{"id":5343,"date":"2018-03-13T13:26:08","date_gmt":"2018-03-13T17:26:08","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=5343"},"modified":"2018-03-21T13:01:27","modified_gmt":"2018-03-21T17:01:27","slug":"department-of-genetics-publications-for-feb-25-march-10-2018","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-feb-25-march-10-2018\/","title":{"rendered":"Department of Genetics Publications for Feb. 25 – March 10, 2018"},"content":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published eleven papers during Feb. 25 \u2013 March 10, 2018.<\/p>\n

\"UNC<\/p>\n

Identification of seven novel loci associated with amino acid levels using single variant and gene-based tests in 8,545 Finnish men from the METSIM study.<\/a><\/p>\n

Teslovich TM, Kim DS, Yin X, Stanc\u00e1kov\u00e1 A, Jackson AU, Wielscher M, Naj A, Perry JRB, Huyghe JR, Stringham HM,\u00a0Davis JP, Raulerson CK<\/b>, Welch RP, Fuchsberger C, Locke AE, Sim X, Chines PS, Narisu N, Kangas AJ, Soininen P; Genetics of Obesity-related Liver Disease Consortium (GOLD), The Alzheimer’s Disease Genetics Consortium (ADGC), The DIAbetes Genetics Replication And Meta-analysis (DIAGRAM), Ala-Korpela M, Gudnason V, Musani SK, Jarvelin MR, Schellenberg GD, Speliotes EK, Kuusisto J, Collins FS, Boehnke M, Laakso M,\u00a0Mohlke KL<\/b>.<\/p>\n

Hum Mol Genet<\/span>. 2018 Feb 21. doi: 10.1093\/hmg\/ddy067. [Epub ahead of print]\n

PMID: 29481666<\/p>\n

Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer.<\/a><\/p>\n

Siegel MB<\/b>, He X,\u00a0Hoadley KA<\/b>, Hoyle A, Pearce JB, Garrett AL, Kumar S, Moylan VJ, Brady CM, Van Swearingen AE, Marron D, Gupta GP, Thorne LB, Kieran N, Livasy C, Mardis ER,\u00a0Parker JS<\/b>, Chen M, Anders CK, Carey LA,Perou CM<\/b>.<\/p>\n

J Clin Invest<\/span>. 2018 Feb 26. pii: 96153. doi: 10.1172\/JCI96153. [Epub ahead of print]\n

PMID: 29480819<\/p>\n

An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus.<\/a><\/p>\n

Crowther AJ, Lim SA, Asrican B,\u00a0Albright BH<\/b>, Wooten J, Yeh CY, Bao H, Cerri DH, Hu J, Ian Shih YY,\u00a0Asokan A<\/b>, Song J.<\/p>\n

Stem Cell Reports<\/span>. 2018 Feb 17. pii: S2213-6711(18)30044-4. doi: 10.1016\/j.stemcr.2018.01.018. [Epub ahead of print]\n

PMID: 29478897<\/p>\n

The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice.<\/a><\/p>\n

Manvich DF, Webster KA, Foster SL,\u00a0Farrell MS,<\/b>\u00a0Ritchie JC, Porter JH, Weinshenker D.<\/p>\n

Sci Rep<\/span>. 2018 Mar 1;8(1):3840. doi: 10.1038\/s41598-018-22116-z.<\/p>\n

PMID: 29497149<\/p>\n

A randomized approach to speed up the analysis of large-scale read-count data in the application of CNV detection.<\/a><\/p>\n

Wang W, Sun W, Wang W,\u00a0Szatkiewicz J<\/b>.<\/p>\n

BMC Bioinformatics<\/span>. 2018 Mar 1;19(1):74. doi: 10.1186\/s12859-018-2077-6.<\/p>\n

PMID: 29490610<\/p>\n

Observation weights unlock bulk RNA-seq tools for zero inflation and single-cell applications.<\/a><\/p>\n

Van den Berge K, Perraudeau F, Soneson C,\u00a0Love MI<\/b>, Risso D, Vert JP, Robinson MD, Dudoit S, Clement L.<\/p>\n

Genome Biol<\/span>. 2018 Feb 26;19(1):24. doi: 10.1186\/s13059-018-1406-4.<\/p>\n

PMID: 29478411<\/p>\n

Immuno-PET imaging of tumor-infiltrating lymphocytes using zirconium-89 radiolabeled anti-CD3 antibody in immune-competent mice bearing syngeneic tumors.<\/a><\/p>\n

Beckford Vera DR, Smith CC, Bixby LM, Glatt DM, Dunn SS, Saito R,\u00a0Kim WY<\/b>, Serody JS, Vincent BG, Parrott MC.<\/p>\n

PLoS One<\/span>. 2018 Mar 7;13(3):e0193832. doi: 10.1371\/journal.pone.0193832. eCollection 2018.<\/p>\n

PMID: 29513764<\/p>\n

Developmental constraint through negative pleiotropy in the zygomatic arch.<\/a><\/p>\n

Percival CJ, Green R, Roseman CC, Gatti DM, Morgan JL, Murray SA, Donahue LR, Mayeux JM, Pollard KM, Hua K,\u00a0Pomp D<\/b>, Marcucio R, Hallgr\u00edmsson B.<\/p>\n

Evodevo<\/span>. 2018 Jan 27;9:3. doi: 10.1186\/s13227-018-0092-3. eCollection 2018.<\/p>\n

PMID: 29423138<\/p>\n

A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia.<\/a><\/p>\n

Sakamoto K,\u00a0Crowley JJ<\/b>.<\/p>\n

Am J Med Genet B Neuropsychiatr Genet<\/span>. 2018 Mar;177(2):242-256. doi: 10.1002\/ajmg.b.32554. Epub 2017 Jun 14. Review.<\/p>\n

PMID: \u00a029442441<\/p>\n

Ceratocystis cacaofunesta genome analysis reveals a large expansion of extracellular phosphatidylinositol-specific phospholipase-C genes (PI-PLC).<\/a><\/p>\n

Molano EPL, Cabrera OG, Jose J, do Nascimento LC, Carazzolle MF, Teixeira PJPL, Alvarez JC, Tiburcio RA, Tokimatu Filho PM, de Lima GMA, Guido RVC, Corr\u00eaa TLR, Leme AFP,\u00a0<\/span>Mieczkowski P<\/b>, Pereira GAG.<\/p>\n

BMC Genomics<\/span>. 2018 Jan 17;19(1):58. doi: 10.1186\/s12864-018-4440-4.<\/p>\n

PMID: 29343217<\/p>\n

Whole Genome Sequence Analysis of Mutations Accumulated in\u00a0<\/span>rad27<\/i>\u0394<\/b>\u00a0<\/span>Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events.<\/a><\/p>\n

Omer S, Lavi B,\u00a0Mieczkowski PA<\/b>, Covo S, Hazkani-Covo E.<\/p>\n

G3 (Bethesda)<\/span>. 2017 Nov 6;7(11):3775-3787. doi: 10.1534\/g3.117.300262.<\/p>\n

PMID:\u00a0 28974572<\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published eleven papers during Feb. 25 \u2013 March 10, 2018.<\/p>\n","protected":false},"author":22429,"featured_media":2660,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-5343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nDepartment of Genetics Publications for Feb. 25 - March 10, 2018 | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-feb-25-march-10-2018\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" 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