{"id":6266,"date":"2021-02-11T12:50:18","date_gmt":"2021-02-11T17:50:18","guid":{"rendered":"https:\/\/www.med.unc.edu\/cgibd\/?page_id=6266"},"modified":"2021-02-11T12:52:45","modified_gmt":"2021-02-11T17:52:45","slug":"hursting-stephen","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cgibd\/hursting-stephen\/","title":{"rendered":"Stephen D. Hursting, PhD, MPH"},"content":{"rendered":"<p><!-- portlet_header --><\/p>\n<p><!-- portlet_above --><\/p>\n<p><!-- description --><\/p>\n<table style=\"width: 100%\" border=\"0\">\n<tbody>\n<tr>\n<th style=\"width: 19.3022%;vertical-align: top\" valign=\"top\" width=\"260\"><a href=\"https:\/\/www.med.unc.edu\/cgibd\/wp-content\/uploads\/sites\/466\/2021\/02\/Stephen-Hursting-directory.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-6267\" src=\"https:\/\/www.med.unc.edu\/cgibd\/wp-content\/uploads\/sites\/466\/2021\/02\/Stephen-Hursting-directory-300x290.jpg\" alt=\"\" width=\"300\" height=\"290\" srcset=\"https:\/\/www.med.unc.edu\/cgibd\/wp-content\/uploads\/sites\/466\/2021\/02\/Stephen-Hursting-directory-300x290.jpg 300w, https:\/\/www.med.unc.edu\/cgibd\/wp-content\/uploads\/sites\/466\/2021\/02\/Stephen-Hursting-directory-600x580.jpg 600w, https:\/\/www.med.unc.edu\/cgibd\/wp-content\/uploads\/sites\/466\/2021\/02\/Stephen-Hursting-directory.jpg 738w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<div class=\"smallFont\">\n<h4>Contact Information<\/h4>\n<p>The University of North Carolina at Chapel Hill<br \/>\n2115B Michael Hooker Research Center<br \/>\nCB#7461<br \/>\n(O) 919-966-7346<\/p>\n<p><a class=\"email-link\" title=\"\" href=\"hursting@email.unc.edu\" rel=\"noopener noreferrer\">hursting@email.unc.edu<\/a><\/p>\n<h4>Website Links<\/h4>\n<p><a class=\"pub\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=hursting+stephen%5BAuthor%5D\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed<\/a><\/p>\n<h4><\/h4>\n<\/div>\n<\/th>\n<th style=\"vertical-align: top;width: 80.6236%\" valign=\"top\">\n<div style=\"text-align: left\"><span class=\"largeFont\"><span class=\"largeFont\"><strong><span class=\"blue\">Professor<\/span><\/strong><\/span><\/span><\/div>\n<div style=\"text-align: left\"><span class=\"largeFont\"><span class=\"largeFont\"><strong><span class=\"blue\">Department of Nutrition<\/span><\/strong><\/span><\/span><\/div>\n<div style=\"text-align: left\"><span class=\"largeFont\"><span class=\"largeFont\"><strong><span class=\"blue\">UNC Gillings School of Global Public Health<br \/>\nUniversity of North Carolina at Chapel Hill<\/span><\/strong><\/span><\/span><\/div>\n<div><\/div>\n<\/p>\n<p style=\"text-align: left\"><strong>Research Summary<\/strong><\/p>\n<p style=\"text-align: left\">Stephen Hursting, PhD, MPH, is an international leader in the area of nutrition, obesity, metabolism and cancer. His lab focuses on the molecular and metabolic mechanisms underlying obesity-cancer associations, and the impact of obesity- energy balance modulation (eg, calorie restriction and exercise) or pharmacologic agents on cancer development, progression, and responses to chemotherapy. Primarily using genetically engineered mouse models of breast cancer (recently in parallel with several clinical trials), colon cancer and pancreatic cancer, Hursting has identified the IGF1\/Akt\/mTOR and NF-kB signaling pathways as key targets for breaking the obesity-cancer link. His publications establish causal links between obesity, cancer and several systemic factors (including IGF-1, insulin, leptin and IL-6) and components of their downstream signaling pathways (including mTOR and NF-kb).<\/p>\n<p>&nbsp;<\/th>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Contact Information The University of North Carolina at Chapel Hill 2115B Michael Hooker Research Center CB#7461 (O) 919-966-7346 hursting@email.unc.edu Website Links PubMed Professor Department of Nutrition UNC Gillings School of Global Public Health University of North Carolina at Chapel Hill Research Summary Stephen Hursting, PhD, MPH, is an international leader in the area of nutrition, &hellip; <a href=\"https:\/\/www.med.unc.edu\/cgibd\/hursting-stephen\/\" aria-label=\"Read more about Stephen D. Hursting, PhD, MPH\">Read more<\/a><\/p>\n","protected":false},"author":87626,"featured_media":4747,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-6266","page","type-page","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Stephen D. Hursting, PhD, MPH | Center for Gastrointestinal Biology and Disease<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cgibd\/hursting-stephen\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stephen D. 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