{"id":9957,"date":"2021-02-08T09:30:23","date_gmt":"2021-02-08T14:30:23","guid":{"rendered":"https:\/\/www.med.unc.edu\/genetics\/?p=9957"},"modified":"2021-02-08T09:30:23","modified_gmt":"2021-02-08T14:30:23","slug":"department-of-genetics-publications-for-jan-24-feb-6-2021","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/genetics\/department-of-genetics-publications-for-jan-24-feb-6-2021\/","title":{"rendered":"Department of Genetics Publications for Jan. 24 \u2013 Feb. 6, 2021"},"content":{"rendered":"

\"UNC<\/p>\n

Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 \u2013 Feb. 6, 2021.<\/p>\n

 <\/p>\n

 <\/p>\n

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice.\u00a0<\/a><\/p>\n

Graham JB, Swarts JL, Leist SR, Sch\u00e4fer A, Menachery VD, Gralinski LE, Jeng S, Miller DR<\/strong>, Mooney MA, McWeeney SK, Ferris MT, Pardo-Manuel de Villena F, Heise MT<\/strong>, Baric RS, Lund JM.<\/p>\n

PLoS Pathog. 2021 Jan 29;17(1):e1009287. doi: 10.1371\/journal.ppat.1009287. Online ahead of print.<\/p>\n

PMID:\u00a033513210<\/p>\n

 <\/p>\n

AIM2 in regulatory T cells restrains autoimmune diseases.\u00a0<\/a><\/p>\n

Chou WC<\/strong>, Guo Z, Guo H<\/strong>, Chen L, Zhang G, Liang K, Xie L, Tan X, Gibson SA, Rampanelli E, Wang Y, Montgomery SA, Brickey WJ, Deng M, Freeman L, Zhang S, Su MA, Chen X, Wan YY, Ting JP<\/strong>.<\/p>\n

Nature. 2021 Jan 27. doi: 10.1038\/s41586-021-03231-w. Online ahead of print.<\/p>\n

PMID:\u00a033505023<\/p>\n

 <\/p>\n

Putative modulation of the gut microbiome by probiotics enhances preference for novelty in a preliminary double-blind placebo-controlled study in ferrets.\u00a0<\/a><\/p>\n

Dugyala S, Ptacek TS, Simon JM, Li Y<\/strong>, Fr\u00f6hlich F.<\/p>\n

Anim Microbiome. 2020 May 5;2(1):14. doi: 10.1186\/s42523-020-00030-y.<\/p>\n

PMID:\u00a033499984<\/p>\n

 <\/p>\n

Sox9EGFP<\/sup>\u00a0defines biliary epithelial heterogeneity downstream of Yap activity.\u00a0<\/a><\/p>\n

Tulasi DY, Castaneda DM, Wager K<\/strong>, Hogan CB, Alcedo KP, Raab JR, Gracz AD<\/strong>.<\/p>\n

Cell Mol Gastroenterol Hepatol. 2021 Jan 23:S2352-345X(21)00015-1. doi: 10.1016\/j.jcmgh.2021.01.009. Online ahead of print.<\/p>\n

PMID:\u00a033497866<\/p>\n

 <\/p>\n

FIREcaller: Detecting frequently interacting regions from Hi-C data.\u00a0<\/a><\/p>\n

Crowley C, Yang Y<\/strong>, Qiu Y, Hu B, Abnousi A, Lipi\u0144ski J, Plewczy\u0144ski D, Wu D, Won H<\/strong>, Ren B, Hu M, Li Y<\/strong>.<\/p>\n

Comput Struct Biotechnol J. 2020 Dec 29;19:355-362. doi: 10.1016\/j.csbj.2020.12.026. eCollection 2021.<\/p>\n

PMID:\u00a033489005<\/p>\n

 <\/p>\n

Investigating rare pathogenic\/likely pathogenic exonic variation in bipolar disorder.\u00a0<\/a><\/p>\n

Jia X, Goes FS, Locke AE, Palmer D, Wang W, Cohen-Woods S, Genovese G, Jackson AU, Jiang C, Kvale M, Mullins N, Nguyen H, Pirooznia M, Rivera M, Ruderfer DM, Shen L, Thai K, Zawistowski M, Zhuang Y, Abecasis G, Akil H, Bergen S, Burmeister M, Champion S, DelaBastide M, Jur\u00e9us A, Kang HM, Kwok PY, Li JZ, Levy SE, Monson ET, Moran J, Sobell J, Watson S, Willour V, Z\u00f6llner S, Adolfsson R, Blackwood D, Boehnke M, Breen G, Corvin A, Craddock N, DiFlorio A, Hultman CM, Landen M, Lewis C, McCarroll SA, Richard McCombie W, McGuffin P, McIntosh A, McQuillin A, Morris D, Myers RM, O’Donovan M, Ophoff R, Boks M, Kahn R, Ouwehand W, Owen M, Pato C, Pato M, Posthuma D, Potash JB, Reif A, Sklar P, Smoller J, Sullivan PF<\/strong>, Vincent J, Walters J, Neale B, Purcell S, Risch N, Schaefer C, Stahl EA, Zandi PP, Scott LJ.<\/p>\n

Mol Psychiatry. 2021 Jan 22. doi: 10.1038\/s41380-020-01006-9. Online ahead of print.<\/p>\n

PMID:\u00a033483695<\/p>\n

 <\/p>\n

Genome-wide association study of patients with a severe major depressive episode treated with electroconvulsive therapy.\u00a0<\/a><\/p>\n

Clements CC, Karlsson R, Lu Y, Jur\u00e9us A, R\u00fcck C, Andersson E, Boberg J, Pedersen NL, Bulik CM, Nordenskj\u00f6ld A, P\u00e5lsson E, Sullivan PF<\/strong>, Land\u00e9n M.<\/p>\n

Mol Psychiatry. 2021 Jan 22. doi: 10.1038\/s41380-020-00984-0. Online ahead of print.<\/p>\n

PMID:\u00a033483693<\/p>\n

 <\/p>\n

Sept8\/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model.\u00a0<\/a><\/p>\n

Keele GR<\/strong>, Prokop JW, He H, Holl K, Littrell J, Deal AW, Kim Y, Kyle PB, Attipoe E, Johnson AC, Uhl KL, Sirpilla OL, Jahanbakhsh S, Robinson M, Levy S, Valdar W<\/strong>, Garrett MR, Solberg Woods LC.<\/p>\n

Sci Rep. 2021 Jan 22;11(1):2071. doi: 10.1038\/s41598-021-81550-8.<\/p>\n

PMID:\u00a033483609<\/p>\n

 <\/p>\n

HiC-ACT: improved detection of chromatin interactions from Hi-C data via aggregated Cauchy test.\u00a0<\/a><\/p>\n

Lagler TM, Abnousi A, Hu M, Yang Y, Li Y<\/strong>.<\/p>\n

Am J Hum Genet. 2021 Feb 4;108(2):257-268. doi: 10.1016\/j.ajhg.2021.01.009.<\/p>\n

PMID:\u00a033545029<\/p>\n

 <\/p>\n

Gametes deficient for Pot1 telomere binding proteins alter levels of telomeric foci for multiple generations.\u00a0<\/a><\/p>\n

Lister-Shimauchi EH, Dinh M, <\/strong>Maddox P, Ahmed S.<\/strong><\/p>\n

Commun Biol. 2021 Feb 4;4(1):158. doi: 10.1038\/s42003-020-01624-7.<\/p>\n

PMID:\u00a033542458<\/p>\n

 <\/p>\n

Inferring the structures of signaling motifs from paired dynamic traces of single cells.\u00a0<\/a><\/p>\n

Haggerty RA, Purvis JE.<\/strong><\/p>\n

PLoS Comput Biol. 2021 Feb 4;17(2):e1008657. doi: 10.1371\/journal.pcbi.1008657. Online ahead of print.<\/p>\n

PMID:\u00a033539338<\/p>\n

 <\/p>\n

Whole-genome characterization of lung adenocarcinomas lacking the RTK\/RAS\/RAF pathway.\u00a0<\/a><\/p>\n

Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS<\/strong>, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, Haan D, Yau C, Hinoue T, Liu Y, Shapira O, Kumar K, Mungall KL, Zhang H, Lee JJ, Berger A, Gao GF, Zhitomirsky B, Liang WW, Zhou M, Moorthi S, Berger AH, Collisson EA, Zody MC, Ding L, Cherniack AD, Getz G, Elemento O, Benz CC, Stuart J, Zenklusen JC, Beroukhim R, Chang JC, Campbell JD, Hayes DN, Yang L, Laird PW, Weinstein JN, Kwiatkowski DJ, Tsao MS, Travis WD, Khurana E, Berman BP, Hoadley KA<\/strong>, Robine N; TCGA Research Network, Meyerson M, Govindan R, Imielinski M.<\/p>\n

Cell Rep. 2021 Feb 2;34(5):108707. doi: 10.1016\/j.celrep.2021.108707.<\/p>\n

PMID:\u00a033535033<\/p>\n

 <\/p>\n

TET-Mediated Epigenetic Regulation in Immune Cell Development and Disease.\u00a0<\/a><\/p>\n

Tsiouplis NJ, Bailey DW, Chiou LF, Wissink FJ, Tsagaratou A<\/strong>.<\/p>\n

Front Cell Dev Biol. 2021 Jan 15;8:623948. doi: 10.3389\/fcell.2020.623948. eCollection 2020.<\/p>\n

PMID:\u00a033520997<\/p>\n

 <\/p>\n

Specifications of the variant curation guidelines for ITGA2B\/ITGB3: ClinGen Platelet Disorder Variant Curation Panel.\u00a0<\/a><\/p>\n

Ross JE, Zhang BM, Lee K<\/strong>, Mohan S, Branchford BR, Bray P, Dugan SN, Freson K, Heller PG, Kahr WHA, Lambert MP, Luchtman-Jones L, Luo M, Perez Botero J, Rondina MT, Ryan G, Westbury S, Bergmeier W, Di Paola J.<\/p>\n

Blood Adv. 2021 Jan 26;5(2):414-431. doi: 10.1182\/bloodadvances.2020003712.<\/p>\n

PMID:\u00a033496739<\/p>\n

 <\/p>\n

Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice.\u00a0<\/a><\/p>\n

Smeekens JM, Johnson-Weaver BT, Hinton AL, Azcarate-Peril MA, Moran TP, Immormino RM, Kesselring JR, Steinbach EC, Orgel KA, Staats HF, Burks AW, Mucha PJ, Ferris MT,<\/strong> Kulis MD.<\/p>\n

Front Immunol. 2021 Jan 19;11:599637. doi: 10.3389\/fimmu.2020.599637. eCollection 2020.<\/p>\n

PMID:\u00a033542716<\/p>\n

 <\/p>\n

Reported differences in the flg22 response of the null mutation of AtRGS1 correlates with fixed genetic variation in the background of Col-0 isolates.\u00a0<\/a><\/p>\n

Ghusinga KR, Paredes F, Jones AM, Colaneri A<\/strong>.<\/p>\n

Plant Signal Behav. 2021 Jan 31:1878685. doi: 10.1080\/15592324.2021.1878685. Online ahead of print.<\/p>\n

PMID:\u00a033522388<\/p>\n

 <\/p>\n

Lymphatic Vasculature: An Emerging Therapeutic Target and Drug Delivery Route.\u00a0<\/a><\/p>\n

Xu W, Harris NR, Caron KM<\/strong>.<\/p>\n

Annu Rev Med. 2021 Jan 27;72:167-182. doi: 10.1146\/annurev-med-051419-114417.<\/p>\n

PMID:\u00a033502903<\/p>\n

 <\/p>\n

DeCompress: tissue compartment deconvolution of targeted mRNA expression panels using compressed sensing.\u00a0<\/a><\/p>\n

Bhattacharya A, Hamilton AM, Troester MA, Love MI<\/strong>.<\/p>\n

Nucleic Acids Res. 2021 Feb 1:gkab031. doi: 10.1093\/nar\/gkab031. Online ahead of print.<\/p>\n

PMID:\u00a033524140<\/p>\n

 <\/p>\n

A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks.\u00a0<\/a><\/p>\n

Hatkevich T<\/strong>, Miller DE, Turcotte CA<\/strong>, Miller MC, Sekelsky J<\/strong>.<\/p>\n

Nucleic Acids Res. 2021 Jan 25;49(2):879-890. doi: 10.1093\/nar\/gkaa1205.<\/p>\n

PMID:\u00a033406239<\/p>\n

 <\/p>\n

Fluent genomics with\u00a0\u00a0plyranges\u00a0<\/em>and\u00a0\u00a0tximeta<\/em>.\u00a0<\/a><\/p>\n

Lee S, Lawrence M, Love MI<\/strong>.<\/p>\n

F1000Res. 2020 Feb 12;9:109. doi: 10.12688\/f1000research.22259.1. eCollection 2020.<\/p>\n

PMID:\u00a032528659<\/p>\n","protected":false},"excerpt":{"rendered":"

Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 \u2013 Feb. 6, 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