{"id":3901,"date":"2018-09-20T19:46:00","date_gmt":"2018-09-20T23:46:00","guid":{"rendered":"https:\/\/gmb.unc.edu\/?p=3901"},"modified":"2024-09-03T10:00:33","modified_gmt":"2024-09-03T14:00:33","slug":"john-noto-publishes-review-in-rna-biology-2-2-3","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/gmb\/2018\/09\/john-noto-publishes-review-in-rna-biology-2-2-3\/","title":{"rendered":"Matt Tegowski publishes paper in <em>Journal of Biological Chemistry<\/em>"},"content":{"rendered":"<p><span style=\"color: #ff0000\"><strong><a href=\"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-3902\" src=\"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018-284x300.jpg\" alt=\"\" width=\"83\" height=\"88\" srcset=\"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018-284x300.jpg 284w, https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018.jpg 355w\" sizes=\"auto, (max-width: 83px) 100vw, 83px\" \/><\/a>Matt Tegowski <\/strong><\/span>(<a href=\"https:\/\/baldwinlab.web.unc.edu\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff\"><span style=\"color: #0000ff\"><strong><em>Al Baldwin <\/em>lab<\/strong><\/span><\/span><\/a>) published a paper titled &#8220;<strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30131338\">Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2s<\/a>&#8220;<\/strong> in <span style=\"color: #008000\"><strong><span style=\"color: #008000\"><em>Journal of Biological Chemistry <\/em><\/span><\/strong><span style=\"color: #000000\"> (<span style=\"color: #ff00ff\"><strong><a style=\"color: #ff00ff\" href=\"https:\/\/doi.org\/10.1074\/jbc.RA118.003719\" target=\"_blank\" rel=\"noopener\">DOI: 10.1074\/jbc.RA118.003719<\/a><\/strong><\/span><\/span><\/span><span style=\"color: #008000\"><span style=\"color: #000000\">). <\/span><\/span>Image: Model describing mechanism of thioridazine effects on triple-negative breast cancer cell lines; see article for details.<\/p>\n<p>Please see our page on <strong><a title=\"Publications by GMB Students\" href=\"https:\/\/www.med.unc.edu\/gmb\/gmb-students\/student-publications\/\">Publications by <\/a><a title=\"Publications by GMB Students\" href=\"https:\/\/www.med.unc.edu\/gmb\/gmb-students\/student-publications\/\">GMB Students<\/a><\/strong> for more.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Matt Tegowski (Al Baldwin lab) published a paper titled &#8220;Thioridazine inhibits self-renewal in breast cancer cells via DRD2-dependent STAT3 inhibition, but induces a G1 arrest independent of DRD2s&#8220; in Journal of Biological Chemistry (DOI: 10.1074\/jbc.RA118.003719). Image: Model describing mechanism of thioridazine effects on triple-negative breast cancer cell lines; see article for details. Please see our &hellip; <a href=\"https:\/\/www.med.unc.edu\/gmb\/2018\/09\/john-noto-publishes-review-in-rna-biology-2-2-3\/\" aria-label=\"Read more about Matt Tegowski publishes paper in <em>Journal of Biological Chemistry<\/em>&#8220;>Read more<\/a><\/p>\n","protected":false},"author":2425,"featured_media":3902,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[10],"tags":[],"class_list":["post-3901","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","odd"],"acf":[],"featured_image":"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018.jpg","featured_image_medium":"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018-284x300.jpg","featured_image_medium_large":"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018.jpg","featured_image_large":"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018.jpg","featured_image_thumbnail":"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2018\/09\/Tegowski2018-150x150.jpg","featured_image_alt":"","category_details":[{"name":"Publication","link":"https:\/\/www.med.unc.edu\/gmb\/category\/publication\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/posts\/3901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/users\/2425"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/comments?post=3901"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/posts\/3901\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/media\/3902"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/media?parent=3901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/categories?post=3901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/gmb\/wp-json\/wp\/v2\/tags?post=3901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}