology. 2014 May;59(5):1830-9. doi: 10.1002/hep.26746. Epub 2014 Mar 27. PMID: 24115079; PMCID: PMC3975735. |
| Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE. Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis. J Immunol. 2014 Apr 15;192(8):3958-68. doi: 10.4049/jimmunol.1301533. Epub 2014 Mar 14. PMID: 24634494; PMCID: PMC3992276. |
| Gach PC, Attayek PJ, Whittlesey RL, Yeh JJ, Allbritton NL. Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma. Biosens Bioelectron. 2014 Apr 15;54:476-83. doi: 10.1016/j.bios.2013.11.019. Epub 2013 Nov 18. PMID: 24316450; PMCID: PMC3947965. |
| Nugent JL, McCoy AN, Addamo CJ, Jia W, Sandler RS, Keku TO. Altered tissue metabolites correlate with microbial dysbiosis in colorectal adenomas. J Proteome Res. 2014 Apr 4;13(4):1921-9. doi: 10.1021/pr4009783. Epub 2014 Mar 21. PMID: 24601673; PMCID: PMC3993967. |
| Steck SE, Butler LM, Keku T, Antwi S, Galanko J, Sandler RS, Hu JJ. Nucleotide excision repair gene polymorphisms, meat intake and colon cancer risk. Mutat Res. 2014 Apr;762:24-31. doi: 10.1016/j.mrfmmm.2014.02.004. Epub 2014 Mar 7. PMID: 24607854; PMCID: PMC4056032. |
| Dellon ES, Jensen ET, Martin CF, Shaheen NJ, Kappelman MD. Prevalence of eosinophilic esophagitis in the United States. Clin Gastroenterol Hepatol. 2014 Apr;12(4):589-96.e1. doi: 10.1016/j.cgh.2013.09.008. Epub 2013 Sep 11. PMID: 24035773; PMCID: PMC3952040. |
| Freemerman AJ, Johnson AR, Sacks GN, Milner JJ, Kirk EL, Troester MA, Macintyre AN, Goraksha-Hicks P, Rathmell JC, Makowski L. Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. J Biol Chem. 2014 Mar 14;289(11):7884-96. doi: 10.1074/jbc.M113.522037. Epub 2014 Feb 3. PMID: 24492615; PMCID: PMC3953299. |
| Shanahan MT, Carroll IM, Gulati AS. Critical design aspects involved in the study of Paneth cells and the intestinal microbiota. Gut Microbes. 2014 Mar- Apr;5(2):208-14. doi: 10.4161/gmic.27466. Epub 2013 Dec 20. PMID: 24637592; PMCID: PMC4063846. |
| Randell RL, Long MD, Cook SF, Wrennall CE, Chen W, Martin CF, Anton K, Sandler RS, Kappelman MD. Validation of an internet-based cohort of inflammatory bowel disease (CCFA partners). Inflamm Bowel Dis. 2014 Mar;20(3):541-4. doi: 10.1097/01.MIB.0000441348.32570.34. PMID: 24451221; PMCID: PMC4112538. |
| von Furstenberg RJ, Buczacki SJ, Smith BJ, Seiler KM, Winton DJ, Henning SJ. Side population sorting separates subfractions of cycling and non-cycling intestinal stem cells. Stem Cell Res. 2014 Mar;12(2):364-75. doi: 10.1016/j.scr.2013.10.012. Epub 2013 Nov 9. PMID: 24365601; PMCID: PMC3951668. |
| Torphy RJ, Tignanelli CJ, Kamande JW, Moffitt RA, Herrera Loeza SG, Soper SA, Yeh JJ. Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma. PLoS One. 2014 Feb 19;9(2):e89474. doi: 10.1371/journal.pone.0089474. PMID: 24586805; PMCID: PMC3929698. |
| Kobayashi T, Steinbach EC, Russo SM, Matsuoka K, Nochi T, Maharshak N, Borst LB, Hostager B, Garcia-Martinez JV, Rothman PB, Kashiwada M, Sheikh SZ, Murray PJ, Plevy SE. NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis. J Immunol. 2014 Feb 15;192(4):1918-27. doi: 10.4049/jimmunol.1301819. Epub 2014 Jan 17. PMID: 24442434; PMCID: PMC3948213. |
| Camargo MC, Koriyama C, Matsuo K, Kim WH, Herrera-Goepfert R, Liao LM; Eurgast-EPIC Group, Yu J, Carrasquilla G, Sung JJ, Alvarado-Cabrero I, Lissowska J, Meneses-Gonzalez F, Yatabe Y, Ding T, Hu N, Taylor PR, Morgan DR, Gulley ML, Torres J, Akiba S, Rabkin CS. Case-case comparison of smoking and alcohol risk associations with Epstein-Barr virus-positive gastric cancer. Int J Cancer. 2014 Feb 15;134(4):948-53. doi: 10.1002/ijc.28402. Epub 2013 Aug 28. PMID: 23904115; PMCID: PMC3961829. |
| Wasan SK, Calderwood AH, Long MD, Kappelman MD, Sandler RS, Farraye FA. Immunization rates and vaccine beliefs among patients with inflammatory bowel disease: an opportunity for improvement. Inflamm Bowel Dis. 2014 Feb;20(2):246-50. doi: 10.1097/01.MIB.0000437737.68841.87. PMID: 24374881; PMCID: PMC4393851. |
| Ding S, Blue RE, Morgan DR, Lund PK. Comparison of multiple enzyme activatable near-infrared fluorescent molecular probes for detection and quantification of inflammation in murine colitis models. Inflamm Bowel Dis. 2014 Feb;20(2):363-77. doi: 10.1097/01.MIB.0000440612.98950.79. PMID: 24374874; PMCID: PMC4618379. |
| Long MD, Hutfless S, Kappelman MD, Khalili H, Kaplan GG, Bernstein CN, Colombel JF, Gower-Rousseau C, Herrinton L, Velayos F, Loftus EV Jr, Nguyen GC, Ananthakrishnan AN, Sonnenberg A, Chan A, Sandler RS, Atreja A, Shah SA, Rothman KJ, Leleiko NS, Bright R, Boffetta P, Myers KD, Sands BE. Challenges in designing a national surveillance program for inflammatory bowel disease in the United States. Inflamm Bowel Dis. 2014 Feb;20(2):398-415. doi: 10.1097/01.MIB.0000435441.30107.8b. PMID: 24280882; PMCID: PMC4610029. |
| Sofi MH, Gudi R, Karumuthil-Melethil S, Perez N, Johnson BM, Vasu C. pH of drinking water influences the composition of gut microbiome and type 1 diabetes incidence. Diabetes. 2014 Feb;63(2):632-44. doi: 10.2337/db13-0981. Epub 2013 Nov 5. PMID: 24194504; PMCID: PMC3900548. |
| Long MD, Kappelman MD, Martin CF, Chen W, Anton K, Sandler RS. Risk factors for depression in the elderly inflammatory bowel disease population. J Crohns Colitis. 2014 Feb;8(2):113-9. doi: 10.1016/j.crohns.2013.07.002. Epub 2013 Aug 6. PMID: 23932782; PMCID: PMC4589203. |
| Ooi JH, Waddell A, Lin YD, Albert I, Rust LT, Holden V, Cantorna MT. Dominant effects of the diet on the microbiome and the local and systemic immune response in mice. PLoS One. 2014 Jan 29;9(1):e86366. doi: 10.1371/journal.pone.0086366. PMID: 24489720; PMCID: PMC3906035. |
| Tilstra JS, Gaddy DF, Zhao J, Davé SH, Niedernhofer LJ, Plevy SE, Robbins PD. Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death. Sci Rep. 2014 Jan 10;4:3631. doi: 10.1038/srep03631. PMID: 24406986; PMCID: PMC3887388. |
| Dassopoulos T, Dubinsky MC, Bentsen JL, Martin CF, Galanko JA, Seidman EG, Sandler RS, Hanauer SB. Randomised clinical trial: individualised vs. weight- based dosing of azathioprine in Crohn's disease. Aliment Pharmacol Ther. 2014 Jan;39(2):163-75. doi: 10.1111/apt.12555. Epub 2013 Nov 17. PMID: 24237037; PMCID: PMC3918445. |
| Ponnusamy L, Gonzalez A, Van Treuren W, Weiss S, Parobek CM, Juliano JJ, Knight R, Roe RM, Apperson CS, Meshnick SR. Diversity of Rickettsiales in the microbiome of the lone star tick, Amblyomma americanum. Appl Environ Microbiol. 2014 Jan;80(1):354-9. doi: 10.1128/AEM.02987-13. Epub 2013 Oct 25. PMID: 24162580; PMCID: PMC3910995. |
| Qin Y, Hamilton JL, Bird MD, Chen MM, Ramirez L, Zahs A, Kovacs EJ, Makowski L. Adipose inflammation and macrophage infiltration after binge ethanol and burn injury. Alcohol Clin Exp Res. 2014 Jan;38(1):204-13. doi: 10.1111/acer.12210. Epub 2013 Aug 1. PMID: 23909743; PMCID: PMC3823749. |
| He Q, Morillon YM 2nd, Spidale NA, Kroger CJ, Liu B, Sartor RB, Wang B, Tisch R. Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent manner. J Immunol. 2013 Dec 15;191(12):5858-66. doi: 10.4049/jimmunol.1302273. Epub 2013 Nov 6. PMID: 24198282; PMCID: PMC3858497. |
| Andres SF, Simmons JG, Mah AT, Santoro MA, Van Landeghem L, Lund PK. Insulin receptor isoform switching in intestinal stem cells, progenitors, differentiated lineages and tumors: evidence that IR-B limits proliferation. J Cell Sci. 2013 Dec 15;126(Pt 24):5645-56. doi: 10.1242/jcs.132985. Epub 2013 Oct 14. PMID: 24127567; PMCID: PMC3860310. |
| Wang H, Haiman CA, Burnett T, Fortini BK, Kolonel LN, Henderson BE, Signorello LB, Blot WJ, Keku TO, Berndt SI, Newcomb PA, Pande M, Amos CI, West DW, Casey G, Sandler RS, Haile R, Stram DO, Le Marchand L. Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans. Hum Mol Genet. 2013 Dec 15;22(24):5048-55. doi: 10.1093/hmg/ddt337. Epub 2013 Jul 12. PMID: 23851122; PMCID: PMC3836473. |
| Sundaram S, Freemerman AJ, Johnson AR, Milner JJ, McNaughton KK, Galanko JA, Bendt KM, Darr DB, Perou CM, Troester MA, Makowski L. Role of HGF in obesity-associated tumorigenesis: C3(1)-TAg mice as a model for human basal-like breast cancer. Breast Cancer Res Treat. 2013 Dec;142(3):489-503. doi: 10.1007/s10549-013-2741-5. Epub 2013 Nov 12. PMID: 24218051; PMCID: PMC3904507. |
| Dellon ES, Speck O, Woodward K, Gebhart JH, Madanick RD, Levinson S, Fritchie KJ, Woosley JT, Shaheen NJ. Clinical and endoscopic characteristics do not reliably differentiate PPI-responsive esophageal eosinophilia and eosinophilic esophagitis in patients undergoing upper endoscopy: a prospective cohort study. Am J Gastroenterol. 2013 Dec;108(12):1854-60. doi: 10.1038/ajg.2013.363. Epub 2013 Oct 22. PMID: 24145677; PMCID: PMC4574875. |
| Mühlbauer M, Perez-Chanona E, Jobin C. Epithelial cell-specific MyD88 signaling mediates ischemia/reperfusion-induced intestinal injury independent of microbial status. Inflamm Bowel Dis. 2013 Dec;19(13):2857-66. doi: 10.1097/01.MIB.0000435445.96933.37. PMID: 24141713; PMCID: PMC4039295. |
| Sandoval-Espinola WJ, Makwana ST, Chinn MS, Thon MR, Azcárate-Peril MA, Bruno-Bárcena JM. Comparative phenotypic analysis and genome sequence of Clostridium beijerinckii SA-1, an offspring of NCIMB 8052. Microbiology (Reading). 2013 Dec;159(Pt 12):2558-2570. doi: 10.1099/mic.0.069534-0. Epub 2013 Sep 25. PMID: 24068240; PMCID: PMC7336276. |
| Nighot P, Young K, Nighot M, Rawat M, Sung EJ, Maharshak N, Plevy SE, Ma T, Blikslager A. Chloride channel ClC-2 is a key factor in the development of DSS- induced murine colitis. Inflamm Bowel Dis. 2013 Dec;19(13):2867-77. doi: 10.1097/MIB.0b013e3182a82ae9. PMID: 24030525; PMCID: PMC3880115. |
| Gessner RC, Hanson AD, Feingold S, Cashion AT, Corcimaru A, Wu BT, Mullins CR, Aylward SR, Reid LM, Dayton PA. Functional ultrasound imaging for assessment of extracellular matrix scaffolds used for liver organoid formation. Biomaterials. 2013 Dec;34(37):9341-51. doi: 10.1016/j.biomaterials.2013.08.033. Epub 2013 Sep 4. PMID: 24011714; PMCID: PMC4597479. |
| Karmarkar D, Rock KL. Microbiota signalling through MyD88 is necessary for a systemic neutrophilic inflammatory response. Immunology. 2013 Dec;140(4):483-92. doi: 10.1111/imm.12159. PMID: 23909393; PMCID: PMC3839652. |
| Peery AF, Sandler RS, Ahnen DJ, Galanko JA, Holm AN, Shaukat A, Mott LA, Barry EL, Fried DA, Baron JA. Constipation and a low-fiber diet are not associated with diverticulosis. Clin Gastroenterol Hepatol. 2013 Dec;11(12):1622-7. doi: 10.1016/j.cgh.2013.06.033. Epub 2013 Jul 23. PMID: 23891924; PMCID: PMC3840096. |
| Wagner NJ, Lin CP, Borst LB, Miller VL. YaxAB, a Yersinia enterocolitica pore-forming toxin regulated by RovA. Infect Immun. 2013 Nov;81(11):4208-19. doi: 10.1128/IAI.00781-13. Epub 2013 Sep 3. PMID: 24002058; PMCID: PMC3811828. |
| McCafferty J, Mühlbauer M, Gharaibeh RZ, Arthur JC, Perez-Chanona E, Sha W, Jobin C, Fodor AA. Stochastic changes over time and not founder effects drive cage effects in microbial community assembly in a mouse model. ISME J. 2013 Nov;7(11):2116-25. doi: 10.1038/ismej.2013.106. Epub 2013 Jul 4. PMID: 23823492; PMCID: PMC3806260. |
| Fuller MK, Faulk DM, Sundaram N, Mahe MM, Stout KM, von Furstenberg RJ, Smith BJ, McNaughton KK, Shroyer NF, Helmrath MA, Henning SJ. Intestinal stem cells remain viable after prolonged tissue storage. Cell Tissue Res. 2013 Nov;354(2):441-50. doi: 10.1007/s00441-013-1674-y. Epub 2013 Jul 3. PMID: 23820734; PMCID: PMC3812345. |
| Carroll IM, Ringel-Kulka T, Ferrier L, Wu MC, Siddle JP, Bueno L, Ringel Y. Fecal protease activity is associated with compositional alterations in the intestinal microbiota. PLoS One. 2013 Oct 17;8(10):e78017. doi: 10.1371/journal.pone.0078017. PMID: 24147109; PMCID: PMC3798377. |
| Liu B, Gulati AS, Cantillana V, Henry SC, Schmidt EA, Daniell X, Grossniklaus E, Schoenborn AA, Sartor RB, Taylor GA. Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation. Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15;305(8):G573-84. doi: 10.1152/ajpgi.00071.2013. Epub 2013 Aug 29. PMID: 23989005; PMCID: PMC3798734. |
| Sundaram S, Johnson AR, Makowski L. Obesity, metabolism and the microenvironment: Links to cancer. J Carcinog. 2013 Oct 9;12:19. doi: 10.4103/1477-3163.119606. PMID: 24227994; PMCID: PMC3816318. |
Former members listed above: Baron JA (retired), Henning SJ (retired), Jobin C (moved), Klaenhammer T (retired) Lund PK (moved), Plevy S (moved), Ringel Y (moved), Gracz AD (moved)