{"id":7023,"date":"2019-03-27T15:25:55","date_gmt":"2019-03-27T19:25:55","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=7023"},"modified":"2021-06-03T13:45:56","modified_gmt":"2021-06-03T17:45:56","slug":"department-of-genetics-publications-for-march-10-23-2019","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-march-10-23-2019\/","title":{"rendered":"Department of Genetics Publications for March 10-23, 2019"},"content":{"rendered":"

\"\"<\/p>\n

Department of Genetics faculty, postdocs, students and collaborators published fifteen papers during March 10-23, 2019.<\/p>\n\n\n\n\n\n\n
<\/td>\nSingle-Cell Heterogeneity Analysis and CRISPR Screen Identify Key \u03b2-Cell-Specific Disease Genes.<\/a><\/td>\n<\/tr>\n
<\/td>\nFang Z, Weng C, Li H, Tao R, Mai W, Liu X, Lu L, Lai S, Duan Q, Alvarez C, Arvan P, Wynshaw-Boris A, Li Y<\/strong>, Pei Y, Jin F, Li Y.<\/td>\n<\/tr>\n
<\/td>\nCell Rep. 2019 Mar 12;26(11):3132-3144.e7. doi: 10.1016\/j.celrep.2019.02.043.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30865899<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nMapping causal pathways from genetics to neuropsychiatric disorders using genome-wide imaging genetics: current status and future directions.<\/a><\/td>\n<\/tr>\n
<\/td>\nLe BD, Stein JL<\/strong>.<\/td>\n<\/tr>\n
<\/td>\nPsychiatry Clin Neurosci. 2019 Mar 13. doi: 10.1111\/pcn.12839. [Epub ahead of print]<\/td>\n<\/tr>\n
<\/td>\nPMID: 30864184<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nvqtl: An R Package for Mean-Variance QTL Mapping.<\/a><\/td>\n<\/tr>\n
<\/td>\nCorty RW, Valdar W.<\/strong><\/td>\n<\/tr>\n
<\/td>\nG3 (Bethesda). 2018 Dec 10;8(12):3757-3766. doi: 10.1534\/g3.118.200642.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30389795<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nQTL Mapping on a Background of Variance Heterogeneity.<\/a><\/td>\n<\/tr>\n
<\/td>\nCorty RW, Valdar W.<\/strong><\/td>\n<\/tr>\n
<\/td>\nG3 (Bethesda). 2018 Dec 10;8(12):3767-3782. doi: 10.1534\/g3.118.200790.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30389794<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nMean-Variance QTL Mapping Identifies Novel QTL for Circadian Activity and Exploratory Behavior in Mice.<\/a><\/td>\n<\/tr>\n
<\/td>\nCorty RW<\/strong>, Kumar V, Tarantino LM<\/strong>, Takahashi JS, Valdar W<\/strong>.<\/td>\n<\/tr>\n
<\/td>\nG3 (Bethesda). 2018 Dec 10;8(12):3783-3790. doi: 10.1534\/g3.118.200194.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30389793<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nThe three-dimensional landscape of the genome in human brain tissue unveils regulatory mechanisms leading to schizophrenia risk.<\/a><\/td>\n<\/tr>\n
<\/td>\nMah W, Won H.<\/strong><\/td>\n<\/tr>\n
<\/td>\nSchizophr Res. 2019 Mar 17. pii: S0920-9964(19)30089-1. doi: 10.1016\/j.schres.2019.03.007. [Epub ahead of print] Review.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30894290<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nEvidence that the human cell cycle is a series of uncoupled, memoryless phases.<\/a><\/td>\n<\/tr>\n
<\/td>\nChao HX, Fakhreddin RI, Shimerov HK, Kedziora KM<\/strong>, Kumar RJ, Perez J, Limas JC, Grant GD, Cook JG, Gupta GP, Purvis JE.<\/strong><\/td>\n<\/tr>\n
<\/td>\nMol Syst Biol. 2019 Mar 18;15(3):e8604. doi: 10.15252\/msb.20188604.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30886052<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nReciprocal F1 Hybrids of Two Inbred Mouse Strains Reveal Parent-of-Origin and Perinatal Diet Effects on Behavior and Expression.<\/a><\/td>\n<\/tr>\n
<\/td>\nOreper D, Schoenrock SA, McMullan R, Ervin R, Farrington J Miller DR, de Villena FP, Valdar W, Tarantino LM<\/strong>,.<\/td>\n<\/tr>\n
<\/td>\nG3 (Bethesda). 2018 Nov 6;8(11):3447-3468. doi: 10.1534\/g3.118.200135.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30171036<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nHigh-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq.<\/a><\/td>\n<\/tr>\n
<\/td>\nSimon JM<\/strong>, Paranjape SR, Wolter JM, Salazar G, Zylka MJ.<\/td>\n<\/tr>\n
<\/td>\nSci Rep. 2019 Mar 14;9(1):4529. doi: 10.1038\/s41598-019-39016-5.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30872602<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nEndothelial miR-30c suppresses tumor growth via inhibition of TGF-\u03b2-induced Serpine1.<\/a><\/td>\n<\/tr>\n
<\/td>\nMcCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS<\/strong>, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC.<\/td>\n<\/tr>\n
<\/td>\nJ Clin Invest. 2019 Mar 11;130. pii: 123106. doi: 10.1172\/JCI123106. eCollection 2019 Mar 11.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30855280<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nRNA-Sequencing of Umbilical Cord Blood to Investigate Spontaneous Preterm Birth: A Pilot Study.<\/a><\/td>\n<\/tr>\n
<\/td>\nVora NL, Parker JS, Mieckowski PA<\/strong>, Smeester L, Fry RC, Boggess KA.<\/td>\n<\/tr>\n
<\/td>\nAJP Rep. 2019 Jan;9(1):e60-e66. doi: 10.1055\/s-0039-1678717. Epub 2019 Mar 7.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30854245<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nA Case Study of Genomic Instability in an Industrial Strain of <i>Saccharomyces cerevisiae<\/i>.<\/a><\/td>\n<\/tr>\n
<\/td>\nRodrigues-Prause A, Sampaio NMV, Gurol TM, Aguirre GM, Sedam HNC, Chapman MJ, Malc EP<\/strong>, Ajith VP, Chakraborty P<\/strong>, Tizei PA, Pereira GAG, Mieczkowski PA<\/strong>, Nishant KT, Argueso JL.<\/td>\n<\/tr>\n
<\/td>\nG3 (Bethesda). 2018 Nov 6;8(11):3703-3713. doi: 10.1534\/g3.118.200446.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30254181<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nCentrosome Loss Triggers a Transcriptional Program To Counter Apoptosis-Induced Oxidative Stress.<\/a><\/td>\n<\/tr>\n
<\/td>\nPoulton JS, McKay DJ<\/strong>, Peifer M.<\/td>\n<\/tr>\n
<\/td>\nGenetics. 2019 Mar 13. pii: genetics.302051.2019. doi: 10.1534\/genetics.119.302051. [Epub ahead of print]<\/td>\n<\/tr>\n
<\/td>\nPMID: 30867197<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nNext-Generation Sequencing (NGS) Methods Show Superior or Equivalent Performance to Non-NGS Methods on BRAF, EGFR, and KRAS Proficiency Testing Samples.<\/a><\/td>\n<\/tr>\n
<\/td>\nSurrey LF, Oakley FD, Merker JD<\/strong>, Long TA, Vasalos P, Moncur JT, Kim AS.<\/td>\n<\/tr>\n
<\/td>\nArch Pathol Lab Med. 2019 Mar 13. doi: 10.5858\/arpa.2018-0394-CP. [Epub ahead of print]<\/td>\n<\/tr>\n
<\/td>\nPMID: 30865489<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
<\/td>\nLysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation.<\/a><\/td>\n<\/tr>\n
<\/td>\nLeatham-Jensen M, Uyehara CM, Strahl BD, Matera AG, Duronio RJ, McKay DJ.<\/strong><\/td>\n<\/tr>\n
<\/td>\nPLoS Genet. 2019 Jan 30;15(1):e1007932. doi: 10.1371\/journal.pgen.1007932. eCollection 2019 Jan.<\/td>\n<\/tr>\n
<\/td>\nPMID: 30699116<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published fifteen papers during March 10-23, 2019.<\/p>\n","protected":false},"author":28418,"featured_media":6539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[360,103,98,207,364,362,174,294,60,361,56,81,67,59,313,65,82,119,342,121,63,30,27,172,363,130,33,177,28,99,42],"class_list":["post-7023","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-chakraborty","tag-chao","tag-corty","tag-duronio","tag-ervin","tag-fakhreddin","tag-farrington","tag-fpmdv","tag-kedziora","tag-le","tag-li","tag-malc","tag-matera","tag-mckay","tag-mcmullan","tag-merker","tag-mieczkowski","tag-miller","tag-oreper","tag-pardo-manuel-de-villena","tag-parker","tag-publications","tag-purvis","tag-schoenrock","tag-shimerov","tag-simon","tag-stein","tag-tarantino","tag-unc-genetics","tag-valdar","tag-won","odd"],"acf":[],"yoast_head":"\nDepartment of 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