{"id":11159,"date":"2021-11-29T08:03:18","date_gmt":"2021-11-29T13:03:18","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=11159"},"modified":"2021-11-29T08:03:18","modified_gmt":"2021-11-29T13:03:18","slug":"department-of-genetics-publications-november-14th-27th-2021","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-november-14th-27th-2021\/","title":{"rendered":"Department of Genetics Publications November 14th \u2013 27th 2021"},"content":{"rendered":"

\"UNCDepartment of Genetics faculty, postdocs, students and collaborators published 16 papers during November 14th<\/sup> \u2013 27th<\/sup> 2021.<\/p>\n

Widespread introgression across a phylogeny of 155 Drosophila genomes.\u00a0<\/a><\/p>\n

Suvorov A<\/strong>, Kim BY, Wang J<\/strong>, Armstrong EE, Peede D, D’Agostino ERR, Price DK, Waddell P, Lang M, Courtier-Orgogozo V, David JR, Petrov D, Matute DR, Schrider DR<\/strong>, Comeault AA.<\/p>\n

Curr Biol. 2021 Nov 12:S0960-9822(21)01496-2. doi: 10.1016\/j.cub.2021.10.052. Online ahead of print.<\/p>\n

PMID:\u00a034788634<\/p>\n

 <\/p>\n

Full title: A large-scale transcriptome-wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine-mapping.\u00a0<\/a><\/p>\n

Tapia AL, Rowland BT, Rosen JD, Preuss M, Young K, Graff M, Choquet H, Couper DJ, Buyske S, Bien SA, Jorgenson E, Kooperberg C, Loos RJF, Morrison AC, North KE, Yu B, Reiner AP, Li Y, Raffield LM.<\/strong><\/p>\n

Genet Epidemiol. 2021 Nov 15. doi: 10.1002\/gepi.22436. Online ahead of print.<\/p>\n

PMID:\u00a034779012<\/p>\n

 <\/p>\n

Mammalian SWI\/SNF chromatin remodeler is essential for reductional meiosis in males.\u00a0<\/a><\/p>\n

Menon DU,<\/strong> Kirsanov O, Geyer CB, Magnuson T.<\/strong><\/p>\n

Nat Commun. 2021 Nov 12;12(1):6581. doi: 10.1038\/s41467-021-26828-1.<\/p>\n

PMID:\u00a034772938\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation.\u00a0<\/a><\/p>\n

Perryman A, Speen AM, Kim HH, Hoffman JR, Clapp PW, Rivera Martin W, Snouwaert JN,<\/strong> Koller BH<\/strong>, Porter NA, Jaspers I.<\/p>\n

Am J Respir Cell Mol Biol. 2021 Nov;65(5):500-512. doi: 10.1165\/rcmb.2021-0032OC.<\/p>\n

PMID:\u00a034126877<\/p>\n

 <\/p>\n

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.\u00a0<\/a><\/p>\n

Wu P, Moon JY, Daghlas I, Franco G, Porneala BC, Ahmadizar F, Richardson TG, Isaksen JL, Hindy G, Yao J, Sitlani CM, Raffield LM,<\/strong> Yanek LR, Feitosa MF, Cuadrat RRC, Qi Q, Arfan Ikram M, Ellervik C, Ericson U, Goodarzi MO, Brody JA, Lange L, Mercader JM, Vaidya D, An P, Schulze MB, Masana L, Ghanbari M, Olesen MS, Cai J, Guo X, Floyd JS, J\u00e4ger S, Province MA, Kalyani RR, Psaty BM, Orho-Melander M, Ridker PM, Kanters JK, Uitterlinden A, Davey Smith G, Gill D, Kaplan RC, Kavousi M, Raghavan S, Chasman DI, Rotter JI, Meigs JB, Florez JC, Dupuis J, Liu CT, Merino J.<\/p>\n

Diabetes Care. 2021 Nov 17:dc211284. doi: 10.2337\/dc21-1284. Online ahead of print.<\/p>\n

PMID:\u00a034789503<\/p>\n

 <\/p>\n

The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum.\u00a0<\/a><\/p>\n

Mahjani B, Klei L, Mattheisen M, Halvorsen MW<\/strong>, Reichenberg A, Roeder K, Pedersen NL, Boberg J, de Schipper E, Bulik CM, Land\u00e9n M, Fund\u00edn B, Mataix-Cols D, Sandin S, Hultman CM, Crowley JJ<\/strong>, Buxbaum JD, R\u00fcck C, Devlin B, Grice DE.<\/p>\n

Am J Psychiatry. 2021 Nov 18:appiajp202121010101. doi: 10.1176\/appi.ajp.2021.21010101. Online ahead of print.<\/p>\n

PMID:\u00a034789012<\/p>\n

 <\/p>\n

ZHX2 promotes HIF1\u03b1 oncogenic signaling in triple-negative breast cancer.\u00a0<\/a><\/p>\n

Fang W, Liao C, Shi R, Simon JM<\/strong>, Ptacek TS, Zurlo G, Ye Y, Han L, Fan C, Bao L, Ortiz CL, Lin HR, Manocha U, Luo W, Peng Y, Kim WY<\/strong>, Yang LW, Zhang Q.<\/p>\n

Elife. 2021 Nov 15;10:e70412. doi: 10.7554\/eLife.70412. Online ahead of print.<\/p>\n

PMID:\u00a034779768<\/p>\n

 <\/p>\n

VE-Cadherin Is Required for Cardiac Lymphatic Maintenance and Signaling.\u00a0<\/a><\/p>\n

Harris NR, Nielsen NR, Pawlak JB, Aghajanian A, Rangarajan K, Serafin DS, Farber G, Dy DM, Nelson-Maney NP, Xu W, Ratra D, Hurr SH, Qian L, Scallan J, Caron KM<\/strong>.<\/p>\n

Circ Res. 2021 Nov 18. doi: 10.1161\/CIRCRESAHA.121.318852. Online ahead of print.<\/p>\n

PMID:\u00a034789016<\/p>\n

 <\/p>\n

RAF1 amplification: an exemplar of MAPK pathway activation in urothelial carcinoma.\u00a0<\/a><\/p>\n

Clark-Garvey S, Kim WY.<\/strong><\/p>\n

J Clin Invest. 2021 Nov 15;131(22):e154095. doi: 10.1172\/JCI154095.<\/p>\n

PMID:\u00a034779406<\/p>\n

 <\/p>\n

Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits.\u00a0<\/a><\/p>\n

Orchard P, Manickam N, Ventresca C, Vadlamudi S<\/strong>, Varshney A, Rai V, Kaplan J, Lalancette C, Mohlke KL<\/strong>, Gallagher K, Burant CF, Parker SCJ.<\/p>\n

Genome Res. 2021 Nov 23. doi: 10.1101\/gr.268482.120. Online ahead of print.<\/p>\n

PMID:\u00a034815310<\/p>\n

 <\/p>\n

The structure of the human cell cycle.\u00a0<\/a><\/p>\n

Stallaert W, Kedziora KM, Taylor CD,<\/strong> Zikry TM, Ranek JS, Sobon HK, Taylor SR, Young CL,<\/strong> Cook JG, Purvis JE.<\/strong><\/p>\n

Cell Syst. 2021 Nov 17:S2405-4712(21)00418-X. doi: 10.1016\/j.cels.2021.10.007. Online ahead of print.<\/p>\n

PMID:\u00a034800361<\/p>\n

 <\/p>\n

SMNN: batch effect correction for single-cell RNA-seq data via supervised mutual nearest neighbor detection.\u00a0<\/a><\/p>\n

Yang Y, <\/strong>Li G, Qian H, Wilhelmsen KC,<\/strong> Shen Y, Li Y.<\/strong><\/p>\n

Brief Bioinform. 2021 May 20;22(3):bbaa097. doi: 10.1093\/bib\/bbaa097.<\/p>\n

PMID:\u00a032591778\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Genome-wide cancer-specific chromatin accessibility patterns derived from archival processed xenograft tumors.\u00a0<\/a><\/p>\n

Marcel SS,<\/strong> Quimby AL, Noel MP, Jaimes OC, Mehrab-Mohseni M, Ashur SA, Velasco B, Tsuruta JK, Kasoji SK, Santos CM, Dayton PA, Parker JS, Davis IJ, <\/strong>Pattenden SG.<\/p>\n

Genome Res. 2021 Nov 23. doi: 10.1101\/gr.275219.121. Online ahead of print.<\/p>\n

PMID:\u00a034815311<\/p>\n

 <\/p>\n

Molecular and clinical characterization of postpartum-associated breast cancer in the Carolina Breast Cancer Study Phase I-III, 1993-2013.\u00a0<\/a><\/p>\n

Vohra SN, Walens A, Hamilton AM, Sherman ME, Schedin P, Nichols HB, Reeder-Hayes KE, Olshan AF, Love MI<\/strong>, Troester MA.<\/p>\n

Cancer Epidemiol Biomarkers Prev. 2021 Nov 22:cebp.0940.2021. doi: 10.1158\/1055-9965.EPI-21-0940. Online ahead of print.<\/p>\n

PMID:\u00a034810211<\/p>\n

 <\/p>\n

The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders.\u00a0<\/a><\/p>\n

Alkelai A, Greenbaum L, Docherty AR, Shabalin AA, Povysil G, Malakar A, Hughes D, Delaney SL, Peabody EP, McNamara J, Gelfman S, Baugh EH, Zoghbi AW, Harms MB, Hwang HS, Grossman-Jonish A, Aggarwal V, Heinzen EL<\/strong>, Jobanputra V, Pulver AE, Lerer B, Goldstein DB.<\/p>\n

Mol Psychiatry. 2021 Nov 19. doi: 10.1038\/s41380-021-01383-9. Online ahead of print.<\/p>\n

PMID:\u00a034799694<\/p>\n

 <\/p>\n

Single-Cell RNA Sequencing Reveals Endothelial Cell Transcriptome Heterogeneity Under Homeostatic Laminar Flow.\u00a0<\/a><\/p>\n

Liu Z, Ruter DL, Quigley K, Tanke NT, Jiang Y<\/strong>, Bautch VL.<\/p>\n

Arterioscler Thromb Vasc Biol. 2021 Oct;41(10):2575-2584. doi: 10.1161\/ATVBAHA.121.316797. Epub 2021 Aug 26.<\/p>\n

PMID:\u00a034433297\u00a0Free PMC article.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published 16 papers during November 14th \u2013 27th 2021.<\/p>\n","protected":false},"author":28418,"featured_media":6539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[78,57,270,58,274,31,60,122,113,56,34,53,299,276,36,63,30,27,84,306,96,130,133,402,102,400,401,403,28,191,197,156,135,404],"class_list":["post-11159","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-caron","tag-crowley","tag-davis-ij","tag-halvorsen","tag-heinzen","tag-jiang","tag-kedziora","tag-kim","tag-koller","tag-li","tag-love","tag-magnuson","tag-marcel","tag-menon","tag-mohlke","tag-parker","tag-publications","tag-purvis","tag-raffield","tag-ranek","tag-schrider","tag-simon","tag-snouwaert","tag-sobon","tag-stallaert","tag-suvorov","tag-taylor","tag-taylor-sr","tag-unc-genetics","tag-vadlamudi","tag-wang","tag-wilhelmsen","tag-yang","tag-young-cl","odd"],"acf":[],"yoast_head":"\nDepartment 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