Hirsch Lab
The Hirsch lab investigates the use adeno-associated viral (AAV) vectors for therapeutic gene delivery and gene editing towards the treatment of several genetic diseases. At the mechanistic level, we seek to characterize the cellular response to the multi-functional AAV inverted terminal repeats in gene addition and gene editing strategies. Our preclinical programs are targeted at providing safe and effective gene therapy treatment options for ocular diseases of the cornea and retina. In addition, our technologies are also under investigation for the treatment of muscular dystrophies.
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