Current Research

The Center for Women’s Health Research provides support for Clinical Trials and Research Grants. The following studies are currently underway:

Clinical Trials

LIFE: LivSure for Fecal Incontinence. A clinical evaluation of LivSure vaginal bowel control (VBC) device for the treatment of fecal incontinence in women.

  • Pelvalon, Inc
  • Dr. Catherine Matthews, Obstetrics and Gynecology
  • 3/7/2013 to 3/6/2015
  • $83,916.59

Manual liquid based cytology

  • chemQ Bioscience
  • Dr. Lisa Rahangdale, Obstetrics and Gynecology
  • 4/1/2013 to 3/31/2015
  • $15,728.12

Pelvic Floor Disorders Network Data Coordinating Center

  • Research Triangle Institute
  • Dr. AnnaMarie Connolly, Obstetrics and Gynecology
  • 8/1/2011 to 6/30/2014
  • $203,951.00

A Phase 3, Randomized, Multi-Center, Open-Label Study of a Levonorgestrel-Releasing Intrauterine System (20 mcg/day) and Mirena® for Long-Term, Reversible Contraception up to Five Years

  • Medicines360
  • Dr. Gretchen Stuart, Obstetrics and Gynecology
  • 4/17/2012 to 4/16/2018
  • $92,279.30

Pharmacokinetics, pharmacodynamics, and genital tract viral shedding in HIV+ women using combined oral contraceptives and raltegravir

  • Merck Sharp and Dohme
  • Dr. Gretchen Stuart, Obstetrics and Gynecology
  • 5/30/2012 to 5/29/2015
  • $97,165.13

Research Grants

Cooperative Multicenter Maternal Fetal Medicine Units Network

  • National Institute of Child Health and Human Development
  • Dr. John Thorp, Obstetrics and Gynecology
  • 4/18/2001 to 3/31/2016 (still open)
  • $9,385,972

Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) Study

  • University of Alabama at Birmingham
  • Dr. Kim Boggess, Obstetrics and Gynecology
  • 9/20/2010 to 7/31/2014
  • $557,902.00

HIV and Drug Use in Georgian Women

  • NIH National Institute on Drug Abuse (NIDA)
  • Dr. Hendree Jones, Obstetrics and Gynecology, UNC Horizons
  • 9/30/2010 to 6/30/2015
  • $523,029.00

Biomarkers of Infertility (Time to Conceive extension)

  • National Institute of Child Health and Human Development (NICHD)
  • Dr. Anne Steiner, Obstetrics and Gynecology
  • 4/15/2011 to 3/31/2016
  • $1,703,233.00

Transitional Research in Pelvic Floor Disorders

  • National Institute of Child Health and Human Development (NICHD)
  • Dr. Jennifer Wu, Obstetrics and Gynecology
  • 5/15/2011 to 4/30/2015
  • $127,197.00

FMR1 CGG Repeats In Primary Ovarian Insufficiency Women vs. 2 Comparison Groups

  • University of Virginia
  • Dr. Steven Young, Obstetrics and Gynecology
  • 9/15/2011 to 6/30/2014
  • $56,134.00

Progesterone Action in the Endometrium of Women with Endometriosis

  • National Institute of Child Health and Human Development (NICHD)
  • Dr. Steven Young, Obstetrics and Gynecology
  • 9/15/2011 to 6/30/2016
  • $1,929,568.00

Understanding the Response to Fesoterodine through Genetic Evaluation in the Elderly (URGE)

  • NIH National Institute on Aging (NIA)
  • Dr. Jennifer Wu, Obstetrics and Gynecology
  • 8/1/2012 to 7/31/2014
  • $123,443.00

Mothers and Others: Family-based Obesity Prevention for Infants and Toddlers

  • National Institute of Child Health and Human Development (NICHD)
  • Dr. Margaret (Peggy) Bentley, Nutrition
  • 9/1/2012 to 6/30/2017
  • $1,188,907.00

A Transgenerational e-Intervention for Gestational Diabetics and their Offspring

  • NIH National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDKD)
  • Dr. Wanda Nicholson, Obstetrics and Gynecology
  • 4/1/2013 to 3/31/2015
  • $228,000.00

Mood, mother and infant: The psychobiology of impaired dyadic development

  • NIH National Institute of Child Health and Human Development (NICHD)
  • Dr. Alison Stuebe, Obstetrics and Gynecology
  • 4/1/2013 to 3/31/2018
  • $513,109.00

Gestational Length and Fetal Growth in the Time to Conceive Sub-study

  • Social and Scientific Systems (S3), Inc.
  • Dr. Anne Steiner, Obstetrics and Gynecology
  • 6/1/2013 to 5/31/2015
  • $31,188.00

Reinforced Treatment for Pregnant Drug Abusers (Home II)

  • Johns Hopkins University
  • Dr. Hendree Jones, UNC Horizons, Obstetrics and Gynecology
  • 6/1/2013 to 5/31/2014
  • $34,124.00

Cooperative Multicenter Reproductive Medicine Network UNC Clinical Site

  • NIH National Institute of Child Health and Human Development (NICHD)
  • Dr. Anne Steiner, Obstetrics and Gynecology
  • 9/24/2013 to 6/30/2018
  • $315,608.00

Diet, Obesity, and Weight Change in Pregnancy

  • NIH National Institute of Child Health and Human Development (NICHD)
  • Dr. Myles Faith, Nutrition
  • 9/27/2013 to 3/26/2015
  • $672,141.00

Improving Women's Sexual Health While in Drug Addiction Treatment

  • NIH National Institute on Drug Abuse (NIDA)
  • Dr. Hendree Jones, UNC Horizons, Obstetrics and Gynecology
  • 9/30/2013 to 8/31/2016
  • $210,159.00

Methods for estimating sex differences in safety and effectiveness of drugs

  • NIH National Heart, Lung, and Blood Institute (NHLBI)
  • Dr. Michele Jonsson-Funk, Epidemiology
  • 5/1/2014 to 4/30/2018
  • $512,523.00