Canceled - CompMed Research in Progress
2023-02-10 10:00 - 11:00 (America/New_York) | NC

Faculty Candidate Seminar
2023-02-14 16:00 - 17:00 | Bioinformatics Building, Room 1131, 130 Mason Farm Rd, Chapel Hill, NC, 27514, United States
Talk Title: Machine Learning the Rules od Antibody-Virus Interactions
Tal did his PhD at Caltech with Rob Phillips, whose lab specializes in developing models that don’t just fit data, but provide deep insights into the underlying mechanisms. In his postdoc, Tal shifted lanes into immunology, joining Jesse Bloom’s lab at the Fred Hutch Cancer Center which studies the antibody response against viruses such as influenza, HIV, and SARS-CoV-2. Tal is a Damon Runyon Quantitative Biology Fellow, and today we will hear about one of his multidisciplinary research projects that combines concepts from physics, math, biology, and computer science to help us understand and augment our antibody response against viruses.
Abstract for advertising talk: Immunology is undergoing a paradigm shift where the objective has expanded from creating a stopgap vaccine against a currently-circulating virus to developing a universal vaccine that confers lifelong protection. My research uses biophysical modeling and machine learning to probe how the antibody response changes with each viral exposure, with the ultimate goals of making the antibody response programmable and guiding it to a maximally-protective configuration. My lab will initially build off my expertise with influenza, but future efforts will generalize these methods to other viruses such as HIV-1 and SARS-CoV-2 that are of interest to public health.

Canceled - CompMed Research in Progress
2023-02-17 10:00 - 11:00 | NC
Holiday weekend and Monday is Mental Health Day.
Enjoy your weekend

CompMed Seminar
2023-02-28 14:00 - 15:00 | Bioinformatics Building, Room 1131, 130 Mason Farm Rd, Chapel Hill, NC, 27514, United States
Presenter: Trachette Jackson, PhD
University of Michigan
Date February 28, 2023
Talk Title “Multiscale Models for Understanding Tumor-Immune Dynamics and Optimizing Immune and Targeted Therapy Schedules”
Trachette Jackson is a professor in the Department of Mathematics in the College of Literature, Science, and the Arts and Assistant Vice President for Research – DEI Initiatives at the University of Michigan. Motivated by addressing critical challenges associated with cancer therapeutics, developing multiscale mathematical models is the aim of much of Dr. Jackson’s research. She designs these models to optimize the use of anticancer agents that specifically target active molecular pathways that cancer cells use to promote their growth and survival. Jackson is an award-winning educator and scholar who has received honors for her accomplishments in both areas. In 2003, she became the second African American woman to receive the prestigious Alfred P. Sloan Research Award in Mathematics; in 2005, she received the James S. McDonnell 21st Century Scientist Award; in 2008 Diverse Magazine honored her as one of the year’s Emerging Scholars. In 2010 she received the Blackwell-Tapia Prize, which biannually recognizes a mathematician for both their research achievements and for their contributions to addressing diversity in mathematics and in 2012 she was elected to the inaugural class of Simon’s Foundation Fellows, an honor featured in the NY Times. More recently, Dr. Jackson was voted into the inaugural class of Association for Women in Mathematics (AWM) Fellows and the 2021 class of the Society of Industrial and Applied Mathematics (SIAM) Fellows, becoming the first African American to have this honor.

CompMed Research in Progress
2023-03-03 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Assistant Professor Susana Garcia Recio
Talk Title: Multiomics analysis of matched primary and metastatic breast tumors from the AURIRA US Network

Research in Progress
2023-03-10 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Caitlin Rose Lahue
Talk Title: Differential Methylation in Isoproterenol Induced Heart Failure

No CompMed Seminar - Spring Break
2023-03-16 14:00 - 15:00 | NC

No Meeting - Research in Progress
2023-03-17 10:00 - 11:00 | NC
Enjoy Spring Break

BRC Spring Seminar - Dr. Karl Desch
2023-03-17 11:00 - 12:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Together with Dr. Erica Sparkenbaugh in the Blood Research Center, Karin Leiderman, PhD is hosting a seminar speaker for the BRC Spring Seminar series. They invited Dr. Karl Desch from the University of Michigan on March 17th, at 11:00 am. His talk is titled: “Using human genetic variation to explore mechanisms of hemostasis and thrombosis.”

Mini-Symposium - Precision Nutrition: Connections Between Food, Environment, & Health
2023-03-22 08:00 - 16:00 | NC
Join the UNC Program for Precision Medicine in Health Care (PPMH) for Precision Nutrition: Connections Between Food, Environment, & Health, a free virtual mini-symposium from 2:00-4:00pm on Wednesday March 22, 2023. Precision nutrition is an emerging personalized approach to nutrition that takes into account an individual’s unique dietary needs, lifestyle factors, and genetic makeup. This approach recognizes the intricate relationship between diet, environment, and health, acknowledging that what we eat and how we live can significantly impact our wellbeing.

Presentations:
Blending Precision Nutrition and Precision Public Health Approaches: “Neighborhood-omics”
Alice Ammerman, DrPH
Mildred Kaufman Distinguished Professor, Department of Nutrition, School of Public Health
Director, Center for Health Promotion & Disease Prevention, School of Medicine

Metabolic Individuality and Nutrition for Precision Health
Susan Sumner, PhD
Professor, Department of Nutrition, School of Public Health

How to Use Precision Nutrition in Current Clinical Practice
Martin Kohlmeier, MD, PhD
Professor, Department of Nutrition, School of Public Health

Click here for more information.
Click here to register.
Contact precisionmedicine@med.unc.edu with any questions.

NO Research in Progress
2023-04-07 10:00 - 11:00 | NC
University is closed
Enjoy the long weekend

Research in Progress
2023-04-14 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Amy Pomeroy / Palmer Lab
Talk Title: Accurate Prediction of Lymphoma Clinical Trials

CompMed Seminar James Blachly
2023-04-20 14:00 - 15:00 | Lineberger Pagano Conference Room, 450 West Drive, Chapel Hill, 27599, United States
Presenter: James Blachly
The Ohio State University Comprehensive Cancer Center
Talk Title: Real-time Leukemia Diagnostics

Research in Progress
2023-04-21 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Mikayla Feldbauer / Hoadley Lab
Talk Title: Impact of FFPE Preservation on RNA Sequencing Analyses

CompMed Research in Progress
2023-05-05 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Keith Alexander Breau, Elston Lab
Talk Title: Modeling the Wnt planar cell polarity complex: coordinating cell polarity during collective migration

UNC Spring Fling
2023-05-05 11:30 - 12:00 | UNC Student Recreation Center
Join the UNC Campus Recreation staff for the annual SPRING FLING. The Spring Fling is a 2.5 mile fun run or 1.25 mile walk open to all UNC-Chapel Hill faculty and staff. In previous years, over 300 participants have completed the course individually or as part of a departmental team. The event promotes physical activity, health and well-being and provides employees with the opportunity to contribute to the local food bank by making a canned food donation. In addition, pet donations will be given to the Orange County Animal Shelter. Free refreshments will be provided for participants after the event. This event is rain or shine!
Date: Friday, May 5, 2023
Check in 11:30AM- noon
Run/Walk Time: 12:15PM
Location: in front of the Student Recreation Center
Prizes: Awards will be given to the team with the most creative costumes celebrating the SPRING season and the most spirited team.
Donations: Collections will be made for two charities this season: Non-perishable food items will be donated to a local food bank. Non-perishable pet items will be donated to the local animal shelters (food, old blankets, leashes, bowls, collars, etc. are all welcome). Those making a donation to either cause will be eligible for a special drawing.

CompMed Research in Progress
2023-05-12 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Elizabeth Claire Brunk, PhD
Talk Title: Extrachromosomal DNA create new gene neighborhoods to increase cell population fitness

Computational Medicine Seminar
2023-05-18 14:00 - 15:00 | NC
Presenter: Dr. Sara Mostafavi
Assistant Professor, Paul Allen School of Computer Science and Engineering
University of Washington, Seattle
Department of Statistics and Medical Genetics
Talk Title: “Deep Learning of Immune Cell Differentiation”

CompMed Research in Progress
2023-05-19 10:00 - 11:00 | Mary Ellen Jones 3112, 116 Manning Drive, Chapel Hill, NC, 27514
Presenter: Alec Plotkin
Talk Title: Trajectory Inference to Identify Drivers of CD8 T-cell Responses to Acute Infection

CompMed Research in Progress
2023-09-01 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter Dhuvi Kartikeyan (Rubinsteyn Lab)
Talk Title: Conditional Generation of Diverse TCR:pMHC Sequence Pairs Using Deep Neural Networks

CompMed Research in Progress
2023-09-08 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Emma Crawford (Stanley Lab)
Talk Title: Learning How to Modulate and Tune the Immune System

CompMed Research in Progress
2023-09-15 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Jamie Madrigal
Talk Title: Modeling Enzyme Kinetics in the Presence of Lipids

CompMed Seminar
2023-09-28 14:00 - 15:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Pratip Chattopadhyay, Ph.D.
CEO and Founder of Talon Biomarkers
Talk Title: ” From Full Spectrum Flow Cytometry to Fully Interpretable Biology”

CompMed Research in Progress
2023-10-06 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Sarah Patterson
Talk title: “Curative Chemotherapy Regimens in Germ Cell Tumors”

CompMed Research in Progress
2023-10-13 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Jinan Wang, PhD
Talk Title: “Ligand Gaussian Accelerated Molecular Dynamics 3 (LiGaMD3): Improved Calculations of Ligand and Peptide Binding Kinetics”

CompMed Research in Progress
2023-11-03 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Yixiang Qu (Di Wu Lab)
Talk Title: BGOB: A new deep learning method for microbiome time series analysis

CompMed Research in Progress
2023-11-10 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Garrett Sessions (Purvis Lab)
Talk Title: Tracing the Temporal Dynamics of Senescence Induction

CompMed Research in Progress
2023-11-17 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Sana Akhter (Miao Lab)
Talk Title: “Mechanism of ligand binding to theophylline RNA aptamer”

CompMed Research in Progress
2023-12-01 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Tarek Zikry (Purvis Lab)
Talk Title: Mechanism of ligand binding to theophylline RNA aptamer

CompMed Research in Progress
2023-12-08 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Brian Gural (Rau Lab)
Talk Title: “Defining Cardiac Cellular Compositional Changes by Deconvolution in a Mouse Model of Heart Failure”
