{"id":2274,"date":"2014-06-04T19:35:00","date_gmt":"2014-06-04T23:35:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/csb\/mx\/services\/diffraction-services\/"},"modified":"2026-04-14T13:21:10","modified_gmt":"2026-04-14T17:21:10","slug":"diffraction-services","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/csb\/mx\/services\/diffraction-services\/","title":{"rendered":"Diffraction Services"},"content":{"rendered":"<p class=\" \"><span style=\"color: #666666\">For all diffraction services, only crystals are required. The facility provides all the other necessary components and tools to conduct the experiments. For small molecule x-ray diffraction, we route users and crystals to the <a href=\"https:\/\/chem.unc.edu\/critcl-main\/critcl-x-ray\/\" target=\"_blank\" rel=\"noopener noreferrer\">UNC CRITCL (Chemical Research Instrumentation Teaching &amp; Core Labs) X-ray Core Laboratory (XCL)<\/a>. Macromolecular x-ray diffraction experiments are conducted at the same site as the crystallography facility using the following constellation of instrumentation:<\/span><\/p>\n<p><strong>General Crystallography Laboratory Use<\/strong><\/p>\n<ul>\n<li>The Crystallography lab is fully equipped to facilitate all manners of crystal examination, manipulation, cryo-preservation and storage.<\/li>\n<\/ul>\n<p><strong>X-Ray Diffraction<\/strong><\/p>\n<ul>\n<li>A new Bruker Venture D8 with dual sealed sources (moly and copper), Oxford cryosystems cryocooling, and a PHOTON IIIc shutterless pixel array detector.<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-2495 size-medium\" src=\"https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-237x300.jpg\" alt=\"Drs Chen and Nicely stand next to the new Venture D8.\" width=\"237\" height=\"300\" srcset=\"https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-237x300.jpg 237w, https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-809x1024.jpg 809w, https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-768x973.jpg 768w, https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-1213x1536.jpg 1213w, https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-1617x2048.jpg 1617w, https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-600x760.jpg 600w, https:\/\/www.med.unc.edu\/csb\/mx\/wp-content\/uploads\/sites\/907\/2023\/04\/20230425_151728-scaled.jpg 2022w\" sizes=\"auto, (max-width: 237px) 100vw, 237px\" \/><\/p>\n<p>Drs Chen and Nicely next to the new Venture D8.<\/p>\n<p><strong>Computer Resources<\/strong><\/p>\n<ul>\n<li>The core facility has its own computer server that provides users with disk space to analyze their diffraction data. Contact the <a title=\"\" href=\"https:\/\/www.med.unc.edu\/csb\/mx\/contact\/\" target=\"_self\" rel=\"noopener noreferrer\">Director<\/a> about getting an account setup.<\/li>\n<\/ul>\n<p><strong>Synchrotron Access<\/strong><\/p>\n<ul>\n<li>UNC is a founding member of <a href=\"https:\/\/www.ser.aps.anl.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">SER-CAT<\/a> (sector 22 at the Advanced Photon Source) and continues to support two shares thereof. This affords us 288 hours of synchrotron beamtime annually, split evenly over two hutches (22-ID and 22-BM). This facility coordinates usage of this beam time. Contact the <a title=\"\" href=\"https:\/\/www.med.unc.edu\/csb\/mx\/contact\/\" target=\"_self\" rel=\"noopener noreferrer\">Director<\/a> for more information about access to beamtime.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>For all diffraction services, only crystals are required. The facility provides all the other necessary components and tools to conduct the experiments. For small molecule x-ray diffraction, we route users and crystals to the UNC CRITCL (Chemical Research Instrumentation Teaching &amp; Core Labs) X-ray Core Laboratory (XCL). Macromolecular x-ray diffraction experiments are conducted at the &hellip; <a href=\"https:\/\/www.med.unc.edu\/csb\/mx\/services\/diffraction-services\/\" aria-label=\"Read more about Diffraction Services\">Read more<\/a><\/p>\n","protected":false},"author":22429,"featured_media":0,"parent":2259,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2274","page","type-page","status-publish","hentry","odd"],"acf":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/pages\/2274","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/users\/22429"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/comments?post=2274"}],"version-history":[{"count":1,"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/pages\/2274\/revisions"}],"predecessor-version":[{"id":2536,"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/pages\/2274\/revisions\/2536"}],"up":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/pages\/2259"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/csb\/mx\/wp-json\/wp\/v2\/media?parent=2274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}