{"id":14457,"date":"2024-10-17T16:53:40","date_gmt":"2024-10-17T20:53:40","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=14457"},"modified":"2024-10-17T16:53:40","modified_gmt":"2024-10-17T20:53:40","slug":"department-of-genetics-publications-for-september-29th-october-12th-2024","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-september-29th-october-12th-2024\/","title":{"rendered":"Department of Genetics Publications for September 29th – October 12th, 2024"},"content":{"rendered":"

\"UNCDepartment of Genetics faculty, postdocs, students and collaborators published 13 papers during September 29th – October 12th, 2024.<\/p>\n

TET proteins regulate\u00a0Drosha<\/em>\u00a0expression and impact microRNAs in iNKT cells.\u00a0<\/a><\/p>\n

Gioulbasani M, \u00c4ij\u00f6 T, Valenzuela JE, Bettes JB, Tsagaratou A.<\/strong><\/p>\n

Front Immunol. 2024 Sep 19;15:1440044. doi: 10.3389\/fimmu.2024.1440044. eCollection 2024.<\/p>\n

PMID:\u00a039364402\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms.\u00a0<\/a><\/p>\n

Zhou X, Wang Y, Dou Z, Delfanti G, Tsahouridis O, Pellegry CM, Zingarelli M, Atassi G, Woodcock MG, Casorati G, Dellabona P, Kim WY,<\/strong> Guo L, Savoldo B, Tsagaratou A<\/strong>, Milner JJ, Metelitsa LS, Dotti G.<\/p>\n

Nat Cancer. 2024 Oct 1. doi: 10.1038\/s43018-024-00830-0. Online ahead of print.<\/p>\n

PMID:\u00a039354225<\/p>\n

 <\/p>\n

Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations.\u00a0<\/a><\/p>\n

Liu S, Zhu J, Zhong H, Wu C, Xue H, Darst BF, Guo X, Durda P, Tracy RP, Liu Y, Johnson WC, Taylor KD, Manichaikul AW, Goodarzi MO, Gerszten RE, Clish CB, Chen YI, Highland H, Haiman CA, Gignoux CR, Lange L, Conti DV, Raffield LM<\/strong>, Wilkens L, Marchand LL, North KE, Young KL, Loos RJ, Buyske S, Matise T, Peters U, Kooperberg C, Reiner AP, Yu B, Boerwinkle E, Sun Q<\/strong>, Rooney MR, Echouffo-Tcheugui JB, Daviglus ML, Qi Q, Mancuso N, Li C, Deng Y, Manning A, Meigs JB, Rich SS, Rotter JI, Wu L.<\/p>\n

Diabetologia. 2024 Sep 30. doi: 10.1007\/s00125-024-06277-3. Online ahead of print.<\/p>\n

PMID:\u00a039349773<\/p>\n

 <\/p>\n

Stimulating Wnt signaling reveals context-dependent genetic effects on gene regulation in primary human neural progenitors.\u00a0<\/a><\/p>\n

Matoba N, Le BD, Valone JM, Wolter JM, Mory JT, Liang D, Ayg\u00fcn N, Broadaway KA, Bond ML,<\/strong> Mohlke KL<\/strong>, Zylka MJ, Love MI, Stein JL.<\/strong><\/p>\n

Nat Neurosci. 2024 Sep 30. doi: 10.1038\/s41593-024-01773-6. Online ahead of print.<\/p>\n

PMID:\u00a039349663<\/p>\n

 <\/p>\n

Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genome Production.\u00a0<\/a><\/p>\n

Levi LI, Madden EA, Boussier J, Erazo D, Sanders W, Vallet T, Bernhauerova V, Moorman NJ, Heise MT<\/strong>, Vignuzzi M.<\/p>\n

Microorganisms. 2024 Aug 29;12(9):1794. doi: 10.3390\/microorganisms12091794.<\/p>\n

PMID:\u00a039338469\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.\u00a0<\/a><\/p>\n

Hawkes G, Beaumont RN, Li Z, Mandla R, Li X<\/strong>, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN.<\/p>\n

Nat Commun. 2024 Oct 3;15(1):8549. doi: 10.1038\/s41467-024-52579-w.<\/p>\n

PMID:\u00a039362880<\/p>\n

 <\/p>\n

Epigenetic Regulation in Psychosomatics and Psychotherapy.\u00a0<\/a><\/p>\n

Kroflin K, Zannas AS.<\/strong><\/p>\n

Am J Psychother. 2024 Sep 30:appipsychotherapy20230061. doi: 10.1176\/appi.psychotherapy.20230061. Online ahead of print.<\/p>\n

PMID:\u00a039344301\u00a0Review.<\/p>\n

 <\/p>\n

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.\u00a0<\/a><\/p>\n

Wani AH, Katrinli S, Zhao X, Daskalakis NP, Zannas<\/strong> AS<\/strong>, Aiello AE, Baker DG, Boks MP, Brick LA, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes JP, Kessler RC, King AP, Koen N, Liberzon I, Lori A, Luykx JJ, Maihofer AX, Milberg W, Miller MW, Mufford MS, Nugent NR, Rauch S, Ressler KJ, Risbrough VB, Rutten BPF, Stein DJ, Stein MB, Ursano RJ, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Nievergelt CM, Logue MW, Smith AK, Uddin M.<\/p>\n

BMC Med Genomics. 2024 Sep 27;17(1):235. doi: 10.1186\/s12920-024-02002-6.<\/p>\n

PMID:\u00a039334086\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.\u00a0<\/a><\/p>\n

Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Tse EG, Stashko MA, Li K, Norris-Drouin JL, Herring LE, Mordant AL, Webb TS, Mills CA, Barker NK, Streblow ZJ, Perveen S, Arrowsmith CH, Cou\u00f1ago RM, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise MT<\/strong>, Willson TM, Popov KI, Pearce KH.<\/p>\n

Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2409166121. doi: 10.1073\/pnas.2409166121. Epub 2024 Oct 10.<\/p>\n

PMID:\u00a039388272<\/p>\n

 <\/p>\n

Rare variant contribution to the heritability of coronary artery disease.\u00a0<\/a><\/p>\n

Rocheleau G, Clarke SL, Auguste G, Hasbani NR, Morrison AC, Heath AS, Bielak LF, Iyer KR, Young EP, Stitziel NO, Jun G, Laurie C, Broome JG, Khan AT, Arnett DK, Becker LC, Bis JC, Boerwinkle E, Bowden DW, Carson AP, Ellinor PT, Fornage M, Franceschini N, Freedman BI, Heard-Costa NL, Hou L, Chen YI, Kenny EE, Kooperberg C, Kral BG, Loos RJF, Lutz SM, Manson JE, Martin LW, Mitchell BD, Nassir R, Palmer ND, Post WS, Preuss MH, Psaty BM, Raffield LM<\/strong>, Regan EA, Rich SS, Smith JA, Taylor KD, Yanek LR, Young KA; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Hilliard AT, Tcheandjieu C, Peyser PA, Vasan RS, Rotter JI, Miller CL, Assimes TL, de Vries PS, Do R.<\/p>\n

Nat Commun. 2024 Oct 9;15(1):8741. doi: 10.1038\/s41467-024-52939-6.<\/p>\n

PMID:\u00a039384761\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

A systematic framework for selecting gene-condition pairs for inclusion in newborn sequencing panels: Early Check implementation.\u00a0<\/a><\/p>\n

Cope HL, Milko LV, Jalazo ER<\/strong>, Crissman BG, Foreman AKM, Powell BC<\/strong>, deJong NA, Hunter JE, Boyea BL, Forsythe AN, Wheeler AC, Zimmerman RS, Suchy SF, Begtrup A, Langley KG, Monaghan KG, Kraczkowski C, Hruska KS, Kruszka P, Kucera KS, Berg JS, Powell CM<\/strong>, Peay HL.<\/p>\n

Genet Med. 2024 Oct 4:101290. doi: 10.1016\/j.gim.2024.101290. Online ahead of print.<\/p>\n

PMID:\u00a039375994<\/p>\n

 <\/p>\n

Genome-wide association study meta-analysis of 9,619 cases with tic disorders.\u00a0<\/a><\/p>\n

Strom NI, Halvorsen MW<\/strong>, Grove J, \u00c1sbj\u00f6rnsd\u00f3ttir B, Lu\u00f0v\u00edgsson P, Thorarensen \u00d3, de Schipper E, Boberg J, Andr\u00e9n P, Tian C; PGC TS-working group; 23andMe Research Team; Als TD, Nissen JB, Meier SM, Bybjerg-Grauholm J, Hougaard DM, Werge T, B\u00f8rglum AD, Hinds DA, R\u00fcck C, Mataix-Cols D, Stef\u00e1nsson H, Stefansson K, Crowley JJ<\/strong>, Mattheisen M.<\/p>\n

Biol Psychiatry. 2024 Oct 8:S0006-3223(24)01648-2. doi: 10.1016\/j.biopsych.2024.07.025. Online ahead of print.<\/p>\n

PMID:\u00a039389409<\/p>\n

 <\/p>\n

Novel Missense Variant in the SMARCD1 Gene as the Cause of Coffin-Siris Syndrome 11 in a Fetus With Ambiguous Genitalia and Multiple Dysmorphic Features.\u00a0<\/a><\/p>\n

Veazey RA, Fisher AJ, Talati AN<\/strong>, Hardisty E, Gilmore KL, Vora NL.<\/strong><\/p>\n

Prenat Diagn. 2024 Oct 10. doi: 10.1002\/pd.6683. Online ahead of print.<\/p>\n

PMID:\u00a039389935\u00a0No abstract available.<\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published 13 papers during September 29th – October 12th, 2024.<\/p>\n","protected":false},"author":41712,"featured_media":6539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[246,49,480,129,57,71,58,100,122,361,448,244,34,243,171,36,355,76,317,30,84,33,428,566,162,28,577,321,483,170],"class_list":["post-14457","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-aygun","tag-berg","tag-bond","tag-broadaway","tag-crowley","tag-foreman","tag-halvorsen","tag-heise","tag-kim","tag-le","tag-li-x","tag-liang","tag-love","tag-matoba","tag-milko","tag-mohlke","tag-mory","tag-powell","tag-powell-cm","tag-publications","tag-raffield","tag-stein","tag-sun-q","tag-talati","tag-tsagaratou","tag-unc-genetics","tag-valone","tag-vora","tag-wolter","tag-zannas","odd"],"acf":[],"yoast_head":"\nDepartment of Genetics Publications for September 29th - 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