{"id":16954,"date":"2026-05-19T13:10:22","date_gmt":"2026-05-19T17:10:22","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=16954"},"modified":"2026-05-19T13:10:22","modified_gmt":"2026-05-19T17:10:22","slug":"science-publishes-genetic-quality-control-policy-article","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/","title":{"rendered":"Science Publishes Genetic Quality Control Policy Article"},"content":{"rendered":"
\"Fernando
Dr. Fernando Pardo-Manuel de Villena (Professor and Chair, UNC Genetics)<\/figcaption><\/figure>\n

A team of scientists from the UNC-CH Department of Genetics and partnering institutions, led by Dr. Fernando Pardo-Manuel de Villena (Professor and Chair, UNC Genetics), published a policy article titled \u201cImprove genetic quality control to increase rigor and reproducibility of mouse research\u201d in the 14 May 2026 issue of Science<\/em><\/a>.<\/p>\n

The paper describes the development of an improved Strain GQC process that incorporates multiple samples per mouse strain, robust estimates of genome replicability, and a dashboard summary that classifies each strain into one of seven types based on clear metrics. \u00a0Adoption of this enhanced GQC process will strengthen the value of animal models in biomedical research.<\/p>\n","protected":false},"excerpt":{"rendered":"

A team of scientists from the UNC-CH Department of Genetics and partnering institutions, led by Dr. Fernando Pardo-Manuel de Villena (Professor and Chair, UNC Genetics), published a policy article titled \u201cImprove genetic quality control to increase rigor and reproducibility of mouse research\u201d in the 14 May 2026 issue of Science. \u00a0<\/p>\n","protected":false},"author":28418,"featured_media":2930,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[38,294,121],"class_list":["post-16954","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-fernando-pardo-manuel-de-villena","tag-fpmdv","tag-pardo-manuel-de-villena","odd"],"acf":[],"yoast_head":"\nScience Publishes Genetic Quality Control Policy Article | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Science Publishes Genetic Quality Control Policy Article | Department of Genetics\" \/>\n<meta property=\"og:description\" content=\"A team of scientists from the UNC-CH Department of Genetics and partnering institutions, led by Dr. Fernando Pardo-Manuel de Villena (Professor and Chair, UNC Genetics), published a policy article titled \u201cImprove genetic quality control to increase rigor and reproducibility of mouse research\u201d in the 14 May 2026 issue of Science. \u00a0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Genetics\" \/>\n<meta property=\"article:published_time\" content=\"2026-05-19T17:10:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"188\" \/>\n\t<meta property=\"og:image:height\" content=\"250\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jonathon Cornett\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jonathon Cornett\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\"},\"author\":{\"name\":\"Jonathon Cornett\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/person\/0291e0ce388bbf007b03c591fc542716\"},\"headline\":\"Science Publishes Genetic Quality Control Policy Article\",\"datePublished\":\"2026-05-19T17:10:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\"},\"wordCount\":128,\"publisher\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg\",\"keywords\":[\"Fernando Pardo Manuel de Villena\",\"FPMDV\",\"Pardo-Manuel de Villena\"],\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\",\"url\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\",\"name\":\"Science Publishes Genetic Quality Control Policy Article | Department of Genetics\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg\",\"datePublished\":\"2026-05-19T17:10:22+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage\",\"url\":\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg\",\"width\":188,\"height\":250,\"caption\":\"Fernando Pardo Manuel de Villena\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/genetics\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Science Publishes Genetic Quality Control Policy Article\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/genetics\/\",\"name\":\"UNC Department of Genetics\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/genetics\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#organization\",\"name\":\"UNC Department of Genetics\",\"url\":\"https:\/\/www.med.unc.edu\/genetics\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Genetics_logo_png_h.png\",\"contentUrl\":\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Genetics_logo_png_h.png\",\"width\":982,\"height\":151,\"caption\":\"UNC Department of Genetics\"},\"image\":{\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/person\/0291e0ce388bbf007b03c591fc542716\",\"name\":\"Jonathon Cornett\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/98e4bc231fa6040a28baebf18731553c0d5371994059fc719ab66b8c323ce609?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/98e4bc231fa6040a28baebf18731553c0d5371994059fc719ab66b8c323ce609?s=96&d=mm&r=g\",\"caption\":\"Jonathon Cornett\"},\"description\":\"Genetics\",\"url\":\"https:\/\/www.med.unc.edu\/genetics\/author\/jcornett\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Science Publishes Genetic Quality Control Policy Article | Department of Genetics","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/","og_locale":"en_US","og_type":"article","og_title":"Science Publishes Genetic Quality Control Policy Article | Department of Genetics","og_description":"A team of scientists from the UNC-CH Department of Genetics and partnering institutions, led by Dr. Fernando Pardo-Manuel de Villena (Professor and Chair, UNC Genetics), published a policy article titled \u201cImprove genetic quality control to increase rigor and reproducibility of mouse research\u201d in the 14 May 2026 issue of Science. \u00a0","og_url":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/","og_site_name":"Department of Genetics","article_published_time":"2026-05-19T17:10:22+00:00","og_image":[{"width":188,"height":250,"url":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","type":"image\/jpeg"}],"author":"Jonathon Cornett","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jonathon Cornett","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#article","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/"},"author":{"name":"Jonathon Cornett","@id":"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/person\/0291e0ce388bbf007b03c591fc542716"},"headline":"Science Publishes Genetic Quality Control Policy Article","datePublished":"2026-05-19T17:10:22+00:00","mainEntityOfPage":{"@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/"},"wordCount":128,"publisher":{"@id":"https:\/\/www.med.unc.edu\/genetics\/#organization"},"image":{"@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","keywords":["Fernando Pardo Manuel de Villena","FPMDV","Pardo-Manuel de Villena"],"articleSection":["News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/","url":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/","name":"Science Publishes Genetic Quality Control Policy Article | Department of Genetics","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/genetics\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage"},"image":{"@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage"},"thumbnailUrl":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","datePublished":"2026-05-19T17:10:22+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#primaryimage","url":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","contentUrl":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","width":188,"height":250,"caption":"Fernando Pardo Manuel de Villena"},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/genetics\/science-publishes-genetic-quality-control-policy-article\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/genetics\/"},{"@type":"ListItem","position":2,"name":"Science Publishes Genetic Quality Control Policy Article"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/genetics\/#website","url":"https:\/\/www.med.unc.edu\/genetics\/","name":"UNC Department of Genetics","description":"","publisher":{"@id":"https:\/\/www.med.unc.edu\/genetics\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/genetics\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.med.unc.edu\/genetics\/#organization","name":"UNC Department of Genetics","url":"https:\/\/www.med.unc.edu\/genetics\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/logo\/image\/","url":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Genetics_logo_png_h.png","contentUrl":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2018\/11\/Genetics_logo_png_h.png","width":982,"height":151,"caption":"UNC Department of Genetics"},"image":{"@id":"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/person\/0291e0ce388bbf007b03c591fc542716","name":"Jonathon Cornett","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.med.unc.edu\/genetics\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/98e4bc231fa6040a28baebf18731553c0d5371994059fc719ab66b8c323ce609?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/98e4bc231fa6040a28baebf18731553c0d5371994059fc719ab66b8c323ce609?s=96&d=mm&r=g","caption":"Jonathon Cornett"},"description":"Genetics","url":"https:\/\/www.med.unc.edu\/genetics\/author\/jcornett\/"}]}},"featured_image":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2017\/10\/fernando-pardo-manuel-de-villena-188x250-150x150.jpg","featured_image_alt":"Fernando Pardo Manuel de Villena","category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/genetics\/category\/news\/"}],"tag_details":[{"name":"Fernando Pardo Manuel de Villena","link":"https:\/\/www.med.unc.edu\/genetics\/tag\/fernando-pardo-manuel-de-villena\/"},{"name":"FPMDV","link":"https:\/\/www.med.unc.edu\/genetics\/tag\/fpmdv\/"},{"name":"Pardo-Manuel de Villena","link":"https:\/\/www.med.unc.edu\/genetics\/tag\/pardo-manuel-de-villena\/"}],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/posts\/16954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/users\/28418"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/comments?post=16954"}],"version-history":[{"count":1,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/posts\/16954\/revisions"}],"predecessor-version":[{"id":16955,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/posts\/16954\/revisions\/16955"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/media\/2930"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/media?parent=16954"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/categories?post=16954"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/genetics\/wp-json\/wp\/v2\/tags?post=16954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}