{"id":2698,"date":"2016-11-07T17:35:00","date_gmt":"2016-11-07T22:35:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/genetics-faculty-publications-for-oct-15-2013-nov-4-2016\/"},"modified":"2020-09-23T12:55:15","modified_gmt":"2020-09-23T16:55:15","slug":"genetics-faculty-publications-for-oct-15-2013-nov-4-2016","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/genetics-faculty-publications-for-oct-15-2013-nov-4-2016\/","title":{"rendered":"Genetics Faculty Publications for Oct 15 \u2013 Nov 4, 2016"},"content":{"rendered":"

<\/p>\n

During the last three weeks, Department of Genetics faculty members, along with their colleagues, have published 21 manuscripts on a wide variety of topics.<\/p>\n

<\/div>\n

A survey of current practices for genomic sequencing test interpretation and reporting processes in US laboratories.<\/a><\/p>\n

O’Daniel JM<\/b>, McLaughlin HM, Amendola LM, Bale SJ, Berg JS<\/b>, Bick D, Bowling KM, Chao EC, Chung WK, Conlin LK, Cooper GM, Das S, Deignan JL, Dorschner MO, Evans JP, Ghazani AA, Goddard KA, Gornick M, Farwell Hagman KD, Hambuch T, Hegde M, Hindorff LA, Holm IA, Jarvik GP, Knight Johnson A, Mighion L, Morra M, Plon SE, Punj S, Richards CS, Santani A, Shirts BH, Spinner NB, Tang S, Weck KE<\/b>, Wolf SM, Yang Y, Rehm HL.
\nGenet Med. 2016 Nov 3. doi: 10.1038\/gim.2016.152. [Epub ahead of print]\nMID: 27811861<\/p>\n

A Mouse Model of Chronic West Nile Virus Disease.<\/a><\/p>\n

Graham JB, Swarts JL, Wilkins C, Thomas S, Green R, Sekine A, Voss KM, Ireton RC, Mooney M, Choonoo G, Miller DR, Treuting PM, Pardo Manuel de Villena F, Ferris MT<\/b>, McWeeney S, Gale M Jr, Lund JM.
\nPLoS Pathog. 2016 Nov 2;12(11):e1005996. doi: 10.1371\/journal.ppat.1005996.
\nPMID: 27806117<\/p>\n

Molecular classification of Crohn’s disease reveals two clinically relevant subtypes.<\/a><\/p>\n

Weiser M, Simon JM, Kochar B, Tovar A, Israel JW, Robinson A, Gipson GR, Schaner MS, Herfarth HH, Sartor RB, McGovern DP, Rahbar R, Sadiq TS, Koruda MJ, Furey TS, Sheikh SZ<\/b>.
\nGut. 2016 Oct 14. pii: gutjnl-2016-312518. doi: 10.1136\/gutjnl-2016-312518. [Epub ahead of print]\nPMID: 27742763<\/p>\n

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population.<\/a><\/p>\n

Ganna A, Genovese G, Howrigan DP, Byrnes A, Kurki MI, Zekavat SM, Whelan CW, Kals M, Nivard MG, Bloemendal A, Bloom JM, Goldstein JI, Poterba T, Seed C, Handsaker RE, Natarajan P, M\u00e4gi R, Gage D, Robinson EB, Metspalu A, Salomaa V, Suvisaari J, Purcell SM, Sklar P, Kathiresan S, Daly MJ, McCarroll SA, Sullivan PF<\/b>, Palotie A, Esko T, Hultman CM, Neale BM.
\nNat Neurosci. 2016 Oct 3. doi: 10.1038\/nn.4404. [Epub ahead of print]\nPMID: 27694993<\/p>\n

A Novel Tobacco Use Phenotype Suggests the 15q25 and 19q13 Loci May be Differentially Associated With Cigarettes per Day and Tobacco-Related Problems.<\/a><\/p>\n

Richmond-Rakerd LS, Otto JM, Slutske WS, Ehlers CL, Wilhelmsen KC<\/b>, Gizer IR.
\nNicotine Tob Res. 2016 Sep 23. pii: ntw260. [Epub ahead of print]\nPMID: 27663783<\/p>\n

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study.<\/a><\/p>\n

Johnson EC, Bjelland DW, Howrigan DP, Abdellaoui A, Breen G, Borglum A, Cichon S, Degenhardt F, Forstner AJ, Frank J, Genovese G, Heilmann-Heimbach S, Herms S, Hoffman P, Maier W, Mattheisen M, Morris D, Mowry B, M\u00fcller-Mhysok B, Neale B, Nenadic I, N\u00f6then MM, O’Dushlaine C, Rietschel M, Ruderfer DM, Rujescu D, Schulze TG, Simonson MA, Stahl E, Strohmaier J, Witt SH; Schizophrenia Working Group of the Psychiatric Genomics Consortium., Sullivan PF<\/b>, Keller MC.
\nPLoS Genet. 2016 Oct 28;12(10):e1006343. doi: 10.1371\/journal.pgen.1006343.
\nPMID: 27792727<\/p>\n

Detecting broad domains and narrow peaks in ChIP-seq data with hiddenDomains.<\/a><\/p>\n

Starmer J, Magnuson T<\/b>.
\nBMC Bioinformatics. 2016 Mar 24;17:144. doi: 10.1186\/s12859-016-0991-z.
\nPMID: 27009150<\/p>\n

Identification of mRNA isoform switching in breast cancer.<\/a><\/p>\n

Zhao W, Hoadley KA, Parker JS, Perou CM<\/b>.
\nBMC Genomics. 2016 Mar 3;17:181. doi: 10.1186\/s12864-016-2521-9.
\nPMID: 26939613<\/p>\n

Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses.<\/a><\/p>\n

Clark SL, McClay JL, Adkins DE, Aberg KA, Kumar G, Nerella S, Xie L, Collins AL, Crowley JJ<\/b>, Quakenbush CR, Hillard CE, Gao G, Shabalin AA, Peterson RE, Copeland WE, Silberg JL, Maes H,Sullivan PF<\/b>, Costello EJ, van den Oord EJ.
\nNicotine Tob Res. 2016 May;18(5):626-31. doi: 10.1093\/ntr\/ntv166.
\nPMID: 26283763<\/p>\n

Widespread Chromatin Accessibility at Repetitive Elements Links Stem Cells with Human Cancer.<\/a><\/p>\n

Gomez NC, Hepperla AJ, Dumitru R, Simon JM<\/b>, Fang F, Davis IJ<\/b>.
\nCell Rep. 2016 Nov 1;17(6):1607-1620. doi: 10.1016\/j.celrep.2016.10.011.
\nPMID: 27806299<\/p>\n

ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.<\/a><\/p>\n

Lang PY, Nanjangud GJ, Sokolsky-Papkov M, Shaw C, Hwang D, Parker JS<\/b>, Kabanov AV, Gershon TR.
\nDevelopment. 2016 Nov 1;143(21):4038-4052.
\nPMID: 27803059<\/p>\n

Draft Genome Sequence of Bacillus luciferensis Isolated from Soil.<\/a><\/p>\n

Townsley L, Caro L, Kelkar H<\/b>, Shank EA.
\nGenome Announc. 2016 Oct 20;4(5). pii: e01140-16. doi: 10.1128\/genomeA.01140-16.
\nPMID: 27795273<\/p>\n

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.<\/a><\/p>\n

Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA<\/b>, Gordenin DA.
\nPLoS Genet. 2016 Oct 27;12(10):e1006385. doi: 10.1371\/journal.pgen.1006385.
\nPMID: 27788131<\/p>\n

Implication of LRRC4C and DPP6 in neurodevelopmental disorders.<\/a><\/p>\n

Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O’Dushlaine C, McCarroll S, Alda M, Jacquemont S, Ordulu Z, Marshall CR, Carter MT, Shaffer LG, Sklar P, Girirajan S, Morton CC, Gusella JF, Turecki G, Stavropoulos DJ, Sullivan PF<\/b>, Scherer SW, Talkowski ME, Ernst C.
\nAm J Med Genet A. 2016 Oct 19. doi: 10.1002\/ajmg.a.38021. [Epub ahead of print]\nPMID: 27759917<\/p>\n

Subtyping sub-Saharan esophageal squamous cell carcinoma by comprehensive molecular analysis.<\/a><\/p>\n

Liu W, Snell JM, Jeck WR, Hoadley KA<\/b>, Wilkerson MD, Parker JS<\/b>, Patel N, Mlombe YB, Mulima G, Liomba NG, Wolf LL, Shores CG, Gopal S, Sharpless NE<\/b>.
\nJCI Insight. 2016 Oct 6;1(16):e88755.
\nPMID: 27734031<\/p>\n

The Mouse Universal Genotyping Array: From Substrains to Subspecies.<\/a><\/p>\n

Morgan AP<\/b>, Fu CP, Kao CY, Welsh CE, Didion JP, Yadgary L, Hyacinth L, Ferris MT, Bell TA, Miller DR,Giusti-Rodriguez P<\/b>, Nonneman RJ, Cook KD, Whitmire JK<\/b>, Gralinski LE, Keller M, Attie AD, Churchill GA, Petkov P, Sullivan PF<\/b>, Brennan JR, McMillan L, Pardo-Manuel de Villena F<\/b>.
\nG3 (Bethesda). 2015 Dec 18;6(2):263-79. doi: 10.1534\/g3.115.022087.
\nPMID: 26684931<\/p>\n

The ‘Omics’ of Voluntary Exercise: Systems Approaches to a Complex Phenotype.<\/a><\/p>\n

Kelly SA, Villena FP, Pomp D<\/b>.
\nTrends Endocrinol Metab. 2015 Dec;26(12):673-5. doi: 10.1016\/j.tem.2015.10.002.
\nPMID: 26555601<\/p>\n

Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study.<\/a><\/p>\n

Li J, Lange LA, Sabourin J, Duan Q, Valdar W,<\/b> Willis MS, Li Y<\/b>, Wilson JG, Lange EM.
\nJ Hum Genet. 2015 Dec;60(12):755-61. doi: 10.1038\/jhg.2015.107.
\nPMID: 26377243<\/p>\n

Chromatin profiling of Drosophila CNS subpopulations identifies active transcriptional enhancers.<\/a><\/p>\n

Pearson JC, McKay DJ<\/b>, Lieb JD, Crews ST.
\nDevelopment. 2016 Oct 15;143(20):3723-3732.
\nPMID: 27802137<\/p>\n

Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells.<\/a><\/p>\n

Guo Y, Flegel K, Kumar J, McKay DJ<\/b>, Buttitta LA.
\nBiol Open. 2016 Oct 13. pii: bio.017525. doi: 10.1242\/bio.017525. [Epub ahead of print]\nPMID: 27737823<\/p>\n

A phase I\/II study of intrathecal idursulfase-IT in children with severe mucopolysaccharidosis II.<\/a><\/p>\n

Muenzer J<\/b>, Hendriksz CJ, Fan Z, Vijayaraghavan S, Perry V, Santra S, Solanki GA, Mascelli MA, Pan L, Wang N, Sciarappa K, Barbier AJ.
\nGenet Med. 2016 Jan;18(1):73-81. doi: 10.1038\/gim.2015.36.
\nPMID: 25834948<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

During the last three weeks, Department of Genetics faculty members, along with their colleagues, have published 21 manuscripts on a wide variety of topics. A survey of current practices for genomic sequencing test interpretation and reporting processes in US laboratories. O’Daniel JM, McLaughlin HM, Amendola LM, Bale SJ, Berg JS, Bick D, Bowling KM, Chao … Read more<\/a><\/p>\n","protected":false},"author":22429,"featured_media":9049,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[49,57,250,109,80,62,271,56,53,59,82,273,68,72,121,63,45,221,272,86,130,54,55,99,148,218,156],"class_list":["post-2698","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-berg","tag-crowley","tag-davis","tag-furey","tag-giusti-rodriguez","tag-hoadley","tag-kelkar","tag-li","tag-magnuson","tag-mckay","tag-mieczkowski","tag-morgan","tag-muenzer","tag-odaniel","tag-pardo-manuel-de-villena","tag-parker","tag-perou","tag-pomp","tag-sharpless","tag-sheikh","tag-simon","tag-starmer","tag-sullivan","tag-valdar","tag-weck","tag-whitmire","tag-wilhelmsen","odd"],"acf":[],"yoast_head":"\nGenetics Faculty Publications for Oct 15 \u2013 Nov 4, 2016 | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/genetics-faculty-publications-for-oct-15-2013-nov-4-2016\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Genetics Faculty Publications for Oct 15 \u2013 Nov 4, 2016 | Department of Genetics\" \/>\n<meta property=\"og:description\" content=\"During the last three weeks, Department of Genetics faculty members, along with their colleagues, have published 21 manuscripts on a wide variety of topics. 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