{"id":2239,"date":"2019-08-14T13:55:35","date_gmt":"2019-08-14T17:55:35","guid":{"rendered":"https:\/\/www.med.unc.edu\/cvi\/?page_id=2239"},"modified":"2021-09-29T09:53:48","modified_gmt":"2021-09-29T13:53:48","slug":"home","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/cvi\/","title":{"rendered":"Home"},"content":{"rendered":"

Welcome!<\/span><\/h2>\n

The UNC Chlamydia Vaccine Initiative STI Cooperative Research Center is a partnership of academic institutions and industry to explore systems-level host\/pathogen molecular interactions during infection of the female genital tract by Chlamydia trachomatis <\/em>(CT).<\/p>\n

<\/div>\n
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Fallopian tube epithelium cells infected with Chlamydia trachomatis<\/em>. Red: C. trachomatis<\/em>, Green: cilia, White: actin, Blue: nuclei.<\/figcaption><\/figure>\n

C. trachomatis <\/em>is a sexually-transmitted bacterium that infects over 100 million people worldwide. In the United States, more than 1 million women are infected annually. When left untreated, CT infection can lead to Pelvic Inflammatory Disease (PID), chronic pelvic pain, ectopic pregnancy and infertility.<\/p>\n

Our goal is to accelerate development of a novel vaccine that prevents CT ascension in the female genital tract, eliminating CT-associated PID and infertility. We aim to go further and develop a vaccine regimen that fully prevents CT infection.<\/p>\n

Our objectives are to identify vaccine candidates that are protective in animal models, suitable vehicles to deliver them, and biomarkers to evaluate their efficacy clinically.<\/p>\n

The UNC Chlamydia Vaccine Initiative is funded by the National Institute of Allergy and Infectious Diseases (Project ID: 1 U19 AI144181-01).<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

The UNC Chlamydia Vaccine Initiative STI Cooperative Research Center is a partnership of academic institutions and industry to explore systems-level host\/pathogen molecular interactions during infection of the female genital tract by Chlamydia trachomatis (CT). C. trachomatis is a sexually-transmitted bacterium that infects over 100 million people worldwide. In the United States, more than 1 million … Read more<\/a><\/p>\n","protected":false},"author":81071,"featured_media":2265,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2239","page","type-page","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nHome - UNC Chlamydia Vaccine Initiative<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/cvi\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Home - UNC Chlamydia Vaccine Initiative\" \/>\n<meta property=\"og:description\" content=\"The UNC Chlamydia Vaccine Initiative STI Cooperative Research Center is a partnership of academic institutions and industry to explore systems-level host\/pathogen molecular interactions during infection of the female genital tract by Chlamydia trachomatis (CT). 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