{"id":14945,"date":"2025-04-04T14:45:28","date_gmt":"2025-04-04T18:45:28","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=14945"},"modified":"2025-04-04T14:47:07","modified_gmt":"2025-04-04T18:47:07","slug":"dr-yun-li-and-collaborators-publish-review-in-ajhg","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/dr-yun-li-and-collaborators-publish-review-in-ajhg\/","title":{"rendered":"Dr. Yun Li and Collaborators Publish Review in AJHG"},"content":{"rendered":"
\"Yun
Yun Li, PhD (Professor, Genetics and Biostatistics) and Quan Sun (Biostatistics doctoral candidate)<\/figcaption><\/figure>\n

Yun Li, PhD (Professor, Genetics and Biostatistics) is a co-corresponding author together with Quan Sun (Biostatistics doctoral candidate) on a new review paper<\/a> published in the American Journal of Human Genetics, titled \u201cOpportunities and challenges of local ancestry in genetic association analysis\u201d.<\/p>\n

\"Mohlke
Drs. Andrea Horimoto, Dr. Laura Raffield, and Dr. Karen Mohlke<\/figcaption><\/figure>\n

Additional authors from the Department of Genetics include Drs. Andrea Horimoto, Dr. Laura Raffield, and Dr. Karen Mohlke.\u00a0 The review summarizes methods for\u00a0local ancestry inference and illustrates how local ancestry can be utilized in various analyses, including admixture mapping, association testing, and polygenic risk score construction. In addition, current challenges in research involving local ancestry, both in terms of the inference itself and its role in genetic association studies are discussed. Finally, future study directions and methodology development opportunities to help more effectively incorporate local ancestry in genetic analyses are proposed.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Yun Li, PhD (Professor, Genetics and Biostatistics) is a co-corresponding author together with Quan Sun (Biostatistics doctoral candidate) on a new review paper published in the American Journal of Human Genetics, titled \u201cOpportunities and challenges of local ancestry in genetic association analysis\u201d.<\/p>\n","protected":false},"author":28418,"featured_media":13880,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[589,56,36,84,428],"class_list":["post-14945","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-horimoto","tag-li","tag-mohlke","tag-raffield","tag-sun-q","odd"],"acf":[],"yoast_head":"\nDr. Yun Li and Collaborators Publish Review in AJHG | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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