{"id":2230,"date":"2016-09-30T15:31:59","date_gmt":"2016-09-30T19:31:59","guid":{"rendered":"https:\/\/med-cgibd.sites.unc.edu\/center-members\/bohorquez-diego\/"},"modified":"2019-05-10T08:03:05","modified_gmt":"2019-05-10T12:03:05","slug":"bohorquez-diego","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cgibd\/bohorquez-diego\/","title":{"rendered":"Diego Bohorquez, PhD"},"content":{"rendered":"\n\n\n
\"Bohorquez<\/p>\n
\n

Contact Information<\/h4>\n

905 LaSalle St
\nGenome Sciences Research Bldg 1
\nRoom 2037
\nDurham, NC
\n(O) 919-684-4520
\ndiego.bohorquez@duke.edu<\/span><\/a><\/p>\n

Website Links
\nwww.gutbrains.com<\/a><\/h4>\n

PubMed<\/span><\/a><\/p>\n<\/div>\n<\/td>\n

Assistant Professor of Medicine
\nDepts. of Gastroenterology & Neurobiology
\nDuke University
\n<\/span><\/strong><\/span><\/p>\n

Research Summary<\/strong><\/h4>\n

Diego Boh\u00f3rquez and his colleagues developed a transgenic mouse in which enteroendocrine cells of the distal ileum and colon are fluorescent and discovered prominent cytoplasmic appendages in these cells. Dr. Boh\u00f3rquez subsequently coined the term neuropod to refer to these appendages.\u00a0 The development of this transgenic mouse model helped to identify, isolate, and study these gut sensory epithelial cells. In September 2018, his laboratory published an article in Science<\/em> documenting a new mechanism for the gut to transduce a sense to the brain in milliseconds. This newly uncovered sensory transduction mechanism uses glutamate as a neurotransmitter. It involves a synapse between enteroendocrine cells and vagal neurons. This research has been widely cited in the scientific and popular press.<\/p>\n

Relevance of Research to CGIBD Mission: <\/strong>\u00a0Dr. Bohorquez identified a gut brain neuro epithelial circuit that \u00a0may modulate brain function and behavior,\u00a0 The research is relevant to the mission of the CGIBD and to the understanding of important digestive disorders.<\/p>\n

Pilot\/Feasibility Award 2015<\/strong><\/p>\n

CGIBD Focus Area(s):\u00a0\u00a0<\/strong>Regeneration\/Repair<\/p>\n

\u00a0<\/span><\/p>\n

 <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Contact Information 905 LaSalle St Genome Sciences Research Bldg 1 Room 2037 Durham, NC (O) 919-684-4520 diego.bohorquez@duke.edu Website Links www.gutbrains.com PubMed Assistant Professor of Medicine Depts. of Gastroenterology & Neurobiology Duke University Research Summary Diego Boh\u00f3rquez and his colleagues developed a transgenic mouse in which enteroendocrine cells of the distal ileum and colon are fluorescent … Read more<\/a><\/p>\n","protected":false},"author":37775,"featured_media":4747,"parent":0,"menu_order":17,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2230","page","type-page","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nDiego Bohorquez, PhD | Center for Gastrointestinal Biology and Disease<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" 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