{"id":15186,"date":"2025-07-01T15:22:41","date_gmt":"2025-07-01T19:22:41","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=15186"},"modified":"2025-07-01T15:22:41","modified_gmt":"2025-07-01T19:22:41","slug":"department-of-genetics-publications-for-june-1st-28th-2025","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-june-1st-28th-2025\/","title":{"rendered":"Department of Genetics Publications for June 1st – 28th, 2025"},"content":{"rendered":"

\"UNCDepartment of Genetics faculty, postdocs, students and collaborators published 25 papers during June 1st – 28th 2025.<\/p>\n

 <\/p>\n

Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease.\u00a0<\/a><\/p>\n

Kurniansyah N, Strausz SJ, Chittoor G, Gupta S, Justice AE, Hrytsenko Y, Keenan BT, Cade BE, Spitzer BW, Wang H, Huffman J, Moll MR, Haring B, Jung SY, Raffield LM<\/strong>, Kaplan R, Rotter JI, Rich SS, Gharib SA, Bartz TM, Liu PY, Chen H, Fornage M, Hou L, Levy D, Morrison AC, Ochs-Balcom HM, Psaty BM, Wilson PWF, Cho K, Pack AI, Ollila HM, Redline S, Gottlieb DJ, Sofer T; FinnGen; Trans-Omics in Precision Medicine Consortium; VA Million Veteran Program.<\/p>\n

EBioMedicine. 2025 Jun 4;117:105790. doi: 10.1016\/j.ebiom.2025.105790. Online ahead of print.<\/p>\n

PMID:\u00a040472801<\/p>\n

 <\/p>\n

A new mouse model for ozone health effects research.\u00a0<\/a><\/p>\n

Smith GJ,<\/strong> Immormino RM, Ferris MT, Lester SA<\/strong>, Moran TP, Harkema JR, Kelada SNP.<\/strong><\/p>\n

Environ Health Perspect. 2025 Jun 5. doi: 10.1289\/EHP15745. Online ahead of print.<\/p>\n

PMID:\u00a040471753<\/p>\n

 <\/p>\n

Age-Based Genomic Screening: Pediatric Providers’ Perspectives on Implementation.\u00a0<\/a><\/p>\n

Waltz M, Foreman AKM,<\/strong> Gibson RA, Schilling S, Milko LV, Phillips R, O’Daniel JM, Giric S, Foss K<\/strong>, Branch EK, DeJong NA, Hernandez ML, Powell BC, Berg JS,<\/strong> Cadigan RJ, Roberts MC.<\/p>\n

Public Health Genomics. 2025;28(1):180-189. doi: 10.1159\/000545839. Epub 2025 Apr 21.<\/p>\n

PMID:\u00a040258355<\/p>\n

 <\/p>\n

SWI\/SNF ATPase silenced HLF potentiates lung metastasis in solid cancers.\u00a0<\/a><\/p>\n

Zhou J, Hepperla A<\/strong>, Simon JM,<\/strong> Kim K, Hu Q, Zhang C, Dong L, Hu L, Zhang C, Liao C, Fang A, Adachi Y, Fu H, Wang T, Liang Q, Zhao F, Liu H, Takeda M, Fang J, Zhong H, Ly P, Wang L, Kapur P, Xu L, Jia L, Malladi S, Brugarolas J, Simon MC, Li B, Zhang Q.<\/p>\n

Nat Commun. 2025 Jun 5;16(1):5226. doi: 10.1038\/s41467-025-60329-9.<\/p>\n

PMID:\u00a040473600<\/p>\n

 <\/p>\n

Polygenic scores and symptom severity change after internet-delivered cognitive behaviour therapy for depression and anxiety.\u00a0<\/a><\/p>\n

B\u00e4ckman J, Wallert J, Halvorsen M, Crowley JJ<\/strong>, Mataix-Cols D, R\u00fcck C.<\/p>\n

Discov Ment Health. 2025 Jun 2;5(1):82. doi: 10.1007\/s44192-025-00213-6.<\/p>\n

PMID:\u00a040455129\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Risk factors, impact, and healthcare use related to initial suicide attempts: comprehensive analysis of Swedish population.\u00a0<\/a><\/p>\n

Hu K, Nguyen TD, Borges K, Kuja-Halkola R, Butwicka A, Brikell I, Crowley JJ<\/strong>, Chang Z, D’Onofrio BM, Larsson H, Lichtenstein P, R\u00fcck C, Bulik C, Sullivan P<\/strong>, Fang F, Lu Y.<\/p>\n

BMJ Med. 2025 Jun 4;4(1):e001129. doi: 10.1136\/bmjmed-2024-001129. eCollection 2025.<\/p>\n

PMID:\u00a040510927\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Transgenerational diabetogenic effects of preconception exposure to inorganic arsenic in C57BL\/6 mice are associated with dysregulation of DNA methylation and gene expression in G1 and G2 offspring.\u00a0<\/a><\/p>\n

Shang B, Liu T, Hartwell H, Douillet C, Venkatratnam A, Qing S, Miller M, Zou F<\/strong>, Krupenko SA, Ideraabdullah FY, de Villena FP<\/strong>, Fry RC, St\u00fdblo M.<\/p>\n

Arch Toxicol. 2025 Jun 12. doi: 10.1007\/s00204-025-04107-y. Online ahead of print.<\/p>\n

PMID:\u00a040504410<\/p>\n

 <\/p>\n

Extensive differential gene expression and regulation by sex in human skeletal muscle.\u00a0<\/a><\/p>\n

Hanks SC, Mauger AS, Varshney A, Ciotlos DL, Manickam N, Narisu N, Shumway AJ, Orchard P, Erdos MR, Sweeney MD, Okamoto J, Jackson AU, Stringham HM, Bonnycastle LL, Zhou X, Lakka TA, Mohlke KL<\/strong>, Tuomilehto J, Laakso M, Boehnke M, Sethupathy P, Collins FS, Koistinen HA, Parker SCJ, Scott LJ.<\/p>\n

Cell Genom. 2025 May 29:100915. doi: 10.1016\/j.xgen.2025.100915. Online ahead of print.<\/p>\n

PMID:\u00a040480217<\/p>\n

 <\/p>\n

Epigenetic mechanisms underlying variation of IL-6, a well-established inflammation biomarker and risk factor for cardiovascular disease.\u00a0<\/a><\/p>\n

Lundin JI, Peters U, Hu Y, Ammous F, Benjamin EJ, Bis JC, Brody JA, Cushman M, Fuller H, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lappalainen T, Levy D, Liu C, Liu Y, Loos RJF, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Ye T, Zhao W, Raffield LM<\/strong>, Kooperberg C; PAGE Study.<\/p>\n

Atherosclerosis. 2025 May 20;407:120219. doi: 10.1016\/j.atherosclerosis.2025.120219. Online ahead of print.<\/p>\n

PMID:\u00a040480020<\/p>\n

 <\/p>\n

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD.\u00a0<\/a><\/p>\n

Zaiken MC, Jin S, McDonald-Hyman CS, Hartigan CR, Sage PT, Hippen KL, Koehn BH, Panoskaltsis-Mortari A, Riddle MJ, Eide CR, Tolar J, Hill GR, Luznik L, Cutler CS, Ritz JR, Kean LS, Tsagaratou A<\/strong>, Rao A, Blazar BR.<\/p>\n

Blood. 2025 Jun 12;145(24):2813-2827. doi: 10.1182\/blood.2024025036.<\/p>\n

PMID:\u00a039899881<\/p>\n

 <\/p>\n

Genomic Analysis of Trichotillomania.\u00a0<\/a><\/p>\n

Halvorsen MW<\/strong>, Garrett ME, Cuccaro ML, Ashley-Koch AE, Crowley JJ.<\/strong><\/p>\n

Am J Med Genet B Neuropsychiatr Genet. 2025 Jun 13:e33035. doi: 10.1002\/ajmg.b.33035. Online ahead of print.<\/p>\n

PMID:\u00a040511557<\/p>\n

 <\/p>\n

Genome-wide maps of UV damage repair and mutation suppression by CPD photolyase.\u00a0<\/a><\/p>\n

Bohm KA, Laughery MF, Mieczkowski PA<\/strong>, Roberts SA, Curation JJWD.<\/p>\n

Nucleic Acids Res. 2025 Jun 6;53(11):gkaf495. doi: 10.1093\/nar\/gkaf495.<\/p>\n

PMID:\u00a040498072\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Epigenetic aging mediates the association between life course socioeconomic status and decrements in kidney function across a decade.\u00a0<\/a><\/p>\n

Surachman A, Harhay MN, DiMaria-Ghalili RA, Zannas AS<\/strong>, Almeida DM, Coe CL.<\/p>\n

Geroscience. 2025 Jun 12. doi: 10.1007\/s11357-025-01728-0. Online ahead of print.<\/p>\n

PMID:\u00a040500519<\/p>\n

 <\/p>\n

Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators.\u00a0<\/a><\/p>\n

Bryan AF, Justice M, Stutzman AV<\/strong>, McKay DJ<\/strong>, Dowen JM.<\/p>\n

Epigenetics Chromatin. 2025 Jun 9;18(1):33. doi: 10.1186\/s13072-025-00598-2.<\/p>\n

PMID:\u00a040490791\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Old vs. new local ancestry inference in HCHS\/SOL: a comparative study.\u00a0<\/a><\/p>\n

Chen X, Wang H, Broce I, Dale A, Yu B, Zhou LY, Li X<\/strong>, Argos M, Daviglus ML, Cai J,<\/strong> Franceschini N<\/strong>, Sofer T.<\/p>\n

Hum Mol Genet. 2025 Jun 9:ddaf093. doi: 10.1093\/hmg\/ddaf093. Online ahead of print.<\/p>\n

PMID:\u00a040485222<\/p>\n

 <\/p>\n

The impact of early-life exposures on growth and adult gut microbiome composition is dependent on genetic strain and parent- of- origin.\u00a0<\/a><\/p>\n

Huda MN, Kelly E, Barron K, Xue J, Valdar W, Tarantino LM, Schoenrock S, Ideraabdullah FY<\/strong>, Bennett BJ.<\/p>\n

Microbiome. 2025 Jun 16;13(1):143. doi: 10.1186\/s40168-025-02130-w.<\/p>\n

PMID:\u00a040524209\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

A data model for population descriptors in genomic research.\u00a0<\/a><\/p>\n

Khan AT, Adebamowo C, Fullerton SM, Hirbo J, Konigsberg IR, Kraft P, Martin I, Nelson SC, Ramsay M, Wojcik GL, Adebamowo SN, Conomos MP, Darst BF, Hysong MR<\/strong>, Li Y<\/strong>, Martin AR, Mathias RA, Rich SS, Sakoda LC, Schrider DR<\/strong>, Sharma J, Smith JL, Sun Q<\/strong>, Zhang Y; Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium; Gogarten SM.<\/p>\n

Am J Hum Genet. 2025 Jun 9:S0002-9297(25)00192-2. doi: 10.1016\/j.ajhg.2025.05.011. Online ahead of print.<\/p>\n

PMID:\u00a040513563\u00a0Review.<\/p>\n

 <\/p>\n

Benchmarking empirical severity for the Yale-Brown Obsessive Compulsive Scale-Second Edition.\u00a0<\/a><\/p>\n

Pinciotti CM, Avery J, Zhang C, Mu\u00f1oz JS, Berrones D, Cruz VZ, Wiese AD, Anderberg JL, Frederick RM, Mi\u00f1o T, Lanzagorta N, Restrepo Castro JC, Ochoa-Panaifo ME, Goodman WK, Crowley JJ<\/strong>, Storch EA, Cervin M; Latin American Trans-ancestry INitiative for OCD genomics (LATINO); Brazilian Obsessive-Compulsive Spectrum Work Group (GTTOC).<\/p>\n

J Affect Disord. 2025 Jun 18:119719. doi: 10.1016\/j.jad.2025.119719. Online ahead of print.<\/p>\n

PMID:\u00a040541829<\/p>\n

 <\/p>\n

Predictors of Anorexia Nervosa and Obsessive-Compulsive Disorder Comorbidity and Order of Diagnosis in a Danish National Cohort.\u00a0<\/a><\/p>\n

Zhu LY, Larsen JT, Nissen JB, Crowley JJ<\/strong>, Mattheisen M, Bulik CM, Petersen LV, Yilmaz Z.<\/p>\n

Int J Eat Disord. 2025 Jun 17. doi: 10.1002\/eat.24486. Online ahead of print.<\/p>\n

PMID:\u00a040525476<\/p>\n

 <\/p>\n

Early life adversity increases risk for chronic post-traumatic pain, data from humans and rodents.\u00a0<\/a><\/p>\n

McKibben LA, Woolard A<\/strong>, McLean SA, Zhao Y, Verma T, Mickelson J, Lu H, Lobo J, House SL, Beaudoin FL, An X, Stevens JS, Neylan TC, Jovanovic T, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Hendry PL, Sheikh S, Jones CW, Punches BE, Hudak LA, Pascual JL, Seamon MJ, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O’Neil BJ, Sanchez LD, Bruce SE, Sheridan JF, Kessler RC, Koenen KC, Ressler KJ, Linnstaedt SD.<\/p>\n

Pain. 2025 Jun 18. doi: 10.1097\/j.pain.0000000000003555. Online ahead of print.<\/p>\n

PMID:\u00a040539444<\/p>\n

 <\/p>\n

BCAA catabolism targeted therapy for heart failure with preserved ejection fraction.\u00a0<\/a><\/p>\n

Wang M, Liu Z, Ren S, Zhu J, Morisawa N, Chua GL, Zhang X, Wong YK, Su L, Wong MX, Yang J, Jens MT, Li Z, Sun H, Wang Y, Rau CD<\/strong>, Shah SJ, Gao C, Liu Y.<\/p>\n

Theranostics. 2025 May 24;15(13):6257-6273. doi: 10.7150\/thno.105894. eCollection 2025.<\/p>\n

PMID:\u00a040521197\u00a0Free PMC article.<\/strong><\/p>\n

 <\/p>\n

Transparency and ongoing communication with participants in brain organoid research: Consensus of an interdisciplinary working group.\u00a0<\/a><\/p>\n

Cohn B, Doerr M, Feliciano P, Fullerton SM, Hendriks S, Holm S, Hyun I, Jongsma K, Meagher KM, Ross ME, Stein JL<\/strong>, Terry SF, MacDuffie KE.<\/p>\n

Stem Cell Reports. 2025 Jun 19:102546. doi: 10.1016\/j.stemcr.2025.102546. Online ahead of print.<\/p>\n

PMID:\u00a040578353<\/p>\n

 <\/p>\n

Epidemiologic and Bacterial Factors Facilitating Long-Term Transmission of Multidrug-Resistant Tuberculosis in Shanghai, China.\u00a0<\/a><\/p>\n

Lu X, Jiang Y, Zhang R, Zhang Y, Li J, Wang L, Ye Q, Hou R, Lu Y, Zhu X, Ji Y, Gan M<\/strong>, Li M, Liu Q<\/strong>, Shen X, Yang C.<\/p>\n

Clin Infect Dis. 2025 Jun 18:ciaf313. doi: 10.1093\/cid\/ciaf313. Online ahead of print.<\/p>\n

PMID:\u00a040576551<\/p>\n

 <\/p>\n

ACMG SF v3.3 list for reporting of secondary findings in clinical exome and genome sequencing: A policy statement of the American College of Medical Genetics and Genomics (ACMG).\u00a0<\/a><\/p>\n

Lee K<\/strong>, Abul-Husn NS, Amendola LM, Brothers KB, Chung WK, Gollob MH, Gordon AS, Harrison SM, Hershberger RE, Li M, Ondrasik D, Richards CS, Stergachis A, Stewart DR, Martin CL, Miller DT; ACMG Secondary Findings Working Group. Electronic address:\u00a0documents@acmg.net<\/a>.<\/p>\n

Genet Med. 2025 Jun 23;27(8):101454. doi: 10.1016\/j.gim.2025.101454. Online ahead of print.<\/p>\n

PMID:\u00a040568962\u00a0No abstract available.<\/p>\n

 <\/p>\n

3Mont: A multi-omics integrative tool for breast cancer subtype stratification.\u00a0<\/a><\/p>\n

Unlu Yazici M, Marron JS, Bakir-Gungor B, Zou F<\/strong>, Yousef M.<\/p>\n

PLoS One. 2025 Jun 27;20(6):e0326154. doi: 10.1371\/journal.pone.0326154. eCollection 2025.<\/p>\n

PMID:\u00a040577268<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published 25 papers during June 1st – 28th 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