{"id":30,"date":"2024-01-24T09:25:39","date_gmt":"2024-01-24T14:25:39","guid":{"rendered":"https:\/\/www.med.unc.edu\/cidd\/research\/for-research-participants\/join-now\/ct-and-as-studies\/"},"modified":"2025-12-02T20:31:55","modified_gmt":"2025-12-03T01:31:55","slug":"ct-and-as-studies","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cidd\/research\/for-research-participants\/participate-in-our-research\/ct-and-as-studies\/","title":{"rendered":"Clinical Trial and Angelman Syndrome Studies"},"content":{"rendered":"<h2 class=\"www-somHeader\">Clinical Trials Program<\/h2>\n<p>The <strong> CIDD Clinical Trials Program<\/strong> was founded in 2018 by <a href=\"https:\/\/markshenlab.org\/\">Mark Shen, PhD,<\/a> and a team of interdisciplinary clinicians and researchers. Since then, the program has grown exponentially and conducts clinical trials and observational research on a range of genetic and neurodevelopmental conditions. The CIDD Clinical Trials Program supports industry, federal, foundation, and investigator-initiated research, working collaboratively with investigators and funders to conduct innovative clinical trials effectively while prioritizing patient care. Our team consists of specialized investigators, research coordinators, and administrative support to assist with regulatory compliance, finances, and quality oversight.<\/p>\n<hr \/>\n<h2 class=\"www-somHeader\">Angelman Syndrome Research Program<\/h2>\n<p>The <strong>Angelman Syndrome Research Program<\/strong> was founded by an interdisciplinary team of researchers focused on improving the lives of individuals with Angelman syndrome. Our Angelman syndrome research includes both basic research and drug discovery projects, with the expectation that our innovative discoveries will lead to new therapeutics for Angelman syndrome.<\/p>\n<p>We encourage you to explore below to learn more about our research teams, and to choose a research study you are interested in joining.<\/p>\n<som-cell cell-info=\"{&quot;ID&quot;:1112,&quot;post_author&quot;:&quot;112631&quot;,&quot;post_date&quot;:&quot;2024-07-25 15:46:43&quot;,&quot;post_date_gmt&quot;:&quot;2024-07-25 19:46:43&quot;,&quot;post_content&quot;:&quot;&quot;,&quot;post_title&quot;:&quot;CT and AS Studies &#8211; Content Boxes&quot;,&quot;post_excerpt&quot;:&quot;&quot;,&quot;post_status&quot;:&quot;publish&quot;,&quot;comment_status&quot;:&quot;open&quot;,&quot;ping_status&quot;:&quot;closed&quot;,&quot;post_password&quot;:&quot;&quot;,&quot;post_name&quot;:&quot;ct-and-as-studies-content-boxes&quot;,&quot;to_ping&quot;:&quot;&quot;,&quot;pinged&quot;:&quot;&quot;,&quot;post_modified&quot;:&quot;2026-02-05 10:13:06&quot;,&quot;post_modified_gmt&quot;:&quot;2026-02-05 15:13:06&quot;,&quot;post_content_filtered&quot;:&quot;&quot;,&quot;post_parent&quot;:0,&quot;guid&quot;:&quot;https:\\\/\\\/www.med.unc.edu\\\/cidd\\\/cell\\\/ct-and-as-studies-content-boxes\\\/&quot;,&quot;menu_order&quot;:0,&quot;post_type&quot;:&quot;somcell&quot;,&quot;post_mime_type&quot;:&quot;&quot;,&quot;comment_count&quot;:&quot;0&quot;,&quot;filter&quot;:&quot;raw&quot;}\" cell-meta=\"{&quot;_upd_sortorder&quot;:[&quot;1&quot;],&quot;layout&quot;:[&quot;RepeatableBoxes&quot;],&quot;cellInformation&quot;:[&quot;{\\&quot;singleCellBlocks\\&quot;:{},\\&quot;repeatableBoxes\\&quot;:[{\\&quot;includeLink\\&quot;:1,\\&quot;boxText\\&quot;:\\&quot;CIDD Research for Me\\&quot;,\\&quot;useRichTextEditor\\&quot;:\\&quot;false\\&quot;,\\&quot;boxExcerptText\\&quot;:\\&quot;Explore this page to explore studies that are currently available at the CIDD, including Clinical Trials and Angelman Syndrome research.\\&quot;,\\&quot;boxUrl\\&quot;:\\&quot;https:\\\/\\\/researchforme.unc.edu\\\/index.php\\\/en\\\/study-list?dept=CIDD\\&quot;},{\\&quot;includeLink\\&quot;:1,\\&quot;boxUrl\\&quot;:\\&quot;https:\\\/\\\/www.angelman.org\\\/studies\\\/angelman-syndrome-natural-history-study\\\/\\&quot;,\\&quot;boxText\\&quot;:\\&quot;Angelman Syndrome Natural History Study\\&quot;,\\&quot;boxExcerptText\\&quot;:\\&quot;\\&quot;,\\&quot;useRichTextEditor\\&quot;:\\&quot;true\\&quot;,\\&quot;boxRichText\\&quot;:\\&quot;&lt;p&gt;UNC CIDD is a satellite site for the Angelman Syndrome (AS) Natural History Study (NHS), a longitudinal project that helps us understand the progression of symptoms and features associated with AS throughout an individual\\u2019s lifetime.&nbsp;&lt;\\\/p&gt;&lt;p&gt;&lt;strong&gt;Contact&lt;\\\/strong&gt;: &lt;a href=\\\\\\&quot;mailto:angelman@cidd.unc.edu\\\\\\&quot; rel=\\\\\\&quot;noopener noreferrer\\\\\\&quot; target=\\\\\\&quot;_blank\\\\\\&quot;&gt;Margaret DeRamus, MS, CCC-SLP&lt;\\\/a&gt;&lt;\\\/p&gt;\\&quot;},{\\&quot;includeLink\\&quot;:1,\\&quot;boxUrl\\&quot;:\\&quot;https:\\\/\\\/laddertotreatment.org\\\/\\&quot;,\\&quot;boxText\\&quot;:\\&quot;LADDER Learning Network\\&quot;,\\&quot;boxExcerptText\\&quot;:\\&quot;\\&quot;,\\&quot;useRichTextEditor\\&quot;:\\&quot;true\\&quot;,\\&quot;boxRichText\\&quot;:\\&quot;&lt;p&gt;UNC CIDD is a member of the LADDER to Learning Network. Linking Angelman and Dup15q Data for Expanded Research (LADDER) is a database platform that links data on individuals with Angelman or Dup15q syndromes collected from multiple sources, such as research studies, registries, caregiver reports, and clinic visits.&nbsp;&lt;\\\/p&gt;&lt;p&gt;&lt;strong&gt;Contact&lt;\\\/strong&gt;: &lt;a href=\\\\\\&quot;mailto:angelman@cidd.unc.edu\\\\\\&quot; rel=\\\\\\&quot;noopener noreferrer\\\\\\&quot; target=\\\\\\&quot;_blank\\\\\\&quot;&gt;Margaret DeRamus, MS, CCC-SLP&lt;\\\/a&gt; OR &lt;a href=\\\\\\&quot;mailto:dup15q@cidd.unc.edu\\\\\\&quot; rel=\\\\\\&quot;noopener noreferrer\\\\\\&quot; target=\\\\\\&quot;_blank\\\\\\&quot;&gt;Dup15q&lt;\\\/a&gt;.&lt;\\\/p&gt;\\&quot;},{\\&quot;includeLink\\&quot;:1,\\&quot;boxUrl\\&quot;:\\&quot;https:\\\/\\\/www.med.unc.edu\\\/cidd\\\/research\\\/for-research-participants\\\/participate-in-our-research\\\/brain-development-study-of-infants-with-angelman-syndrome-fragile-x-syndrome\\\/\\&quot;,\\&quot;boxText\\&quot;:\\&quot;Brain Development Study of Infants with Angelman Syndrome &amp; Fragile X Syndrome \\&quot;,\\&quot;boxExcerptText\\&quot;:\\&quot;UNC CIDD is recruiting infants with either Angelman syndrome or Fragile X syndrome \\u2013 under 24 months of age \\u2013 for a new research study examining brain and behavioral development from 6 to 24 months of age in order to aid in the future development of better supports and treatments.\\\\nContact: Zumin Chen (Study Coordinator)\\\\nEmail: zumin_chen@med.unc.edu\\\\nshenlab@med.unc.edu\\\\n\\&quot;,\\&quot;useRichTextEditor\\&quot;:\\&quot;true\\&quot;,\\&quot;boxRichText\\&quot;:\\&quot;&lt;p&gt;UNC CIDD is recruiting infants with either Angelman syndrome or Fragile X syndrome \\u2013 under 24 months of age \\u2013 for a new research study examining brain and behavioral development from 6 to 24 months of age in order to aid in the future development of better supports and treatments.&lt;\\\/p&gt;&lt;p&gt;&lt;strong&gt;Contact: &lt;\\\/strong&gt;&lt;a target=\\\\\\&quot;_blank\\\\\\&quot; href=\\\\\\&quot;mailto:shenlab@med.unc.edu\\\\\\&quot;&gt;shenlab@med.unc.edu&lt;\\\/a&gt;&lt;\\\/p&gt;\\&quot;}],\\&quot;boxCustomStyles\\&quot;:{\\&quot;textAlign\\&quot;:\\&quot;left\\&quot;,\\&quot;includeImage\\&quot;:0,\\&quot;includeImagePadding\\&quot;:1,\\&quot;imageAspectRatio\\&quot;:\\&quot;3\\\/2\\&quot;,\\&quot;includeLink\\&quot;:1,\\&quot;backgroundColor\\&quot;:\\&quot;lightGray\\&quot;,\\&quot;columnLayout\\&quot;:\\&quot;4\\&quot;},\\&quot;boxType\\&quot;:\\&quot;imageBoxes\\&quot;,\\&quot;boxStyleOption\\&quot;:\\&quot;content-boxes\\&quot;}&quot;],&quot;apiCallInformation&quot;:[&quot;{}&quot;]}\"><\/som-cell>\n<p>&nbsp;<\/p>\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-6 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<a class=\"btn btn-primary btn-lg  btn-block  oscitas-bootstrap-container\" target=\"_self\" href=\"https:\/\/www.med.unc.edu\/cidd\/news\/\">Our Research in the News<\/a>\n<\/div>\n<div class=\"col-lg-6 col-md-12 col-xs-12 col-sm-12 oscitas-bootstrap-container\">\n<a class=\"btn btn-primary btn-lg btn-block  oscitas-bootstrap-container\" target=\"_self\" href=\"https:\/\/www.med.unc.edu\/cidd\/research\/meet-our-researchers\/\">Meet Our Researchers<\/a>\n<\/div>\n<\/div>\n<div class=\"bs-callout bs-callout-primary\">\n<h3>Contact Us<\/h3>\n<p>For questions about the <strong>Angelman Syndrome Natural History Study<\/strong> or the <strong>LADDER Learning Network<\/strong>, contact <a href=\"mailto:angelman@cidd.unc.edu\">Margaret DeRamus<\/a>.<\/p>\n<p>For questions about the <strong>CIDD Clinical Trials Program<\/strong>, contact <a href=\"mailto:Hannah.riehl@cidd.unc.edu\">Hannah Riehl<\/a>.<\/p>\n<p>For questions about the <strong>Brain Development Study of Infants with Angelman Syndrome &amp; Fragile X Syndrome<\/strong>, contact <a href=\"mailto:shenlab@med.unc.edu\">shenlab@med.unc.edu<\/a>.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The CIDD Clinical Trials Program was founded in 2018 by Mark Shen, PhD, and a team of interdisciplinary clinicians and researchers. Since then, the program has grown exponentially and conducts clinical trials and observational research on a range of genetic and neurodevelopmental conditions. The CIDD Clinical Trials Program supports industry, federal, foundation, and investigator-initiated research, &hellip; <a href=\"https:\/\/www.med.unc.edu\/cidd\/research\/for-research-participants\/participate-in-our-research\/ct-and-as-studies\/\" aria-label=\"Read more about Clinical Trial and Angelman Syndrome Studies\">Read more<\/a><\/p>\n","protected":false},"author":79967,"featured_media":0,"parent":27,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-30","page","type-page","status-publish","hentry","odd"],"acf":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/pages\/30","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/users\/79967"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/comments?post=30"}],"version-history":[{"count":5,"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/pages\/30\/revisions"}],"predecessor-version":[{"id":2062,"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/pages\/30\/revisions\/2062"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/pages\/27"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/cidd\/wp-json\/wp\/v2\/media?parent=30"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}