{"id":3184,"date":"2019-05-16T15:20:23","date_gmt":"2019-05-16T19:20:23","guid":{"rendered":"https:\/\/www.med.unc.edu\/childrensresearch\/?page_id=3184"},"modified":"2024-06-10T12:22:53","modified_gmt":"2024-06-10T16:22:53","slug":"cancer-and-blood-disorders","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/childrensresearch\/research\/areas-of-research\/cancer-and-blood-disorders\/","title":{"rendered":"Cancer and Blood Disorders"},"content":{"rendered":"<div class=\"department-intro\"><div class=\"wc-theme-box\"><h1>Cancer and Blood Disorders\n             <\/h1>\n<\/div><\/div>\n<h4>About Our Research<\/h4>\n<p>Research efforts within the Division of Hematology-Oncology include projects involving: bleeding and clotting disorders, childhood cancers, hemophilia A, hemophilia B, sickle cell disease, leukemia, lymphoma, health disparities, solid tumors, bone marrow transplant, hematopoietic stem cell transplant, long-term effects of cancer treatments, T-cell therapy, supportive care to survivors of childhood cancer, and many more.<\/p>\n<p>Our faculty collaborates in these projects with colleagues across campus, including researchers working throughout the School of Medicine, Lineberger Comprehensive Cancer Center, the Gillings School of Global Public Health, and the Eshelman School of Pharmacy. The division is also a member of the Children\u2019s Oncology Group, a national consortium of pediatric cancer centers.<\/p>\n<h4>Ongoing Clinical Trials and Studies<\/h4>\n<ul>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01351545\" target=\"_blank\" rel=\"noopener noreferrer\">A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)<\/a><\/li>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03016377\" target=\"_blank\" rel=\"noopener noreferrer\">Administration of Autologous CAR-T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch in Patient with Acute Lymphoblastic Leukemia<\/a><\/li>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04018937\" target=\"_blank\" rel=\"noopener noreferrer\">Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation<\/a><\/li>\n<li><a href=\"https:\/\/researchforme.unc.edu\/index.php\/en\/study-details?rcid=3053\" target=\"_blank\" rel=\"noopener\">UNC Childhood, Adolescent, and Young Adult Cancer Registry<\/a><\/li>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01590680\" target=\"_blank\" rel=\"noopener noreferrer\">Expanded Access Protocol Using 131I-MIBG<\/a><\/li>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03155620\" target=\"_blank\" rel=\"noopener noreferrer\">Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)<\/a><\/li>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02690545\" target=\"_blank\" rel=\"noopener noreferrer\">Study of CD30 CAR for Relapsed\/Refractory CD30+ HL and CD30+ NHL<\/a><\/li>\n<li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03721068?\" target=\"_blank\" rel=\"noopener noreferrer\">Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed\/Refractory Neuroblastoma<\/a><\/li>\n<li><a href=\"https:\/\/researchforme.unc.edu\/index.php\/en\/study-details?rcid=1771\" target=\"_blank\" rel=\"noopener\">Understanding Outcome Differences in Adolescents and Young Adults with Acute Lymphoblastic Leukemia (ALL)<\/a><\/li>\n<li><a href=\"https:\/\/researchforme.unc.edu\/index.php\/en\/study-details?rcid=4732\" target=\"_blank\" rel=\"noopener\">Improve Adherence to Childhood Cancer Survivorship<\/a><\/li>\n<li><a href=\"https:\/\/researchforme.unc.edu\/index.php\/en\/study-details?rcid=789\" target=\"_blank\" rel=\"noopener\">Pediatric Oncology Tissue to Support Further Research<\/a><\/li>\n<\/ul>\n<h4>Our Researchers<\/h4>\n<div class=\"container-fluid divisions-container multi-column\">\n    \n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/03\/Abajas.jpg\" alt=\"Yasmina Abajas, MD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/03\/Abajas.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/childrensresearch\/directory\/yasmina-abajas\/\" rel=\"bookmark\">\n                            Yasmina Abajas, MD                        <\/a>\n                                    <\/h2> \n                \n                                                                                                <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/03\/Alexander.jpg\" alt=\"Thomas Alexander, MD, MPH\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/03\/Alexander.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/childrensresearch\/directory\/thomas-alexander-md-mph\/\" rel=\"bookmark\">\n                            Thomas Alexander, MD, MPH                        <\/a>\n                                    <\/h2> \n                \n                                                                                                <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/03\/IanDavis300.jpg\" alt=\"Ian Davis, MD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/03\/IanDavis300.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/childrensresearch\/directory\/ian-davis-md-phd\/\" rel=\"bookmark\">\n                            Ian Davis, MD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                                                <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/04\/12017.jpg\" alt=\"Barbara Savoldo, MD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/04\/12017.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/childrensresearch\/directory\/barbara-savoldo-md-phd\/\" rel=\"bookmark\">\n                            Barbara Savoldo, MD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                                                <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/04\/Smitherman-1024x683.jpg\" alt=\"Andrew Smitherman, MD, MS\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/04\/Smitherman-1024x683.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/childrensresearch\/directory\/andrew-smitherman-md-ms\/\" rel=\"bookmark\">\n                            Andrew Smitherman, MD, MS                        <\/a>\n                                    <\/h2> \n                \n                                                                                                <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/06\/Westmoreland.jpeg\" alt=\"Kate Westmoreland, MD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/childrensresearch\/wp-content\/uploads\/sites\/967\/2019\/06\/Westmoreland.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/childrensresearch\/directory\/kate-westmoreland-md\/\" rel=\"bookmark\">\n                            Kate Westmoreland, MD                        <\/a>\n                                    <\/h2> \n                \n                                                                                                <\/div>\n        <\/article>\n\n    \n    <script type=\"text\/javascript\">\n        (function($){\n            var entries = $('.entry-content');\n                entries.each(function(index, entry ){\n                    if( $(entry).find('.post-author').length === 0 ) {\n 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more<\/a><\/p>\n","protected":false},"author":79819,"featured_media":0,"parent":2461,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"templates\/front-page.php","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-3184","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cancer and Blood Disorders - UNC Children&#039;s Research Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/childrensresearch\/research\/areas-of-research\/cancer-and-blood-disorders\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cancer and Blood 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