{"id":2255,"date":"2012-08-14T19:50:00","date_gmt":"2012-08-14T23:50:00","guid":{"rendered":"https:\/\/med-cgibd.sites.unc.edu\/center-members\/galanko-joseph\/"},"modified":"2021-01-19T15:38:30","modified_gmt":"2021-01-19T20:38:30","slug":"garcia-victor","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cgibd\/garcia-victor\/","title":{"rendered":"J. Victor Garcia-Martinez, PhD"},"content":{"rendered":"\n\n\n
\u00a0\"Garcia\"<\/span><\/p>\n
\n

Contact Information<\/h4>\n

2043 Genetic Medicine\u00a0Bldg.
\nCB #7042
\nUniversity of North Carolina at Chapel Hill
\nChapel Hill NC 27599-7042
\n(O)919-843-9600<\/p>\n

victor_garcia@med.unc.edu<\/a><\/p>\n

Web Links<\/p>\n

PubMed<\/a><\/p>\n<\/div>\n<\/td>\n

Professor
\nDept. of Medicine, Division of Infectious Disease
\nOliver Smithies Investigator
\nDirector of the International Center for the Advancement of Translational Science
\nSchool of Medicine
\nUniversity of North Carolina at Chapel Hill <\/span><\/strong><\/span><\/span><\/p>\n

Research Summary
\n<\/strong><\/span>Victor Garcia is a Professor in the Departments of Medicine and Microbiology\/Immunology. He has directed a large research laboratory at UNC (since 2009) and at the University of Texas Southwestern Medical Center at Dallas (1999-2009). He is a leader in research on the in vivo<\/em> analysis of cancer, HIV transmission and prevention using novel humanized animal models developed in his laboratory. He published a landmark paper describing the development of the BLT humanized mouse model and demonstrating its ability to mount specific adaptive and innate immune responses to EBV. BLT mice have been used to address key questions regarding a variety of aspects of the human immune response to human specific cancer-causing pathogens, to study prevention and to study HIV latency and eradication. He currently uses GF NOD\/SCID\/IL-2Rgamma chain deficient (NSG) mice transplanted with human liver (or stem cells) and thymus tissue to create gnotobiotic \u201cimmunologically humanized\u201d mice to explore influences of microbiota on HIV infection and gut-brain inflammatory interactions.<\/p>\n

Relevance of Research to CGIBD Mission: <\/strong>\u00a0Dr. Garcia-Martinez uses immunologically humanized mice to understand the influence of microbes on HIV infection and gut brain inflammation interactions.<\/p>\n

CGIBD Focus Area(s):\u00a0\u00a0<\/strong>Microbiome<\/p>\n

Collaborators:\u00a0\u00a0<\/strong>Sartor<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

<\/div>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u00a0 Contact Information 2043 Genetic Medicine\u00a0Bldg. CB #7042 University of North Carolina at Chapel Hill Chapel Hill NC 27599-7042 (O)919-843-9600 victor_garcia@med.unc.edu Web Links PubMed Professor Dept. of Medicine, Division of Infectious Disease Oliver Smithies Investigator Director of the International Center for the Advancement of Translational Science School of Medicine University of North Carolina at Chapel … Read more<\/a><\/p>\n","protected":false},"author":10853,"featured_media":4747,"parent":0,"menu_order":32,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2255","page","type-page","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nJ. 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