{"id":5948,"date":"2018-04-30T10:41:19","date_gmt":"2018-04-30T14:41:19","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=5948"},"modified":"2018-07-26T13:21:09","modified_gmt":"2018-07-26T17:21:09","slug":"department-of-genetics-publications-for-april-8-21-2018","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-april-8-21-2018\/","title":{"rendered":"Department of Genetics Publications for April 8-21, 2018"},"content":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published thirteen papers during April 8-21, 2018.<\/p>\n

\"UNC<\/p>\n

Meta-Analysis of Airway Epithelia Gene Expression in Asthma.<\/a><\/p>\n

Tsai YH,\u00a0Parker JS<\/b>, Yang IV,\u00a0Kelada SNP<\/b>.<\/p>\n

Eur Respir J. 2018 Apr 12. pii: 1701962. doi: 10.1183\/13993003.01962-2017. [Epub ahead of print]\n

PMID: 29650561<\/p>\n

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights.<\/a><\/p>\n

Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A; Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S, Neale BM, Ophoff RA, O’Donovan MC, Crawford GE, Geschwind DH, Katsanis N,\u00a0Sullivan PF<\/b>, Pasaniuc B, Price AL.<\/p>\n

Nat Genet. 2018 Apr;50(4):538-548. doi: 10.1038\/s41588-018-0092-1. Epub 2018 Apr 9.<\/p>\n

PMID: 29632383<\/p>\n

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.<\/a><\/p>\n

Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, Huo S, Lohman KK, Zhang W, Cook JP, Prins BP, Flannick J, Grarup N, Trubetskoy VV, Kravic J, Kim YJ, Rybin DV, Yaghootkar H, M\u00fcller-Nurasyid M, Meidtner K, Li-Gao R, Varga TV, Marten J, Li J, Smith AV, An P, Ligthart S, Gustafsson S, Malerba G, Demirkan A, Tajes JF, Steinthorsdottir V, Wuttke M, Lecoeur C, Preuss M, Bielak LF, Graff M, Highland HM, Justice AE, Liu DJ, Marouli E, Peloso GM, Warren HR; ExomeBP Consortium; MAGIC Consortium; GIANT Consortium, Afaq S, Afzal S, Ahlqvist E, Almgren P, Amin N, Bang LB, Bertoni AG, Bombieri C, Bork-Jensen J, Brandslund I, Brody JA, Burtt NP, Canouil M, Chen YI, Cho YS, Christensen C, Eastwood SV, Eckardt KU, Fischer K, Gambaro G, Giedraitis V, Grove ML, de Haan HG, Hackinger S, Hai Y, Han S, Tybj\u00e6rg-Hansen A, Hivert MF, Isomaa B, J\u00e4ger S, J\u00f8rgensen ME, J\u00f8rgensen T, K\u00e4r\u00e4j\u00e4m\u00e4ki A, Kim BJ, Kim SS, Koistinen HA, Kovacs P, Kriebel J, Kronenberg F, L\u00e4ll K, Lange LA, Lee JJ, Lehne B, Li H, Lin KH, Linneberg A, Liu CT, Liu J, Loh M, M\u00e4gi R, Mamakou V, McKean-Cowdin R, Nadkarni G, Neville M, Nielsen SF, Ntalla I, Peyser PA, Rathmann W, Rice K, Rich SS, Rode L, Rolandsson O, Sch\u00f6nherr S, Selvin E, Small KS, Stan\u010d\u00e1kov\u00e1 A, Surendran P, Taylor KD, Teslovich TM, Thorand B, Thorleifsson G, Tin A, T\u00f6njes A, Varbo A, Witte DR, Wood AR, Yajnik P, Yao J, Yengo L, Young R, Amouyel P, Boeing H, Boerwinkle E, Bottinger EP, Chowdhury R, Collins FS, Dedoussis G, Dehghan A, Deloukas P, Ferrario MM, Ferri\u00e8res J, Florez JC, Frossard P, Gudnason V, Harris TB, Heckbert SR, Howson JMM, Ingelsson M, Kathiresan S, Kee F, Kuusisto J, Langenberg C, Launer LJ, Lindgren CM, M\u00e4nnist\u00f6 S, Meitinger T, Melander O,\u00a0Mohlke KL<\/b>, Moitry M, Morris AD, Murray AD, de Mutsert R, Orho-Melander M, Owen KR, Perola M, Peters A, Province MA, Rasheed A, Ridker PM, Rivadineira F, Rosendaal FR, Rosengren AH, Salomaa V, Sheu WH, Sladek R, Smith BH, Strauch K, Uitterlinden AG, Varma R, Willer CJ, Bl\u00fcher M, Butterworth AS, Chambers JC, Chasman DI, Danesh J, van Duijn C, Dupuis J, Franco OH, Franks PW, Froguel P, Grallert H, Groop L, Han BG, Hansen T, Hattersley AT, Hayward C, Ingelsson E, Kardia SLR, Karpe F, Kooner JS, K\u00f6ttgen A, Kuulasmaa K, Laakso M, Lin X, Lind L, Liu Y, Loos RJF, Marchini J, Metspalu A, Mook-Kanamori D, Nordestgaard BG, Palmer CNA, Pankow JS, Pedersen O, Psaty BM, Rauramaa R, Sattar N, Schulze MB, Soranzo N, Spector TD, Stefansson K, Stumvoll M, Thorsteinsdottir U, Tuomi T, Tuomilehto J, Wareham NJ, Wilson JG, Zeggini E, Scott RA, Barroso I, Frayling TM, Goodarzi MO, Meigs JB, Boehnke M, Saleheen D, Morris AP, Rotter JI, McCarthy MI.<\/p>\n

Nat Genet. 2018 Apr;50(4):559-571. doi: 10.1038\/s41588-018-0084-1. Epub 2018 Apr 9.<\/p>\n

PMID: 29632382<\/p>\n

A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia.<\/a><\/p>\n

Gon\u00e7alves VF, Cappi C, Hagen CM, Sequeira A, Vawter MP, Derkach A, Zai CC, Hedley PL, Bybjerg-Grauholm J, Pouget JG, Cuperfain AB,\u00a0Sullivan PF<\/b>, Christiansen M, Kennedy JL, Sun L.<\/p>\n

Biol Psychiatry. 2018 May 1;83(9):780-789. doi: 10.1016\/j.biopsych.2018.02.1175. Epub 2018 Mar 15.<\/p>\n

PMID: 29628042<\/p>\n

Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway.<\/a><\/p>\n

Gall B, Pryke K, Abraham J, Mizuno N, Botto S, Sali TM, Broeckel R, Haese N, Nilsen A, Placzek A, Morrison T,\u00a0Heise M<\/b>, Streblow D, DeFilippis V.<\/p>\n

J Virol. 2018 Feb 26;92(6). pii: e01913-17. doi: 10.1128\/JVI.01913-17. Print 2018 Mar 15.<\/p>\n

PMID: 29263267<\/p>\n

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.<\/a><\/p>\n

Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS,\u00a0Mohlke KL<\/b>, Laakso M, Pajukanta P, Ko A.<\/p>\n

Nat Commun. 2018 Apr 17;9(1):1512. doi: 10.1038\/s41467-018-03554-9.<\/p>\n

PMID: 29666371<\/p>\n

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.<\/a><\/p>\n

Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J; 23andMe Research Team, Hagenaars SP, Lewis CM, Ward J, Smith DJ,\u00a0Sullivan PF<\/b>, Haley CS, Breen G, Deary IJ, McIntosh AM.<\/p>\n

Nat Commun. 2018 Apr 16;9(1):1470. doi: 10.1038\/s41467-018-03819-3.<\/p>\n

PMID: 29662059<\/p>\n

Murine Models of Hepatitis A Virus Infection.<\/a><\/p>\n

Hirai-Yuki A,\u00a0Whitmire JK<\/b>, Joyce M, Tyrrell DL, Lemon SM.<\/p>\n

Cold Spring Harb Perspect Med. 2018 Apr 16. pii: a031674. doi: 10.1101\/cshperspect.a031674. [Epub ahead of print]\n

PMID: 29661811<\/p>\n

Gene expression-phenotype associations in adults with eosinophilic esophagitis.<\/a><\/p>\n

Dellon ES,\u00a0Selitsky SR<\/b>, Genta RM, Lash RH,\u00a0Parker JS<\/b>.<\/p>\n

Dig Liver Dis. 2018 Mar 27. pii: S1590-8658(18)30662-5. doi: 10.1016\/j.dld.2018.03.021. [Epub ahead of print]\n

PMID: 29628359<\/p>\n

BK Polyomavirus Genomic Integration and Large T Antigen Expression: Evolving Paradigms in Human Oncogenesis.<\/a><\/p>\n

Kenan DJ,\u00a0Mieczkowski PA<\/b>, Latulippe E, C\u00f4t\u00e9 I, Singh HK, Nickeleit V.<\/p>\n

Am J Transplant. 2017 Jun;17(6):1674-1680. doi: 10.1111\/ajt.14191. Epub 2017 Feb 21.<\/p>\n

PMID: 28039910<\/p>\n

An epigenetic biomarker of aging for lifespan and healthspan.<\/a><\/p>\n

Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD,\u00a0Li Y,<\/b>\u00a0Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S.<\/p>\n

Aging (Albany NY). 2018 Apr 18. doi: 10.18632\/aging.101414. [Epub ahead of print]\n

PMID: 29676998<\/p>\n

Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo.<\/a><\/p>\n

Schaefer KN, Bonello TT, Zhang S, Williams CE, Roberts DM,\u00a0McKay DJ<\/b>, Peifer M.<\/p>\n

PLoS Genet. 2018 Apr 11;14(4):e1007339. doi: 10.1371\/journal.pgen.1007339. [Epub ahead of print]\n

PMID: 29641560<\/p>\n

The Immune Landscape of Cancer.<\/a><\/p>\n

Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A,\u00a0Parker JS<\/b>, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CE;\u00a0Cancer Genome Atlas Research Network<\/b>, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich L.<\/p>\n

Immunity. 2018 Apr 4. pii: S1074-7613(18)30121-3. doi: 10.1016\/j.immuni.2018.03.023. [Epub ahead of print]\n

PMID: 29628290<\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published thirteen papers during April 8-21, 2018.<\/p>\n","protected":false},"author":22429,"featured_media":2660,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-5948","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nDepartment of Genetics Publications for April 8-21, 2018 | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-april-8-21-2018\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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