{"id":9627,"date":"2020-11-16T08:30:09","date_gmt":"2020-11-16T13:30:09","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=9627"},"modified":"2020-11-16T08:30:09","modified_gmt":"2020-11-16T13:30:09","slug":"genetics-editors-highlight-paper-by-crouse-kelada-and-valdar-in-december-2020-issue","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/genetics-editors-highlight-paper-by-crouse-kelada-and-valdar-in-december-2020-issue\/","title":{"rendered":"GENETICS Editors Highlight Paper by Crouse, Kelada and Valdar in December 2020 Issue"},"content":{"rendered":"

\"WesDrs. Wesley Crouse, Samir Kelada and Will Valdar (UNC Department of Genetics) published the manuscript \u201cInferring the Allelic Series at QTL in Multiparental Populations\u201d<\/a> in the October 20, 2020 edition of the journal GENETICS.\u00a0 This paper will be featured as an issue highlight in the December 2020 edition of the journal.\u00a0 The article follows:\u00a0 Multiparent populations are experimental populations generated by breeding together a genetically diverse set of inbred\u00a0founder strains to produce individuals whose genomes are random mosaics of the founder haplotypes. In such populations,\u00a0quantitative trait loci are typically detected by associating traits with variation in local haplotype state. This technique is\u00a0powerful for QTL discovery but at present falls short of determining the allelic series, the assignment of haplotypes to\u00a0underlying functional alleles. Crouse, Kelada, and Valdar describe a statistical method\u00a0based on the coalescent\u00a0to infer the\u00a0allelic series, demonstrating its performance by simulation and its use on several real data examples in mice and drosophila.<\/p>\n","protected":false},"excerpt":{"rendered":"

Drs. Wesley Crouse, Samir Kelada and Will Valdar (UNC Department of Genetics) published the manuscript \u201cInferring the Allelic Series at QTL in Multiparental Populations\u201d in the October 20, 2020 edition of the journal GENETICS.\u00a0 This paper will be featured as an issue highlight in the December 2020 edition of the journal.\u00a0 The article follows:\u00a0 Multiparent … Read more<\/a><\/p>\n","protected":false},"author":28418,"featured_media":9628,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[116,50,99],"class_list":["post-9627","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-crouse","tag-kelada","tag-valdar","odd"],"acf":[],"yoast_head":"\nGENETICS Editors Highlight Paper by Crouse, Kelada and Valdar in December 2020 Issue | Department of Genetics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/genetics\/genetics-editors-highlight-paper-by-crouse-kelada-and-valdar-in-december-2020-issue\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GENETICS Editors Highlight Paper by Crouse, Kelada and Valdar in December 2020 Issue | Department of Genetics\" \/>\n<meta property=\"og:description\" content=\"Drs. Wesley Crouse, Samir Kelada and Will Valdar (UNC Department of Genetics) published the manuscript \u201cInferring the Allelic Series at QTL in Multiparental Populations\u201d in the October 20, 2020 edition of the journal GENETICS.\u00a0 This paper will be featured as an issue highlight in the December 2020 edition of the journal.\u00a0 The article follows:\u00a0 Multiparent … Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/genetics\/genetics-editors-highlight-paper-by-crouse-kelada-and-valdar-in-december-2020-issue\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Genetics\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-16T13:30:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.med.unc.edu\/genetics\/wp-content\/uploads\/sites\/481\/2020\/11\/CrouseKeladaValdar2020-e1613507905778.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"576\" \/>\n\t<meta property=\"og:image:height\" content=\"529\" 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