Congratulations to Jeanne-Marie McPherson (Bob Duronio and Dan McKay labs), who was awarded an NRSA F31 predoctoral fellowship from the National Institute on Aging of the National Institutes of Health. Jeanne-Marie’s project is titled “Interrogating the roles of canonical versus variant histone H3 in genome function during aging.”     Please also see our page on Grants … Read more

Emma Hinkle (Jimena Giudice lab) published an article titled “Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins” in Communications Biology (DOI: 10.1038/s42003-022-03915-7). Image: Cartoon of how mechanosensitive targets might play a role in the MAPK signaling cascade (see article for details; click to enlarge). Please see our page on Publications …

Sarah Brotman (Karen Mohlke lab) and Hannah Wiedner (Jimena Giudice lab) were selected as winners of the Terry Magnuson Dissertation Award. This award, named in honor of the founding chair of the Department of Genetics at UNC, is given to one or two outstanding students in their final year of graduate study.

Congratulations to Nila Pazhayam (Jeff Sekelsky lab), who was awarded an NRSA F31 predoctoral fellowship from the National Institute on Aging of the National Institutes of Health.  Nila’s project is titled “Preventing Age-Associated Oocyte Aneuploidy: Mechanisms Behind the Drosophila melanogaster Centromere Effect.”   Please also see our page on Grants to GMB Students.

GMB students Sarah Brotman (Karen Mohlke lab) and Nisitha Sengottuvel (Chad Pecot lab) participated in the Shadow a Scientist program. Shadow A Scientist is a graduate-student run organization that plans and conducts outreach visits for underserved communities in NC. Sarah and Saygin participated in a Q&A session with students from East Burke High School in … Read more

Gabby Gentile (Jimena Giudice lab) published an article titled “The synaptosome-associated protein 23 (SNAP23) is necessary for proper myogenesis” in FASEB Journal (DOI: 10.1096/fj.202101627RR). GMB students Hannah Wiedner and Emma Hinkle are co-authors. Image: Reduced expression of the muscle differentiation marker MYH3 after siRNA knockdown of SNAP23 (see article for details; click to enlarge). Please see …

Emma Hinkle and Hannah Wiedner (Jimena Giudice lab) published an article titled “Alternative splicing regulation of membrane trafficking genes during myogenesis” in RNA (DOI: 10.1261/rna.078993.121). GMB student Gabrielle Gentile is a co-author. Image: Predicted motifs regulating alternative splicing of membrane trafficking genes.(see article for details; click to enlarge). Please see our page on Publications by …

Nate Diehl (Channing Der lab) published an article titled “The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer” in Journal of Biological Chemistry (DOI:10.1016/j.jbc.2021.101335). . Image: Inhibition of WEE1 + ERK1/2 arrests growth of PDAC organoids (see article for details; click to enlarge). Please see our page on Publications …