{"id":6309,"date":"2024-10-18T16:10:43","date_gmt":"2024-10-18T20:10:43","guid":{"rendered":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/?post_type=directory&p=6309"},"modified":"2025-03-12T16:45:48","modified_gmt":"2025-03-12T20:45:48","slug":"ray-caldwell-phd","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/directory\/ray-caldwell-phd\/","title":{"rendered":"Ray Caldwell, PhD"},"content":{"rendered":"

Specialty Areas:<\/h2>\n

Electrophysiology<\/p>\n

Education:<\/h2>\n

PhD<\/strong>, Medical College of Virginia, Virginia Commonwealth University (1997)<\/p>\n

Selected Bibliography:<\/h2>\n
    \n
  1. Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA<\/strong>, Burns KA, Esther CR Jr, Mall MA, Boucher RC, O’Neal WK, Grubb BR. Lung disease phenotypes caused by overexpression of combinations of \u03b1-, \u03b2-, and \u03b3-subunits of the epithelial sodium channel in mouse airways<\/a>. Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L318-L331. doi: 10.1152\/ajplung.00382.2017. PMID: 29074490; PMCID: PMC5866504.<\/li>\n
  2. Caldwell RA<\/strong>, Grove DE, Houck SA, Cyr DM. Increased folding and channel activity of a rare cystic fibrosis mutant with CFTR modulators<\/a>. Am J Physiol Lung Cell Mol Physiol. 2011 Sep;301(3):L346-52. doi: 10.1152\/ajplung.00044.2011. PMID: 21642448; PMCID: PMC3174745.<\/li>\n
  3. Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA<\/strong>, Schubert SC, Schultz C, O’Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC. Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice<\/a>. J Biol Chem. 2010 Aug 27;285(35):26945-26955. doi: 10.1074\/jbc.M110.151803. PMID: 20566636; PMCID: PMC2930694.<\/li>\n
  4. Hirsh AJ, Zhang J, Zamurs A, Fleegle J, Thelin WR, Caldwell RA<\/strong>, Sabater JR, Abraham WM, Donowitz M, Cha B, Johnson KB, St George JA, Johnson MR, Boucher RC. Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N’-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease<\/a>. J Pharmacol Exp Ther. 2008 Apr;325(1):77-88. doi: 10.1124\/jpet.107.130443. PMID: 18218832.<\/li>\n
  5. Caldwell RA<\/strong>, Boucher RC, Stutts MJ. Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport<\/a>. Am J Physiol Lung Cell Mol Physiol. 2005 May;288(5):L813-9. doi: 10.1152\/ajplung.00435.2004. PMID: 15640288.<\/li>\n
  6. Caldwell RA<\/strong>, Boucher RC, Stutts MJ. Serine protease activation of near-silent epithelial Na+ channels<\/a>. Am J Physiol Cell Physiol. 2004 Jan;286(1):C190-4. doi: 10.1152\/ajpcell.00342.2003. PMID: 12967915.<\/li>\n
  7. Caldwell RA<\/strong>, Grubb BR, Tarran R, Boucher RC, Knowles MR, Barker PM. In vivo airway surface liquid Cl- analysis with solid-state electrodes<\/a>. J Gen Physiol. 2002 Jan;119(1):3-14. doi: 10.1085\/jgp.119.1.3. PMID: 11773234; PMCID: PMC2233861.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Specialty Areas: Electrophysiology Education: PhD, Medical College of Virginia, Virginia Commonwealth University (1997) Selected Bibliography: Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA, Burns KA, Esther CR Jr, Mall MA, Boucher RC, O’Neal WK, Grubb BR. Lung disease phenotypes caused by overexpression of combinations of \u03b1-, \u03b2-, and \u03b3-subunits of the … Read more<\/a><\/p>\n","protected":false},"featured_media":6310,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_links_to":"","_links_to_target":""},"class_list":["post-6309","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"yoast_head":"\nRay Caldwell, PhD | Marsico Lung Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/directory\/ray-caldwell-phd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ray Caldwell, PhD | Marsico Lung Institute\" \/>\n<meta property=\"og:description\" content=\"Specialty Areas: Electrophysiology Education: PhD, Medical College of Virginia, Virginia Commonwealth University (1997) Selected Bibliography: Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA, Burns KA, Esther CR Jr, Mall MA, Boucher RC, O’Neal WK, Grubb BR. 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