{"id":16475,"date":"2025-12-11T10:53:21","date_gmt":"2025-12-11T15:53:21","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=16475"},"modified":"2025-12-11T10:53:52","modified_gmt":"2025-12-11T15:53:52","slug":"rachel-szymanski-gmb-graduate-student-frank-conlon-lab-has-received-a-prestigious-american-heart-association-fellowship","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/rachel-szymanski-gmb-graduate-student-frank-conlon-lab-has-received-a-prestigious-american-heart-association-fellowship\/","title":{"rendered":"Rachel Szymanski, GMB Graduate Student (Frank Conlon Lab), has received a Prestigious American Heart Association Fellowship"},"content":{"rendered":"<p class=\"lead\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-16476 alignright\" src=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/GMB-headshot.png\" alt=\"Rachel Syzmanski\" width=\"217\" height=\"325\" srcset=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/GMB-headshot.png 692w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/GMB-headshot-200x300.png 200w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/GMB-headshot-684x1024.png 684w, https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2025\/12\/GMB-headshot-600x898.png 600w\" sizes=\"auto, (max-width: 217px) 100vw, 217px\" \/>Rachel Szymanski, a Genetics and Molecular PhD student in the Frank Conlon (Professor of Genetics &amp; Biology) Lab, has received a prestigious American Heart Association fellowship to investigate the role of the CRL4 ubiquitin-ligase complex in embryonic heart development.<\/p>\n<p>Her research shows that CRL4 is essential for early cardiomyocyte proliferation and survival, and its absence leads to embryonic lethality due to heart growth failure. By identifying CRL4\u2019s protein targets, this work may uncover mechanisms of protein stability underlying congenital heart defects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rachel Szymanski, a PhD in the Conlon Lab, has received a prestigious American Heart Association fellowship to investigate the role of the CRL4 ubiquitin-ligase complex in embryonic heart development.<\/p>\n","protected":false},"author":28418,"featured_media":16476,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[87,524],"class_list":["post-16475","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-conlon","tag-szymanski","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rachel Szymanski, GMB 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