{"id":2213,"date":"2014-10-17T19:10:00","date_gmt":"2014-10-17T23:10:00","guid":{"rendered":"https:\/\/med.sites.unc.edu\/epigenetics\/epigenetics\/people\/"},"modified":"2023-06-12T10:17:56","modified_gmt":"2023-06-12T14:17:56","slug":"people","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/epigenetics\/people\/","title":{"rendered":"Faculty"},"content":{"rendered":"<p class=\"lead\">Meet the investigators involved with epigenetics research:<\/p>\n<h2>Leadership<\/h2>\n<div class=\"container-fluid divisions-container multi-column\">\n    \n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/jdowen-image.jpg\" alt=\"Jill Dowen, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/jdowen-image.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jill-dowen-phd\/\" rel=\"bookmark\">\n                            Jill Dowen, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Chromatin and Epigenetics Leadership Committee<\/p>\n<p><span style=\"color: #000000\">Three-dimensional genome architecture and gene regulation<\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Magnuson2.jpeg\" alt=\"Terry Magnuson, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Magnuson2.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/terry-magnuson\/\" rel=\"bookmark\">\n                            Terry Magnuson, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Chromatin and Epigenetics Leadership Committee<\/p>\n<p>The work in the Magnuson lab focuses on the role of mammalian genes in unique epigenetic phenomena such as genomic imprinting, X-chromosome inactivation, stem cell pluripotency and the tumor suppressor role of chromatin remodeling complexes.<\/p>\n<p><span style=\"color: #000000\">\u00a0<\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/McGinty-image.jpg\" alt=\"Robert McGinty, MD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/McGinty-image.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/robert-mcginty-md-phd\/\" rel=\"bookmark\">\n                            Robert McGinty, MD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Chromatin and Epigenetics Leadership Committee<\/p>\n<p>The McGinty lab uses protein chemistry and structural biology to understand mechanisms underlying signaling through chromatin in health and disease.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/08\/Samantha-Pattenden400x400.jpg\" alt=\"Samantha Pattenden, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/08\/Samantha-Pattenden400x400.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/samantha-pattenden-phd\/\" rel=\"bookmark\">\n                            Samantha Pattenden, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Chromatin and Epigenetics Leadership Committee<\/p>\n<p>Techniques in chromatin-based therapeutic discovery and cancer diagnostics.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Brian_D_Strahl-copy.jpg\" alt=\"Brian Strahl, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Brian_D_Strahl-copy.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/brian-strahl-phd\/\" rel=\"bookmark\">\n                            Brian Strahl, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Chromatin and Epigenetics Leadership Committee<\/p>\n<p>Our lab is addressing how histone post-translational modifications, and the combinatorial codes they create, contribute to the structure and function of chromatin.<\/p>\n<p>&nbsp;<\/p>\n                            <\/div>\n        <\/article>\n\n    \n    <script type=\"text\/javascript\">\n        (function($){\n            var entries = $('.entry-content');\n                entries.each(function(index, entry ){\n                    if( $(entry).find('.post-author').length === 0 ) {\n                        $(entry).parents('article.post.entry').css('min-height', '110px');\n                    }\n                });\n        })(jQuery);\n    <\/script>\n\n<\/div>\n\n\n<h2>Members<\/h2>\n<div class=\"container-fluid divisions-container multi-column\">\n    \n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2014\/10\/TrevorArcherProfile-NIEHS.jpg\" alt=\"Trevor Archer, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2014\/10\/TrevorArcherProfile-NIEHS.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/trevor-archer-phd\/\" rel=\"bookmark\">\n                            Trevor Archer, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our research group studies the interplay of chromatin and epigenetics in stem cell and cancer biology with a focus on epigenetic responses to physiological and environmental exposures.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/03\/Bloom-cropped.jpg\" alt=\"Kerry Bloom, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/03\/Bloom-cropped.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/kerry-bloom-phd\/\" rel=\"bookmark\">\n                            Kerry Bloom, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our laboratory studies how epigenetic marks influence chromosome territories and dynamics.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Calabrese.jpeg\" alt=\"J. Mauro Calabrese, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Calabrese.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/j-mauro-calabrese-phd\/\" rel=\"bookmark\">\n                            J. Mauro Calabrese, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Calabrese lab studies the mechanisms through which long noncoding RNAs regulate epigenetic states in normal and cancerous genomes.<\/p>\n<p>&#160;<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/chen.jpg\" alt=\"Xian Chen, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/chen.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/xian-chen-phd\/\" rel=\"bookmark\">\n                            Xian Chen, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Development and application of novel systems biology (functional proteomics) approaches to characterize phenotypic epigenetic protein machinery that impact gene regulation.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Conlon.jpeg\" alt=\"Frank L. Conlon, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Conlon.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/frank-l-conlon-phd\/\" rel=\"bookmark\">\n                            Frank L. Conlon, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our lab is studying the protein complexes involved in gene regulation in vertebrate heart development and human congenital heart disease.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Cook-image.jpeg\" alt=\"Jean Cook, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Cook-image.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jean-cook-phd\/\" rel=\"bookmark\">\n                            Jean Cook, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>DNA replication origin licensing and chromatin in metazoans<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/CronaDan.jpg\" alt=\"Daniel Crona, PharmD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/CronaDan.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/daniel-crona\/\" rel=\"bookmark\">\n                            Daniel Crona, PharmD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p><span style=\"color: rgb(51, 51, 51); \">The Crona lab is interested in characterizing the clinical pharmacology (pharmacokinetics, pharmacodynamics, germline pharmacogenetics) of epigenetic pharmacotherapeutics used in the treatment of cancer.<\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/IDavis_crop.jpeg\" alt=\"Ian J. Davis, MD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/IDavis_crop.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/ian-davis-phd\/\" rel=\"bookmark\">\n                            Ian J. Davis, MD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Through the use of genome-wide approaches, the Davis lab is interested in basic and translational aspects of chromatin biology in cancer and development.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/duronio-robert-200X250.jpg\" alt=\"Bob Duronio, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/duronio-robert-200X250.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/robert-duronio-phd\/\" rel=\"bookmark\">\n                            Bob Duronio, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Epigenetic control of DNA replication and cell proliferation during animal development<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Fry_2024-1024x980.jpeg\" alt=\"Rebecca Fry, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Fry_2024-1024x980.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/rebecca-fry-phd\/\" rel=\"bookmark\">\n                            Rebecca Fry, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Fry Lab is interested in understanding how life course exposure to environmental chemicals (including arsenic, cadmium, lead, and PFAS) reshapes epigenetic regulation and molecular pathways to drive adverse health outcomes, including cancer, using integrated mechanistic studies, experimental models, and human population cohorts.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/07\/Jime-pic-1-002.jpg\" alt=\"Jimena Giudice, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/07\/Jime-pic-1-002.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jimena-giudice-phd\/\" rel=\"bookmark\">\n                            Jimena Giudice, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Contribution of epigenetics dynamics in the regulation of alternative splicing in development and cell differentiation<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/James-S.-Hagood-MD.jpg\" alt=\"James S. Hagood MD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/James-S.-Hagood-MD.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jim-hagood-md\/\" rel=\"bookmark\">\n                            Jim Hagood, MD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We study epigenetic regulation of lung fibroblast phenotypes in the context of lung development and lung fibrosis.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Hathaway_image.jpeg\" alt=\"Nathan A. Hathaway, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Hathaway_image.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/nate-hathaway-phd\/\" rel=\"bookmark\">\n                            Nathan A. Hathaway, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our lab examines dynamic chromatin regulatory pathways in mammalian cells using novel chemical tools and inhibitors.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/ideraabdullah1.png\" alt=\"Folami Ideraabdullah, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/ideraabdullah1.png\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/folami-ideraabdullah-phd\/\" rel=\"bookmark\">\n                            Folami Ideraabdullah, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>DNA methylation epigenetic stability and heritability<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/Lindsey-I.-James-PhD.jpg\" alt=\"Lindsey I. James PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/Lindsey-I.-James-PhD.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/lindsey-i-james-phd\/\" rel=\"bookmark\">\n                            Lindsey I. James, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We are interested in modulating the activity of chromatin reader proteins with small molecule chemical probes or bivalent chemical degraders in order to open new avenues of research in the fields of chromatin and cancer biology and potentially translate to compounds of therapeutic value.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/Guochun-Jiang-PhD-731x1024.jpg\" alt=\"Guochun Jiang PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/Guochun-Jiang-PhD-731x1024.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/guochun-jiang-phd\/\" rel=\"bookmark\">\n                            Guochun Jiang, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We study epigenetic regulation of HIV transcription and latency in CD4+ T cells as well as non-T cells, with a focus of protein crotonylation.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/06\/Raja_Jothi_UNC_headshot_3.jpg\" alt=\"Raja Jothi, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/06\/Raja_Jothi_UNC_headshot_3.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/raja-jothi-phd\/\" rel=\"bookmark\">\n                            Raja Jothi, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Jothi lab is focused on mechanistic understanding of how transcription factors and chromatin remodeling complexes regulate gene expression programs controlling cell fate decisions during normal development and cancer.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Kim.jpeg\" alt=\"William Y. Kim, MD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Kim.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/billy-kim\/\" rel=\"bookmark\">\n                            William Y. Kim, MD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p><span>The Kim Lab is focused on understanding the genetic and epigenetic events involved in the initiation and progression of renal cell carcinoma (RCC) and bladder cancer.&#160; <\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/01\/Wonho_picture-751x1024.jpeg\" alt=\"Wonho Kim, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/01\/Wonho_picture-751x1024.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/wonho-kim-phd\/\" rel=\"bookmark\">\n                            Wonho Kim, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We try to understand the mechanism by which chromatin folding is regulated and how it affects gene transcription.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Legant_Headshot_Cropped.tif\" alt=\"Wesley Legant, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Legant_Headshot_Cropped.tif\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/wesley-legant-phd-2\/\" rel=\"bookmark\">\n                            Wesley Legant, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our lab uses advanced imaging approaches and biophysical modeling to study chromatin structure and dynamics.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Pengda-Liu.jpg\" alt=\"Pengda Liu, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Pengda-Liu.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/pengda-liu-phd\/\" rel=\"bookmark\">\n                            Pengda Liu, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We are interested in understanding how dysregulation of cancer signaling leads to tumorigenesis, including but not limited to, how E3 ubiquitin ligases recognize epigenetic markers using their PHD, WD40 or RING domains to control transcription and genome stability.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/maddox-paul-200X250.jpg\" alt=\"Paul S. Maddox, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/maddox-paul-200X250.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/paul-s-maddox\/\" rel=\"bookmark\">\n                            Paul S. Maddox, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We study the epigenetics of cell division using high-resolution imaging<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/margolis.jpeg\" alt=\"David Margolis, MD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/margolis.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/david-margolis-phd\/\" rel=\"bookmark\">\n                            David Margolis, MD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The overall goal of our laboratory is to obtain new insights into the host-virus interaction, particularly in HIV infection, and translate discoveries in molecular biology and virology to the clinic to aid in the treatment of HIV infection<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/marzluff-william-200X250.jpg\" alt=\"William F. Marzluff, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/marzluff-william-200X250.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/william-marzluff-phd\/\" rel=\"bookmark\">\n                            William F. Marzluff, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Regulation of histone gene expression balancing variant and canonical histones<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Matera.jpg\" alt=\"A. Greg Matera, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Matera.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/greg-matera-phd\/\" rel=\"bookmark\">\n                            A. Greg Matera, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Epigenetic regulation of gene expression<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/mckay-daniel-200X250.jpg\" alt=\"Daniel J. McKay, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/mckay-daniel-200X250.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/daniel-j-mckay-phd\/\" rel=\"bookmark\">\n                            Daniel J. McKay, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>genomics of gene regulation in development<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/Justin-Milner-PhD-683x1024.jpg\" alt=\"Justin Milner, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2021\/06\/Justin-Milner-PhD-683x1024.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/justin-milner-phd\/\" rel=\"bookmark\">\n                            Justin Milner                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We are interested in exploring the epigenetic and transcriptional mechanisms regulating T cell activity during infection and cancer, especially in the context of immunotherapies.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/mohlke_2011_mid.jpg\" alt=\"Karen L. Mohlke, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/mohlke_2011_mid.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/karen-l-mohlke-phd\/\" rel=\"bookmark\">\n                            Karen L. Mohlke, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p><span style=\"color: black; \">We identify genetic variants that influence chromatin structure and complex metabolic traits such as diabetes and obesity<\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/03\/john-1024x1024.jpeg\" alt=\"John P. Morris IV\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/03\/john-1024x1024.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/john-pacheco-morris-iv\/\" rel=\"bookmark\">\n                            John P. Morris IV                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Morris Lab studies epigenetic and genomic mechanisms that connect cancer driver mutations to cell fate transitions during tumor development.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Phanstiel1.jpg\" alt=\"Douglas H. Phanstiel, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Phanstiel1.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/douglas-h-phanstiel\/\" rel=\"bookmark\">\n                            Douglas H. Phanstiel, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p><span style=\"color: black; \">We use a combination of genomics, proteomics, genome editing, and bioinformatics to characterize and functionally interrogate DNA looping during monocyte differentiation.<\/span><\/p>\n<p>&#160;<\/p>\n<p>&#160;<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2024\/07\/KevinPruitt_1-1007x1024.jpg\" alt=\"Kevin Pruitt, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2024\/07\/KevinPruitt_1-1007x1024.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/kevin-pruitt-phd\/\" rel=\"bookmark\">\n                            Kevin Pruitt, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Pruitt lab is interested in defining how DNA methylation readers are regulated and contribute to cancer-linked immunosuppression. Second, we are exploring how Dishevelled proteins, which are master regulators of Wnt signaling, impact the epigenome.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Qian.jpg\" alt=\"Li Qian, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Qian.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/li-qian-phd\/\" rel=\"bookmark\">\n                            Li Qian, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Epigenetic mechanisms of direct cardiac reprogramming<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2019\/11\/Raab_Jesse.jpg\" alt=\"Jesse Raab, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2019\/11\/Raab_Jesse.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jesse-raab-phd\/\" rel=\"bookmark\">\n                            Jesse Raab, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our lab is interested in how changes to the composition of chromatin remodeling complexes are regulated, how their disruption affects their function, and contributes to disease.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Jeremy-Rich-Headshot.jpg\" alt=\"Jeremy Rich, MD, MHS, MBA\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Jeremy-Rich-Headshot.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jeremy-rich-md-mhs-mba\/\" rel=\"bookmark\">\n                            Jeremy Rich, MD, MHS, MBA                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p><span data-olk-copy-source=\"MessageBody\">Dr. Rich\u2019s Laboratory identifies novel therapeutic paradigms in the treatment of advanced cancers, primarily malignant brain tumors, through the prism of stem cell biology to identify core regulatory pathways amenable to pharmacologic targeting.<\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/06\/A7591889-EF01-47D2-8D2B-FFAF434A0EDD-776x1024.jpeg\" alt=\"Karl Shpargel, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2023\/06\/A7591889-EF01-47D2-8D2B-FFAF434A0EDD-776x1024.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/karl-shpargel-ph-d\/\" rel=\"bookmark\">\n                            Karl Shpargel, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p style=\"font-weight: 400\">The Shpargel laboratory studies the coordination of histone-modifying enzymes in regulating chromatin structure, enhancer activation, and transcription\u00a0during development with relevance to human disorders.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/jstein-image.jpg\" alt=\"Jason Stein, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/jstein-image.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jason-stein-ph-d\/\" rel=\"bookmark\">\n                            Jason Stein, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p style=\"margin: 0in 0in 0pt; \"><span style=\"color: black; \">We identify genetic variation that influences chromatin structure during the development of the human brain.<\/span><\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/08\/Ageliki-Tsagaratou-005.jpg\" alt=\"Ageliki Tsagaratou, PhD \" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/08\/Ageliki-Tsagaratou-005.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/ageliki-tsagaratou-phd\/\" rel=\"bookmark\">\n                            Ageliki Tsagaratou, PhD                         <\/a>\n                                    <\/h2> \n                \n                                                                    <p><span style=\"color: black;font-family: 'Calibri',sans-serif\"><span style=\"font-size: medium\">Epigenetic and transcriptional regulation in T cell differentiation, function and disease.\u00a0<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Wade02.jpeg\" alt=\"Paul A. Wade, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Wade02.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/paul-wade-phd\/\" rel=\"bookmark\">\n                            Paul A. Wade, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We study chromatin marks (with emphasis on DNA methylation and histone modification), the systems that read, write and modify these marks, and their impact on biological outcomes.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Waters.png\" alt=\"Marcey Waters, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Waters.png\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/marcey-waters-phd\/\" rel=\"bookmark\">\n                            Marcey Waters, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Waters group is developing novel sensing methodology for methylated Lys and Arg.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2024\/09\/WattsJ21_1405krev-683x1024.jpg\" alt=\"Jason Watts, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2024\/09\/WattsJ21_1405krev-683x1024.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jason-watts\/\" rel=\"bookmark\">\n                            Jason Watts, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>We study how nucleic acid structure and chromatin environment influence RNA polymerase pausing in renal and other human diseases.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Williams_121214.jpeg\" alt=\"David C. Williams, Jr., MD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/02\/Williams_121214.jpeg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/david-williams-phd\/\" rel=\"bookmark\">\n                            David C. Williams, Jr., MD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>My laboratory uses biophysical and structural analyses to study the methyl-cytosine binding domain family of proteins and the NuRD chromatin remodeling complex.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Profile-Pic-1024x683.jpg\" alt=\"Jie Xu, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2026\/01\/Profile-Pic-1024x683.jpg\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/jie-xu-phd\/\" rel=\"bookmark\">\n                            Jie Xu, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>The Xu lab develops single-cell technologies to track how altered epigenetic regulation and transcriptional programs jointly evolve in heterogenous cells during cancer progression.<\/p>\n                            <\/div>\n        <\/article>\n\n            <article class=\"row post entry\">\n            <div class=\"directory-gallery-thumbnail\">\n                                                                                                \t\t\n                    <div class=\"upd-image\">\n                        <img loading=\"lazy\" decoding=\"async\" class=\"upd_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/11\/Zannas.png\" alt=\"Anthony S. Zannas, MD, PhD\" height=\"160\" width=\"120\" \/>\n                        <img decoding=\"async\" class=\"print_img\" src=\"https:\/\/www.med.unc.edu\/epigenetics\/wp-content\/uploads\/sites\/586\/2018\/11\/Zannas.png\" alt=\"\" \/>\n                    <\/div>\t\t\t\t\t\t\t\t\t\n                            <\/div>\n            <div class=\"directory-gallery-content\">\n                <h2 class=\"entry-title\">                                            <a href=\"https:\/\/www.med.unc.edu\/epigenetics\/directory\/zannas-anthony\/\" rel=\"bookmark\">\n                            Anthony S. Zannas, MD, PhD                        <\/a>\n                                    <\/h2> \n                \n                                                                    <p>Our lab seeks to uncover the epigenetic mechanisms linking psychosocial stress with disease risk<\/p>\n                            <\/div>\n        <\/article>\n\n    \n    <script type=\"text\/javascript\">\n        (function($){\n            var entries = $('.entry-content');\n                entries.each(function(index, entry ){\n                    if( $(entry).find('.post-author').length === 0 ) {\n                        $(entry).parents('article.post.entry').css('min-height', '110px');\n                    }\n                });\n        })(jQuery);\n    <\/script>\n\n<\/div>\n\n\n","protected":false},"excerpt":{"rendered":"<p>Meet the investigators involved with epigenetics research: Leadership Members<\/p>\n","protected":false},"author":11566,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2213","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - 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