BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Computational Medicine - ECPv6.15.18//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://www.med.unc.edu/compmed
X-WR-CALDESC:Events for Computational Medicine
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/New_York
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20220313T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20221106T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20230312T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20231105T060000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0500
TZOFFSETTO:-0400
TZNAME:EDT
DTSTART:20240310T070000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0400
TZOFFSETTO:-0500
TZNAME:EST
DTSTART:20241103T060000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20230112T140000
DTEND;TZID=America/New_York:20230112T150000
DTSTAMP:20260422T165922
CREATED:20230102T193740Z
LAST-MODIFIED:20230102T193740Z
UID:10000352-1673532000-1673535600@www.med.unc.edu
SUMMARY:Faculty Candidate Seminar
DESCRIPTION:Presenter: Abigail Lind\, PhD \nGladstone Institutes\, UCSF\, San Francisco\, CA \nTalk Title: From pathogens to commensals: human-associated microbial eukaryotes through the lens of genomics and evolution \n  \nHumans coexist with myriad microbes that live within and on us\, impacting our health in beneficial and detrimental ways. These microbes come from all domains of life and include bacteria\, archaea\, and eukaryotes. Eukaryotic microbes\, including protists and fungi\, are emerging as key members of the microbiome that influence other microbiota and host health in multifaceted ways. The factors that differentiate negative and positive interactions with a human host\, and mechanistically how eukaryotic microbes accomplish these impacts\, are unknown. \nI have developed methods to routinely and accurately identify eukaryotic microbes in microbiomes\, and discovered that multiple commensal protists are common members of a healthy gut. I have found that Blastocystis\, a diverse species complex of stramenopile protists\, are the most prevalent commensal gut eukaryotes worldwide and can be found in the guts of animals from insects to humans. Interestingly\, Blastocystis is closely associated with gut health\, correlating with decreased inflammation and high bacterial diversity. However\, we understand very little about the biology of this common organism\, which in the past has even been viewed as a parasite. Using comparative and functional genomics approaches in combination with mechanistic experiments on defined anaerobic cultures I investigate the function of Blastocystis and other commensal gut protists in the microbiome. These approaches have identified key biological principles of Blastocystis and in the future will determine how these common commensal gut protists interact with bacterial gut microbiota and the human host to impact health.
URL:https://www.med.unc.edu/compmed/event/faculty-candidate-seminar-11/
LOCATION:Bioinformatics Building\, Room 1131\, 130 Mason Farm Rd\, Chapel Hill\, NC\, 27514\, United States
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2023/01/Abigail-Lind-Headshot-scaled.jpeg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
END:VCALENDAR