{"id":2794,"date":"2016-08-02T17:50:00","date_gmt":"2016-08-02T21:50:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/sethupathy-publishes-invited-review-in-current-diabetes-reports\/"},"modified":"2018-02-07T12:16:07","modified_gmt":"2018-02-07T17:16:07","slug":"sethupathy-publishes-invited-review-in-current-diabetes-reports","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/sethupathy-publishes-invited-review-in-current-diabetes-reports\/","title":{"rendered":"Sethupathy publishes invited review in Current Diabetes Reports"},"content":{"rendered":"

<\/p>\n

The article reviews progress in the microRNA field over the past decade, and details findings in pre-clinical studies that have demonstrated that pharmacologic manipulation of microRNAs, mostly in the liver, can modulate metabolic phenotypes and even reverse the course of insulin resistance and diabetes.<\/p>\n

\n
\"Praveen
Praveen Sethupathy, PhD<\/figcaption><\/figure>\n<\/div>\n

Praveen Sethupathy, PhD, Assistant Professor in the Department of Genetics, published an invited review titled \u201cThe Promise and Challenge of Therapeutic MicroRNA Silencing in Diabetes and Metabolic Diseases\u201d in the June issue of Current Diabetes Reports<\/i>. This review addresses progress in the microRNA field over the past decade and details findings in pre-clinical studies that have demonstrated that pharmacologic manipulation of microRNAs, mostly in the liver, can modulate metabolic phenotypes and even reverse the course of insulin resistance and diabetes.<\/p>\n

Sethupathy writes \u201cthere is cautious optimism in the field about microRNA-based therapies for diabetes, several of which are already in various stages of clinical trials.\u201d The review can be found at: http:\/\/link.springer.com\/article\/10.1007%2Fs11892-016-0745-3<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

The article reviews progress in the microRNA field over the past decade, and details findings in pre-clinical studies that have demonstrated that pharmacologic manipulation of microRNAs, mostly in the liver, can modulate metabolic phenotypes and even reverse the course of insulin resistance and diabetes. Praveen Sethupathy, PhD, Assistant Professor in the Department of Genetics, published … Read more<\/a><\/p>\n","protected":false},"author":22429,"featured_media":2795,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-2794","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nSethupathy publishes invited review in Current Diabetes Reports | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/sethupathy-publishes-invited-review-in-current-diabetes-reports\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sethupathy publishes invited review in Current Diabetes Reports | Department of Genetics\" \/>\n<meta property=\"og:description\" content=\"The article reviews progress in the microRNA field over the past decade, and details findings in pre-clinical studies that have demonstrated that pharmacologic manipulation of microRNAs, mostly in the liver, can modulate metabolic phenotypes and even reverse the course of insulin resistance and diabetes. 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