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X-ORIGINAL-URL:https://www.med.unc.edu/compmed
X-WR-CALDESC:Events for Computational Medicine
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210618T100000
DTEND;TZID=America/New_York:20210618T110000
DTSTAMP:20260414T115341
CREATED:20210616T195612Z
LAST-MODIFIED:20210616T195612Z
UID:10000294-1624010400-1624014000@www.med.unc.edu
SUMMARY:CompMed Research in Progress
DESCRIPTION:Presenter: Tim Elston \nTalk Title: “Inferring Src kinetics from single molecule data”
URL:https://www.med.unc.edu/compmed/event/compmed-research-in-progress-2/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2021/06/Tim-Elston.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210611T100000
DTEND;TZID=America/New_York:20210611T110000
DTSTAMP:20260414T115341
CREATED:20210616T185721Z
LAST-MODIFIED:20210616T195255Z
UID:10000292-1623405600-1623409200@www.med.unc.edu
SUMMARY:CompMed Research in Progress
DESCRIPTION:Presenter: Akram Yazdani \nTalk Title: “Uncovering gene regulatory pathways and pleiotropy using Bayesian causal networks”
URL:https://www.med.unc.edu/compmed/event/compmed-research-in-progress/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2021/06/Akram-Yazdani.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210611T090000
DTEND;TZID=America/New_York:20210611T120000
DTSTAMP:20260414T115341
CREATED:20210505T164419Z
LAST-MODIFIED:20210505T164419Z
UID:10000291-1623402000-1623412800@www.med.unc.edu
SUMMARY:Clinical Data Literacy Series
DESCRIPTION:Recruitment email to send out with workshop application \nEmail subject line: Announcement – Research with EHR Data Workshop | June 7-11\, 2021 \n  \nClinical Data Literacy Series: Electronic Health Data Basics \nThe UNC Program for Precision Medicine in Health Care (PPMH)\, School of Medicine Clinical Research Support Office and NC Translational and Clinical Sciences Institute (TraCS) are organizing a hands-on virtual workshop that will introduce participants to   electronic health record (EHR) data. Content will include EHR data structure\, how to query EHR data and interpret the results and limitations of those queries\, how to deal with missing data\, and an introduction to the Carolina Data Warehouse. During the workshop\, participants will work with a de-identified EHR data set based on actual patient records. The workshop is aimed at UNC researchers\, students\, and clinicians who would like to use EHR data in research. \nThe workshop be taught via Zoom from 9am-12pm ET on Monday June 7\, Wednesday June 9\, and Friday June 11\, 2021. \nPoints to note: \n\nThe workshop is open to researchers with a current UNC-CH affiliation and onyen.\nSince the content will build upon sequential learning\, participants will be required to attend all sessions.\nA laptop or desktop computer with a second monitor is highly recommended.\nThe number of workshop participants will be limited to ensure that everyone receives adequate attention from the instructors and TAs.\nThere is no charge to attend\, but space is limited. We anticipate strong interest\, and we will from the pool of applicants.\n\n  \nApplication procedure: \nIf you are interested in attending the workshop\, fill out the application form by 9:00am Wednesday May 12\, 2021. Email precisionmedicine@med.unc.edu if you have any questions. \nWe will send out acceptance notifications the week of May 17. \n 
URL:https://www.med.unc.edu/compmed/event/clinical-data-literacy-series/2021-06-11/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2021/05/Clinical-Data-Literacy-Series.jpg
ORGANIZER;CN="PPMH":MAILTO:precisionmedicine@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210609T090000
DTEND;TZID=America/New_York:20210609T120000
DTSTAMP:20260414T115341
CREATED:20210505T164419Z
LAST-MODIFIED:20210505T164419Z
UID:10000290-1623229200-1623240000@www.med.unc.edu
SUMMARY:Clinical Data Literacy Series
DESCRIPTION:Recruitment email to send out with workshop application \nEmail subject line: Announcement – Research with EHR Data Workshop | June 7-11\, 2021 \n  \nClinical Data Literacy Series: Electronic Health Data Basics \nThe UNC Program for Precision Medicine in Health Care (PPMH)\, School of Medicine Clinical Research Support Office and NC Translational and Clinical Sciences Institute (TraCS) are organizing a hands-on virtual workshop that will introduce participants to   electronic health record (EHR) data. Content will include EHR data structure\, how to query EHR data and interpret the results and limitations of those queries\, how to deal with missing data\, and an introduction to the Carolina Data Warehouse. During the workshop\, participants will work with a de-identified EHR data set based on actual patient records. The workshop is aimed at UNC researchers\, students\, and clinicians who would like to use EHR data in research. \nThe workshop be taught via Zoom from 9am-12pm ET on Monday June 7\, Wednesday June 9\, and Friday June 11\, 2021. \nPoints to note: \n\nThe workshop is open to researchers with a current UNC-CH affiliation and onyen.\nSince the content will build upon sequential learning\, participants will be required to attend all sessions.\nA laptop or desktop computer with a second monitor is highly recommended.\nThe number of workshop participants will be limited to ensure that everyone receives adequate attention from the instructors and TAs.\nThere is no charge to attend\, but space is limited. We anticipate strong interest\, and we will from the pool of applicants.\n\n  \nApplication procedure: \nIf you are interested in attending the workshop\, fill out the application form by 9:00am Wednesday May 12\, 2021. Email precisionmedicine@med.unc.edu if you have any questions. \nWe will send out acceptance notifications the week of May 17. \n 
URL:https://www.med.unc.edu/compmed/event/clinical-data-literacy-series/2021-06-09/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2021/05/Clinical-Data-Literacy-Series.jpg
ORGANIZER;CN="PPMH":MAILTO:precisionmedicine@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210607T090000
DTEND;TZID=America/New_York:20210607T120000
DTSTAMP:20260414T115341
CREATED:20210505T164419Z
LAST-MODIFIED:20210505T164419Z
UID:10000289-1623056400-1623067200@www.med.unc.edu
SUMMARY:Clinical Data Literacy Series
DESCRIPTION:Recruitment email to send out with workshop application \nEmail subject line: Announcement – Research with EHR Data Workshop | June 7-11\, 2021 \n  \nClinical Data Literacy Series: Electronic Health Data Basics \nThe UNC Program for Precision Medicine in Health Care (PPMH)\, School of Medicine Clinical Research Support Office and NC Translational and Clinical Sciences Institute (TraCS) are organizing a hands-on virtual workshop that will introduce participants to   electronic health record (EHR) data. Content will include EHR data structure\, how to query EHR data and interpret the results and limitations of those queries\, how to deal with missing data\, and an introduction to the Carolina Data Warehouse. During the workshop\, participants will work with a de-identified EHR data set based on actual patient records. The workshop is aimed at UNC researchers\, students\, and clinicians who would like to use EHR data in research. \nThe workshop be taught via Zoom from 9am-12pm ET on Monday June 7\, Wednesday June 9\, and Friday June 11\, 2021. \nPoints to note: \n\nThe workshop is open to researchers with a current UNC-CH affiliation and onyen.\nSince the content will build upon sequential learning\, participants will be required to attend all sessions.\nA laptop or desktop computer with a second monitor is highly recommended.\nThe number of workshop participants will be limited to ensure that everyone receives adequate attention from the instructors and TAs.\nThere is no charge to attend\, but space is limited. We anticipate strong interest\, and we will from the pool of applicants.\n\n  \nApplication procedure: \nIf you are interested in attending the workshop\, fill out the application form by 9:00am Wednesday May 12\, 2021. Email precisionmedicine@med.unc.edu if you have any questions. \nWe will send out acceptance notifications the week of May 17. \n 
URL:https://www.med.unc.edu/compmed/event/clinical-data-literacy-series/2021-06-07/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2021/05/Clinical-Data-Literacy-Series.jpg
ORGANIZER;CN="PPMH":MAILTO:precisionmedicine@med.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210604T100000
DTEND;TZID=America/New_York:20210604T110000
DTSTAMP:20260414T115341
CREATED:20210616T195442Z
LAST-MODIFIED:20210616T195442Z
UID:10000293-1622800800-1622804400@www.med.unc.edu
SUMMARY:CompMed Research in Progress - No Meeting
DESCRIPTION:No meeting scheduled for today
URL:https://www.med.unc.edu/compmed/event/compmed-research-in-progress-no-meeting/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210521T100000
DTEND;TZID=America/New_York:20210521T230000
DTSTAMP:20260414T115341
CREATED:20201217T201851Z
LAST-MODIFIED:20210423T134941Z
UID:10000285-1621591200-1621638000@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Dr. Yuchen Yang / Li Qian Lab \nTalk Title: “Batch Effect Correction for Single-cell RNA-seq data via Supervised Mutual Nearest Neighbor Detection and Refinement”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-35/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/12/Yuchen-Yang.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210520T140000
DTEND;TZID=America/New_York:20210520T150000
DTSTAMP:20260414T115341
CREATED:20201110T191939Z
LAST-MODIFIED:20210430T170640Z
UID:10000211-1621519200-1621522800@www.med.unc.edu
SUMMARY:Computational Medicine Seminar
DESCRIPTION:Presenter: Muyinatu Bell\, PhD \n“Listening to the Sound of Light to Guide Surgeries” \nPhotoacoustic imaging offers “x-ray vision” to see beyond tool tips and underneath tissue during surgical procedures\, yet no ionizing x-rays are required. Instead\, optical fibers and acoustic receivers enable photoacoustic sensing of major structures – like blood vessels and nerves – that are otherwise hidden from view. The entire process is initiated by delivering laser pulses through optical fibers to illuminate regions of interest\, causing an acoustic response that is detectable with ultrasound transducers. Beamforming is then implemented to create a photoacoustic image. In this talk\, I will highlight novel light delivery systems\, new spatial coherence beamforming theory\, deep learning alternatives to beamforming\, and robotic integration methods\, each pioneered by the Photoacoustic & Ultrasonic Systems Engineering (PULSE) Lab to enable an exciting new frontier of photoacoustic-guided surgery. This new paradigm has the potential to eliminate the occurrence of major complications (e.g.\, excessive bleeding\, paralysis\, accidental patient death) during a wide range of delicate surgeries and procedures\, including neurosurgery\, cardiac catheter-based interventions\, liver surgery\, spinal fusion surgery\, hysterectomies\, biopsies\, and teleoperative robotic surgeries.
URL:https://www.med.unc.edu/compmed/event/computational-medicine-seminar-13/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Muyinatu-Bell.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210514T100000
DTEND;TZID=America/New_York:20210514T110000
DTSTAMP:20260414T115341
CREATED:20201217T201649Z
LAST-MODIFIED:20210430T171615Z
UID:10000284-1620986400-1620990000@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Boyce Griffith \nTalk Title: “Cardiac Modeling and Simulation Research in Progress”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-25/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2018/09/Boyce-Griffith.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210507T100000
DTEND;TZID=America/New_York:20210507T110000
DTSTAMP:20260414T115341
CREATED:20201217T201530Z
LAST-MODIFIED:20210423T135620Z
UID:10000283-1620381600-1620385200@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Natalie Stanley and Haidong Yi \nTalk Title: “Linking Multiple Sets of Cells Profiled with Mass Cytometry to External Variables”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-24/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/12/Stanley-and-Yi.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210422T120000
DTEND;TZID=America/New_York:20210422T173000
DTSTAMP:20260414T115341
CREATED:20210305T180858Z
LAST-MODIFIED:20210305T180858Z
UID:10000287-1619092800-1619112600@www.med.unc.edu
SUMMARY:Retreat
DESCRIPTION:Introductions \n12 NOON – 12:10 PM   Opening Statement \nCancer \n12:10 – 12:40 PM          Hoadley Lab \n12:40 – 1:10 PM             Palmer Lab \n1:10 – 1:40 PM               Purvis Lab \n1:40 – 1:50 PM               Break \nImmune \n1:50 – 2:20 PM                Vincent / Armistead Labs \n2:20 – 2:50 PM                Stanley Lab \n2:50 – 3:20 PM                Rubinsteyn Lab \n3:20 – 3:50 PM                Perou Lab \n3:50 – 4:00 PM                Break \nModeling \n4:00 – 4:30 PM                Rau Lab \n4:30 – 5:00 PM                Copos Lab \n5:00 – 5:30 PM                Elston Lab
URL:https://www.med.unc.edu/compmed/event/retreat/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210416T100000
DTEND;TZID=America/New_York:20210416T110000
DTSTAMP:20260414T115341
CREATED:20201110T193544Z
LAST-MODIFIED:20210423T134641Z
UID:10000280-1618567200-1618570800@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Andrew Hinton / Peter Mucha Lab \nTalk Title: “Simultaneous variable selection and group association testing in sparse high dimensional compositional data”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-33/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Andrew-Hinton.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210415T140000
DTEND;TZID=America/New_York:20210415T150000
DTSTAMP:20260414T115341
CREATED:20201110T191805Z
LAST-MODIFIED:20210423T134217Z
UID:10000209-1618495200-1618498800@www.med.unc.edu
SUMMARY:Computational Medicine Seminar
DESCRIPTION:Petter Brodin\, MD\, PhD\nAssociate Professor\, Human Systems Immunology\, Director of SciLifeLab Mass cytometry at Karolinska Institute\, Sweden \nTalk Title: “Human Systems Immunology” \n  \nPetter Brodin is a consultant in pediatric immunology combining clinical work at the Karolinska University Hospital\, with leading a research team of 15 members at the Science for Life Laboratory\, the Karolinska Institute. The team develops and applies system immunology approaches to study human immune system variation in health and disease and immune development early in life. The work of the group involves the elucidation of heritable and non-heritable factors that shape human immunity\, immune system development and adaptation early in life as well as a research program in clinical application of systems immunology. To enable these activities the group develops novel experimental and computational methods to more comprehensively and accurately monitoring immune systems in humans.
URL:https://www.med.unc.edu/compmed/event/computational-medicine-seminar-12/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Petter-Brodin.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210414T130000
DTEND;TZID=America/New_York:20210414T150000
DTSTAMP:20260414T115341
CREATED:20210310T175850Z
LAST-MODIFIED:20210310T175850Z
UID:10000288-1618405200-1618412400@www.med.unc.edu
SUMMARY:Machine Learning and Precision Analytics Mini-Symposium
DESCRIPTION:Join the UNC Program for Precision Medicine in Health Care (PPMH) for Machine Learning & Precision Analytics\, a free virtual mini-symposium from 1-3pm on Wednesday April 14. Presenters will explore information sources\, data science tools that use the information\, and the application of the resulting findings to health care. Another theme will be sources of bias in machine learning and how that bias can be minimized or eliminated. Participants will engage with presenters and each other around these topics. \n \nData-driven approaches towards linking kinotype with phenotype \nShawn Gomez\, PhD \nProfessor\, Pharmacology and UNC/NC State Joint Department of Biomedical Engineering \n  \nMachine learning for phenotyping in osteoarthritis \nAmanda Nelson\, MD \nAssociate Professor of Medicine\, Division of Rheumatology\, Allergy\, and Immunology \n  \nMachine learning in personalized cancer vaccine design \nAlex Rubinsteyn\, PhD \nAssistant Professor\, Computational Medicine and Lineberger Cancer Center \n  \nClick here to register. Contact precisionmedicine@med.unc.edu for more information.
URL:https://www.med.unc.edu/compmed/event/machine-learning-and-precision-analytics-mini-symposium/
LOCATION:NC
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210409T100000
DTEND;TZID=America/New_York:20210409T110000
DTSTAMP:20260414T115341
CREATED:20201110T193445Z
LAST-MODIFIED:20210423T133923Z
UID:10000279-1617962400-1617966000@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Calina Copos \nTalk Title: “Formation of actin networks — connecting across scales”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-32/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/12/Calina-Copos-Photo-scaled.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210402T100000
DTEND;TZID=America/New_York:20210402T110000
DTSTAMP:20260414T115341
CREATED:20201118T210535Z
LAST-MODIFIED:20210423T133832Z
UID:10000281-1617357600-1617361200@www.med.unc.edu
SUMMARY:Comp Med Research in Progress - No Meeting
DESCRIPTION:No Meeting Today
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-34/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210319T100000
DTEND;TZID=America/New_York:20210319T110000
DTSTAMP:20260414T115341
CREATED:20201110T193252Z
LAST-MODIFIED:20210422T142452Z
UID:10000278-1616148000-1616151600@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Yanguang (Carter) Cao Lab \nTalk Title: “modeling CAR-T cells kinetics in humans”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-31/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2019/01/Yanguang-Cao.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210318T140000
DTEND;TZID=America/New_York:20210318T150000
DTSTAMP:20260414T115341
CREATED:20201110T190421Z
LAST-MODIFIED:20210422T143646Z
UID:10000208-1616076000-1616079600@www.med.unc.edu
SUMMARY:Computational Medicine Seminar
DESCRIPTION:David Van Valen\, PhD \nAssistant Professor\, Division of Biology and Biological Engineering \nCalifornia Institute of Technology \nTalk Title:  “Single-cell biology in a software 2.0 world” \n  \nAbstract: \nMultiplexed imaging methods can measure the expression of dozens of proteins while preserving spatial information. While these methods open an exciting new window into the biology of human tissues\, interpreting the images they generate with single cell resolution remains a significant challenge. Current approaches to this problem in tissues rely on identifying cell nuclei\, which results in inaccurate estimates of cellular phenotype and morphology. In this work\, we overcome this limitation by combining multiplexed imaging’s ability to image nuclear and membrane markers with large-scale data annotation and deep learning. We describe the construction of TissueNet\, an image dataset containing more than one million paired whole-cell and nuclear annotations across eight tissue types and five imaging platforms. We also present Mesmer\, a single model trained on this dataset that can perform nuclear and whole cell segmentation with human-level accuracy – as judged by expert human annotators and a panel of pathologists – across tissue types and imaging platforms. We show that Mesmer accurately measures cell morphology in tissues\, opening up a new observable for quantifying cellular phenotypes in vivo. We make this model available to users of all backgrounds with both cloud-native software and on-premise software. Last\, we also describe ongoing work to develop a similar resource and models for dynamic live-cell imaging data.
URL:https://www.med.unc.edu/compmed/event/computational-medicine-seminar-11/
LOCATION:NC
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/David-Van-Valen.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210312T100000
DTEND;TZID=America/New_York:20210312T110000
DTSTAMP:20260414T115341
CREATED:20201110T193157Z
LAST-MODIFIED:20210422T142254Z
UID:10000227-1615543200-1615546800@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Jia (Elaine) Wen / Yun Li Lab \nTalk Title: “DeepGWAS to Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-30/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Jia-Wen.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210305T100000
DTEND;TZID=America/New_York:20210305T110000
DTSTAMP:20260414T115341
CREATED:20201110T193052Z
LAST-MODIFIED:20210422T142023Z
UID:10000225-1614938400-1614942000@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Mauro Calabrese lab \nTalk Title: “k-mer-based approaches to identify regulatory function in long noncoding RNAs”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-29/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2018/09/Mauro-Calabrese.jpeg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210219T100000
DTEND;TZID=America/New_York:20210219T110000
DTSTAMP:20260414T115341
CREATED:20201110T192655Z
LAST-MODIFIED:20210121T190038Z
UID:10000221-1613728800-1613732400@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Hillary Heiling / Naim Rashid Lab \nTalk Title: “Estimating Cell Type Composition using Isoform Expression One Gene at a Time”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-27/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Hillary-Heiling-1.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210218T140000
DTEND;TZID=America/New_York:20210218T150000
DTSTAMP:20260414T115341
CREATED:20201110T190319Z
LAST-MODIFIED:20210205T161324Z
UID:10000277-1613656800-1613660400@www.med.unc.edu
SUMMARY:Computational Medicine Seminar
DESCRIPTION:Presenter: Kevin Janes\, PhD \nTalk Title: “Complete kinetic modeling of an RNA pathogen” \nComplete kinetic models are pervasive in chemistry but lacking in biological systems. We encoded the complete kinetics of infection for coxsackievirus B3 (CVB3)\, a compact and fast-acting RNA virus. The kinetics are built from detailed modules for viral binding–delivery\, translation–replication\, and encapsidation. Specific module activities are dampened by the type I interferon response to viral double-stranded RNAs (dsRNAs)\, which is itself disrupted by viral proteinases. The validated kinetics uncovered that cleavability of the dsRNA transducer mitochondrial antiviral signaling protein (MAVS) becomes a stronger determinant of viral outcomes when cells receive supplemental interferon after infection. Cleavability is naturally altered in humans by a common MAVS polymorphism\, which removes a proteinase-targeted site but paradoxically elevates CVB3 infectivity. These observations are reconciled with a simple nonlinear model of MAVS regulation. Modeling complete kinetics is an attainable goal for small\, rapidly infecting viruses and perhaps viral pathogens more broadly. \n\nJanes\, Kevin A.
URL:https://www.med.unc.edu/compmed/event/computational-medicine-seminar-10/
LOCATION:NC
CATEGORIES:Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/KevinJanes_headshot.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210212T100000
DTEND;TZID=America/New_York:20210212T110000
DTSTAMP:20260414T115341
CREATED:20201110T192943Z
LAST-MODIFIED:20210121T211019Z
UID:10000223-1613124000-1613127600@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Wancen Wu / Michael Love Lab \nTalk Title: “Differential allelic imbalance across groups of cells”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-28/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Wancen-Mu.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210205T100000
DTEND;TZID=America/New_York:20210205T110000
DTSTAMP:20260414T115341
CREATED:20201110T192553Z
LAST-MODIFIED:20210121T183738Z
UID:10000219-1612519200-1612522800@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Hannah Janine Perrin / Karen Mohlke Lab \nTalk Title: “Chromatin accessibility during adipocyte differentiation identifies context-dependent effects for cardiometabolic traits”
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-26/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/11/Hannah-Janine-Perrin.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210129T100000
DTEND;TZID=America/New_York:20210129T110000
DTSTAMP:20260414T115341
CREATED:20201223T153220Z
LAST-MODIFIED:20210121T175640Z
UID:10000286-1611914400-1611918000@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Zhengwu Zhang \nTalk Title: “Recent progress on analyzing brain imaging data” \nAbstract:  This is a brief talk on our recent progress on acquiring\, representing\, and analyzing brain imaging data. I’d like to briefly introduce brain connectomes and formulate several interesting statistical problems to illustrate my research interests. Briefly\, you will see shape analysis\, optimal experimental design\, connectome extraction and representation\, and graph-data analysis using advanced machine learning techniques in the talk. Each topic will be brief\, and I will mainly discuss why and how we formulate these problems.
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-36/
LOCATION:NC
ATTACH;FMTTYPE=image/jpeg:https://www.med.unc.edu/compmed/wp-content/uploads/sites/852/2020/12/Zhengwu-Zhang.jpg
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210121T140000
DTEND;TZID=America/New_York:20210121T150000
DTSTAMP:20260414T115341
CREATED:20201110T185614Z
LAST-MODIFIED:20210121T175414Z
UID:10000276-1611237600-1611241200@www.med.unc.edu
SUMMARY:Computational Medicine Seminar - Canceled
DESCRIPTION:
URL:https://www.med.unc.edu/compmed/event/computational-medicine-seminar-9/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210115T100000
DTEND;TZID=America/New_York:20210115T110000
DTSTAMP:20260414T115341
CREATED:20201110T192225Z
LAST-MODIFIED:20201217T200058Z
UID:10000216-1610704800-1610708400@www.med.unc.edu
SUMMARY:Comp Med Research in Progress - Canceled
DESCRIPTION:No January Meeting
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-23-2021-01-08/2021-01-15/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210108T100000
DTEND;TZID=America/New_York:20210108T110000
DTSTAMP:20260414T115341
CREATED:20201110T192225Z
LAST-MODIFIED:20201217T200058Z
UID:10000215-1610100000-1610103600@www.med.unc.edu
SUMMARY:Comp Med Research in Progress - Canceled
DESCRIPTION:No January Meeting
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-23-2021-01-08/2021-01-08/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210101T100000
DTEND;TZID=America/New_York:20210101T110000
DTSTAMP:20260414T115341
CREATED:20201110T192225Z
LAST-MODIFIED:20201217T195837Z
UID:10000213-1609495200-1609498800@www.med.unc.edu
SUMMARY:Comp Med Research in Progress - Canceled
DESCRIPTION:No January Meetings
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-23/
LOCATION:NC
ORGANIZER;CN="Victoria Doyle":MAILTO:vdoyle@email.unc.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201218T100000
DTEND;TZID=America/New_York:20201218T110000
DTSTAMP:20260414T115341
CREATED:20200624T193736Z
LAST-MODIFIED:20201124T192011Z
UID:10000251-1608285600-1608289200@www.med.unc.edu
SUMMARY:Comp Med Research in Progress
DESCRIPTION:Presenter: Markia Smith / Hoadley Lab \nTalk Title: “Mutational signature analysis in breast cancer” \n 
URL:https://www.med.unc.edu/compmed/event/comp-med-research-in-progress-12/
LOCATION:NC
END:VEVENT
END:VCALENDAR