{"id":626,"date":"2014-01-16T05:00:00","date_gmt":"2014-01-16T10:00:00","guid":{"rendered":"https:\/\/med.sites.unc.edu\/cfpulmcenter\/unc-researchers-collaborate-on-new-nature-paper\/"},"modified":"2017-12-18T10:04:20","modified_gmt":"2017-12-18T15:04:20","slug":"unc-researchers-collaborate-on-new-nature-paper","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/","title":{"rendered":"UNC Researchers Collaborate on New Nature Paper"},"content":{"rendered":"<p><!-- description --><\/p>\n<p class=\"lead\">\n<div class=\"image-section\">\n<\/div>\n<p>CF Center members Drs. Alessandra Livraghi-Butrico, Bill Davis, Kristy Terrell, Barbara Grubb, and Wanda O&#8217;Neal collaborated with researchers on a new <em>Nature<\/em> paper, &#8220;Muc5b is required for airway defence.&#8221;<\/p>\n<p>In their study, Roy et al., found that mouse Muc5b, but not Muc5ac, is required for mucociliary clearance and control of infections in the airways and middle ear. These findings highlight a specific role for Muc5b in mucosal immune homeostasis and provide a refined framework for designing targeted therapies to control mucin secretion and restore mucociliary clearance.<\/p>\n<p><span style=\"line-height: 1.43em; \">The paper can be found online at <em><a class=\"external-link\" href=\"http:\/\/www.nature.com\/nature\/journal\/v505\/n7483\/full\/nature12807.html\" target=\"_blank\" title=\"Muc5b paper\">Nature<\/a><\/em> or <a class=\"external-link\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24317696\" target=\"_blank\" title=\"Muc5b PubMed\">PubMed<\/a>.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CF Center members Drs. Alessandra Livraghi-Butrico, Bill Davis, Kristy Terrell, Barbara Grubb, and Wanda O&#8217;Neal collaborated with researchers on a new Nature paper, &#8220;Muc5b is required for airway defence.&#8221; In their study, Roy et al., found that mouse Muc5b, but not Muc5ac, is required for mucociliary clearance and control of infections in the airways and &hellip; <a href=\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\" aria-label=\"Read more about UNC Researchers Collaborate on New Nature Paper\">Read more<\/a><\/p>\n","protected":false},"author":10193,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-626","post","type-post","status-publish","format-standard","hentry","category-news","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>UNC Researchers Collaborate on New Nature Paper | Marsico Lung Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"UNC Researchers Collaborate on New Nature Paper | Marsico Lung Institute\" \/>\n<meta property=\"og:description\" content=\"CF Center members Drs. Alessandra Livraghi-Butrico, Bill Davis, Kristy Terrell, Barbara Grubb, and Wanda O&#8217;Neal collaborated with researchers on a new Nature paper, &#8220;Muc5b is required for airway defence.&#8221; In their study, Roy et al., found that mouse Muc5b, but not Muc5ac, is required for mucociliary clearance and control of infections in the airways and &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\" \/>\n<meta property=\"og:site_name\" content=\"Marsico Lung Institute\" \/>\n<meta property=\"article:published_time\" content=\"2014-01-16T10:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-12-18T15:04:20+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\"},\"author\":{\"name\":\"\",\"@id\":\"\"},\"headline\":\"UNC Researchers Collaborate on New Nature Paper\",\"datePublished\":\"2014-01-16T10:00:00+00:00\",\"dateModified\":\"2017-12-18T15:04:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\"},\"wordCount\":108,\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\",\"url\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\",\"name\":\"UNC Researchers Collaborate on New Nature Paper | Marsico Lung Institute\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/#website\"},\"datePublished\":\"2014-01-16T10:00:00+00:00\",\"dateModified\":\"2017-12-18T15:04:20+00:00\",\"author\":{\"@id\":\"\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"UNC Researchers Collaborate on New Nature Paper\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/\",\"name\":\"Marsico Lung Institute\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"\",\"url\":\"https:\/\/www.med.unc.edu\/marsicolunginstitute\/author\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"UNC Researchers Collaborate on New Nature Paper | Marsico Lung Institute","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/","og_locale":"en_US","og_type":"article","og_title":"UNC Researchers Collaborate on New Nature Paper | Marsico Lung Institute","og_description":"CF Center members Drs. Alessandra Livraghi-Butrico, Bill Davis, Kristy Terrell, Barbara Grubb, and Wanda O&#8217;Neal collaborated with researchers on a new Nature paper, &#8220;Muc5b is required for airway defence.&#8221; In their study, Roy et al., found that mouse Muc5b, but not Muc5ac, is required for mucociliary clearance and control of infections in the airways and &hellip; Read more","og_url":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/","og_site_name":"Marsico Lung Institute","article_published_time":"2014-01-16T10:00:00+00:00","article_modified_time":"2017-12-18T15:04:20+00:00","twitter_card":"summary_large_image","twitter_misc":{"Written by":"","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/#article","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/"},"author":{"name":"","@id":""},"headline":"UNC Researchers Collaborate on New Nature Paper","datePublished":"2014-01-16T10:00:00+00:00","dateModified":"2017-12-18T15:04:20+00:00","mainEntityOfPage":{"@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/"},"wordCount":108,"articleSection":["News"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/","url":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/","name":"UNC Researchers Collaborate on New Nature Paper | Marsico Lung Institute","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/#website"},"datePublished":"2014-01-16T10:00:00+00:00","dateModified":"2017-12-18T15:04:20+00:00","author":{"@id":""},"breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/unc-researchers-collaborate-on-new-nature-paper\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/"},{"@type":"ListItem","position":2,"name":"UNC Researchers Collaborate on New Nature Paper"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/#website","url":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/","name":"Marsico Lung Institute","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"","url":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/author\/"}]}},"featured_image":false,"featured_image_medium":false,"featured_image_medium_large":false,"featured_image_large":false,"featured_image_thumbnail":false,"featured_image_alt":false,"category_details":[{"name":"News","link":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/category\/news\/"}],"tag_details":[],"_links_to":[],"_links_to_target":[],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/posts\/626","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/users\/10193"}],"replies":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/comments?post=626"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/posts\/626\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/media?parent=626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/categories?post=626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/marsicolunginstitute\/wp-json\/wp\/v2\/tags?post=626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}