The following individuals are currently serving as Principal Investigators on projects administered by the Center for Women’s Health Research. Links to detailed information about each study are available on the Current Research page.

Victoria Bae-Jump, MD, PhD

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Inter-relationship between microbiota diversity, obesity and race in endometrial cancer
  • Metabolic and Molecular Biomarkers of Metformin Response in Obesity-driven Endometrial Cancer
Research Profile:

Dr. Bae-Jump focuses on understanding the interactions between cell signaling pathways implicated in endometrial cancer pathogenesis as a means to target therapy for this disease. She is also interested in the impact that obesity has on endometrial cancer development and progression which may invariably dictate different treatment options for this particularly high-risk patient population.

Margaret (Peggy) Bentley - Department of Nutrition, Gillings School of Global Public Health

Margaret (Peggy) Bentley, MA, PhD

Department of Nutrition, Gillings School of Global Public Health
Profile

Current CWHR Administered Studies:
  • Mothers and Others: Family-based Obesity Prevention for Infants and Toddlers
Research Profile:

Dr. Bentley’s research focuses on nutrition for women and infants, infant and young child feeding, and community-based interventions for nutrition and health, with a focus on India, Africa, and the U.S. Shehasexpertiseinboth qualitative and quantitative research methods and the application of these techniques for program development and evaluation. She also conducts behavioral research on sexually transmitted diseases, HIV, and community-based interventions for nutrition and health.

Kim Boggess, MD - Division of Maternal Fetal Medicine

Kim Boggess, MD

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Antihypertensive Therapy for Mild Chronic Hypertension during Pregnancy (CHAP Project)
  • Building Interdisciplinary Research Careers in Women’s Health (BIRCWH)
  • Medical optimization & management of pregnancies with overt type 2 diabetes (MOMPOD)
  • Non-Destructive Isolation of Trophoblast Subtypes
  • Phase II Study of Nicotinamide (Vitamin B3-Amide) in Early-Onset Preeclampsia
Research Profile:

Dr. Boggess has a special interest in inflammation on pregnancy outcomes and was the first investigator to report an association between maternal periodontal infection and preeclampsia. She has expertise in preeclampsia, inflammation, immune responses, sFlt-1 and utilizing laboratory animals (mice) in research.

Geller

Elizabeth Geller, MD

Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Permanent Versus Absorbable Colpopexy Trial (PACT)
  • Prospective, Multi-Center, Randomized, Double-Blinded, Partial Crossover Trial of Percutaneous Tibial Nerve Stimulation with the Bioness Stimrouter Neuromodulation System Versus Sham in the Treatment of Overactive Bladder (OAB)
Research Profile:

Dr. Gellerhasexpertiseinthe areas of pelvic floor support, pelvic floor function, and both conservative and surgical correction of pelvic floor dysfunction including bladder, bowel and sexual function.

Hendree Jones, PhD

Director, UNC Horizons

Director of the CWHR Substance Abuse Core
Profile

Current CWHR Administered Studies:
  • Development and Training of Four Advanced Courses Comprising the Universal Treatment Curriculum
Research Profile:

Dr. Jones focuses on developing and testing behavioral and/or pharmacological treatments to treat women (especially pregnant women) for substance use disorders. Her work includes adapting and testing behavioral treatments combined with HIV prevention to reduce substance use and HIV risk behaviors in women in international settings.

Michele Jonsson-Funk

Michele Jonsson-Funk, PhD

Department of Epidemiology, Gillings School of Global Public Health
Profile

Current CWHR Administered Studies:
  • Methods for Estimating Sex Differences in Safety and Effectiveness of Drugs
Research Profile:

Dr. Jonsson-Funk is a pharmacoepidemiologist with a particular interest in epidemiology methods. Currently, she focuses on evaluating the application of doubly robust estimators to comparative effectiveness research in observational data and developing methods to estimate sex differences in the safety and effectiveness of cardiovascular drugs. She has experience working in a range of substantive areas including antiretroviral treatment for HIV and the effect of OTC analgesics on pregnancy outcomes.

Tracy Manuck, MD, MS

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Pharmacogenomics of Preterm Birth Prevention and Treatment
Research Profile:

Dr. Nicholson’s research focuses on the epidemiology of chronic conditions in women, including gestational diabetes, type 2 diabetes, obesity and the effect of depressive symptoms on health-related quality of life. She is currently the Director of CWHR’s Obesity and Diabetes Core.

Hazel Nichols, PhD

Department of Epidemiology, Gillings School of Global Public Health
Profile

Current CWHR Administered Studies:
  • Clinical Pregnancy Outcomes in Adolescent and Young Adult Female Cancer Survivors
Research Profile:

Dr. Nichols’ research addresses hormonally-related factors that are considered during health care delivery (e.g. contraception, breastfeeding, gynecologic surgery, postmenopausal obesity, hormone therapy) and may be targeted by interventions to prevent breast cancer or improve post-diagnosis outcomes.

Lisa Rahangdale, MD, MPH

Division of General Obstetrics & Gynecology, Department of Obstetrics and Gynecology, School of Medicine &  Senior Medical Director for OB-GYN Ambulatory 
Profile

Current CWHR Administered Studies:
  • Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSIL
Research Profile:

Dr. Anna Maria Siega-Riz, Ph.D., Department of Epidemiology & Nutrition, and Associate Dean of Academic Affairs, School of Public Health

Anna Maria Siega-Riz, PhD

Departments of Epidemiology & Nutrition, Gillings School of Global Public Health

Current CWHR Administered Studies:
  • Diet, Obesity and Weight Change in Pregnancy
Research Profile:

Dr. Siega-Riz, a nutritional epidemiologist, uses a multidisciplinary team perspective as a way to address complex problems such as prematurity, fetal programming, racial disparities, and obesity. She has been involved in several large cohort studies involving pregnant women, children, and Hispanics as well as one multi-centered intervention study for preventing type 2 diabetes in middle school children. She is interestedinusingcutting-edgemethodologytoassess dietary intake for the purpose of examining the relationship between maternal diet and birth outcomes as well as prenatal determinants of childhood obesity. Her work also involves the determinants and consequences of gestational weight gain as well as the influence of maternal obesity on short-and long-term maternal and child health outcomes.

Anne Steiner, MD, MPH - Division of Reproductive Endocrinology and Infertility

Anne Steiner, MD, MPH

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Cooperative Multicenter Reproductive Medicine Network
Research Profile:

Dr. Steiner has an interestandexpertiseininfertility, in vitro fertilization (IVF), reproductive aging, hysteroscopy, and amenorrhea (absent menses). She is nationally known for her research on biomarkers of ovarian aging as predictors of reproductive potential and has secured funding for her research from the National Institutes of Health (NIH) since 2006.

Gretchen Stuart, MD, MPH - Division of Women's Primary Healthcare

Gretchen Stuart, MD, MPH

Division of Women’s Primary Healthcare, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • A Phase 3, Randomized, Multi-Center, Open-Label Study of a Levonorgestrel-Releasing Intrauterine System (20 mcg/day) and Mirena® for Long-Term, Reversible Contraception up to Five Years
  • Pilot Bi-Lateral Tubal Occlusion Trial for Female Permanent Contraception
Research Profile:

Dr. Stuart’s clinical and research work includesoutpatientgynecology, genital tract infections, sexually transmitted infection, HIV/AIDS, and contraception.

Alison Stuebe

Alison Stuebe, MD

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Mood, mother, and infant: The psychobiology of impaired dyadic development
Research Profile:

Dr. Stuebe’s research focuses on modifiable risk factors for metabolic disease in the perinatal period, and she has authored more than 20 peer-reviewed publications on gestational diabetes, pregnancy-associated weight gain, and the maternal health effects of lactation. Current research projects include the effects of postpartum depression on breastfeeding physiology, the role of subclinical infection in breast pain, and the etiology of racial and ethnic disparities in breastfeeding. In the clinical arena, she leads an interdisciplinary team of UNC clinicians that is developing new approaches to management of breastfeeding difficulties. Her areas of interest include Breastfeeding and Lactation Consultation; Gestational Diabetes; and Postpartum Depression.

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John Thorp, Jr., MD

Division of Women’s Primary Healthcare, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • Cooperative Multicenter Maternal Fetal Medicine Units Network
  • Pulmonary Complications in a Birth Cohort after a Randomized Trial of Exposure to Antenatal Corticosteroids: the ALPS Follow-Up Study
Research Profile:

Dr. Thorp’s research interests include preterm birth, cervical insufficiency, clinical trials, nutrition in pregnancy, health disparities, alcohol, and drug abuse research, and outreach education. Dr. Thorp has led the UNC Maternal FetalMedicine Unit Network site since 2000.

Neeta Vora

Neeta Vora, MD

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine
Profile

Current CWHR Administered Studies:
  • A New Era of Genomics for Fetal Diagnosis
Research Profile:

Dr. Vora’s research explores reproductive genetics and prenatal diagnosis as they pertain to maternal obesity, fetal neurodevelopment, preterm labor, and growth parameters.

Jennifer Wu

Jennifer Wu, MD, MPH

Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, School of Medicine

Director of the CWHR Pelvic Floor Disorders Core
Profile

Current CWHR Administered Studies:
  • LIBERATE: A Clinical Evaluation of the…
  • Pelvic Floor Disorders Network Data Coordinating Center
  • Xenform Postmarket Surveillance Study
Research Profile:

Dr. Wu pursues clinical and translational research in epidemiology, genetic epidemiology, and pharmacogenomics. Her long-term career goal is to substantially improve women’s health as a well-trained, independent clinician-scientist who can use innovative tools to identify the root causes of pelvic floor disorders and to translate these findings into improved clinical practice. She is also the CWHR Director of the Pelvic Health Core.