{"id":13575,"date":"2024-01-25T10:48:11","date_gmt":"2024-01-25T15:48:11","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=13575"},"modified":"2024-01-25T10:48:11","modified_gmt":"2024-01-25T15:48:11","slug":"dr-jeremy-purvis-awarded-new-r01-grant-from-nci","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/dr-jeremy-purvis-awarded-new-r01-grant-from-nci\/","title":{"rendered":"Dr. Jeremy Purvis Awarded New R01 Grant from NCI"},"content":{"rendered":"
\"Jeremy
Jeremy Purvis, PhD (Professor, Department of Genetics)<\/figcaption><\/figure>\n

Jeremy Purvis, PhD (Professor, Department of Genetics) has been awarded a new R01 grant for his project titled \u201cCell cycle paths as a framework for understanding drug resistance in tumor cell subpopulations\u201d from the National Cancer Institute.<\/p>\n

The goal of this project is to investigate variability in tumor cell cycle progression at the single-cell level and to apply this fundamental knowledge to understand how ER+\/HER2- tumor cells resist palbociclib-induced cell cycle arrest.\u00a0 Overall, this project will build a molecular understanding of the heterogeneity in cell cycle behaviors that leads to fractional arrest in ER+\/HER2- tumors, paving the way for the development of next-generation systems biomarkers that capture the unique cell cycle behaviors and drug sensitivities in other cancer types.<\/p>\n","protected":false},"excerpt":{"rendered":"

Jeremy Purvis, PhD (Professor, Department of Genetics) has been awarded a new R01 grant for his project titled \u201cCell cycle paths as a framework for understanding drug resistance in tumor cell subpopulations\u201d from the National Cancer Institute.<\/p>\n","protected":false},"author":28418,"featured_media":6523,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[27],"class_list":["post-13575","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-purvis","odd"],"acf":[],"yoast_head":"\nDr. Jeremy Purvis Awarded New R01 Grant from NCI | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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