{"id":3010,"date":"2023-04-13T17:18:50","date_gmt":"2023-04-13T21:18:50","guid":{"rendered":"https:\/\/www.med.unc.edu\/cryo-em\/?p=3010"},"modified":"2023-04-13T17:24:11","modified_gmt":"2023-04-13T21:24:11","slug":"scientists-take-another-step-toward-creating-better-pain-medications","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/cryo-em\/2023\/04\/scientists-take-another-step-toward-creating-better-pain-medications\/","title":{"rendered":"Scientists Take Another Step Toward Creating Better Pain Medications"},"content":{"rendered":"

CHAPEL HILL, NC \u2013 In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides. Subsequent structure-guided biochemical studies were then performed to better understand the mechanisms of peptide-receptor selectivity and signaling drugs.<\/p>\n

This work,\u00a0published in\u00a0Cell<\/em><\/a>, provides a comprehensive structural framework that should help drug developers rationally design safer drugs to relieve severe pain. Read more<\/a><\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

CHAPEL HILL, NC \u2013 In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides. Subsequent structure-guided biochemical studies were then performed to better understand the mechanisms of peptide-receptor selectivity and … Read more<\/a><\/p>\n","protected":false},"author":93771,"featured_media":3013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[3],"tags":[],"class_list":["post-3010","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nScientists Take Another Step Toward Creating Better Pain Medications - Cryo EM Core<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cryo-em\/2023\/04\/scientists-take-another-step-toward-creating-better-pain-medications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Scientists Take Another Step Toward Creating Better Pain Medications - Cryo EM Core\" \/>\n<meta property=\"og:description\" content=\"CHAPEL HILL, NC \u2013 In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides. 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