Charles S. Ebert, Jr., MD, MPH

Charles Ebert

Associate Professor
Associate Director, Residency Program
Co-Director, Rhinology & Skull Base Surgery Fellowship


  • Endoscopic Skull Base Tumor Surgery
  • Encephalocele Repair and Management of CSF Rhinorrhea
  • Primary and Revision Endoscopic Sinus Surgery
  • Nasal Airway Surgery
  • Chronic Sinus Disease
  • Allergic Fungal Rhinosinusitis
  • Sino-Nasal Tumors
  • Allergic Disease


  • MD: University of North Carolina School of Medicine, 2002
  • MPH (Epidemiology): University of North Carolina School of Public Health, 2002
  • Residency: Otolaryngology/Head and Neck Surgery, UNC, 2002-2009
  • Residency: National Institutes of Health National Research Service Award Fellowship, 2003-2005
  • Fellowship: Georgia Nasal and Sinus Institute, 2009

Professional Experience

  • Assistant Professor, Dept. of Otolaryngology/Head and Neck Surgery, University of North Carolina School of Medicine, 2009-present

Recent Publications

  • Taylor RJ, Miller JD, Rose AS, Drake AF, Zdanski CJ, Senior BA, Ebert CS Jr, Zanation AM. “Comprehensive quality of life outcomes for pediatric patients undergoing endoscopic sinus surgery.” Rhinology. 2014 Dec;52(4):327-333. PMID: 25479210
  • Thorp BD, Sreenath SB, Ebert CS Jr, Zanation AM. "Endoscopic Skull Base Reconstruction: A Review and Clinical Case Series of 152 Vascularized Flaps Utilized for Surgical Skull Base Defects in the Setting of Intraoperative Cerebrospinal Fluid Leak" Neurosurg Focus. 2014 Oct:37(4):E4. PMID: 25270144
  • Austin GK, McKinney KA, Ebert CS Jr, Zanation AM. “Imaged-guided robotic skull base surgery.” J Neurol Surg B Skull Base. 2014 Aug;75(4):231-235. PMID: 25093145
  • Ebert CS Jr, McKinney KA, Urrutia G, Wu M, Rose AS, Fleischman GM, Thorp BD, Senior BA, Zanation AM. “Expression of protease-activated recetpors in allergic fungal rhinosinusitis”. Int Forum Allergy Rhinol. 2014 Apr;4(4):266-71. PMID: 24500840
  •  Miller JD, Deal AM, McKinney KA, McClurg SW, Rodriguez KD, Thorp BD, Senior BA, Zanation AM, Ebert CS Jr. “Markers of disease severity and socioeconomic factors in allergic fungal rhinosinusitis”. Int Forum Allergy Rhinol. 2014 Apr;4(4):272-9. PMID: 24449482
  • Fleischman GM, Ambrose EC, Rawal RR, Huang BY, Ebert CS Jr,, Rodriguez KD, Zanation AM, Senior BA. “Obstructive Sleep Apnea in Patients Undergoing Endoscopic Surgical Repair of Cerebrospinal Fluid Rhinorrhea”. Laryngoscope.  2014 Mar 3. doi: 10.1002/lary.24661. PMID: 24591190
  • Fleischman GM, Miller JD, Kim GG, Zanation AM, Ebert CS Jr. “Treatment of chronic frontal sinusitis with difficult anatomy: A hybrid balloon technique in four cases”. Allergy Rhinol (Providence). 2014 Jan;5(3)120-124. PMID: 25565046
  • Frank DO, Zanation Am, Dhanda VH, McKinney KA, Fleischman GM, Ebert CS Jr, Senior BA, Kimbell JS. "Qualification of airflow into the maxillary sinus before and after functional endoscopic sinus surgery". Int Forum Allergy Rhinol. 2013. Oct; 3(10): 834-40
  • Rose AS, Thorp BD, Zanation AM, Ebert CS Jr. "Chronic rhinosinusitis in children." Pediatr Clin North Am 2013. Aug; 60(4):979-991
  • Farag AA, Deal AM, McKinney KA, Thorp BD, Senior BA, Ebert CS Jr, Zanation AM. “Single-blind randomized controlled trial of surfactant versus hypertonic saline irrigation following endoscopic endonasal surgery in the early post-operative period”. Accepted, Int Forum Allergy Rhinol, 2013.
  • Gore MR, Ebert CS Jr, Zanation AM, Senior BA. "beyond the "central sinus": radiographic findings in patients undergoing revision functional endoscopic sinus surgery". Int Forum Allergy Rhinol. 2013. Feb; 3(2): 139-146
  • Thorp BD, McKinney KA, Mitchell CA, Rose AS, Zanation AM, Ebert CS Jr. “Allergic Fungal Sinusitis in Children”. Accepted Otolaryngol Clin N Am, 2012 Jun; 45(3):632-642. PMID: 22588040.
  • Mitchell CA, Ebert CS Jr, Buchman CA, Zanation AM. "Combined transnasal/transtemporal managemnt of the Eustachian tube for middle ear inverted papilloma". Laryngoscope 2012; 122(8): 276-280.
  • Little RM, Deal AM, Zanation AM, McKinney KA, Senior, BA, Ebert CS Jr. "Occupational Hazards of Endoscopic Endonasal Surgery". Int Forum Allergy Rhinol. 2012 May-June; 2(3): 212-6
  • Gore MR, Zanation AM, Ebert CS Jr, Senior BA. Cholesterol Granuloma of the Petrous Apex. Otolaryngol Clin North Am 2011 Oct; 44(5): 1043-58
  • Turley R, Cohen SM, Becker A, Ebert CS Jr. “Role of Rhintis in Laryngitis: Another Dimension of the Unified Airway”. Accepted Annals Oto Laryngol Rhinol, 2011.
  • Ebert CS Jr and Pillsbury HC. “The Epidemiology of Allergy”. Otolaryngol Clin N Am. 44:537–548, 2011.
  • Oosmanally N, Paul JE, Zanation AM, Ewend MG, Senior BA, Ebert CS Jr. “Comparative Analysis of Cost of Endoscopic Endonasal Minimally Invasive and Sublabial-transseptal Approaches to the Pituitary”. Int Forum Allergy Rhinol. 2011;1:242-249.
  • Suberman TA, Zanation AM, Ewend MG, Senior BA, Ebert CS Jr. “Sinonasal Quality-of-life before and after Minimally Invasive Pituitary Surgery.” Accepted Int Forum Allergy Rhinol. 2011;1:161-166.
  • Tatreau JR, Patel MR, Shah RN, McKinney KA, Wheless SA, Senior BA, Ewend MG, Germanwala AV, Ebert CS Jr, Zanation AM. “Anatomical considerations for endoscopic endonasal skull base surgery in pediatric patients.” Laryngoscope. 2010 Sep;120(9):1730-1737.
  • McKinney KA, Stadler ME, Ebert CS, Wong YT, Shah RN, Rose AS, Zdanski CJ, Drake AF, Wheless SA, Zanation AM. “Trans-palatal Greater Palatine Canal Injection: Radioanatomic analysis of where to bend the needle for pediatric sinus surgery.” Am J Rhinol Allergy. 24:385–388, 2010.
  • Ebert CS and Senior BA. “A review of minimally invasive pituitary surgery: the evolution from maximally to minimally invasive surgery”. Otorinolaringol 2009:59:97-105.
  • Ebert CS, Zdanski CJ, Ardeshirpour F, Patel MR, Hart CF, Drake AF. “Recurrent Infantile Myofibromatosis: A report of conservative management and discussion of treatment strategies.” Ear Nose Throat J. 2008 Dec;(12):E4.
  • Rose AS, Ebert CS, Prazma J, Pillsbury HC 3rd. “Noise exposure levels in stock car auto racing”. Ear Nose Throat J. 2008 Dec;87(12):689-92.
  • Ebert CS, Zanation AM, Buchman CA. “Another Cause for Conductive Hearing Loss with Present Acoustic Reflexes”. Laryngoscope. 2008 Nov;118(11):2059-61.
  • Blanks DA, Ebert CS. “Immune modulatory oligonucleotides in the prevention and treatment of allergen-induced Eustachian tube dysfunction in the animal model”. Curr Allergy Asthma Rep. 2008 Nov;8(6):508-12.
  • Senior BA, Ebert CS, Kolln K, Bassim MK, Younes M, Sigounas D, Ewend MG. “Triologic Society’s Candidate’s Thesis: Minimally Invasive Pituitary Surgery”. Laryngoscope . 2008 Oct;118(10):1842-55.
  • Lee SC, Ebert CS, Fordham L, Rose AS. “Plain films in the evaluation of batteries as esophageal foreign bodies”. Int J Pediatr Otorhinolaryngol. 2008 Oct;72(10):1487-91.
  • Patel MR, Stamat JC, Zdanski CJ, Ebert CS, Prazma J. “Nitric oxide in glutamate-induced compound action potential threshold shifts”. Hear Res. May;239(1-2):54-9, 2008.
  • Eapen RJ, Ebert CS, Pillsbury HC 3rd. “Allergic rhinitis--history and presentation”. Otolaryngol Clin North Am. Apr;41(2):325-30, vi-vii. Review, 2008.
  • Ebert CS, Blanks DA, Patel MR, Coffey CS, Marshall AF, Fitzpatrick DC. “Behavioral sensitivity to interaural time differences in the rabbit”. Hear Res. 2008 Jan;235(1-2):134-42.
  • Ebert CS, Rose AS, Blanks DA, Eapen RP, Kandimalla ER, Agrawal S, Prazma J, Pillsbury HC, III. “Immune modulatory oligonucleotides in prevention of nasal allergen–induced Eustachian tube dysfunction in rats”. Otolaryngol Head Neck Surg. 2007 Aug;137(2):250-5.
  • Blanks DA, Ebert CS, Eapen RP, Zdanski C, Agrawal S, Prazma J. “Immune modulatory Oligonucleotides in the Prevention and Treatment of OVA-induced Eustachian Tube Dysfunction in Rats”. Otolaryngol Head Neck Surg. Aug;137(2):321-6, 2007.
  • Das S, Kim D, Cannon TY, Ebert CS, Senior BA. High-resolution computed tomography analysis of the greater palatine canal. Am J Rhinol. 2006 Nov-Dec;20(6):603-608.
  • Ebert CS, Rose AS, Patel MR, Hardy SM, Kandimalla ER, Agrawal S, Prazma J, Pillsbury HC. “The role of immunomodulatory oligonucleotides in prevention of OVA-induced Eustachian tube dysfunction.” Int J Pediatr Otorhinolaryngol 70(12):2019-26, 2006.
  • Ardeshirpour F, Ebert CS, Dubin MG, Weissler MC. Radiology quiz case 2. Maxillary osteomyelitis. Arch Otolaryngol Head Neck Surg. Jun;132(6):691-693, 2006.
  • Coffey CS, Ebert CS, Marshall AM, Skaggs JD, Crocker WD, Pearson JM, Fitzpatrick DC. “Detection of Interaural Correlation by Neurons in the Superior Olivary Complex, Inferior Colliculus and Auditory Cortex of the Unanesthetized Rabbit” Hear Res. 221(1-2):1-16, 2006.
  • Bassim MK, Ebert CS, Sit R, Senior BA. “Radiation Dose to the Eyes and Parotids during CT of the Sinuses”. Otolaryngol Head Neck Surg. Oct;133(4):531-3, 2005.
  • Dubin MG, Ebert CS, Coffey CS, Melroy CT, Sonnenburg RE, Senior BA. “Concordance of middle meatal swab and maxillary sinus aspirate in acute and chronic sinusitis: a meta-analysis.” Am J Rhinol. Sep-Oct;19(5):462-70, 2005.
  • Dubin MG, Sonnenburg RE, Melroy CT, Ebert CS, Coffey CS, Senior BA. “Staged endoscopic and combined open/endoscopic approach in the management of inverted papilloma of the frontal sinus” Am J Rhinol. Sep-Oct;19(5):442-5, 2005.
  • Zanation AM, Ebert CS, Coffey CS, Dubin MG, Rose AS. “Precursor B-Cell Lymphoblastic Lymphoma Presenting as Isolated External Ear Swelling in a Two-Year-Old Child”. International J of Pediatr Otorrhinolaryngol- 69(5): 695-699, 2005.
  • Ebert CS Jr, Dublin MG, Chalian AA, Shockley WS. "Clear Cell Odontogenic Carcinoma: A Comprehensive Analysis of Treatment Strategies" Head Neck 27(6):536-42, 2005. PMID: 15772956
  • Ebert CS, Drake AF. “The Impact of Sleep-disordered Breathing on Cognition and Behavior in Children: A Review and Meta-synthesis of the Literature”. Otolaryngol- Head Neck Surg 131(6): 814-826, 2004.