{"id":16324,"date":"2025-11-05T10:42:46","date_gmt":"2025-11-05T15:42:46","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=16324"},"modified":"2025-11-05T10:42:46","modified_gmt":"2025-11-05T15:42:46","slug":"department-of-genetics-publications-for-october-2025","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-october-2025\/","title":{"rendered":"Department of Genetics Publications for October 2025"},"content":{"rendered":"

\"UNCDepartment of Genetics faculty, postdocs, students and collaborators published 40 papers during September 28th – October 31st 2025.<\/p>\n

\n

Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.\u00a0<\/a><\/p>\n

Guo B, Cai Y, Kim D<\/b>, Smit RAJ, Wang Z, Iyer KR, Hilliard AT, Haessler J, Tao R, Broadaway KA<\/b>, Wang Y, Pozdeyev N, St\u00e6ger FF, Yang C, Vanderwerff B, Patki AD, Stalbow L, Lin M, Rafaels N, Shortt J, Wiley L, Stanislawski M, Pattee J, Davis L, Straub PS, Shuey MM, Cox NJ, Lee NR, J\u00f8rgensen ME, Bjerregaard P, Larsen C, Hansen T, Moltke I, Meigs JB, Stram DO, Yin X, Zhou X, Chang KM, Clarke SL, Guarischi-Sousa R, Lankester J, Tsao PS, Buyske S, Graff M, Raffield LM<\/b>, Sun Q, Wilkens LR, Carlson CS, Easton CB, Liu S, Manson JE, Marchand LL, Haiman CA, Mohlke KL<\/b>, Gordon-Larsen P, Albrechtsen A, Boehnke M, Rich SS, Manichaikul A, Rotter JI, Yousri NA, Irvin RM; biobank at the Colorado Center for Personalized Medicine (CCPM); VA Million Veteran Program (MVP); Gignoux C, North KE, Loos RJF, Assimes TL, Peters U, Kooperberg C, Raghavan S, Highland HM, Darst BF.<\/div>\n
Nat Commun. 2025 Oct 1;16(1):8632. doi: 10.1038\/s41467-025-63546-4.<\/div>\n
PMID: 41034193 Free PMC article.<\/div>\n
<\/div>\n
Evolution of\u00a0Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance.\u00a0<\/a><\/div>\n
Culviner PH, Frey AM, Liu Q<\/b>, Ha DTM, Thai PVK, Thu DDA, Quang NL, Calderon R, Lecca L, Caws M, Dunstan SJ, Murray MB, Thuong NTT, Fortune SM.<\/div>\n
Cell. 2025 Sep 30:S0092-8674(25)01036-0. doi: 10.1016\/j.cell.2025.09.005. Online ahead of print.<\/div>\n
PMID: 41033311<\/div>\n
<\/div>\n
Tree-based differential testing using inferential uncertainty for RNA-seq.\u00a0<\/a><\/div>\n
Singh NP, Wu EY, Fan J, Love MI<\/b>, Patro R.<\/div>\n
Genome Res. 2025 Oct 1;35(10):2326-2338. doi: 10.1101\/gr.279981.124.<\/div>\n
PMID: 40841168 Free PMC article.<\/div>\n
<\/div>\n

Real-world use of classic and non-classic psychedelics in Hispanic\/Latino adults with Obsessive-Compulsive Disorder: International findings from the LATINO Study.\u00a0<\/a><\/p>\n

Mathai DS, Robinson JO, Wagner K, Neitzke-Spruill L, Berrones D, Anderberg JL, Frederick RM, Cruz VZ, Mu\u00f1oz JS; Latin American Trans-Ancestry INitiative for OCD genomics; Brazilian Obsessive-Compulsive Spectrum Disorder Working Group; Rodriguez CI, Averill LA, Crowley JJ<\/b>, Storch EA, McGuire AL.<\/div>\n
Braz J Psychiatry. 2025 Sep 29. doi: 10.47626\/1516-4446-2025-4316. Online ahead of print.<\/div>\n
PMID: 41024388<\/div>\n
<\/div>\n
A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics.\u00a0<\/a><\/div>\n
Lu KY, Yang X, Eldridge MJG, Sun R<\/b>, Giorgio RT, Morris BI, Wagner NJ, Hardy B, Axtman M, Rowe SE, Wang X, Fowler VG Jr, Liu Q<\/b>, Helaine S, Pearce KH, Conlon BP.<\/div>\n
Nat Microbiol. 2025 Oct 10. doi: 10.1038\/s41564-025-02124-2. Online ahead of print.<\/div>\n
PMID: 41073665<\/div>\n
<\/div>\n
Admixture Mapping Analysis Reveals Genetic Determinants of the Human Plasma Proteome.\u00a0<\/a><\/div>\n
Cruz DE, Deng S, Tahir UA, Chen ZZ, Benson MD, Tuftin B, Chen J<\/b>, Farrell L, Shen D, Meyer M, Lange E, Gao Y, Hall ME, Tracy RP, Rich SS, Taylor K, Manichaikul A, Rotter JI, Sofer T, Wilson JG, Gerszten RE, Raffield LM<\/b>; National Heart, Lung, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium.<\/div>\n
HGG Adv. 2025 Oct 8:100529. doi: 10.1016\/j.xhgg.2025.100529. Online ahead of print.<\/div>\n
PMID:\u00a041069105<\/div>\n
<\/div>\n
High-throughput cytological profiling uncovers genotype-phenotype associations in <\/a>Mycobacterium tuberculosis<\/a><\/i>\u00a0clinical isolates.\u00a0<\/a><\/div>\n
Liu Q<\/b>, Liu YJ, Liu R, Culviner PH, Wang X, Wolf ID, Chen K<\/b>, Chen Y, Xiao Y, Zhang G, Sun R<\/b>, Wakabayashi S, Howard NC, Gan M<\/b>, Rubin EJ, Fortune SM, Zhu J.<\/div>\n
mSystems. 2025 Oct 9:e0097225. doi: 10.1128\/msystems.00972-25. Online ahead of print.<\/div>\n
PMID: 41065399<\/div>\n
<\/div>\n
Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease.\u00a0<\/a><\/div>\n
Kim D<\/b>, Highland HM, Smit RAJ, Hysong MR<\/b>, Buchanan VL, Young KL, Zhao C, Spracklen CN, Kilpel\u00e4inen TO, Guo B, Darst BF, Cai Y, Wang Z, Lundin J, Berndt SI, Manson JE, Marouli E, Lange L, Lange E, Fornage M, Gignoux CR, Haiman CA, Rich SS, Buyske S, Loos RJF, Kooperberg C, Peters U, Avery CL, Gordon-Larsen P, Graff M, Raffield LM<\/b>, North KE.<\/div>\n
Genome Med. 2025 Oct 6;17(1):113. doi: 10.1186\/s13073-025-01522-9.<\/div>\n
PMID: 41053791 Free PMC article.<\/div>\n
<\/div>\n
Mondo: Integrating Disease Terminology Across Communities.\u00a0<\/a><\/div>\n
Vasilevsky NA, Toro S<\/b>, Matentzoglu N, Flack JE, Mullen KR<\/b>, Hegde H, Gehrke S, Whetzel PL, Shwetar Y<\/b>, Harris NL, Ngu MS, Alyea GL, Kane MS, Roncaglia P, Sid E, Thaxton CL<\/b>, Wood V, Abraham RS, Achatz MI, Ajuyah P, Amberger JS, Babb L, Baker J, Balhoff JP, Berg JS<\/b>, Bhalla A, Bofill-De Ros X, Braun IR, Broeren EC, Byer BK, Byrne AB, Callahan TJ, Carmody LC, Chan LE, Clause AR, Cohen JS, DeLuca M, Deuitch NT, Flowers M, Fraser J, Fujiwara T, Gitau V, Goldstein JL<\/b>, Gration D, Groza T, Gyori BM, Hankey W<\/b>, Hilton JA, Himmelstein DS, Hong SS, Hoyt CT, Huether R, Hurwitz E<\/b>, Jacobsen JOB, Kikuchi A, K\u00f6hler S, Korn DR<\/b>, Lagorce D, Laraway BJ<\/b>, Li JY, Malheiro AJ, McLaughlin J, Meldal BHM, Mohan S, Moxon SAT, Munoz-Torres MC, Nelson TH, Nicholas FW, Ochoa D, Olson D, Oprea TI, Oskotsky TT, Osumi-Sutherland D, Paris K, Parkinson HE, Pendlington ZM, Peng XP, Pizzino A, Plon SE, Powell BC<\/b>, Ratliff JC, Rehm HL, Remennik L, Riggs ER, Roberts S, Robinson PN, Ross JE, Schaper K<\/b>, Schilder BM, Schmidt JL, Sharp EW, Similuk MN, Smedley D, Sneddon TP<\/b>, Sparks R, Stefancsik R, Stupp GS, Sundar S<\/b>, Takatsuki T, Tammen I, Tshering KC, Unni DR, Valasek E, Vanderver A, Wagner AH, Webb RF, Welter D, Yaya-Stupp D, Zankl A, Zhang XA, McMurry JA<\/b>, Chute CG, Hamosh A, Mungall CJ, Haendel MA.<\/b><\/div>\n
Genetics. 2025 Oct 6:iyaf215. doi: 10.1093\/genetics\/iyaf215. Online ahead of print.<\/div>\n
PMID: 41052288<\/div>\n
<\/div>\n
Obstacles, Opportunities, and Ethical Considerations for Genomic Investigations of Individuals Continuously Hospitalized with Treatment-resistant Schizophrenia.\u00a0<\/a><\/div>\n
Josiassen RC, Xavier RM, Dietterich TE, Harner MK, Filmyer DM, Houpt C, Lichtenstein ML, Farrell M, Shaughnessy RA, Lazaro-Munoz G, Berg JS, Sullivan PF.<\/b><\/div>\n
Schizophr Bull Open. 2025 Sep 4;6(1):sgaf019. doi: 10.1093\/schizbullopen\/sgaf019. eCollection 2025 Jan.<\/div>\n
PMID: 41050266 Free PMC article.<\/div>\n
<\/div>\n
F8 Variants and Inhibitor Development in a Multiethnic Cohort of Nonsevere Haemophilia A.\u00a0<\/a><\/div>\n
Lim\u00a0MY,\u00a0Lee K<\/b>, Johnsen JM, Key NS.<\/div>\n
Haemophilia. 2025 Oct 10. doi: 10.1111\/hae.70143. Online ahead of print.<\/div>\n
PMID: 41071185<\/div>\n
<\/div>\n
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health.\u00a0<\/a><\/div>\n
Zhao Y, Lockhart S, Liu J, Li X<\/b>, Cortes A, Hua X, Gardner EJ, Kentistou KA, Ca\u00f1adas-Garre M, Fabian L, Ho K, Timpson N, Lo Y, Davitte J, Savage DB, Buser-Doepner C, Ong KK, Zhang H, Scott R, O’Rahilly S, Perry JRB.<\/div>\n
Nat Genet. 2025 Oct;57(10):2436-2444. doi: 10.1038\/s41588-025-02364-2. Epub 2025 Oct 10.<\/div>\n
PMID: 41073786<\/div>\n
<\/div>\n
Multifocality in sporadic medullary thyroid carcinoma is associated with low tumor grade and no difference in somatic driver mutations or overall survival when compared with unifocal tumors.\u00a0<\/a><\/div>\n
Nigam A, Mederos MA, Aksoy YA, Alzumaili B, Bani MA, Fuchs T, Al Ghuzlan A, Gill AJ, Glover AR, Papachristos A, Repaci A, De Leo A, Tallini G, Ahmadi S, Clausen B, Najdawi F, Barletta J, Shaha AR, Spanheimer P<\/b>, Tuttle RM, Wong RJ, Xu B, Ghossein RA, Ganly I, Untch BR.<\/div>\n
Surgery. 2025 Oct 9:109764. doi: 10.1016\/j.surg.2025.109764. Online ahead of print.<\/div>\n
PMID: 41073156<\/div>\n
<\/div>\n
Deciphering the determinants of recombinant protein expression across the human secretome.\u00a0<\/a><\/div>\n
Masson HO, Di Giusto P, Kuo CC, Malm M, Lundqvist M, Sievertsson \u00c5, Berling A, Tegel H, Hober S, Uhlen M, Grassi L, Robasky K<\/b>, Hsieh CL, Hatton D, Rockberg J, Lewis NE.<\/div>\n
Proc Natl Acad Sci U S A. 2025 Oct 14;122(41):e2506036122. doi: 10.1073\/pnas.2506036122. Epub 2025 Oct 7.<\/div>\n
PMID: 41055974<\/div>\n
<\/div>\n
Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.\u00a0<\/a><\/div>\n
Weinstock JS, Chaudhry SA, Ioannou M, Viskadourou M, Reventun P, Jakubek YA, Liggett LA, Laurie C, Broome JG, Khan A, Taylor KD, Guo X, Peyser PA, Boerwinkle E, Chami N, Kenny EE, Loos RJ, Psaty BM, Tracy RP, Brody JA, Yun JH, Cho MH, Vasan RS, Kardia SL, Smith JA, Raffield LM,<\/b>\u00a0Bidulescu A, O’Brien EC, de Andrade M, Rotter JI, Rich SS, Tracy RP, Chen YI, Gu CC, Hsiung CA, Kooperberg C, Haring B, Nassir R, Mathias R, Reiner A, Sankaran VG, Lowenstein CJ, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Natarajan P, Jaiswal S, Bick A, Post WS, Scheet P, Auer P, Karantanos T, Battle A, Arvanitis M.<\/div>\n
Nat Commun. 2025 Oct 16;16(1):9194. doi: 10.1038\/s41467-025-64236-x.<\/div>\n
PMID: 41102182 Free PMC article.<\/div>\n
<\/div>\n
Prognostic significance of CD8+ T cell Spatial Biomarkers in ER+ and ER- breast cancer: A retrospective cohort study.\u00a0<\/a><\/div>\n
Walker AE, Gao X, Wang Q, De la Cruz G, Li D, Perou CM<\/b>, Saltz J, Marron JS, Hoadley KA<\/b>, Troester MA.<\/div>\n
PLoS Med. 2025 Oct 15;22(10):e1004647. doi: 10.1371\/journal.pmed.1004647. Online ahead of print.<\/div>\n
PMID: 41091832<\/div>\n
<\/div>\n
N<\/a><\/i><\/b>-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity.\u00a0<\/a><\/div>\n
Ghoshal A, Sears JD, Hossain MA, Tse EG, Howell S, Burdick JE, Morales NL, Martinez SA, Law I<\/b>, Streblow ZJ, Streblow DN, Cou\u00f1ago RM, Moorman NJ, Heise MT<\/b>, Willson TM.<\/div>\n
J Med Chem. 2025 Oct 15. doi: 10.1021\/acs.jmedchem.5c01802. Online ahead of print.<\/div>\n
PMID: 41090377<\/div>\n
<\/div>\n
Optimizing genetic ancestry adjustment in DNA methylation studies: a comparative analysis of approaches.\u00a0<\/a><\/div>\n
H\u00f6ffler KD, Katrinli S, Halvorsen MW<\/b>, Stavrum AK, O’Connell KS, Shadrin A, Djurovic S, Andreassen OA, Crowley JJ<\/b>, Haavik J, Hagen K, Kvale G, Ressler K, Hansen B, Soares JC, Fries GR, Smith AK, Le Hellard S.<\/div>\n
Epigenetics Chromatin. 2025 Oct 14;18(1):69. doi: 10.1186\/s13072-025-00627-0.<\/div>\n
PMID: 41088295 Free PMC article.<\/div>\n
<\/div>\n
Activating NRF2<\/a>E79Q<\/a><\/sup>\u00a0mutation alters the differentiation of human non-small cell lung cancer.\u00a0<\/a><\/div>\n
Hamad SH, Joshi H, Hess T, Jefferys SR, Saleh Z, Bendjilali N, Sellers RS, Zhu G, Shrank T, Moore RT, Corcoran D<\/b>, Simon JM<\/b>, Spitz FR, Shersher D, Major MB, Weissman BE.<\/div>\n
Cancer Gene Ther. 2025 Oct 11. doi: 10.1038\/s41417-025-00966-w. Online ahead of print.<\/div>\n
PMID: 41076449<\/div>\n
<\/div>\n
Structure-guided design and engineering of a biparatopic antibody targeting CCR2 in triple negative breast cancer.\u00a0<\/a><\/div>\n
Little TS, Wang Y, Chaudhari AP, Budayr OM, Tetterton-Kellner JG, Bastian A, Brown AD, Jasiewicz NE, McCue A, Earp HS, Miller BC<\/b>, Nguyen J.<\/div>\n
J Control Release. 2025 Oct 15:114340. doi: 10.1016\/j.jconrel.2025.114340. Online ahead of print.<\/div>\n
PMID: 41106435<\/div>\n
<\/div>\n
Treatment of Single Patient With PMM2-Congenital Disorder of Glycosylation With Govorestat (AT-007), an Aldose Reductase Inhibitor.\u00a0<\/a><\/div>\n
Jalazo ER, Weisenfeld LA, Ligezka A, Perfetti R,\u00a0Muenzer J.<\/b><\/div>\n
JIMD Rep. 2025 Oct 12;66(6):e70043. doi: 10.1002\/jmd2.70043. eCollection 2025 Nov.<\/div>\n
PMID: 41089670 Free PMC article.<\/div>\n
<\/div>\n
A scalable framework for identifying allelic series from summary statistics.\u00a0<\/a><\/div>\n
McCaw ZR, Gao J, Dey R, Tucker S, Zhang Y<\/b>; insitro Research Team; Gronsbell J, Li X<\/b>, Fox E, O’Dushlaine C, Soare TW.<\/div>\n
Am J Hum Genet. 2025 Oct 13:S0002-9297(25)00368-4. doi: 10.1016\/j.ajhg.2025.09.012. Online ahead of print.<\/div>\n
PMID: 41086816<\/div>\n
<\/div>\n
Unmet needs in the treatment and care of somatic manifestations in mucopolysaccharidosis type II: A targeted literature review.\u00a0<\/a><\/div>\n
Burton BK, Fertek D, Chin PS, Ho C, Giugliani R, van den Hout JMP, Magner M, Ezg\u00fc F, AlSayed M, Muenzer J<\/b>, Okuyama T, Jones SA.<\/div>\n
Mol Genet Metab. 2025 Sep 29;146(3):109248. doi: 10.1016\/j.ymgme.2025.109248. Online ahead of print.<\/div>\n
PMID: 41075684<\/div>\n
<\/div>\n
Association of Epigenetic Age Acceleration and Mitochondrial DNA-Based Aging Metrics Provides Insights Into Mechanisms of Aging-Related Diseases.\u00a0<\/a><\/div>\n
Wang M, Zheng Y, Lai M, Saake E, Liu X, Guo X, Taylor KD, Huan T, Joehanes R, Nannini DR, Zhang K, Lake NJ, Castellani CA, Rich SS, Rotter JI, Liu Y, Raffield LM<\/b>, Carson AP, Fornage M, Ma J, Arking DE, Hou L, Levy D, Liu C.<\/div>\n
Aging Cell. 2025 Oct 24:e70279. doi: 10.1111\/acel.70279. Online ahead of print.<\/div>\n
PMID: 41132105<\/div>\n
<\/div>\n
Association between neutrophil to lymphocyte ratio and Alzheimer’s disease in large biobank cohorts.\u00a0<\/a><\/div>\n
Drzymalla E,<\/b>\u00a0Avery C, Palta P, Reiner AP, Sun Q, Raffield LM.<\/b><\/div>\n
J Alzheimers Dis. 2025 Oct 23:13872877251386813. doi: 10.1177\/13872877251386813. Online ahead of print.<\/div>\n
PMID: 41129721<\/div>\n
<\/div>\n
A transcriptional plasticity-aware framework for RNA-seq differential expression analysis.\u00a0<\/a><\/div>\n
Bei C, Wang X, Gan M<\/b>, Takiff HE, Rubin EJ, Zhu J, Gao Q, Liu Q.<\/b><\/div>\n
Brief Bioinform. 2025 Aug 31;26(5):bbaf557. doi: 10.1093\/bib\/bbaf557.<\/div>\n
PMID: 41115211 Free PMC article.<\/div>\n
<\/div>\n
A quantitative, Bayesian-informed approach to gene-specific variant classification: Updated Expert Panel recommendations improve classification of TP53 germline variants for Li-Fraumeni syndrome.\u00a0<\/a><\/div>\n
Fortuno C, Frone MN, Mester J, de la Hoya M, Mai PL, Pesaran T, Achatz MI, Bassett R, Bustamante C, Crowley S, de Andrade KC, Evans DG, Feng B, Fuqua L, Harrell MI, Hatton JN, Huether R, Kesserwan C, Lee K<\/b>, MacFarland SP, Maciaszek JL, Maxwell K, McGoldrick K, Murphy M, Nehoray B, Penkert J, Pinto EM, Plon SE, Schwartz-Levine A, Thompson AS, Wang W, Zambetti GP, Zelley K, James PA, Savage SA, Kratz CP, Spurdle AB.<\/div>\n
Genome Med. 2025 Oct 22;17(1):128. doi: 10.1186\/s13073-025-01536-3.<\/div>\n
PMID: 41126324 Free PMC article. Review.<\/div>\n
<\/div>\n
EssSubgraph improves performance and generalizability of mammalian essential gene prediction with large networks.\u00a0<\/a><\/div>\n
Wen H, Carpenter S, McGinnis K, Nelson A, Smith K<\/b>, Hong T.<\/div>\n
Gigascience. 2025 Oct 24:giaf136. doi: 10.1093\/gigascience\/giaf136. Online ahead of print.<\/div>\n
PMID: 41134033<\/div>\n
<\/div>\n
AI-Driven Variant Annotation for Precision Oncology in Breast Cancer.\u00a0<\/a><\/div>\n
Shukla K, Wang Y, Spanheimer PM<\/b>, Brunk E.<\/div>\n
Clin Transl Sci. 2025 Oct;18(10):e70350. doi: 10.1111\/cts.70350.<\/div>\n
PMID: 41127930 Free PMC article.<\/div>\n
<\/div>\n
Duration of Hospitalization is Associated with the Gut Microbiome in Patients Undergoing Hematopoietic Stem Cell Transplantation: Early Results from a Randomized Trial of Home Versus Hospital Transplantation.\u00a0<\/a><\/div>\n
Andermann TM, Zeng K, Guirales-Medrano S, Groth A, Ramachandran BC, Sun S, Sorgen AA, Hill L, Bush AT, Liu H, Jones C<\/b>, Roach J, Conlon BP, Rao G, Chao NJ, Fodor AA, Sung AD.<\/div>\n
OBM Transplant. 2025;9(3):10.21926\/obm.transplant.2503255. doi: 10.21926\/obm.transplant.2503255. Epub 2025 Aug 25.<\/div>\n
PMID: 41114048 Free PMC article.<\/div>\n
<\/div>\n
Development of self-phenotyping tools to empower patients and improve diagnostics.\u00a0<\/a><\/div>\n
Shefchek K, Ziniel SI, McMurry JA,<\/b>\u00a0Brownstein CA, Brownstein JS, Riggs ER, Might M, Smedley D, Clugston A, Beggs AH, Paterson H, Robinson PN, Vasilevsky NA, Holm IA, Haendel MA.<\/b><\/div>\n
EBioMedicine. 2025 Oct 30;121:105965. doi: 10.1016\/j.ebiom.2025.105965. Online ahead of print.<\/div>\n
PMID: 41172739<\/div>\n
<\/div>\n
Inflammasome targeting for periodontitis prevention is sex dependent.\u00a0<\/a><\/div>\n
Alves T, Swanson KV, Girnary MS, Freire M, Moss K, Divaris K, Beck J, Santos PCP, Brickey WJ, Wrobel JA, Min HY, Syed M, Morelli T, Seaman WT, Preisser JS, Hu D, Preisser H, Makhanova N, Susin C, Vias NP, Styner M, Zhang S, Pirih FQ, Chang J, Gill HS, Lietzan AD, Webster-Cyriaque J,\u00a0Ting JPY<\/b>, Marchesan JT.<\/div>\n
Proc Natl Acad Sci U S A. 2025 Nov 4;122(44):e2507092122. doi: 10.1073\/pnas.2507092122. Epub 2025 Oct 27.<\/div>\n
PMID: 41144672<\/div>\n
<\/div>\n
Genetic mapping in collaborative cross mouse strains identifies loci that affect initial sensitivity to cocaine.\u00a0<\/a><\/div>\n
Schoenrock SA, Gaines CH, Kumar P, Khan S, Farrington J, Ferris MT, de Villena FP, Valdar W<\/b>, Bubier JA, Tarantino LM.<\/b><\/div>\n
Psychopharmacology (Berl). 2025 Oct 27. doi: 10.1007\/s00213-025-06901-z. Online ahead of print.<\/div>\n
PMID: 41143948<\/div>\n
<\/div>\n
Identification and validation of postpartum depression subtypes: a population-based cohort study.\u00a0<\/a><\/div>\n
Bauer AE, Jaholkowski P, Lu Y, Guintivano J, Hannigan LJ, Corfield EC, Tesli M, Andreassen OA, Li Y<\/b>, Reichborn-Kjennerud T, Sullivan PF<\/b>, Meltzer-Brody S, Havdahl A, Ask H.<\/div>\n
EClinicalMedicine. 2025 Oct 9;89:103540. doi: 10.1016\/j.eclinm.2025.103540. eCollection 2025 Nov.<\/div>\n
PMID: 41140460 Free PMC article.<\/div>\n
<\/div>\n
Impact of COVID-19 on Universal Tumor Screening, Referral Rates and Attendance at Cancer Genetic Counseling at a Safety-Net University Hospital.\u00a0<\/a><\/div>\n
Varvoglis DN, Landrum KR, Comer LH, O’Daniel JM<\/b>, Agala CB, Lee LM, Guillem JG.<\/div>\n
Curr Oncol. 2025 Sep 30;32(10):549. doi: 10.3390\/curroncol32100549.<\/div>\n
PMID: 41149469 Free PMC article.<\/div>\n
<\/div>\n
Direct-to-Consumer Genetic Testing.\u00a0<\/a><\/div>\n
O’Daniel JM, Kobelka C, Foss K, Foreman AKM, Milko LV.<\/b><\/div>\n
NEJM Evid. 2025 Nov;4(11):EVIDra2400455. doi: 10.1056\/EVIDra2400455. Epub 2025 Oct 28.<\/div>\n
PMID: 41147825\u00a0Review.<\/div>\n
<\/div>\n
An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy.\u00a0<\/a><\/div>\n
Huffman JE, Gaziano L, Al Sayed ZR, Judy RL, Raffield LM<\/b>, Biddinger KJ, Charest B, Chopra A, Gagnon D, Guo X, Koledova V, Levin MG, Min YI, Pirruccello JP, Reza N, Ruan R, Verma SS, Venkatesh BA, Verma A, Yao J, Carr JJ, Casas JP, Cho K, Lima JAC, Post WS, Rader DJ, Ritchie MD, Shah A, Taylor KD, Terry JG, Rich SS, O’Donnell CJ, Phillips LS, Lunetta KL, Rotter JI, Wilson PWF, Gaziano JM, Damrauer SM; VA Million Veteran Program; Sun YV, Ellinor PT, Joseph J, Aragam KG.<\/div>\n
Nat Genet. 2025 Oct 31. doi: 10.1038\/s41588-025-02372-2. Online ahead of print.<\/div>\n
PMID: 41174181<\/div>\n
<\/div>\n
Impact of renal mass biopsy on decision-making experience for clinical T1 renal masses.\u00a0<\/a><\/div>\n
Gessner KH<\/b>, Deal AM, Feinberg A,\u00a0Myers S, Poulos K, Heiling H, Wobker S, Akella P, Bjurlin MA, Commander C, Milowsky MI, Nielsen ME, Raynor M, Smith AB, Wallen E, Johnson DC, Kim WY<\/b>, Tan HJ.<\/div>\n
J Urol. 2025 Oct 28:101097JU0000000000004832. doi: 10.1097\/JU.0000000000004832. Online ahead of print.<\/div>\n
PMID: 41151063<\/div>\n
<\/div>\n
Chromatin insulators in gene regulation and 3D genome organization.\u00a0<\/a><\/div>\n
Sultana H, Kunar R, Matera AG.<\/b><\/div>\n
Biochem Soc Trans. 2025 Oct 29;53(5):1387-1399. doi: 10.1042\/BST20253036.<\/div>\n
PMID:\u00a041151055 Review.<\/div>\n
<\/div>\n
Simultaneous Omission of Sentinel Lymph Node Biopsy and Radiation in Older Women with Early ER+ Breast Cancer.\u00a0<\/a><\/div>\n
Cox CE, Schumacher J, Lillie M, Carino J, Agrawal Y, Selfridge JM, Gallagher KK, Ollila DW, Casey DL, Greenberg CC, Spanheimer PM.<\/b><\/div>\n
Ann Surg Oncol. 2025 Oct 27. doi: 10.1245\/s10434-025-18631-9. Online ahead of print.<\/div>\n
PMID:\u00a041145934<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published 40 papers in October 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