Single Cell Proteogenomics presentation
2017-01-24 09:00 - 11:00 (America/New_York)
Please join us for this free presentation.Topics covered will include:
• How FACS sorting isolates optimal single cells for genomic analysis• BD Molecular Indexing technology and how it eliminates PCR bias in mRNAseq• FACS sorting to sequencing: BD Precise™ 96-well assay and workflow for WTA and Custom Transcript mRNAseq• BD Resolve ™ platform for high throughput single-cell analysis (100’s-10,000’s of single cells for mRNAseq)
Refreshments will be served

Embracing Unique Next-Gen Sequencing Technologies
2017-02-23 12:30 - 14:00
Join us for this free seminar.Lunch provided with RSVP to Katherine T. Berger
Seminar Summaries:
genoTYPER-NEXT
Traditional screening methods for on/off target effects from genome editing experiments may be time consuming, ineffective, and/or expensive. GENEWIZ has developed a method to alleviate all of these pain points, termed genoTYPER-NEXT. This proprietary method includes interactive data exploration to promote in-depth, scalable, clone analysis.
Metagenomics
Shotgun genome sequencing, coupled with GENEWIZ’s proprietary bioinformatics pipeline, allows researchers to visualize and interact with their data for species identification and functional significance. GENEWIZ also offers custom targeted 16S sequencing using their optimized MetaVx™ service and is developing a full length 16S assay for the PacBio Sequel.
Additional Next-Gen Sequencing Technologies

GENEWIZ has recently released ultra-long read sequencing on the PacBio Sequel for WGS.
The 10X Genomics Chromium provides true single-cell RNA-seq library preparation with compatibility for Illumina HiSeq sequencing.

Speaker:
Jessica Oates, Technical Application Scientist at GENEWIZ in the Next-Generation Sequencing area, providing project consultation for the HTSF NGS services.

Single Cell and High Throughput Genomics core services at UNC
2017-03-02 16:30 - 17:30
Presented by Scott T. Magness, Ph.D., Associate Professor, UNC/NCSU joint departments of Biomedical Engineering
Dr. Magness’ research program focuses on genetic regulation of intestinal stem cell maintenance and differentiation and development of novel approaches to single-cell biology. He is the founder and director of CGIBD’s Advanced Analytics Core, which offers single-cell and high-throughput genomics services. His talk will focus on the state of single cell genomics platforms and the services offered by the AA core.
Conference will also be streamed live, visit the CGIBD website events section for link

Genome Editing and Stem Cell Engineering for Disease Modeling
2017-03-08 12:00 - 13:00
Join us for this seminar presented by Dr. Adriana Beltran, Director of the Human Pluripotent Stem Cell Core.Past, present, and prospective users are invited to learn about and provide feedback on the core services.Pizza provided.

UNC Core Facilities Show & Tell
2017-03-21 11:00 - 14:00
35 UNC Cores will be on hand with displays and information about their core services.
Lunch provided.

CHANL 9th Annual Scientific Art Show
2017-04-24 12:30 - 14:30
View the entries in the Chapel Hill Analytical and Nanofabrication Lab’s 9th annual scientific art competition, and vote for your favorites.Seminar at 1:20 pm, Chapman Hall room 201, on “The Science in Art: Bio-Medical Imaginging Techniques Applied to the Non-Invasive Investigation of Cultural Heritage” by Bill Brown, Chief Conservator from the NC Museum of Art.
Lunch included
Awards will be announced at the end of the seminar.

Seminar: New Tools for the Emerging Field of Single-Cell Analysis
2017-05-19 10:00 - 12:00
As the use of NGS advances in clinical and applied spaces, the parallelprocessing of single cells from precious patient samples at highthroughputs will be critical. With increasing demand for single-cell NGSanalyses, several platforms have emerged based on microfluidics, such as droplet-based and multisample nanodispensing technologies. The ICELL8™ Single-Cell System enables researchers to look at hundreds of cells in a heterogeneous cell population without common microfluidic cell-size constraints, and the imaging limitations of the droplet-based systems, thereby reducing sample-handling artifacts.
Speaker: John F. Sojda III, PhD, with Takara Bio USA, Inc.
Please RSVP to Katherine Berger: kberger@email.unc.edu
Coffee provided by Department of Genetics

Center for Structural Biology Core and Vendor Show
2017-06-08 11:00 - 13:30
Join us to learn what these UNC CSB core facilitiescan do for your research and engage with over 30vendors showcasing their latest products and service.
Lunch included

Genomics Seminar
2017-07-20 11:30 - 13:30
The High Throughput Sequencing Facility and the Department of Genetics present a genomics seminar with Bionano:
The majority of many complex genomes are made up of repetitive and regulatory elements. Short read sequencing or exome sequence strategies, while very powerful, are unable to map these highly repetitive sequences. As a result, critical information about the genome may be missed when analysis relies on NGS technologies alone.
Bionano Genomics’ platform for whole genome mapping allows for extremely long read data, resulting in unmatched sensitivity and specificity to detect large structural variation. Our de novo maps can resolve complex repetitive regions, identify Copy Number Variations, and elucidate genome-wide large structural variation like balanced/unbalanced translocations, inversions, and large indels.
Specific examples will be presented of how Bionano’s platform is helping provide a molecular diagnosis for patients with Duchenne Muscular Dystrophy, identify potential causative variants for patients with undiagnosed genetic disorders, and how it has been applied to discover large, potentially oncogenic genomic rearrangements in prostate cancer and leukemia that were missed by NGS.
Speaker: Sven Bockland, PhD, Sr. Application Specialist, Bionano
Lunch provided with RSVP

BBL Training Workshop: Observational Methods, Physiology, and Salivary Bioscience
2017-08-07 08:00 - 2017-08-08 16:30
Have you seen the calls for biobehavioral methods from funding agencies like the National Institutes of Health? Have you considered using these methods in your research but wondered how to get started?
The UNC School of Nursing Biobehavioral Laboratory will present a training program on observational and physiologic research methods and their integration on Monday, August 7th followed by an overview of salivary bioscience on Tuesday, August 8th.For those interested in mentored in-laboratory training in collecting and analyzing their own salivary cortisol samples, a Hands-on Salivary Assay Lab in our Salimetrics Center of Excellence designated lab (limited to 4 participants; 2:1 student/instructor ratio) will be offered on Wednesday, August 9th. This lab is a full day experience.

FASEB BioArt Scientific Image and Video Competition
2017-08-31 08:00 - 17:00
About BioArt
Through the BioArt competition, hte Federation of American Societies for Experimental Biology (FASEB) aims to share the beauty and breadth of biological research with the public. Contestants include investigators, contractors, or trainees with current or past research funding from a US federal agency and members of FASEB societies.

Seminar: Introduction to Mass Spectrometry Core Facilities at UNC
2017-09-14 13:00 - 14:00
Mass Spectrometry (MS) is a powerful analytical technique used to measure the mass of molecules. Data generated by MS enhances our understanding of the physical, chemical, or biological properties of compounds. Learn about the MS core facility resources available to you on campus. Presentations from Laura Herring, PhD, Director of the Michael Hooker Proteomics Center, Wanda Bodnar, PhD, Director of the Biomarker Mass Spectrometry Core Facility, and Brandie Ehrmann, PhD, Director of the Department of Chemistry Mass Spectrometry Laboratory.

Genomics Seminar: The Next Era in NGS Sequencing: NovaSeq Systems:
2018-03-13 11:15 - 12:15
The High Throughput Sequencing Facility presents a genomics seminar:
The NovaSeq Systems unleash groundbreaking innovations that leverage illumina’s proven technology. Now you can get scalable throughput and flexibility for virtually any sequencing method, genome and scale of project. Learn more about how your applications such as RNASeq, WGS, WES, Small RNA, and ATAC-Seq will benefit from reduced sequencing costs and fast turn-around times from both the new NovaSeq platform as well as our latest library prep portfolio products including, Nextera Flex and AmpliSeq for Illumina.
Come learn about this new instrumentation now available in the HTSF!
Speaker: Matt Angel, Sr. Sequencing Specialist
Light refreshments provided by Dept. of Genetics RSVP by March 9 to: Erin Wallace: wallacee@live.unc.edu

Imaris Imaging and Analysis Workshop
2018-05-22 09:00 - 2018-05-23 17:00
Imaris is a powerful tool to visualize and analyze 3D data, and the workshop will cover many aspects of basic and advanced operation of the software. There will also be some time for one-on-one sessions with your data. The ideal target for this workshop are researchers who need to visualize and analyze 3D data, but do not have much experience with the software. Attendance will cost $50.
To register for this event, please fill out the information in the following link: https://goo.gl/forms/zX3BiWYNq2XVtos53
If the workshop is over-subscribed we will first screen to prioritize users with an immediate scientific need for Imaris, and then, if necessary, will hold a lottery. We plan to notify all applicants on May 1st regarding their final registration status.
Agenda

Microfluidics talk
2018-08-21 11:00 - 13:00
The Advanced Analytics Core is hosting a talk next Tuesday, August 21st from 11am-1pm in the Pagano conference room. The presenter, Dr. Katy Richards-Hrdlicka, will be discussing the use of microfluidics in genomics research, with special emphasis on cancer-related applications. Please see the attached flier for more details, or click here to pre-register; first 50 registrants receive box lunch.

Milliplex: High Throughput Biomarker and Immunoassays
2018-09-25 13:00 - 14:00
Learn about the xMAP-based multiplex immunoassay technology offered through the Advanced Analytics Core. The speaker is James Alin, an FAS with MilliporeSigma.Lunch included
MilliporeSigma will also be hosting a vendor show covering a broader range of their products from 10am – 2pm in the lobby of MBRB (first and second floor).

BRIC SAI Core Seminar: Hands-Free Preclinical Ultrasound Imaging
2018-10-02 13:00 - 14:00
The BRIC Small Animal Imaging Core presents a free seminar: Hands-Free Preclinical Ultrasound Imaging
A revolutionary preclinical imaging platform has been developed by SonoVol, inc. This powerful new device can support researchers in several disease applications. This powerful new device can support researchers in several disease applications.
Speaker: Dr. Ryan Gessmer, SonoVol, Ic.

CyTOF Research Day
2018-10-22 10:15 - 13:30
Schedule:
10:15 -10:45 AM – “Taking the First Steps of Mass Cytometry”
Dan Frederick, PhD, Field Application Specialist I, Fluidigm
10:45 -11:45 AM – “Learning in vivo: How Data Science and Cytomics Are Connecting Cell Biology and Medicine”
Jonathan Irish, Assistant Professor, Vanderbilt University

11:45 – 12:00 PM – Grab a Lunch

12:00 – 12:30 PM – “Immune profiling of Chlamydia trachomatis infected women”
Avinash Kollipara, Post-doctoral Research Associate, Department of Pediatrics and Microbiology & Immunology, UNC

12:30 – 1:30 PM – “Deep Immune Profiling using the Maxpar Human Immune Monitoring Panel Kit with Mass Cytometry”
Bruce Bagwell, President, Verity Software House

If you plan to stay for lunch, please register here:
https://www.eventbrite.com/e/mass-cytometry-research-day-at-unc-registration-50766371584

BRIC Small Animal Imaging Facility Seminar
2018-11-06 13:00 - 14:00
Multispectral Optoacoustic Tomography (MSOT): Recent Applications and Technological Developments
Optoacoustics is an emerging field of biomedical imaging. Multispectral Optoacoustic Tomography (MSOT) is a powerful molecular imaging technology which provides optical contrast at depth. It provides the capacity to separate endogenous chromophores such as oxy-/deoxy-haemoglobin, melanin, lipids and collagen, as well as extrinsically administered agents including nanoparticles and fluorescent dyes. With a focus on new developments in the field, this presentation will cover both technology as well as research driven applications. Areas of research will include cancer, anatomical and functional neurology, inflammation , kinetics, nanotechnology and probe development.
Speaker: Clinton Hupple, Ph.D, SonoVol, Inc.
coffee and snacks will be served

Neuroscience Center Seminar:
2018-11-08 12:30 - 13:30
Let the Microscopy and Bioinformatics Cores Improve Your Life: New Tools and Approaches to Enhance Your Capabilities and Yield new Discoveries
Presenters: Michelle Itano, Neuroscience Center Microscopy Core and Jeremy Simon and Travis Ptacek from the Neuroscience Center Bioinformatics Core

Seminar: Chromium Controller Single Cell Application and Protocol Review
2019-02-06 09:00 - 10:30 | Genetic Medicine Building (GMB), Room 5007
This is an opportunity to learn about the 10x Chromium Single Cell instrument and ask any questions.

Hooker Imaging Core (HIC) Seminar and Hands-On Training
2019-03-26 10:00 - 16:45 | Taylor Hall
Simplifying High Contect Analysis for Cell Biology and Drug Development
The Hooker Imaging Core (HIC) presents a morning seminar and afternoon hands-on session with speakers Daniel Collins and Lisa Kirouac from GE Healthcare Lifesciences Division, Cell Analysis.

Lunch will be provided following the seminar, registration required:Robert Currin

Seminar: The Antibody Crisis: Leveraging machine learning for evidence-based antibody search
2019-04-09 11:00 - 12:30
The“reproducibility crisis” has generated much attention in the research community over the past years. While the issue is multifaceted at its core, rogue antibodies have been identified as one of the major culprits.

To ensure scientists can find antibodies that have been proven to work repeatedly by peers, we developed an open-access resource that uses a machine learning algorithm to screen the literature and identify which and how antibodies have been cited. The resulting peer-reviewed data are searchable by protein targets or product identifier, and are filterable by experimental contexts as cited in papers, including technique, tissue, cell line, to help users pinpoint antibodies that have been published under experimental conditions matching their study interest.
Freely accessible resource for UNC and affiliated scientists at https://www.benchsci.com

Please RSVP for free pizza at the end of the talk: https://forms.gle/zvHZzBANjbLtX7io9

Human Pluripotent Cells: Products for Your Research
2019-04-11 12:00 - 13:00
The Human Pluripotent Cell Core presents a lunch and learn seminar:
Cell Quality, Gene Editing and Differentiation
Speaker: Howon Kim, Field Applications Scientist, STEMCELL TECHNOLOGIES
Lunch provided by SOM Office of Research
RSVP required: amma.semenya@stemcell.com

2019 Triangle Imaging Symposium at UNC BRIC
2019-04-24 08:30 - 16:00 | BioInformatics Building Room 1131
The 2019 Triangle Imaging Symposium at UNC BRIC will feature lectures by speakers from Johns Hopkins, UNC, Duke, NCSU and Wake Forest University and is open to the entire scientific community. This year, a broad spectrum of topics will be covered, from molecular and cellular imaging with MRI, to simple and cheap hyper polarization techniques that can boost MR sensitivity by several orders of magnitude, to computational tools for large-scale brain network, to advanced ultrasound methodologies for tissue characterization.
The Symposium also includes a Poster Session with presentations given by students, trainees, residents, and faculty to highlight imaging research projects within and outside UNC.
Free.
Register

HTSF Presents: Resolving Tumor Heterogeneity and Clonal Evolution with Single-Cell DNA Analysis
2019-04-24 11:30 - 13:00 | Bondurant Hall Room 2035
Current bulk sequencing methods are inadequate to fully characterize cancer. Targeted single-cell DNA analysis resolves tumor heterogeneity, which has critical implications in understanding clonal evolution and the acquisition of therapeutic resistance.
Join us to learn about the applications of the Tapestri Platform
Speaker: Shawn Clouthier, Senior Field Applications Scientist, Mission Bio
Lunch/Refreshments provided by the Department of Genetics, RSVP required: wallacee@live.unc.edu

BioBehavioral Lab (BBL) Workshop: Integrating Salivary Bioscience
2019-04-25 09:00 - 11:30 | Carrington Hall, Room 207
The BBL presents a salivary markers workshop:
Integrating Salivary Bioscience into behavioral, Developmental and Health Science Research

No cost but registration is required:
https://salimetrics.com/workshops-training/#pre-register-area

HTSF Presents: RNA-Seq Experiment Pipeline - Lunch and Learn
2019-04-25 12:00 - 13:00 | MacNider Hall, Room 322
Lexogen Inc. has developed a complete line of reagent kits for working with the transcriptome to make
your life easier. From RNA extraction, rRNA depletion and mRNA enrichment, to library prep kits for
small RNA, whole transcriptome and expression profiling. We also introduced a Metabolic RNA-Seq kit
for measuring nascent RNA levels in cells, globin blockers for working with blood samples and spikein
RNA variant controls for experimental quality control. Seminar will include a technical overview of
these products and describe how to make libraries without fragmenting your RNA to get unparalleled
strand specificity. We will also show you how to make expression profiling easy and affordable.
Speaker: Jeff Hudson, Lexogen, Inc.
Lunch Provided by the Department of Genetics
RSVP required for lunch: wallacee@live.unc.edu

HTSF Presents: Simplify Your NGS Workflow from Sample to Insight
2019-05-01 09:30 - 15:30
High Throughput Sequencing Facility hosts
A QIAGEN CLC Workshop: QIAGEN’s complete solutions for RNA-seq, microbiome and metagenomics
Agenda:
09:30 – 10:15: Introduction to QIAGEN bioinformatics solutions
10:30 – 12:00: RNA-seq data analysis
12:00 – 01:00: Lunch and learn: “A Systemic Approach to Microbiome and Metagenomic Project Design”
01:00 – 02:15: Microbiome analysis: 16s/shotgun sequencing
02:30 – 3:30: Genome and Metagenome assembly
Lunch/Refreshments provided by the Department of Genetics
RSVP required
RSVP to: wallacee@live.unc.edu

Proteomics Center presents a one-day symposium: Innovations in Mass Spectrometry
2019-05-14 10:00 - 14:00 | Medical Biomolecular Research Building (MBRB) Room G202
Innovations in Mass Spectrometry that Excel Life Science Research
Register today for this free, one-day symposium that will highlight the latest developments in MALDI-TOF mass
spectrometry imaging and trapped ion mobility spectrometry (TIMS) instrumentation designed to advance life science
research.

Please click to register so we can get an accurate count for lunch.
For additional information, please contact Cory Lytle, Field Sales Representative for Bruker Daltonics: cory.lytle@bruker.com
