{"id":2556,"date":"2018-03-29T10:12:34","date_gmt":"2018-03-29T14:12:34","guid":{"rendered":"https:\/\/med.sites.unc.edu\/genetics\/berglab\/?p=2556"},"modified":"2018-03-29T10:12:34","modified_gmt":"2018-03-29T14:12:34","slug":"genome-scale-sequencing-now-allows-us-to-generate-massive-amounts-of-genetic-variant-data-that-facilitates-the-discovery-of-new-disease-associated-genes","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/berglab\/genome-scale-sequencing-now-allows-us-to-generate-massive-amounts-of-genetic-variant-data-that-facilitates-the-discovery-of-new-disease-associated-genes\/","title":{"rendered":"Genome-scale sequencing now allows us to generate massive amounts of genetic variant data that facilitates the discovery of new disease-associated genes"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-2520\" src=\"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree-300x140.jpg\" alt=\"\" width=\"300\" height=\"140\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree-300x140.jpg 300w, https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree-150x70.jpg 150w, https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree.jpg 600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>Yet for many disorders we still only understand a fraction of the genes that (when mutated) cause disease.\u00a0 Our lab studies individuals and families with likely hereditary cancer susceptibility in order to discover new candidate genes for monogenic forms of hereditary breast cancer, polyposis, and other cancer types.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Yet for many disorders we still only understand a fraction of the genes that (when mutated) cause disease.\u00a0 Our lab studies individuals and families with likely hereditary cancer susceptibility in order to discover new candidate genes for monogenic forms of hereditary breast cancer, polyposis, and other cancer types.<\/p>\n","protected":false},"author":3206,"featured_media":2520,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2556","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree-300x140.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-content\/uploads\/sites\/617\/2018\/03\/pedigree-150x70.jpg","featured_image_alt":"","category_details":[{"name":"Uncategorized","link":"https:\/\/www.med.unc.edu\/genetics\/berglab\/category\/uncategorized\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/posts\/2556","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/users\/3206"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/comments?post=2556"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/posts\/2556\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/media\/2520"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/media?parent=2556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/categories?post=2556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/berglab\/wp-json\/wp\/v2\/tags?post=2556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}