{"id":9317,"date":"2024-04-12T11:08:04","date_gmt":"2024-04-12T15:08:04","guid":{"rendered":"https:\/\/www.med.unc.edu\/gmb\/?post_type=ud_entry&#038;p=9317"},"modified":"2024-04-15T11:01:10","modified_gmt":"2024-04-15T15:01:10","slug":"katie-baldwin-phd","status":"publish","type":"ud_entry","link":"https:\/\/www.med.unc.edu\/gmb\/people\/katie-baldwin-phd\/","title":{"rendered":"Katie Baldwin, PhD"},"content":{"rendered":"<ul class=\"faculty-training\">\n<li style=\"line-height: 1.1; font-size: small; color: #333;\">Mentorship Training Completions:<\/li>\n<li><a href=\"https:\/\/ogefacultymentoring.web.unc.edu\/\"><img decoding=\"async\" src=\"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2024\/03\/Faculty-OGE-Trained-mentor-badge.svg\" alt=\"OGE Mentoring Workshop Badge\" class=\"aligncenter size-full wp-image-9189\" \/><\/a><\/li>\n<li><a href=\"https:\/\/lgbtq.unc.edu\/programs\/programs-education\/safe-zone\/\"><img decoding=\"async\" src=\"https:\/\/www.med.unc.edu\/gmb\/wp-content\/uploads\/sites\/1391\/2024\/03\/unc-safe-zone-training-badge.svg\" alt=\"Safe Zone Training Badge\" class=\"aligncenter size-full wp-image-9188\" \/><\/a><\/li>\n<\/ul>\n<ul class=\"department-affiliations\">\n<li style=\"line-height: 1.1; font-size: small; color: #333;\">Department Affiliations:<\/li>\n<li style=\"\">Cell Biology & Physiology<\/li>\n<\/ul>\n<hr \/>\n\n<p>Dr. Baldwin is an assistant professor in the Department of Cell Biology and Physiology and a member of the Neuroscience Center. A native Michigander, Dr. Baldwin completed her undergraduate and graduate training at the University of Michigan, followed by her postdoctoral training in Dr. Cagla Eroglu\u2019s laboratory at Duke University. Outside of the lab, she enjoys mountain biking, running, and being a mom.<\/p>\n<h2>My Research<\/h2>\n<p>Building a functioning brain requires the establishment of an elaborate network of interactions between neurons and non-neuronal glial cells. Defects in neuron-glia interactions are implicated in many neurological disorders, including autism, schizophrenia, Alzheimer\u2019s Disease, neurodegeneration, neuropathic pain, and neuroimmune disorders. Astrocytes, a major glial cell type in the brain, are morphologically complex cells that extensively infiltrate the neuropil to directly interact with neurons and all other brain cell types. Through this extensive network of interactions, astrocytes control a wide variety of processes that are fundamentally important for proper brain development and function, including synapse formation, regulation of neurotransmission, and establishment of the blood-brain barrier. Despite the many important roles of astrocytes in the brain, we still have a limited understanding of the mechanisms that regulate the development of astrocytes and their interactions with other cells. Moreover, we do not know how defects in these processes drive neurological dysfunction. To address these important knowledge gaps, my laboratory is investigating fundamental aspects of astrocyte cell biology to understand how astrocytes, through their interactions with other brain cell types, regulate brain development and function. Furthermore, we study how astrocyte dysfunction drives the pathogenesis of neurological disorders such as autism, schizophrenia, and leukodystrophy. We use a variety techniques, including mouse genetics, primary cell culture, quantitative proteomics, molecular biology, and super resolution microscopy to probe the function of astrocytes during brain development and disease.<\/p>\n","protected":false},"featured_media":9353,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"ud_division":[37],"faculty-mentorship-training":[43,44],"class_list":["post-9317","ud_entry","type-ud_entry","status-publish","format-standard","has-post-thumbnail","hentry","ud_division-faculty","faculty-mentorship-training-oge-mentoring-workshop","faculty-mentorship-training-safe-zone-training","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Katie Baldwin, PhD - Genetics and Molecular Biology Curriculum<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/gmb\/people\/katie-baldwin-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Katie Baldwin, PhD - Genetics and Molecular Biology Curriculum\" \/>\n<meta property=\"og:description\" content=\"Dr. Baldwin is an assistant professor in the Department of Cell Biology and Physiology and a member of the Neuroscience Center. A native Michigander, Dr. Baldwin completed her undergraduate and graduate training at the University of Michigan, followed by her postdoctoral training in Dr. Cagla Eroglu\u2019s laboratory at Duke University. 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