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Research Associate

Selected Bibliography:

  1. Tyrrell J, Ghosh A, Manzo ND, Randell SH, Tarran R. Evaluation of chronic cigarette smoke exposure in human bronchial epithelial cultures. J Appl Toxicol. 2023 Jan 3. doi: 10.1002/jat.4430. Epub ahead of print. PMID: 36594405.
  2. Abdelwahab S, Ghosh A, Wrennall J, Tarran R. Vaping /E-liquid Exposure Causes Dysregulation of Neutrophil Extracellular Trap formation. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7511. PMID: 35556998.
  3. Wu T, Goriounova AS, Worthington EN, Wrennall JA, Ghosh A, Ahmad S, Flori Sassano M, Tarran R. SPLUNC1 is a negative regulator of the Orai1 Ca2+ channel. Physiol Rep. 2022 May;10(10):e15306. doi: 10.14814/phy2.15306. PMID: 35581745; PMCID: PMC9114653.
  4. Wrennall JA, Ahmad S, Worthington EN, Wu T, Goriounova AS, Voeller AS, Stewart IE, Ghosh A, Krajewski K, Tilley SL, Hickey AJ, Sassano MF, Tarran R. A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model. Am J Respir Cell Mol Biol. 2022 Mar;66(3):271-282. doi: 10.1165/rcmb.2020-0452OC. PMID: 34807800. PMCID: PMC8937239.
  5. Davis ES, Ghosh A, Coakley RD, Wrennall JA, Lubamba BA, Rowell TR, Dang H, Pawlak EA, Li Q, Alexis NE, Ribeiro CMP, Tarran R. Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression. Nicotine Tob Res. 2022 Feb 14;24(3):395-399. doi: 10.1093/ntr/ntab186. PMID: 34519792; PMCID: PMC8842413.
  6. Neczypor EW, Mears MJ, Ghosh A, Sassano MF, Gumina RJ, Wold LE, Tarran R. E-Cigarettes and Cardiopulmonary Health: Review for Clinicians. Circulation. 2022 Jan 18;145(3):219-232. doi: 10.1161/CIRCULATIONAHA.121.056777. PMID: 35041473; PMCID: PMC8820458.
  7. Ghosh A, Girish V, Yuan ML, Coakley RD, Wrennall JA, Alexis NE, Sausville EL, Vasudevan A, Chait AR, Sheltzer JM, Tarran R. Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding. Am J Respir Crit Care Med. 2022 Jan 1;205(1):129-133. doi: 10.1164/rccm.202106-1377LE. PMID: 34748720. PMCID: PMC8865588.
  8. Raha S, Ghosh A, Dutta D, Patel DR, Pahan K. Activation of PPARα enhances astroglial uptake and degradation of β-amyloid. Sci Signal. 2021 Oct 26;14(706):eabg4747. doi: 10.1126/scisignal.abg4747. PMID: 34699252; PMCID: PMC8793854.
  9. Ghosh A, Ahmad S, Coakley RD, Sassano MF, Alexis NE, Tarran R. Lipid-laden Macrophages Are Not Unique to Patients with E-Cigarette or Vaping Product Use-associated Lung Injury. Am J Respir Crit Care Med. 2021 Apr 15;203(8):1030-1033. doi: 10.1164/rccm.202009-3507LE. PMID: 33332247; PMCID: PMC8048758.
  10. Ghosh A, Beyazcicek O, Davis ES, Onyenwoke RU, Tarran R. Cellular effects of nicotine salt-containing e-liquids. J Appl Toxicol. 2021 Mar;41(3):493-505. doi: 10.1002/jat.4060. PMID: 33034066.
  11. Abdelwahab SH, Reidel B, Martin JR, Ghosh A, Keating JE, Haridass P, Carpenter J, Glish GL, Tarran R, Doerschuk CM, Kesimer M. Cigarillos Compromise the Mucosal Barrier and Protein Expression in Airway Epithelia. Am J Respir Cell Mol Biol. 2020 Dec;63(6):767-779. doi: 10.1165/rcmb.2019-0085OC. PMID: 32877614; PMCID: PMC7790145.
  12. Ghosh A, Coakley RD, Ghio AJ, Muhlebach MS, Esther Jr. CR, Alexis NE and Tarran R. Chronic E-Cigarette Use Increases Neutrophil Elastase and Matrix Metalloprotease Levels in the Lung. Am J Respir Crit Care Med. 2019 Dec 1;200(11):1392-1401. doi: 10.1164/rccm.201903-0615OC. PMID: 31390877; PMCID: PMC6884043.
  13. Ghosh A*, Coakley RD*, Mascenik T, Rowell TR, Davis ES, Rogers K, Webster MJ, Dang H, Herring LE, Sassano MF, Livraghi-Butrico A, Van Buren SK, Graves LM, Herman MA, Randell SH, Alexis NE and Tarran R. Chronic E-cigarette Exposure Alters the Human Bronchial Epithelial Proteome. Am J Respir Crit Care Med. 2018 Jul 1;198(1):67-76. doi: 10.1164/rccm.201710-2033OC. PMID: 29481290; PMCID: PMC6034122.
  14. Ghosh A, Abdelwahab SH, Reeber SL, Reidel B, Marklew AJ, Garrison AJ, Lee S, Dang H, Herring AH, Glish GL, Kesimer M, and Tarran R. Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression. Sci Rep. 2017 Apr 27;7:46239. doi: 10.1038/srep46239. PMID: 28447619; PMCID: PMC5406835.
  15. Ghosh A, Nethery RC, Herring AH, and Tarran R. Flavored little cigar smoke induces cytotoxicity and apoptosis in airway epithelia. Cell Death Discov. 2017 Apr 24;3:17019. doi: 10.1038/cddiscovery.2017.19. PMID: 28496992; PMCID: PMC5402522.
  16. Ghosh A, Banerjee S, Mitra A, Muralidharan M, Roy B, Banerjee R, Mandal AK, and Chatterjee IB. Interaction of p-benzoquinone with hemoglobin in smoker’s blood causes alteration of structure and loss of oxygen binding capacity. Toxicol Rep. 2016 Feb 9;3:295-305. doi: 10.1016/j.toxrep.2016.02.001. PMID: 28959550; PMCID: PMC5615826.
  17. Ghosh A, Boucher RC, and Tarran R. Airway hydration and COPD. Cell Mol Life Sci. 2015 Oct;72(19):3637-52. doi: 10.1007/s00018-015-1946-7. PMID: 26068443; PMCID: PMC4567929.
  18. Ghosh A, Choudhury A, Das A, Chatterjee NS, Das T, Chowdhury R, Panda K, Banerjee R, and Chatterjee IB. Cigarette smoke induces p-benzoquinone-albumin adduct in blood serum: Implications on structure and ligand binding properties. Toxicology. 2012 Feb 26;292(2-3):78-89. doi: 10.1016/j.tox.2011.11.014. PMID: 22154986.
Arunava Ghosh