{"id":3381,"date":"2026-02-03T16:46:12","date_gmt":"2026-02-03T21:46:12","guid":{"rendered":"https:\/\/www.med.unc.edu\/cryo-em\/?page_id=3381"},"modified":"2026-02-03T17:00:01","modified_gmt":"2026-02-03T22:00:01","slug":"services-2-2-2","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cryo-em\/home-2-2-2\/services-2-2-2\/","title":{"rendered":"Services Provided"},"content":{"rendered":"

Pricing for Our CryoEM Services<\/b><\/h2>\n

We provide transparent pricing for academic and industry partners. All reagents and consumables, and labor are included<\/strong><\/em>. \u00a0A few of the packages we provide for our customers are listed below. \u00a0If you have a challenging sample or difficult cryoEM project we can help design a unique solution that fits your budget and research aims. \u00a0<\/span>\u00a0<\/span><\/p>\n

1. Nanoparticle Characterization. \u00a0<\/span><\/b><\/h4>\n

Cryo-TEM allows for the high-resolution visualization of biological samples in their near-native state. This technique captures the detailed ultra structural of your sample in solution without the structural artifacts caused by heavy metal stains or chemical fixatives. Researchers can accurately characterize the size and internal structure elements of fragile samples. This includes lipid nanoparticles, virus like particle, peptide based nano-particles, extracellular vesicles, or other large macromolecules. \u00a0Ideal for characterizing size, morphology, and the regularity of polymorphic samples approx. 50\u2013300 nm. \u00a0<\/i>\u00a0<\/strong><\/p>\n\n\n\n\n\n
Service<\/b>\u00a0<\/span><\/td>\nInternal<\/b>\u00a0<\/span><\/td>\nExternal<\/b>\u00a0<\/span><\/td>\nIndustry<\/b>\u00a0<\/span><\/td>\n<\/tr>\n
Basic (Lacey Grids)<\/span>\u00a0<\/span><\/td>\n$1,030<\/span>\u00a0<\/span><\/td>\n$1,720<\/span>\u00a0<\/span><\/td>\n$2,010<\/span>\u00a0<\/span><\/td>\n<\/tr>\n
Advanced (Specialized Grids)<\/span>\u00a0<\/span><\/td>\n$1,740<\/span>\u00a0<\/span><\/td>\n$2,830<\/span>\u00a0<\/span><\/td>\n$3,210<\/span>\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Note: Prices above are estimates for 4 samples. Single-sample screening starts at $260 (Internal) \/ $430 (External) \/ $500 (Industry)<\/strong><\/span><\/i><\/p>\n

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2. Cryo-EM Specimen Preparation and Screening (SPA and Cryo-ET). <\/span><\/b><\/h4>\n

<\/b>We provide a comprehensive Sample-to-Structure workflow for both Single-Particle Analysis (SPA) and Cryo-Electron Tomography (cryo-ET).<\/strong> Send us your sample and we will send you the data for your structure. We prepare cryo-grids and perform rigorous screening to optimize freezing conditions specifically for your project. We are highly experienced in working with “difficult” samples that suffer from preferred orientation, low-abundance or dilute samples and complexes that fall-apart at the air-water interface (AWI).<\/p>\n\n\n\n\n\n
Service<\/span><\/b>\u00a0<\/span><\/td>\nInternal<\/span><\/b>\u00a0<\/span><\/td>\nExternal<\/span><\/b>\u00a0<\/span><\/td>\nIndustry<\/span><\/b>\u00a0<\/span><\/td>\n<\/tr>\n
Multiple Sample Session<\/span>\u00a0<\/span><\/td>\n$1,260<\/span>\u00a0<\/span><\/td>\n$2,040<\/span>\u00a0<\/span><\/td>\n$2,440<\/span>\u00a0<\/span><\/td>\n<\/tr>\n
One Sample Rate<\/span>\u00a0<\/span><\/td>\n$630<\/span>\u00a0<\/span><\/td>\n$1,020<\/span>\u00a0<\/span><\/td>\n\n

$1,220<\/span>\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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3. High-Resolution Data Collection<\/span><\/b><\/h4>\n

Why waste more money than you have to?<\/span><\/b>\u00a0We are cryoTEM data collection experts. You might not need 24 hours of beam time to get a structure. Our instruments are set up for rapid data collection to save you time and money. \u00a0<\/span>\u00a0<\/span><\/p>\n\n\n\n\n\n\n
Duration<\/span><\/b>\u00a0<\/span><\/td>\nInternal<\/span><\/b>\u00a0<\/span><\/td>\nExternal<\/span><\/b>\u00a0<\/span><\/td>\nIndustry<\/span><\/b>\u00a0<\/span><\/td>\n<\/tr>\n
Short Session (5 hours)<\/span>\u00a0<\/span><\/td>\n$600<\/span>\u00a0<\/span><\/td>\n$1,100<\/span>\u00a0<\/span><\/td>\n$1,220<\/span>\u00a0<\/span><\/td>\n<\/tr>\n
Overnight Session (16 hours)<\/span>\u00a0<\/span><\/td>\n$1,290<\/span>\u00a0<\/span><\/td>\n$2,240<\/span>\u00a0<\/span><\/td>\n$2,590<\/span>\u00a0<\/span><\/td>\n<\/tr>\n
Full Day Session (24 hours)<\/span>\u00a0<\/span><\/td>\n$1,600<\/span>\u00a0<\/span><\/td>\n$2,640<\/span>\u00a0<\/span><\/td>\n$3,160<\/span>\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What to Expect When You Work with Our Core.<\/span><\/b>\u00a0<\/span><\/h2>\n