Seminar
2024-02-15 14:00 - 15:00 (America/New_York) | Bioinformatics Building, Room 1131, 130 Mason Farm Rd, Chapel Hill, NC, 27514, United States
Presenter: Michael K. Gilson, Ph.D.
Distinguished Professor
Skaggs School of Pharmacy and Pharmaceutical Sciences,
University of California San Diego, LaJolla, CA
Hosted by: Yinglong Miao, Ph.D.
Talk Title: “Mining Minimal Affinity Calculations and the BindingDB Database, Tools for Drug Discovery”
About the speaker:

Grew up in New York City.
A.B. Bioengineering at Harvard College, 1981
MD-PHD program at Columbia College of Physicians and Surgeons in New York City, 1981-1989. PhD in Biochemistry and Molecular Biophysics.
Part 1 (inpatient) of internal medicine residency (Clinical Investigator Pathway) at Stanford University Hospital, Palo Alto, CA, 1989-1991
Part 2 (outpatient and research) of Internal medicine residence at Baylor College of Medicine, Houston, TX 1991-1993.
Postdoctoral fellowship as Howard Hughes Physician Medical Fellow at the University of Houston, with Prof. J Andrew McCammon, 1991-1994
CARB Fellow and Assistant Professor to Professor, Center for Advanced Research in Biotechnology (CARB), Rockville, MD, 1994-2010.
Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, 2010-present.

“My lab has focused on the development of the physical chemistry theory of non-covalent binding and methods and software for computer-aided drug design. We also originated and continue to run BindingDB, a large database of measured protein-small molecule binding data used by researchers worldwide. Recently, we have worked to improve the potential functions used in molecular simulations, have done theoretical work on the mechanisms of molecular motors, and have worked on the use of artificial intelligence in drug discovery”

CompMed Research in Progress
2024-02-16 10:00 - 11:00 | Mary Ellen Jones 3116, 116 Manning Drive, Chapel Hill, NC, 27599, United States
Presenter: Guorong Wu (PI)
Talk title: Understand novel mechanism using machine learning techniques
