{"id":14719,"date":"2025-02-06T16:56:11","date_gmt":"2025-02-06T21:56:11","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=14719"},"modified":"2025-02-06T16:56:11","modified_gmt":"2025-02-06T21:56:11","slug":"department-of-genetics-publications-for-january-19th-february-1st-2025","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-january-19th-february-1st-2025\/","title":{"rendered":"Department of Genetics Publications for January 19th – February 1st, 2025"},"content":{"rendered":"

\"UNCDepartment of Genetics faculty, postdocs, students and collaborators published 17 papers during January 19th – February 1st 2025.<\/p>\n

 <\/p>\n

The X chromosome’s influences on the human brain.\u00a0<\/a><\/p>\n

Jiang Z, Sullivan PF<\/strong>, Li T, Zhao B, Wang X, Luo T, Huang S, Guan PY, Chen J, Yang Y, Stein JL, Li Y<\/strong>, Liu D, Sun L, Zhu H.<\/strong><\/p>\n

Sci Adv. 2025 Jan 24;11(4):eadq5360. doi: 10.1126\/sciadv.adq5360. Epub 2025 Jan 24.<\/p>\n

PMID:\u00a039854466<\/p>\n

 <\/p>\n

Multiplexed single-cell imaging reveals diverging subpopulations with distinct senescence phenotypes during long-term senescence induction.\u00a0<\/a><\/p>\n

Sessions GA, Loops MV, Diekman BO, Purvis JE.<\/strong><\/p>\n

Geroscience. 2025 Jan 23. doi: 10.1007\/s11357-024-01503-7. Online ahead of print.<\/p>\n

PMID:\u00a039849264<\/p>\n

 <\/p>\n

Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders.\u00a0<\/a><\/p>\n

Lee S, McAfee JC, Lee J, Gomez A, Ledford AT, Clarke D, Min H, Gerstein MB, Boyle AP, Sullivan PF, Beltran AS, Won H.<\/strong><\/p>\n

Cell. 2025 Jan 20:S0092-8674(24)01435-1. doi: 10.1016\/j.cell.2024.12.022. Online ahead of print.<\/p>\n

PMID:\u00a039848247<\/p>\n

 <\/p>\n

Genomics yields biological and phenotypic insights into bipolar disorder.\u00a0<\/a><\/p>\n

O’Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, Agerbo E, Albani D, Alemany S, Alliey-Rodriguez N, Als TD, Andlauer TFM, Antoniou A, Ask H, Bass N, Bauer M, Beins EC, Bigdeli TB, Pedersen CB, Boks MP, B\u00f8rte S, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cabana-Dom\u00ednguez J, Cairns MJ, Carpiniello B, Casas M, Cervantes P, Chatzinakos C, Chen HC, Clarence T, Clarke TK, Claus I, Coombes B, Corfield EC, Cruceanu C, Cuellar-Barboza A, Czerski PM, Dafnas K, Dale AM, Dalkner N, Degenhardt F, DePaulo JR, Djurovic S, Drange OK, Escott-Price V, Fanous AH, Fellendorf FT, Ferrier IN, Forty L, Frank J, Frei O, Freimer NB, Fullard JF, Garnham J, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha TH, Hahn T, Haraldsson M, Hautzinger M, Havdahl A, Heilbronner U, Hellgren D, Herms S, Hickie IB, Hoffmann P, Holmans PA, Huang MC, Ikeda M, Jamain S, Johnson JS, Jonsson L, Kalman JL, Kamatani Y, Kennedy JL, Kim E, Kim J, Kittel-Schneider S, Knowles JA, Kogevinas M, Kranz TM, Krebs K, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Maier W, Maihofer AX, Malaspina D, Manchia M, Maratou E, Martinsson L, Mattheisen M, McGregor NW, McInnis MG, McKay JD, Medeiros H, Meyer-Lindenberg A, Millischer V, Morris DW, Moutsatsou P, M\u00fchleisen TW, O’Donovan C, Olsen CM, Panagiotaropoulou G, Papiol S, Pardi\u00f1as AF, Park HY, Perry A, Pfennig A, Pisanu C, Potash JB, Quested D, Rapaport MH, Regeer EJ, Rice JP, Rivera M, Schulte EC, Senner F, Shadrin A, Shilling PD, Sigurdsson E, Sindermann L, Sirignano L, Siskind D, Slaney C, Sloofman LG, Smeland OB, Smith DJ, Sobell JL, Soler Artigas M, Stein DJ, Stein F, Su MH, Sung H, \u015awi\u0105tkowska B, Terao C, Tesfaye M, Tesli M, Thorgeirsson TE, Thorp JG, Toma C, Tondo L, Tooney PA, Tsai SJ, Tsermpini EE, Vawter MP, Vedder H, Vreeker A, Walters JTR, Winsvold BS, Witt SH, Won HH, Ye R, Young AH, Zandi PP, Zillich L; 23andMe Research Team; Adolfsson R, Alda M, Alfredsson L, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Biernacka JM, Boehnke M, B\u00f8rglum AD, Breen G, Carr VJ, Catts S, Cichon S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens FA, Hjerling-Leffler J, Hougaard DM, Hveem K, Iwata N, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kircher T, Kirov G, Kuo PH, Land\u00e9n M, Leboyer M, Li QS, Lissowska J, Lochner C, Loughland C, Luykx JJ, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Medland SE, Melle I, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, M\u00fcller-Myhsok B, Myers RM, Myung W, Neale BM, Nievergelt CM, Nordentoft M, N\u00f6then MM, Nurnberger JI, O’Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato CN, Pato MT, Patrinos GP, Pawlak JM, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribas\u00e9s M, Rietschel M, Ripke S, Rouleau GA, Roussos P, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Smoller JW, Squassina A, Stahl EA, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF,<\/strong> Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert CS, Weickert TW, Werge T, Whiteman DC, Zwart JA, Edenberg HJ, McQuillin A, Forstner AJ, Mullins N, Di Florio A, Ophoff RA, Andreassen OA; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium.<\/p>\n

Nature. 2025 Jan 22. doi: 10.1038\/s41586-024-08468-9. Online ahead of print.<\/p>\n

PMID:\u00a039843750<\/p>\n

 <\/p>\n

Circulating proteomic profiles are associated with type 2 diabetes in Asian populations – a longitudinal study.\u00a0<\/a><\/p>\n

Liang Y, Lim CGY, Ritchie SC, Bertin N, Chai JF, Yao J, Li Y<\/strong>, Tai ES, van Dam RM, Sim X.<\/p>\n

J Clin Endocrinol Metab. 2025 Jan 22:dgaf045. doi: 10.1210\/clinem\/dgaf045. Online ahead of print.<\/p>\n

PMID:\u00a039842943<\/p>\n

 <\/p>\n

Additive Value of Polygenic Risk Score to Family History for Type 2 Diabetes Prediction: Results From the All of Us Research Database.\u00a0<\/a><\/p>\n

Drzymalla E, Raffield L<\/strong>, Kolor K, Koyama A, Moonesinghe R, Pavkov ME, Spracklen CN, Khoury MJ.<\/p>\n

Diabetes Care. 2025 Feb 1;48(2):212-219. doi: 10.2337\/dc24-1537.<\/p>\n

PMID:\u00a039841967<\/p>\n

 <\/p>\n

Deep Learning-Enabled Integration of Histology and Transcriptomics for Tissue Spatial Profile Analysis.\u00a0<\/a><\/p>\n

Ge Y, Leng J, Tang Z, Wang K, U K, Zhang SM, Han S, Zhang Y<\/strong>, Xiang J, Yang S, Liu X, Song Y, Wang X, Li Y, Zhao J.<\/p>\n

Research (Wash D C). 2025 Jan 17;8:0568. doi: 10.34133\/research.0568. eCollection 2025.<\/p>\n

PMID:\u00a039830364\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models.\u00a0<\/a><\/p>\n

Milligan C, Cowley DO<\/strong>, Stewart W, Curry AM, Forbes E, Rector B, Hastie A, Liu L, Hawkins GA.<\/p>\n

Brain Sci. 2025 Jan 17;15(1):84. doi: 10.3390\/brainsci15010084.<\/p>\n

PMID:\u00a039851451<\/p>\n

 <\/p>\n

Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders.\u00a0<\/a><\/p>\n

Holmberg A, Pol-Fuster J, Kuja-Halkola R, Larsson H, Lichtenstein P, Chang Z, D’Onofrio BM, Brikell I, Sidorchuk A, Isomura K, Crowley JJ<\/strong>, Martinsson L, R\u00fcck C, Mataix-Cols D, Fern\u00e1ndez de la Cruz L.<\/p>\n

BMJ Ment Health. 2025 Jan 19;28(1):e301323. doi: 10.1136\/bmjment-2024-301323.<\/p>\n

PMID:\u00a039832837\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Understanding metastasis mixed-treatment responses through genomic analyses.\u00a0<\/a><\/p>\n

Garcia-Recio S,<\/strong> Zagami P, Felsheim BM, Wheless A, Thomas K, Trimarchi R, Carey LA, Perou CM.<\/strong><\/p>\n

NPJ Breast Cancer. 2025 Jan 30;11(1):9. doi: 10.1038\/s41523-025-00724-z.<\/p>\n

PMID:\u00a039885167<\/p>\n

 <\/p>\n

Variational Autoencoder-based Model Improves Polygenic Prediction in Blood Cell Traits.\u00a0<\/a><\/p>\n

Li X, Pang M, Wen J<\/strong>, Zhou LY, Raffield LM<\/strong>, Zhou H, Yao H, Chen C, Sun Q, Li Y.<\/strong><\/p>\n

bioRxiv [Preprint]. 2025 Jan 18:2025.01.13.632820. doi: 10.1101\/2025.01.13.632820.<\/p>\n

PMID:\u00a039868173\u00a0Free PMC article.<\/strong>\u00a0Preprint.<\/p>\n

 <\/p>\n

Species Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with\u00a0in Vivo<\/em>\u00a0Anti-alphaviral Activity.\u00a0<\/a><\/p>\n

Hossain MA, Mayo AK, Ghoshal A, Taft-Benz SA, Anderson EJ, Morales NL, Pressey KD, Vargason AM, Brouwer KLR, Moorman NJ, Heise MT<\/strong>, Willson TM.<\/p>\n

bioRxiv [Preprint]. 2025 Jan 16:2025.01.13.632788. doi: 10.1101\/2025.01.13.632788.<\/p>\n

PMID:\u00a039868137\u00a0Free PMC article.<\/strong>\u00a0Preprint.<\/p>\n

 <\/p>\n

Epigenetic mechanisms underlying endometrial cancer (EC) outcomes: race-specific patterns of DNA methylation associated with molecular subtypes and survival.\u00a0<\/a><\/p>\n

Hoos E, Koval LE, Corcoran DL<\/strong>, Eaves LA, Roell K, Rager JE, Tan X, Godfrey S, Keku TO, Bae-Jump V, Olshan AF, Nichols HB, Weissman BE, Fry RC.<\/p>\n

Carcinogenesis. 2025 Jan 28:bgaf004. doi: 10.1093\/carcin\/bgaf004. Online ahead of print.<\/p>\n

PMID:\u00a039873457<\/p>\n

 <\/p>\n

Obsessive-compulsive symptoms in individuals with a history of eating disorders.\u00a0<\/a><\/p>\n

Kapadia A, Thornton LM, Munn-Chernoff MA, Abramovitch A, McKay D, Abramowitz JS, Yilmaz Z, Crowley JJ<\/strong>, Bulik CM, Watson HJ.<\/p>\n

J Affect Disord. 2025 Jan 24:S0165-0327(25)00085-0. doi: 10.1016\/j.jad.2025.01.068. Online ahead of print.<\/p>\n

PMID:\u00a039864784<\/p>\n

 <\/p>\n

Prenatal gene editing for neurodevelopmental diseases: Ethical considerations.\u00a0<\/a><\/p>\n

Major RM, Juengst ET.<\/strong><\/p>\n

Am J Hum Genet. 2025 Jan 22:S0002-9297(25)00003-5. doi: 10.1016\/j.ajhg.2025.01.003. Online ahead of print.<\/p>\n

PMID:\u00a039879986\u00a0Review.<\/p>\n

 <\/p>\n

Circulating small RNAs shed new light on dementia risk.\u00a0<\/a><\/p>\n

Zannas AS.<\/strong><\/p>\n

Alzheimers Dement. 2025 Jan 27:e14546. doi: 10.1002\/alz.14546. Online ahead of print.<\/p>\n

PMID:\u00a039868762\u00a0No abstract available.<\/p>\n

 <\/p>\n

Pay-it-forward strategy reduced HPV vaccine delay and increased uptake among catch-up age girls: A randomized clinical trial.\u00a0<\/a><\/p>\n

Li J, Li Y, Qi C, He Y, Lu H, Xie Y, Ong JJ, Lu Y, Yang Y, Yang F, Du H, Gong W, Zou F<\/strong>, Larson HJ, Jit M, Lin L, Smith JS, Geng EH, Xu D, Tang W, Tang S, Tucker JD, Wu D.<\/p>\n

medRxiv [Preprint]. 2025 Jan 17:2025.01.16.25320655. doi: 10.1101\/2025.01.16.25320655.<\/p>\n

PMID:\u00a039867381\u00a0Free PMC article.<\/strong>\u00a0Preprint.<\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published 17 papers during January 19th – February 1st 2025.<\/p>\n","protected":false},"author":41712,"featured_media":6539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[287,310,405,260,57,406,100,77,56,451,45,30,27,84,506,33,55,28,373,42,170,435,85],"class_list":["post-14719","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-beltran","tag-chen","tag-corcoran","tag-cowley","tag-crowley","tag-garcia-recio","tag-heise","tag-juengst","tag-li","tag-major","tag-perou","tag-publications","tag-purvis","tag-raffield","tag-sessions","tag-stein","tag-sullivan","tag-unc-genetics","tag-wen","tag-won","tag-zannas","tag-zhu","tag-zou","odd"],"acf":[],"yoast_head":"\nDepartment of Genetics Publications for January 19th - 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