Available clinical trials in the UNC Department of Pediatrics vary by division, specialty or center. Additional information about clinical trials and their availability may be found by visiting Research for Me<\/a>, which is administered by the North Carolina Translational and Clinical Sciences Institute (NCTraCS), or ClinicalTrials.gov<\/a>. For divisions with active or ongoing clinical trials, experienced research teams include both clinicians and coordinators who specialize in care and management of pediatric populations impacted by common or rare diseases.<\/p>\n It is important to note that while some clinical trials are open and enrolling, others are closed or maintain waitlists for prospective participants. Also, some clinical trials are administered by faculty from the Department of Pediatrics, but only recruit adults.<\/p>\n\n
| Area of Study<\/th> | Study Title<\/th> | Target Age<\/th> | Contact Information<\/th>\n<\/tr>\n<\/thead>\n |
|---|---|---|---|
| Adolescent Health and Well-Being<\/td> | Cognition and Neuroimaging in Teens<\/a><\/td> | Elementary, Teen<\/td> | Hannah Waltz \n919-843-9671<\/td>\n<\/tr>\n |
| Adolescent Health and Well-Being<\/td> | EVOLVE Study: Understanding risk for depression in the pubertal transition<\/a><\/td> | Elementary, Teen<\/td> | Elizabeth Andersen \nevolvestudy@unc.edu<\/td>\n<\/tr>\n |
| Adolescent Health and Well-Being<\/td> | ProNET: Psychosis Risk Outcomes Network<\/a><\/td> | Elementary, Teen<\/td> | Jennifer Nieri \njennifer_nieri@med.unc.edu \n877-774-6319<\/td>\n<\/tr>\n |
| Adolescent Health and Well-Being<\/td> | Teen Cycle Study<\/a><\/td> | Teen<\/td> | Ariana Davis \nariana.davis@unc.edu<\/td>\n<\/tr>\n |
| Adolescent Health and Well-Being<\/td> | Adolescent Mood during Puberty and Testosterone (AMPT)<\/a><\/td> | Teen<\/td> | Kayla Jensen \nNERDlab@unc.edu \n919-445-6815<\/td>\n<\/tr>\n |
| Adolescent Health and Well-Being<\/td> | Teens, Emotions, and Social Interactions Study<\/a><\/td> | Teen<\/td> | Cope Feurer \nTeenEmotionStudy@med.unc.edu \n919-966-0861<\/td>\n<\/tr>\n |
| Allergies<\/td> | Hydrolyzed Formula in Infants and Children with Cow's Milk Allergy<\/a><\/td> | Infant, Preschool, Elementary<\/td> | Lauren Herlihy \nfoodallergy@unc.edu<\/td>\n<\/tr>\n |
| Allergies<\/td> | UNC Food Allergy Registry<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Lauren Herlihy \nfoodallergy@unc.edu<\/td>\n<\/tr>\n |
| Asthma<\/td> | UNC Asthma Registry for Kids<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Miriam Davis \n919-966-2333<\/td>\n<\/tr>\n |
| Asthma<\/td> | EAGLE: Efficacy Assessment in recurrent wheezing children<\/a><\/td> | Elementary, Teen, Adult<\/td> | Sheila Joshi \nSheila_Joshi@unc.edu \n919-843-1577<\/td>\n<\/tr>\n |
| Asthma<\/td> | Individualizing Treatment for Asthma in Primary Care<\/a><\/td> | Teen, Adult<\/td> | iTREAT_Study@unc.edu \n919-843-4401<\/td>\n<\/tr>\n |
| Behavior and Development<\/td> | Spectra Discovery<\/a><\/td> | Preschool, Elementary<\/td> | Regan Burney \nspectra@unc.edu \n919-966-8598<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | ACL Research Study<\/a><\/td> | Teen, Adult<\/td> | Devin Kelly \northoresearch@med.unc.edu<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | ACL Surgery Rehabilitation Study<\/a><\/td> | Teen, Adult<\/td> | Troy Blackburn \ntroyb@email.unc.edu<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | Biomechanical Changes Following ACL Injury that Influence PTOA<\/a><\/td> | Teen, Adult<\/td> | Brian Pietrosimone \npietrosi@email.unc.edu<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | Virtual Reality ACL Reconstruction Study<\/a><\/td> | Teen<\/td> | Shelby Baez \nsbaez@unc.edu<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | Improving Walking Patterns in Individuals with an ACL Reconstruction<\/a><\/td> | Teen, Adult<\/td> | Cortney Armitano \n919-962-0396<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | Brain Function after ACL Reconstruction<\/a><\/td> | Teen, Adult<\/td> | Shelby Baez \nsbaez@unc.edu<\/td>\n<\/tr>\n |
| Bones, Joints and Muscles<\/td> | Simple Bone Cysts in Kids (SBoCK)<\/a><\/td> | Preschool, Elementary, Teen, Adult<\/td> | Julie Titter \n919-966-5495<\/td>\n<\/tr>\n |
| Cancer<\/td> | Administration of Autologous CAR-T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch in Patient with Acute Lymphoblastic Leukemia<\/a><\/td> | Preschool, Elementary, Teen, Adult<\/td> | Catherine Cheng \nSpencer Laing \n919-445-4208<\/td>\n<\/tr>\n |
| Cancer<\/td> | Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Juanita Ramirez \n877-668-0683<\/td>\n<\/tr>\n |
| Cancer<\/td> | ETERNITY: Biorepository to accelerate advances in Radiation Therapy<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Melissa Knutsen \n919-966-4432<\/td>\n<\/tr>\n |
| Cancer<\/td> | Expanded Access Protocol Using 131I-MIBG<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Juanita Ramirez \n919-966-5785 <\/td>\n<\/tr>\n |
| Cancer<\/td> | A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Kimberly Kasow \n919-966-1178<\/td>\n<\/tr>\n |
| Cancer<\/td> | Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed\/Refractory Neuroblastoma<\/a><\/td> | Preschool, Elementary, Teen, Adult<\/td> | Catherine Cheng \nSpencer Laing \n919-445-4208<\/td>\n<\/tr>\n |
| Cancer<\/td> | Study of CD30 CAR for Relapsed\/Refractory CD30+ HL and CD30+ NHL<\/a><\/td> | Preschool, Elementary, Teen, Adult<\/td> | Catherine Cheng \nSpencer Laing \n919-445-4208<\/td>\n<\/tr>\n |
| Cancer<\/td> | A study to test an oral medicine, belumosudil, in combination with corticosteroids in participants at least 12 years of age with newly diagnosed chronic graft versus host disease.<\/a><\/td> | Teen, Adult<\/td> | Janell Markey \njanell_markey@med.unc.edu<\/td>\n<\/tr>\n |
| Cancer<\/td> | Understanding Outcome Differences in Adolescents and Young Adults with Acute Lymphoblastic Leukemia (ALL)<\/a><\/td> | Teen, Adult<\/td> | cancerclinicaltrials@med.unc.edu \n919-966-4432<\/td>\n<\/tr>\n |
| Cancer<\/td> | UNC Childhood, Adolescent, and Young Adult Cancer Registry<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Andrew Smitherman, MD MSc \n andrew_smitherman@med.unc.edu \n919-966-1178<\/td>\n<\/tr>\n |
| Cancer<\/td> | Improve Adherence to Childhood Cancer Survivorship<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Lineberger Clinical Research \ncancerclinicaltrials@med.unc.edu \n919-966-4432<\/td>\n<\/tr>\n |
| Cancer<\/td> | Pediatric Oncology Tissue to Support Further Research<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Lineberger Clinical Research \ncancerclinicaltrials@med.unc.edu \n919-966-4432<\/td>\n<\/tr>\n |
| Cancer<\/td> | Measuring body composition in childhood cancer<\/a><\/td> | Elementary, Teen, Adult<\/td> | Lineberger Clinical Research \ncancerclinicaltrials@med.unc.edu \n919-966-4432<\/td>\n<\/tr>\n |
| COVID-19<\/td> | The PREVNC Study<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Katie Mills \nPREVNCstudy@unc.edu<\/td>\n<\/tr>\n |
| COVID-19<\/td> | Long-term immunologic responses to COVID-19 infection and vaccination<\/a><\/td> | Elementary, Teen, Adult<\/td> | Usaphea P. Vanna \nusaphea@ad.unc.edu<\/td>\n<\/tr>\n |
| Dental Health<\/td> | water from Bottles to Establish Strong Teeth (waterBEST)<\/a><\/td> | Infant<\/td> | Sonya K Capps \nsonya_capps@unc.edu \n919-537-3269<\/td>\n<\/tr>\n |
| Dental Health<\/td> | Dental Anxiety in Young Dental Patients<\/a><\/td> | Preschool, Elementary<\/td> | Nare Ghaltakhchyan \njlab@unc.edu \n984-234-1858<\/td>\n<\/tr>\n |
| Developmental Disorders<\/td> | IBIS Early Prediction Study<\/a><\/td> | Infant, Preschool<\/td> | Shannon Sweeney \n919-843-1331<\/td>\n<\/tr>\n |
| Developmental Disorders<\/td> | Registry for Autism, Fragile X Syndrome, and Intellectual and Developmental Disabilities<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Renee Clark \n919-966-5232<\/td>\n<\/tr>\n |
| Developmental Disorders<\/td> | FLASH Study<\/a><\/td> | Infant, Preschool<\/td> | Jessica Steinbrenner \nflash_study@unc.edu<\/td>\n<\/tr>\n |
| Developmental Disorders<\/td> | Comparing executive functioning in children with or without ADHD or ASD<\/a><\/td> | Elementary<\/td> | Clare Harrop \nclare_harrop@med.unc.edu<\/td>\n<\/tr>\n |
| Developmental Disorders<\/td> | Studying brain development in infants with developmental disorders<\/a><\/td> | Infant, Preschool<\/td> | Julia Gross \njulia_gross@med.unc.edu \n919-966-8032<\/td>\n<\/tr>\n |
| Developmental Disorders<\/td> | Ethnic-Racial Socialization Practices among Black Youth with Neurodevelopmental Disabilities<\/a><\/td> | Elementary, Teen, Adult<\/td> | Nicole Telfer \nblackfamiliesstudy@unc.edu<\/td>\n<\/tr>\n |
| Diabetes<\/td> | Type 1 Diabetes Registry<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Klara Klein \nklara_klein@med.unc.edu<\/td>\n<\/tr>\n |
| Diabetes<\/td> | Developing treatments for type 1 diabetes<\/a><\/td> | Elementary, Teen, Adult<\/td> | Roland Tisch \n919-966-4766<\/td>\n<\/tr>\n |
| Down Syndrome<\/td> | IBIS Down Syndrome Imaging Study<\/a><\/td> | Infant, Preschool<\/td> | Shannon Sweeney \n919-843-1331<\/td>\n<\/tr>\n |
| Ear, Nose and Throat<\/td> | Cochlear Implants for Babies and Toddlers with Single-Sided Deafness<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Michelle Bocanegra \nCIResearch@unc.edu<\/td>\n<\/tr>\n |
| Eating, Nutrition, and Metabolism<\/td> | An avocado intervention to increase the nutrient quality of human milk in support of infant cognitive development.<\/a><\/td> | Infant, Adult<\/td> | Mandi Rider \nfeedingbrains@unc.edu<\/td>\n<\/tr>\n |
| Eating, Nutrition, and Metabolism<\/td> | Minds & Milkshakes<\/a><\/td> | Teen<\/td> | Brian Brown \nNIBL@unc.edu<\/td>\n<\/tr>\n |
| Eating, Nutrition, and Metabolism<\/td> | ARFID Genes and Environment<\/a><\/td> | Elementary, Teen, Adult<\/td> | Melissa Chernoff \nmelissa_chernoff@med.unc.edu<\/td>\n<\/tr>\n |
| Eczema<\/td> | Eczema Research Study<\/a><\/td> | Elementary, Teen, Adult<\/td> | Lauren Herlihy \nlekoch@email.unc.edu<\/td>\n<\/tr>\n |
| Eosinophilic Esophagitis<\/td> | EoE Tooth Fairy Study: Environmental Risk Factors for Eosinophilic Esophagitis (EoE)<\/a><\/td> | Preschool, Elementary, Teen,<\/td> | Kacie Walker \ntoothfairystudy@med.unc.edu<\/td>\n<\/tr>\n |
| Eosinophilic Esophagitis<\/td> | Individualized Diet Elimintation for Treatment of Eosinophilic Esophagitis (EoE)<\/a><\/td> | Teen, Adult<\/td> | Tim Gee \ntimothy_gee@med.unc.edu<\/td>\n<\/tr>\n |
| Eosinophilic Gastritis<\/td> | Eosinophilic Gastritis Study<\/a><\/td> | Teen, Adult<\/td> | Hiwot Ekuban \nhiwot_ekuban@med.unc.edu<\/td>\n<\/tr>\n |
| Hearing Loss<\/td> | Vestibular\/Balance and Hearing Loss Study<\/a><\/td> | Elementary<\/td> | Graham Cochrane \ngraham.cochrane@unchealth.unc.edu \n401-862-2263<\/td>\n<\/tr>\n |
| Hearing Loss<\/td> | Children with Hearing Loss Sleep Study<\/a><\/td> | Elementary<\/td> | Julia Drouin \nallearslab@med.unc.edu<\/td>\n<\/tr>\n |
| Inflammatory, Allergic, and Chronic Gastrointestinal Diseases<\/td> | Tissue Repository for Inflammatory & Allergic Chronic GI diseases<\/a><\/td> | Infant, Preschool, Elementary, Teen<\/td> | Gwen Lau \ngwen_lau@med.unc.edu \n919-843-8107<\/td>\n<\/tr>\n |
| Inflammatory Bowel Disease<\/td> | The Pediatric IBD Network Improvement Collaborative<\/a><\/td> | Preschool, Elementary, Teen, Adult<\/td> | Paris Bennett \nparis_bennett@med.unc.edu<\/td>\n<\/tr>\n |
| Kidney Disease<\/td> | CureGN (Cure Glomerulonephropathy)<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Maggie D'Angelo \n919-619-1773<\/td>\n<\/tr>\n |
| Kidney Disease<\/td> | GDCN Registry<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Kristin Brock \n919-445-2623<\/td>\n<\/tr>\n |
| Kidney Disease<\/td> | Evaluating Problematic Proteinuria in Kids (EPPIK)<\/a><\/td> | Infant, Preschool, Elementary, Teen<\/td> | Anne Froment \nkidneytrials@unc.edu \n919-445-2622<\/td>\n<\/tr>\n |
| Medication and Vaccine Efficacy<\/td> | Pharmacokinetics and Safety of Drugs in Lactating Women and Breastfed Infants<\/a><\/td> | Infant, Teen, Adult<\/td> | Jennifer Talbert \n984-974-7865 \njtalbert@med.unc.edu<\/td>\n<\/tr>\n |
| Medication and Vaccine Efficacy<\/td> | Pharmacokinetics of Off Label Pediatric Medications<\/a><\/td> | Infant, Preschool, Elementary<\/td> | Jennifer Talbert \n984-974-7865 \njtalbert@med.unc.edu<\/td>\n<\/tr>\n |
| Medication and Vaccine Efficacy<\/td> | Safety of Sildenafil in Premature Infants (SIL02)<\/a><\/td> | Infant<\/td> | Jennifer Talbert \n984-974-7865 \njtalbert@med.unc.edu<\/td>\n<\/tr>\n |
| Medication and Vaccine Efficacy<\/td> | Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS or POP02)<\/a><\/td> | Infant, Preschool, Elementary, Teen, Adult<\/td> | Jennifer Talbert \n984-974-7865 \njtalbert@med.unc.edu<\/td>\n<\/tr>\n |
| Mental and Emotional Health<\/td> | The Life Experiences and Emotion Development (LEED) Study<\/a><\/td> | Elementary<\/td> | Adam Miller \nLEEDstudy@rti.org \n910-477-3712<\/td>\n<\/tr>\n |
| Mental and Emotional Health<\/td> | Suicide Prevention Study For Black Youth<\/a><\/td> | Teen, Adult<\/td> | Sonyia Richardson \nscopelan@unc.edu<\/td>\n<\/tr>\n |
| Multiple Scelrosis<\/td> | Pediatric Relapsing Remitting Multiple Sclerosis Study<\/a><\/td> | Elementary, Teen, Adult<\/td> | Patricia Orozco \n 919-966-5039<\/td>\n<\/tr>\n |
| Nephrotic Syndrome<\/td> | INShore: is the drug obinutizumab helpful in children with nephrotic syndrome?<\/a><\/td> | Preschool, Elementary, Teen, Adult<\/td> | Fernanda Ochoa Toro \nferoacha@med.unc.edu<\/td>\n<\/tr>\n |
| Neurodevelopment<\/td> | Early Life Factors (ELF) Study<\/a><\/td> | Infant, Adult<\/td> | Thao Nguyen \nELFstudy@unc.edu \n919-445-2869<\/td>\n<\/tr>\n |
| Nutrition<\/td> | Infant Nutrition & Cognition Study<\/a><\/td> | Infant, Adult<\/td> | Melissa Shaffer \n704-250-5018<\/td>\n<\/tr>\n |
| Obesity<\/td> | UNC Nutritional Research Institute Children Health Study<\/a><\/td> | Elementary, Teen, Adult<\/td> | Brea Nance \n704-250-5055<\/td>\n<\/tr>\n |
| Osteoarthritis<\/td> | Move with Support - Muevete con Apoyo<\/a><\/td> | Teen, Adult<\/td> | Sandra Soto \n919-966-4298<\/td>\n<\/tr>\n |
| Sickle Cell Disease<\/td> | Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation<\/a><\/td> | Preschool, Elementary<\/td> | Kimberly Kasow \n919-966-1178<\/td>\n<\/tr>\n |
| Speech, Dentofacial Abnormalities<\/td> | Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses (OSP)<\/a><\/td> | Teen, Adult<\/td> | Sherrill Phillips \nsherrill_phillips@unc.edu\t<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n","protected":false},"excerpt":{"rendered":" |