{"id":16469,"date":"2025-12-11T10:38:23","date_gmt":"2025-12-11T15:38:23","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=16469"},"modified":"2025-12-11T10:39:00","modified_gmt":"2025-12-11T15:39:00","slug":"abdalla-alkhawaja-and-dr-kevin-currin-are-co-first-authors-on-a-newly-published-manuscript-in-the-american-journal-of-human-genetics","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/abdalla-alkhawaja-and-dr-kevin-currin-are-co-first-authors-on-a-newly-published-manuscript-in-the-american-journal-of-human-genetics\/","title":{"rendered":"Abdalla Alkhawaja and Dr. Kevin Currin are co-first authors on a newly published manuscript in the American Journal of Human Genetics"},"content":{"rendered":"<p class=\"lead\"><strong><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-16470 alignright\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/Alkawaja-and-Currin.jpg\" alt=\"Alkawaja and Currin\" width=\"349\" height=\"293\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/Alkawaja-and-Currin.jpg 622w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/Alkawaja-and-Currin-300x252.jpg 300w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/Alkawaja-and-Currin-600x504.jpg 600w\" sizes=\"auto, (max-width: 349px) 100vw, 349px\" \/>Abdalla Alkhawaja<\/strong> (Bioinformatics and Computational Biology Graduate Student in the labs of Karen Mohlke and Terry Furey, UNC Genetics) and <strong>Dr. Kevin Currin<\/strong> are co-first authors on a <a href=\"https:\/\/www.cell.com\/ajhg\/fulltext\/S0002-9297(25)00434-3\">newly published manuscript<\/a> in the <em>American Journal of Human Genetics<\/em> titled \u201cLiver single-nucleus multiome profiling reveals cell-type mechanisms for cardiometabolic traits\u201d.<\/p>\n<p>This publication describes mapping expression and chromatin accessibility QTLs across six liver cell types using single-nucleus multiome technology. The study demonstrates that this approach captures regulatory events often missed in bulk tissue analyses. Integrating these QTLs with relevant GWAS signals improved understanding of the mechanisms connecting genetic variants to cardiometabolic traits.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abdalla Alkhawaja (Bioinformatics and Computational Biology Graduate Student in the labs of Karen Mohlke and Terry Furey, UNC Genetics) and Dr. Kevin Currin are co-first authors on a newly published manuscript in the American Journal of Human Genetics.<\/p>\n","protected":false},"author":28418,"featured_media":16470,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[576,105,109,36],"class_list":["post-16469","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-alkhawaja","tag-currin","tag-furey","tag-mohlke","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO 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