2018

  • Chai Z, Zhang X, Rigsbee KM, Wang M, Samulski RJ, Li C. Cryoprecipitate augments the global transduction of the adeno-associated virus serotype 9 after a systemic administration. J Control Release. 2018 Sep 28;286:415-424.
  • Junjiang Sun, Wenwei Shao, Xiaojing Chen, Elizabeth P. Merricks, Lauren Wimsey, Yasmina L. Abajas, Glenn P. Niemeyer, Clinton D. Lothrop, Paul E. Monahan, Richard J. Samulski, Timothy C. Nichols, Chengwen Li. An observational study from long-term AAV re-administration in two hemophilia dogs. Molecular Therapy: Methods & Clinical Development (2018), doi: 10.1016/j.omtm.2018.07.011.
  • Chai Z, Samulski RJ, Li C. Nab Escaping AAV Mutants Isolated from Mouse Muscles. Bio Protoc. 2018 May 5;8(9). pii: e2841. doi: 10.21769/BioProtoc.2841.
  • Shao W, Earley LF, Chai Z, Chen X, Sun J, He T, Deng M, Hirsch ML, Ting J, Samulski RJ, Li C. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction. JCI Insight. 2018 Jun 21;3(12). pii: 120474. doi: 10.1172/jci.insight.120474. [Epub ahead of print]
  • Zhang X, He T, Chai Z, Samulski RJ, Li C. Blood-brain barrier shuttle peptides enhance AAV transduction in the brain after systemic administration. Biomaterials. 2018 May 26;176:71-83
  • Pei X, He T, Hall NE, Gerber D, Samulski RJ, Li C. AAV8 virions hijack serum proteins to increase hepatocyte binding for transduction enhancement. Virology. 2018 May;518:95-102.
  • Pei X, Earley LF, He Y, Chen X, Hall NE, Samulski RJ, Li C. Efficient Capsid Antigen Presentation From Adeno-Associated Virus Empty Virions In Vivo. Front Immunol. 2018 Apr 19;9:844
  • Shao W, Chen X, Samulski RJ, Hirsch ML, Li C. Inhibition of antigen presentation during AAV gene therapy using virus peptides. Hum Mol Genet. 2018 Feb 15;27(4):601-613.
  • Sun J, Yuan Z, Abajas YL, Szollosi DE, Hu G, Hua B, Xiao X, Li C. A Retrospective Study of the Cytokine Profile Changes in Mice with FVIII Inhibitor Development After Adeno-Associated Virus-Mediated Gene Therapy in a Hemophilia A Mouse Model. Hum Gene Ther. 2018 Mar;29(3):381-389.

2017

  • Chai Z, Sun J, Rigsbee KM, Wang M, Jude Samulski R, Li C. Application of polyploid adeno-associated virus vectors for transduction enhancement and neutralizing antibody evasion. J Control Release. 2017 Sep 28;262:348-356.
  • Sanchez AC, Li C, Andrews B, Asenjo JA, Samulski RJ. AAV Gene Therapy for Alcoholism: Inhibition of Mitochondrial Aldehyde Dehydrogenase Enzyme Expression in Hepatoma Cells. Hum Gene Ther. 2017 Sep;28(9):717-725.
  • Sun J, Hua B, Samulski RJ, Li C. Gene delivery of activated Factor VII Using Alternative AAV Serotype Improves Hemostasis in Hemophiliac Mice with FVIII Inhibitors and AAV Neutralizing antibodies. Hum Gene Ther. 2017 Aug;28(8):654-666.
  • Manzoor F, Johnson MC, Li C, Samulski RJ, Wang B, Tisch R. β-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice. Eur J Immunol. 2017 Jan;47(1):144-154.
  • Wang M, Sun J, Crosby A, Woodard K, Hirsch ML, Samulski RJ, Li C. Direct interaction of human serum proteins with AAV virions to enhance AAV transduction: immediate impact on clinical applications. Gene Ther. 2017 Jan;24(1):49-59.