{"id":13873,"date":"2024-04-29T10:17:53","date_gmt":"2024-04-29T14:17:53","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=13873"},"modified":"2024-04-29T10:17:53","modified_gmt":"2024-04-29T14:17:53","slug":"department-of-genetics-publications-for-april-14th-27th-2024","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-april-14th-27th-2024\/","title":{"rendered":"Department of Genetics Publications for April 14th – 27th, 2024"},"content":{"rendered":"

\"UNCDepartment of Genetics faculty, postdocs, students and collaborators published 12 papers during April 14th – 27th, 2024.<\/p>\n

 <\/p>\n

MagicalRsq-X: A cross-cohort transferable genotype imputation quality metric.\u00a0<\/a><\/p>\n

Sun Q,<\/strong> Yang Y, Rosen JD, Chen J, Li X, Guan W,<\/strong> Jiang MZ, Wen J,<\/strong> Pace RG, Blackman SM, Bamshad MJ, Gibson RL, Cutting GR, O’Neal WK,<\/strong> Knowles MR, Kooperberg C, Reiner AP, Raffield LM<\/strong>, Carson AP, Rich SS, Rotter JI, Loos RJF, Kenny E, Jaeger BC, Min YI, Fuchsberger C, Li Y.<\/strong><\/p>\n

Am J Hum Genet. 2024 Apr 9:S0002-9297(24)00116-2. doi: 10.1016\/j.ajhg.2024.04.001. Online ahead of print.<\/p>\n

PMID:\u00a038636510<\/p>\n

 <\/p>\n

CoVar: A generalizable machine learning approach to identify the coordinated regulators driving variational gene expression.\u00a0<\/a><\/p>\n

Roy S, Sheikh SZ, Furey TS.<\/strong><\/p>\n

PLoS Comput Biol. 2024 Apr 17;20(4):e1012016. doi: 10.1371\/journal.pcbi.1012016. Online ahead of print.<\/p>\n

PMID:\u00a038630807<\/p>\n

 <\/p>\n

CHD4 and SMYD1 repress common transcriptional programs in the developing heart.\u00a0<\/a><\/p>\n

Shi W,<\/strong> Wasson LK, Dorr KM, Robbe ZL, Wilczewski CM,<\/strong> Hepperla AJ<\/strong>, Davis IJ, Seidman CE, Seidman JG, Conlon FL.<\/strong><\/p>\n

Development. 2024 Apr 15:dev.202505. doi: 10.1242\/dev.202505. Online ahead of print.<\/p>\n

PMID:\u00a038619323<\/p>\n

 <\/p>\n

Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis.\u00a0<\/a><\/p>\n

Zhang C, Yu M, Hepperla AJ<\/strong>, Zhang Z, Raj R, Zhong H, Zhou J, Hu L, Fang J, Liu H, Liang Q, Jia L, Liao C, Xi S, Simon JM<\/strong>, Xu K, Liu Z, Nam Y, Kapur P, Zhang Q.<\/p>\n

J Clin Invest. 2024 Apr 15;134(8):e175703. doi: 10.1172\/JCI175703.<\/p>\n

PMID:\u00a038618952\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

MutL\u03b1 suppresses error-prone DNA mismatch repair and preferentially protects noncoding DNA from mutations.\u00a0<\/a><\/p>\n

Kadyrova LY, Mieczkowski PA<\/strong>, Kadyrov FA.<\/p>\n

bioRxiv [Preprint]. 2024 Apr 2:2024.04.01.587563. doi: 10.1101\/2024.04.01.587563.<\/p>\n

PMID:\u00a038617288\u00a0Free PMC article.<\/strong>\u00a0Preprint.<\/p>\n

 <\/p>\n

Disentangling sex-dependent effects of APOE on diverse trajectories of cognitive decline in Alzheimer’s disease.\u00a0<\/a><\/p>\n

Ma H, Shi Z, Kim M, Liu B, Smith PJ, Liu Y<\/strong>, Wu G; Alzheimer’s Disease Neuroimaging Initiative (ADNI).<\/p>\n

Neuroimage. 2024 Apr 12;292:120609. doi: 10.1016\/j.neuroimage.2024.120609. Online ahead of print.<\/p>\n

PMID:\u00a038614371<\/p>\n

 <\/p>\n

Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification.\u00a0<\/a><\/p>\n

Ryu J, Barkal S, Yu T, Jankowiak M, Zhou Y, Francoeur M, Phan QV, Li Z, Tognon M, Brown L, Love MI<\/strong>, Bhat V, Lettre G, Ascher DB, Cassa CA, Sherwood RI, Pinello L.<\/p>\n

Nat Genet. 2024 Apr 24. doi: 10.1038\/s41588-024-01726-6. Online ahead of print.<\/p>\n

PMID:\u00a038658794<\/p>\n

 <\/p>\n

Single-cell analysis revealing the metabolic landscape of prostate cancer.\u00a0<\/a><\/p>\n

Wang J, Ding HK, Xu HJ, Hu DK, Hankey W<\/strong>, Chen L, Xiao J, Liang CZ, Zhao B, Xu LF.<\/p>\n

Asian J Androl. 2024 Apr 23. doi: 10.4103\/aja20243. Online ahead of print.<\/p>\n

PMID:\u00a038657119<\/p>\n

 <\/p>\n

Mapping of susceptibility loci for Ebola virus pathogenesis in mice.\u00a0<\/a><\/p>\n

Sch\u00e4fer A, Marzi A, Furuyama W, Catanzaro NJ, Nguyen C, Haddock E, Feldmann F, Meade-White K, Thomas T, Hubbard ML, Gully KL, Leist SR, Hock P, Bell TA<\/strong>, De la Cruz GE, Midkiff BR, Martinez DR, Shaw GD, Miller DR,<\/strong> Vernon MJ<\/strong>, Graham RL, Cowley DO<\/strong>, Montgomery SA, Schughart K, de Villena FPM<\/strong>, Wilkerson GK, Ferris MT<\/strong>, Feldmann H, Baric RS.<\/p>\n

Cell Rep. 2024 Apr 21;43(5):114127. doi: 10.1016\/j.celrep.2024.114127. Online ahead of print.<\/p>\n

PMID:\u00a038652660<\/p>\n

 <\/p>\n

Genomics of severe and treatment-resistant obsessive-compulsive disorder treated with deep brain stimulation: A preliminary investigation.\u00a0<\/a><\/p>\n

Chen LL, Naesstr\u00f6m M, Halvorsen M<\/strong>, Fytagoridis A, Crowley SB, Mataix-Cols D, R\u00fcck C, Crowley JJ,<\/strong> Pascal D.<\/p>\n

Am J Med Genet B Neuropsychiatr Genet. 2024 Apr 22:e32983. doi: 10.1002\/ajmg.b.32983. Online ahead of print.<\/p>\n

PMID:\u00a038650085<\/p>\n

 <\/p>\n

Dysregulation of innate immune signaling in animal models of spinal muscular atrophy.\u00a0<\/a><\/p>\n

Garcia EL, Steiner RE, Raimer AC<\/strong>, Herring LE, Matera AG<\/strong>, Spring AM.<\/p>\n

BMC Biol. 2024 Apr 25;22(1):94. doi: 10.1186\/s12915-024-01888-z.<\/p>\n

PMID:\u00a038664795<\/p>\n

 <\/p>\n

Multi-response Regression for Block-missing Multi-modal Data without Imputation.\u00a0<\/a><\/p>\n

Wang H, Li Q, Liu Y.<\/strong><\/p>\n

Stat Sin. 2024 Apr;34(2):527-546. doi: 10.5705\/ss.202021.0170.<\/p>\n

PMID:\u00a038655129\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published 12 papers during April 14th – 27th 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